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Dr Lucy Brunt

Postdoctoral Research Associate

 -

 Living Systems Institute 

 

Living Systems Institute, University of Exeter, Stocker Road, Exeter, EX4 4QD

Overview

During my PhD at the University of Bristol, I became interested in the role of Wnt signalling and biomechanics in tissue morphogenesis, in particular, during zebrafish jaw joint morphogenesis. My current project, here at the Living Systems Institute at the University of Exeter, is to investigate the molecular mechanisms underlying the formation and control of Wnt positive signalling filopodia- also known as cytonemes- during brain development.

Qualifications

2011 - Biomedical Science, BSc, University of Sheffield

2015 - Wellcome Trust Dynamic Cell Biology PhD, University of Bristol

Career

2015-2017 Postdoctoral Research Associate, Dr. Chrissy Hammond Lab, University of Bristol

2017-Present  Postdoctoral Research Associate, Prof. Steffen Scholpp Lab, University of Exeter

Research

Research interests

During my PhD at the University of Bristol, I became interested in the role of Wnt signalling and biomechanics in tissue morphogenesis, in particular, during zebrafish jaw joint morphogenesis. My current project, here at the Living Systems Institute at the University of Exeter, is to investigate the molecular mechanisms underlying the formation and control of Wnt positive signalling filopodia- also known as cytonemes- during brain development.

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Gardilla AC, Sanchez D, Brunt L, Scholpp S (In Press). From top to bottom: Cell polarity in Hedgehog and Wnt trafficking. BMC Biology Full text.
Brunt L, Scholpp S (2018). The function of endocytosis in Wnt signaling. Cellular and Molecular Life Sciences, 75(5), 785-795. Abstract.  Full text.
Brunt LH, Begg K, Kague E, Cross S, Hammond CL (2017). Wnt signalling controls the response to mechanical loading during zebrafish joint development. Development, 144(15), 2798-2809.
Brunt LH, Roddy KA, Rayfield EJ, Hammond CL (2016). Building Finite Element Models to Investigate Zebrafish Jaw Biomechanics. Journal of Visualized Experiments(118).
Brunt L, Skinner R, Roddy K, Araujo N, Rayfield E, Hammond C (2016). Differential effects of altered patterns of movement and strain on joint cell behaviour and skeletal morphogenesis. Osteoarthritis and Cartilage, 24(11), 1940-1950.
Brunt LH, Norton JL, Bright JA, Rayfield EJ, Hammond CL (2015). Finite element modelling predicts changes in joint shape and cell behaviour due to loss of muscle strain in jaw development. Journal of Biomechanics, 48(12), 3112-3122.
Mitchell R, Huitema L, Skinner R, Brunt L, Severn C, Schulte-Merker S, Hammond C (2013). New tools for studying osteoarthritis genetics in zebrafish. Osteoarthritis and Cartilage, 21(2), 269-278.

Publications by year


In Press

Gardilla AC, Sanchez D, Brunt L, Scholpp S (In Press). From top to bottom: Cell polarity in Hedgehog and Wnt trafficking. BMC Biology Full text.

2018

Brunt L, Scholpp S (2018). The function of endocytosis in Wnt signaling. Cellular and Molecular Life Sciences, 75(5), 785-795. Abstract.  Full text.

2017

Brunt LH, Begg K, Kague E, Cross S, Hammond CL (2017). Wnt signalling controls the response to mechanical loading during zebrafish joint development. Development, 144(15), 2798-2809.

2016

Brunt LH, Roddy KA, Rayfield EJ, Hammond CL (2016). Building Finite Element Models to Investigate Zebrafish Jaw Biomechanics. Journal of Visualized Experiments(118).
Brunt L, Skinner R, Roddy K, Araujo N, Rayfield E, Hammond C (2016). Differential effects of altered patterns of movement and strain on joint cell behaviour and skeletal morphogenesis. Osteoarthritis and Cartilage, 24(11), 1940-1950.

2015

Brunt LH, Norton JL, Bright JA, Rayfield EJ, Hammond CL (2015). Finite element modelling predicts changes in joint shape and cell behaviour due to loss of muscle strain in jaw development. Journal of Biomechanics, 48(12), 3112-3122.

2013

Mitchell R, Huitema L, Skinner R, Brunt L, Severn C, Schulte-Merker S, Hammond C (2013). New tools for studying osteoarthritis genetics in zebrafish. Osteoarthritis and Cartilage, 21(2), 269-278.

Lucy_Brunt Details from cache as at 2018-12-09 15:04:11

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Teaching

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