Dr Matthew Robinson
I am interested in the interactions of pathogens with their hosts and vectors, particularly bacteria of human and animal importance. I currently study two-component systems (TCS) and their role in virulence and niche adaptation of pathogenic bacteria, in particular members of the Burkholderia cepacia complex and Pseudomonas aeruginosa. These bacteria can cause serious life-threatening pneumonia in cystic fibrosis patients and are highly drug-resistant.
To study the interactions and effects of two-component systems I employ a variety of microbiological and molecular techniques including:
- Disruption and deletion of specific TCS genes
- A variety of phenotypic assays
- Gene expression studies using RT-PCR, qPCR, RNA-seq and ChIP-seq
- Protein expression and biochemical pathways.
2003: B.Sc. (hons) Marine & Freshwater Biology, University of Wales, Aberystwyth.
2005: M.Sc. Veterinary Parasitology, Liverpool School of Tropical Medicine.
2009: Ph.D. Investigating the dynamics of vector-borne pathogens during ecto-parasite feeding, University of Bristol.
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