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Dr Mark van der Giezen

Dr Mark van der Giezen

Senior Lecturer in Evolutionary Biochemistry

3483

Geoffrey Pope MO5

Geoffrey Pope Building
University of Exeter
Stocker Road
Exeter
EX4 4QD
UK

Microbes play important roles in human and animal health. Especially the microbes in guts are of crucial importance. We are interested in how these microbes, that live in the absence of oxygen, affect human and animal health. Research includes important human and animal pathogens but also focusses on microbes and nutrition and their role in food security.

Adaptation of microbial eukaryotes to low oxygen or complete lack of oxygen featured in several high impact publications (Nature (2003) 426, 172-176Current Biology (2008) 18, 580-585, Current Biology (2014) 24, 1176-1186 and PLoS Biology (2017) 15(9) e2003769) and included major human pathogens such as Giardia intestinalisEntamoeba histolytica and Blastocystis. We hope that understanding their unusual biochemistry might lead to new drug targets. 

Food security research focusses at biochemistry and genomics of several important pathogens such as Aphanomyces and Fasciola hepaticaAphanomyces causes two notifyable diseases: crayfish plague and epizootic ulcerative syndrome in fish while Fasciola causes liverfluke in cattle and sheep. 

Understanding how environmental microbes affect food productivity and human health is studied using environmental genomics and next generation sequencing.

A recent new research direction involves the use of algae to regenerate mine waste, this is an extension of our involvement in the genome of Emiliania huxleyi (Nature (2013) 499, 209-213). This work is part of the GW4+ AVaRICE project.

Our lab uses a variety of techniques to answer our research questions. Molecular biology, cell biology, biochemistry, bioinformatics and next-generation sequencing methods are routinely used. 

Qualifications

2007 Certificate in Academic Practice, Queen Mary, University of London
1992-1997 PhD in Mathematical and Natural Sciences, University of Groningen
1988-1992 Drs Molecular Biology & Immunology, University of Groningen

Career

2014 Elected Fellow of the Linnean Society of London

2012 Nominated for President for the International Society of Protistologists (ISOP)

2009 Visiting Scholar at the Institute for Protein Research, University of Osaka, Japan
2007-present Senior Lecturer in Evolutionary Biochemistry, School of Biosciences, University of Exeter
2004-2007 Lecturer in Microbiology, School of Biological and Chemical Sciences, Queen Mary, University of London
2002-2004 Postdoctoral Research Fellow, School of Biological Sciences, Royal Holloway, University of London
1998 EMBO Fellow
1997-2002 Postdoctoral Research Fellow, Department of Zoology, The Natural History Museum, London
1996 Visiting Scientist, Centre for the Study of Metals in Biology and Medicine, King‘s College, London
1992 Erasmus Studentship, Laboratoire de Microbiologie et Génétique Moléculaires, University Paul Sabatier, Toulouse

Links

Keeping the parasites alive (only if none of my people are around).

Research

Research interests

Microbes play important roles in human and animal health. Especially the microbes in guts are of crucial importance. We are interested in how these microbes, that live in the absence of oxygen, affect human and animal health. Research includes important human and animal pathogens but also focusses on microbes and nutrition and their role in food security.

Adaptation of microbial eukaryotes to low oxygen or complete lack of oxygen featured in several high impact publications (Nature (2003) 426, 172-176Current Biology (2008) 18, 580-585, Current Biology (2014) 24, 1176-1186 and PLoS Biology (2017) 15(9) e2003769) and included major human pathogens such as Giardia intestinalisEntamoeba histolytica and Blastocystis. We hope that understanding their unusual biochemistry might lead to new drug targets. 

Food security research focusses at biochemistry and genomics of several important pathogens such as Aphanomyces and Fasciola hepaticaAphanomyces causes two notifyable diseases: crayfish plague and epizootic ulcerative syndrome in fish while Fasciola causes liverfluke in cattle and sheep. 

Understanding how environmental microbes affect food productivity and human health is studied using environmental genomics and next generation sequencing.

A recent new research direction involves the use of algae to regenerate mine waste, this is an extension of our involvement in the genome of Emiliania huxleyi (Nature (2013) 499, 209-213). This work is part of the GW4+ AVaRICE project.

Our lab uses a variety of techniques to answer our research questions. Molecular biology, cell biology, biochemistry, bioinformatics and next-generation sequencing methods are routinely used. 

Links


Key publications | Publications by category | Publications by year

Key publications


Vashisht K, Verma S, Gupta S, Lynn AM, Dixit R, Mishra N, Valecha N, Hamblin KA, Maytum R, Pandey KC, et al (2017). Engineering Nucleotide Specificity of Succinyl-CoA Synthetase in. Blastocystis : the Emerging Role of Gatekeeper Residues. Biochemistry, 56(3), 534-542. Full text.
Gentekaki E, Curtis BA, Stairs CW, Klimeš V, Eliáš M, Salas-Leiva DE, Herman EK, Eme L, Arias MC, Henrissat B, et al (2017). Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis. PLoS Biol, 15(9). Abstract.  Author URL.  Full text.
Herman E, Siegesmund MA, Bottery MJ, van Aerle R, Shather MM, Caler E, Dacks JB, van der Giezen M (2017). Membrane Trafficking Modulation during Entamoeba Encystation. SCIENTIFIC REPORTS, 7 Author URL.  Full text.
Stairs CW, Eme L, Brown MW, Mutsaers C, Susko E, Dellaire G, Soanes DM, Van Der Giezen M, Roger AJ (2014). A SUF Fe-S cluster biogenesis system in the mitochondrion-related organelles of the anaerobic protist Pygsuia. Current Biology, 24(11), 1176-1186. Abstract.
Müller M, Mentel M, van Hellemond JJ, Henze K, Woehle C, Gould SB, Yu R-Y, van der Giezen M, Tielens AGM, Martin WF, et al (2012). Biochemistry and evolution of anaerobic energy metabolism in eukaryotes. Microbiol Mol Biol Rev, 76(2), 444-495. Abstract.  Author URL.
Maralikova B, Ali V, Nakada-Tsukui K, Nozaki T, van der Giezen M, Henze K, Tovar J (2010). Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria. Cell Microbiol, 12(3), 331-342. Abstract.  Author URL.  Full text.

Publications by category


Books

van der Giezen, M. (2007). Protein targeting protocols., Humana Press Inc.

Journal articles

Vashisht K, Verma S, Gupta S, Lynn AM, Dixit R, Mishra N, Valecha N, Hamblin KA, Maytum R, Pandey KC, et al (2017). Engineering Nucleotide Specificity of Succinyl-CoA Synthetase in. Blastocystis : the Emerging Role of Gatekeeper Residues. Biochemistry, 56(3), 534-542. Full text.
Gentekaki E, Curtis BA, Stairs CW, Klimeš V, Eliáš M, Salas-Leiva DE, Herman EK, Eme L, Arias MC, Henrissat B, et al (2017). Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis. PLoS Biol, 15(9). Abstract.  Author URL.  Full text.
Herman E, Siegesmund MA, Bottery MJ, van Aerle R, Shather MM, Caler E, Dacks JB, van der Giezen M (2017). Membrane Trafficking Modulation during Entamoeba Encystation. SCIENTIFIC REPORTS, 7 Author URL.  Full text.
van der Giezen M (2016). Evolution: Organelles Caught in the Act. Curr Biol, 26(20), R913-R915. Abstract.  Author URL.
van der Giezen M (2015). Nature's Magic Algebra; or, How One Plus One Still Equaled One. BioScience, 65(8), 832-833.
Stairs CW, Eme L, Brown MW, Mutsaers C, Susko E, Dellaire G, Soanes DM, Van Der Giezen M, Roger AJ (2014). A SUF Fe-S cluster biogenesis system in the mitochondrion-related organelles of the anaerobic protist Pygsuia. Current Biology, 24(11), 1176-1186. Abstract.
Bertolini C, van Aerle R, Lampis S, Moore KA, Paszkiewicz K, Butler CS, Vallini G, van der Giezen M (2014). Draft Genome Sequence of Stenotrophomonas maltophilia SeITE02, a Gammaproteobacterium Isolated from Selenite-Contaminated Mining Soil. Genome Announc, 2(3). Abstract.  Author URL.
van der Giezen M (2013). Evolution: one thread to unite them all. Curr Biol, 23(16), R679-R681. Abstract.  Author URL.
Koumandou VL, Wickstead B, Ginger ML, van der Giezen M, Dacks JB, Field MC (2013). Molecular paleontology and complexity in the last eukaryotic common ancestor. Crit Rev Biochem Mol Biol, 48(4), 373-396. Abstract.  Author URL.
Read BA, Kegel J, Klute MJ, Kuo A, Lefebvre SC, Maumus F, Mayer C, Miller J, Monier A, Salamov A, et al (2013). Pan genome of the phytoplankton Emiliania underpins its global distribution. Nature, 499(7457), 209-213. Abstract.  Author URL.
Clark CG, van der Giezen M, Alfellani MA, Stensvold CR (2013). Recent developments in Blastocystis research. Adv Parasitol, 82, 1-32. Abstract.  Author URL.
Terali K, Beavil RL, Pickersgill RW, van der Giezen M (2013). The effect of the adaptor protein Isd11 on the quaternary structure of the eukaryotic cysteine desulphurase Nfs1. Biochem Biophys Res Commun, 440(2), 235-240. Abstract.  Author URL.
Müller M, Mentel M, van Hellemond JJ, Henze K, Woehle C, Gould SB, Yu R-Y, van der Giezen M, Tielens AGM, Martin WF, et al (2012). Biochemistry and evolution of anaerobic energy metabolism in eukaryotes. Microbiol Mol Biol Rev, 76(2), 444-495. Abstract.  Author URL.
Standley DM, van der Giezen M (2012). Modeling the alternative oxidase from the human pathogen Blastocystis using automated hybrid structural template assembly. Research and Reports in Biochemistry, 2, 1-8. Abstract.  Author URL.
van der Giezen M, Lenton TM (2012). The rise of oxygen and complex life. Journal of Eukaryotic Microbiology, 59(2), 111-113.
van der Giezen M (2011). Mitochondria and the Rise of Eukaryotes. BIOSCIENCE, 61(8), 594-601. Author URL.
Siegesmund MA, Hehl AB, van der Giezen M (2011). Mitosomes in trophozoites and cysts of the reptilian parasite Entamoeba invadens. Eukaryot Cell, 10(11), 1582-1585. Abstract.  Author URL.
Herman EK, Walker G, van der Giezen M, Dacks JB (2011). Multivesicular bodies in the enigmatic amoeboflagellate Breviata anathema and the evolution of ESCRT 0. Journal of Cell Science, 124, 613-621. Abstract.
Griffith GW, Baker S, Fliegerova K, Liggenstoffer A, van der Giezen M, Voigt K, Beakes G (2010). Anaerobic fungi: Neocallimastigomycota. IAM Fungus, 1, 181-185. Author URL.
Maralikova B, Ali V, Nakada-Tsukui K, Nozaki T, van der Giezen M, Henze K, Tovar J (2010). Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria. Cell Microbiol, 12(3), 331-342. Abstract.  Author URL.  Full text.
van der Giezen, M (2009). Hydrogenosomes and Mitosomes: Conservation and Evolution of Functions. J EUKARYOT MICROBIOL, 56(3), 221-231. Abstract.
van Grinsven KWA, Rosnowsky S, van Weelden SWH, Puetz S, van der Giezen M, Martin W, van Hellemond JJ, Tielens AGM, Henze K (2008). Acetate : succinate CoA-transferase in the hydrogenosomes of Trichomonas vaginalis - Identification and characterization. JOURNAL OF BIOLOGICAL CHEMISTRY, 283(3), 1411-1418. Author URL.
Hamblin K, Standley DM, Rogers MB, Stechmann A, Roger AJ, Maytum R, van der Giezen M (2008). Localisation and nucleotide specificity of Blastocystis succinyl-CoA synthetase. Molecular Microbiology, 68, 1395-1405. Full text.
Stechmann A, Hamblin K, Pérez-Brocal V, Gaston D, Richmond GS, van der Giezen M, Clark CG, Roger AJ (2008). Organelles in Blastocystis that blur the distinction between mitochondria and hydrogenosomes. Curr Biol, 18(8), 580-585. Abstract.  Author URL.  Full text.
Puthiyaveetil S, Kavanagh TA, Cain P, Sullivan JA, Newall CA, Gray JC, Robinson C, van der Giezen M, Rogers MB, Allen JF, et al (2008). The ancestral symbiont sensor kinase CSK links photosynthesis with gene expression in chloroplasts. Proceedings of the National Academy of Sciences USA, 105, 10061-10066. Full text.
Tovar J, Cox SSE, van der Giezen M (2007). A mitosome purification protocol based on percoll density gradients and its use in validating the mitosomal nature of Entamoeba histolytica mitochondrial Hsp70. Methods Mol Biol, 390, 167-177. Abstract.  Author URL.
Van Der Giezen M (2007). Methods in Molecular Biology: Preface. Methods in Molecular Biology, 390
Cox SSE, van der Giezen M, Tarr SJ, Crompton MR, Tovar J (2006). Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis. BMC Microbiol, 6 Abstract.  Author URL.  Full text.
Richards TA, van der Giezen M (2006). Evolution of the Isd11-IscS complex reveals a single alpha-proteobacterial endosymbiosis for all eukaryotes. MOLECULAR BIOLOGY AND EVOLUTION, 23(7), 1341-1344. Author URL.
Dacks JB, Dyal PL, Embley TM, van der Giezen M (2006). Hydrogenosomal succinyl-CoA synthetase from the rumen-dwelling fungus Neocallimastix patriciarum; an energy-producing enzyme of mitochondrial origin. GENE, 373, 75-82. Author URL.
van der Giezen, M. (2006). Mitochondrial amazement. EMBO Reports, 7(478).
van der Giezen M (2006). Mitochondrial amazement. EMBO reports, 7(5), 478-478.
Chan KW, Slotboom DJ, Cox S, Embley TM, Fabre O, van der Giezen M, Harding M, Horner DS, Kunji ERS, Leon-Avila G, et al (2005). A novel ADP/ATP transporter in the mitosome of the microaerophilic human parasite Entamoeba histolytica. CURRENT BIOLOGY, 15(8), 737-742. Author URL.
Brinkmann H, van der Giezen M, Zhou Y, Poncelin de Raucourt G, Philippe H (2005). An empirical assessment of long-branch attraction artefacts in deep eukaryotic phylogenomics. Syst Biol, 54(5), 743-757. Abstract.  Author URL.
van der Giezen M, Leon-Avila G, Tovar J (2005). Characterization of chaperonin 10 (Cpn10) from the intestinal human pathogen Entamoeba histolytica. MICROBIOLOGY-SGM, 151, 3107-3115. Author URL.
van der Giezen M, Tovar J (2005). Degenerate mitochondria. EMBO REPORTS, 6(6), 525-530. Author URL.
van der Giezen M (2005). Endosymbiosis: past and present. HEREDITY, 95(5), 335-336. Author URL.
Van Der Giezen M (2005). Evolutionary biology. Endosymbiosis: Past and present. Heredity, 95(5), 335-336.
van der Giezen M, Tovar J, Clark CG (2005). Mitochondrion-derived organelles in protists and fungi. Int Rev Cytol, 244, 175-225. Abstract.  Author URL.
Regoes A, Zourmpanou D, León-Avila G, van der Giezen M, Tovar J, Hehl AB (2005). Protein import, replication, and inheritance of a vestigial mitochondrion. J Biol Chem, 280(34), 30557-30563. Abstract.  Author URL.
van der Giezen M, Cox S, Tovar J (2004). The iron-sulfur cluster assembly genes iscS and iscU of Entamoeba histolytica were acquired by horizontal gene transfer. BMC EVOLUTIONARY BIOLOGY, 4 Author URL.  Full text.
van der Giezen M, Birdsey GM, Horner DS, Lucocq J, Dyal PL, Benchimol M, Danpure CJ, Embley TM (2003). Fungal hydrogenosomes contain mitochondrial heat-shock proteins. MOLECULAR BIOLOGY AND EVOLUTION, 20(7), 1051-1061. Author URL.
Embley TM, van der Giezen M, Horner DS, Dyal PL, Bell S, Foster PG (2003). Hydrogenosomes, mitochondria and early eukaryotic evolution. IUBMB LIFE, 55(7), 387-395. Author URL.
Embley TM, van der Giezen M, Horner DS, Dyal PL, Foster P (2003). Mitochondria and hydrogenosomes are two forms of the same fundamental organelle. Philos Trans R Soc Lond B Biol Sci, 358(1429), 191-201. Abstract.  Author URL.
Tovar J, León-Avila G, Sánchez LB, Sutak R, Tachezy J, van der Giezen M, Hernández M, Müller M, Lucocq JM (2003). Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation. Nature, 426(6963), 172-176. Abstract.  Author URL.
Davidson EA, van der Giezen M, Horner DS, Embley TM, Howe CJ (2002). An [Fe] hydrogenase from the anaerobic hydrogenosome-containing fungus Neocallimastix frontalis L2. Gene, 296(1-2), 45-52. Abstract.  Author URL.
van der Giezen M, Slotboom DJ, Horner DS, Dyal PL, Harding M, Xue GP, Embley TM, Kunji ERS (2002). Conserved properties of hydrogenosomal and mitochondrial ADP/ATP carriers: a common origin for both organelles. EMBO JOURNAL, 21(4), 572-579. Author URL.
Van der Giezen M (2002). Strange fungi with even stranger insides. Mycologist, 16(3), 129-131.
van der Giezen M, Kiel JA, Sjollema KA, Prins RA (1998). The hydrogenosomal malic enzyme from the anaerobic fungus neocallimastix frontalis is targeted to mitochondria of the methylotrophic yeast hansenula polymorpha. Curr Genet, 33(2), 131-135. Abstract.  Author URL.
Van der Giezen M, Prins RA (1997). A common evolutionary origin for mitochondria and hydrogenosomes. Reproduction Nutrition Development, 37(SUPPL.).
van der Giezen M, Rechinger KB, Svendsen I, Durand R, Hirt RP, Fèvre M, Embley TM, Prins RA (1997). A mitochondrial-like targeting signal on the hydrogenosomal malic enzyme from the anaerobic fungus Neocallimastix frontalis: support for the hypothesis that hydrogenosomes are modified mitochondria. Mol Microbiol, 23(1), 11-21. Abstract.  Author URL.
Biagini GA, Van Der Giezen M, Hill B, Winters C, Lloyd D (1997). Ca<sup>2+</sup>accumulation in the hydrogenosomes of Neocallimastix frontalis L2: a mitochondrial-like physiological role. FEMS Microbiology Letters, 149(2), 227-232. Abstract.
van der Giezen M, Sjollema KA, Artz RR, Alkema W, Prins RA (1997). Hydrogenosomes in the anaerobic fungus Neocallimastix frontalis have a double membrane but lack an associated organelle genome. FEBS Lett, 408(2), 147-150. Abstract.  Author URL.
Gasc AM, Giammarinaro P, Ton-Hoang B, Geslin P, van der Giezen M, Sicard M (1997). Structural organization of the Streptococcus pneumoniae chromosome and relatedness of penicillin-sensitive and -resistant strains in type 9V. Microb Drug Resist, 3(1), 65-72. Abstract.  Author URL.
Brondijk THC, Durand R, van der Giezen M, Gottschal JC, Prins RA, Fèvre M (1996). scsB. MGG Molecular & General Genetics, 253(3), 315-315.
Brondijk TH, Durand R, van der Giezen M, Gottschal JC, Prins RA, Fèvre M (1996). scsB, a cDNA encoding the hydrogenosomal beta subunit of succinyl-CoA synthetase from the anaerobic fungus Neocallimastix frontalis. Mol Gen Genet, 253(3), 315-323. Abstract.  Author URL.

Chapters

van Aerle R, van der Giezen M (2017). Next-Generation Sequencing, Bioinformatics, and Infectious Diseases. In  (Ed) Genetics and Evolution of Infectious Diseases: Second Edition, 405-420.  Abstract.
de Paula WBM, Allen JF, van der Giezen M (2012). Mitochondria, Hydrogenosomes and Mitosomes in Relation to the CoRR Hypothesis for Genome Function and Evolution. In Bullerwell CE (Ed) Organelle Genetics, 105-122.
Paszkiewicz KH, van der Giezen M (2010). Omics, bioinformatics and infectious disease research. In Tibayrenc M (Ed) Genetics and Evolution of Infectious Disease, Elsevier, 523-539.  Abstract.
Tsaousis AD, Stechmann A, Hamblin KA, van der Giezen M, Pérez-Brocal V, Clark CG (2009). The Blastocystis mitochondrion-like organelles. In Clark CG, Johnson PJ, Adam RD (Eds.) Anaerobic parasitic protozoa: Genomics and molecular biology, Norwich: Caister Academic Press Ltd, 207-221.
Allen CA, van der Giezen M, Allen JF (2007). Origin, function, and transmission of mitochondria. In Martin W, Müller M (Eds.) Origin of mitochondria and hydrogenosomes, 39-56.
van der Giezen M, Tovar J (2004). Hydrogenosomes, mitosomes and mitochondria; variations on a theme?. In Horner DS, Hirt RP (Eds.) Organelles, genomes and eukaryote phylogeny: an evolutionary synthesis in the age of genomics, Organelles, genomes and eukaryote phylogeny: an evolutionary synthesis in the age of genomics. (Horner, D.S. and R.P. Hirt, Eds.): CRC Press Ltd, 283-302.
Cammack R, Horner DS, van der Giezen M, Kulda J, Lloyd D (2003). Iron-sulfur proteins in anaerobic eukaryotes. In: Biochemistry and physiology of anaerobic bacteria. In Ljungdahl L, Adams MWW, Barton LL, Ferry JG, Johnson MK (Eds.) Biochemistry and physiology of anaerobic bacteria, Biochemistry and physiology of anaerobic bacteria.: Springer, 113-127.
Gasc A, Giammarinaro P, Ton-Hoang B, Geslin P, van der Giezen M, Sicard M (2000). Structural organization of the Streptococcus pneumoniae chromosome and relatedness of penicillin-sensitive and -resistant strains in type 9V. In Tomasz A (Ed) Streptococcus pneumoniae, molecular biology and mechanisms of disease, Mary Ann Liebert, 25-32.
Prins RA, Marvin-Sikkema FD, van der Giezen M, Gottschal JC (1994). Hydrogenosomes of the anaerobic fungus Neocallimastix sp L2. In Prins RA, Stewart CS (Eds.) Micro-organisms in ruminant nutrition, Nottingham, UK: NOTTINGHAM UNIVERSITY PRESS, 179-194.
van der Giezen M, Gottschal JC, Prins RA (1994). The evolutionary origin of hydrogenosomes from anaerobic fungi. In Prins RA, Stewart CS (Eds.) Micro-organisms in ruminant nutrition, Nottingham, UK: NOTTINGHAM UNIVERSITY PRESS, 195-208.

Conferences

van DGM (2009). Eukaryotic life without mitochondria?. Annual Meeting of the Society-for-Experimental-Biology. 28th Jun - 1st Jul 2009.
Standley D, Kinjo A, Lis M, van der Giezen M, Nakamura H (2008). Structure-based functional annotation of protein sequences guided by comparative models. the Second International Symposium on Optimization and Systems Biology (OSB’08). 1st Oct 1931 - 1st Nov 2003.

Publications by year


2017

Vashisht K, Verma S, Gupta S, Lynn AM, Dixit R, Mishra N, Valecha N, Hamblin KA, Maytum R, Pandey KC, et al (2017). Engineering Nucleotide Specificity of Succinyl-CoA Synthetase in. Blastocystis : the Emerging Role of Gatekeeper Residues. Biochemistry, 56(3), 534-542. Full text.
Gentekaki E, Curtis BA, Stairs CW, Klimeš V, Eliáš M, Salas-Leiva DE, Herman EK, Eme L, Arias MC, Henrissat B, et al (2017). Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis. PLoS Biol, 15(9). Abstract.  Author URL.  Full text.
Herman E, Siegesmund MA, Bottery MJ, van Aerle R, Shather MM, Caler E, Dacks JB, van der Giezen M (2017). Membrane Trafficking Modulation during Entamoeba Encystation. SCIENTIFIC REPORTS, 7 Author URL.  Full text.
van Aerle R, van der Giezen M (2017). Next-Generation Sequencing, Bioinformatics, and Infectious Diseases. In  (Ed) Genetics and Evolution of Infectious Diseases: Second Edition, 405-420.  Abstract.

2016

van der Giezen M (2016). Evolution: Organelles Caught in the Act. Curr Biol, 26(20), R913-R915. Abstract.  Author URL.

2015

van der Giezen M (2015). Nature's Magic Algebra; or, How One Plus One Still Equaled One. BioScience, 65(8), 832-833.

2014

Stairs CW, Eme L, Brown MW, Mutsaers C, Susko E, Dellaire G, Soanes DM, Van Der Giezen M, Roger AJ (2014). A SUF Fe-S cluster biogenesis system in the mitochondrion-related organelles of the anaerobic protist Pygsuia. Current Biology, 24(11), 1176-1186. Abstract.
Bertolini C, van Aerle R, Lampis S, Moore KA, Paszkiewicz K, Butler CS, Vallini G, van der Giezen M (2014). Draft Genome Sequence of Stenotrophomonas maltophilia SeITE02, a Gammaproteobacterium Isolated from Selenite-Contaminated Mining Soil. Genome Announc, 2(3). Abstract.  Author URL.

2013

van der Giezen M (2013). Evolution: one thread to unite them all. Curr Biol, 23(16), R679-R681. Abstract.  Author URL.
Koumandou VL, Wickstead B, Ginger ML, van der Giezen M, Dacks JB, Field MC (2013). Molecular paleontology and complexity in the last eukaryotic common ancestor. Crit Rev Biochem Mol Biol, 48(4), 373-396. Abstract.  Author URL.
Read BA, Kegel J, Klute MJ, Kuo A, Lefebvre SC, Maumus F, Mayer C, Miller J, Monier A, Salamov A, et al (2013). Pan genome of the phytoplankton Emiliania underpins its global distribution. Nature, 499(7457), 209-213. Abstract.  Author URL.
Clark CG, van der Giezen M, Alfellani MA, Stensvold CR (2013). Recent developments in Blastocystis research. Adv Parasitol, 82, 1-32. Abstract.  Author URL.
Terali K, Beavil RL, Pickersgill RW, van der Giezen M (2013). The effect of the adaptor protein Isd11 on the quaternary structure of the eukaryotic cysteine desulphurase Nfs1. Biochem Biophys Res Commun, 440(2), 235-240. Abstract.  Author URL.

2012

Müller M, Mentel M, van Hellemond JJ, Henze K, Woehle C, Gould SB, Yu R-Y, van der Giezen M, Tielens AGM, Martin WF, et al (2012). Biochemistry and evolution of anaerobic energy metabolism in eukaryotes. Microbiol Mol Biol Rev, 76(2), 444-495. Abstract.  Author URL.
de Paula WBM, Allen JF, van der Giezen M (2012). Mitochondria, Hydrogenosomes and Mitosomes in Relation to the CoRR Hypothesis for Genome Function and Evolution. In Bullerwell CE (Ed) Organelle Genetics, 105-122.
Standley DM, van der Giezen M (2012). Modeling the alternative oxidase from the human pathogen Blastocystis using automated hybrid structural template assembly. Research and Reports in Biochemistry, 2, 1-8. Abstract.  Author URL.
van der Giezen M, Lenton TM (2012). The rise of oxygen and complex life. Journal of Eukaryotic Microbiology, 59(2), 111-113.

2011

van der Giezen M (2011). Mitochondria and the Rise of Eukaryotes. BIOSCIENCE, 61(8), 594-601. Author URL.
Siegesmund MA, Hehl AB, van der Giezen M (2011). Mitosomes in trophozoites and cysts of the reptilian parasite Entamoeba invadens. Eukaryot Cell, 10(11), 1582-1585. Abstract.  Author URL.
Herman EK, Walker G, van der Giezen M, Dacks JB (2011). Multivesicular bodies in the enigmatic amoeboflagellate Breviata anathema and the evolution of ESCRT 0. Journal of Cell Science, 124, 613-621. Abstract.

2010

Griffith GW, Baker S, Fliegerova K, Liggenstoffer A, van der Giezen M, Voigt K, Beakes G (2010). Anaerobic fungi: Neocallimastigomycota. IAM Fungus, 1, 181-185. Author URL.
Maralikova B, Ali V, Nakada-Tsukui K, Nozaki T, van der Giezen M, Henze K, Tovar J (2010). Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria. Cell Microbiol, 12(3), 331-342. Abstract.  Author URL.  Full text.
Paszkiewicz KH, van der Giezen M (2010). Omics, bioinformatics and infectious disease research. In Tibayrenc M (Ed) Genetics and Evolution of Infectious Disease, Elsevier, 523-539.  Abstract.

2009

van DGM (2009). Eukaryotic life without mitochondria?. Annual Meeting of the Society-for-Experimental-Biology. 28th Jun - 1st Jul 2009.
van der Giezen, M (2009). Hydrogenosomes and Mitosomes: Conservation and Evolution of Functions. J EUKARYOT MICROBIOL, 56(3), 221-231. Abstract.
Tsaousis AD, Stechmann A, Hamblin KA, van der Giezen M, Pérez-Brocal V, Clark CG (2009). The Blastocystis mitochondrion-like organelles. In Clark CG, Johnson PJ, Adam RD (Eds.) Anaerobic parasitic protozoa: Genomics and molecular biology, Norwich: Caister Academic Press Ltd, 207-221.

2008

van Grinsven KWA, Rosnowsky S, van Weelden SWH, Puetz S, van der Giezen M, Martin W, van Hellemond JJ, Tielens AGM, Henze K (2008). Acetate : succinate CoA-transferase in the hydrogenosomes of Trichomonas vaginalis - Identification and characterization. JOURNAL OF BIOLOGICAL CHEMISTRY, 283(3), 1411-1418. Author URL.
Hamblin K, Standley DM, Rogers MB, Stechmann A, Roger AJ, Maytum R, van der Giezen M (2008). Localisation and nucleotide specificity of Blastocystis succinyl-CoA synthetase. Molecular Microbiology, 68, 1395-1405. Full text.
Stechmann A, Hamblin K, Pérez-Brocal V, Gaston D, Richmond GS, van der Giezen M, Clark CG, Roger AJ (2008). Organelles in Blastocystis that blur the distinction between mitochondria and hydrogenosomes. Curr Biol, 18(8), 580-585. Abstract.  Author URL.  Full text.
Standley D, Kinjo A, Lis M, van der Giezen M, Nakamura H (2008). Structure-based functional annotation of protein sequences guided by comparative models. the Second International Symposium on Optimization and Systems Biology (OSB’08). 1st Oct 1931 - 1st Nov 2003.
Puthiyaveetil S, Kavanagh TA, Cain P, Sullivan JA, Newall CA, Gray JC, Robinson C, van der Giezen M, Rogers MB, Allen JF, et al (2008). The ancestral symbiont sensor kinase CSK links photosynthesis with gene expression in chloroplasts. Proceedings of the National Academy of Sciences USA, 105, 10061-10066. Full text.

2007

Tovar J, Cox SSE, van der Giezen M (2007). A mitosome purification protocol based on percoll density gradients and its use in validating the mitosomal nature of Entamoeba histolytica mitochondrial Hsp70. Methods Mol Biol, 390, 167-177. Abstract.  Author URL.
Van Der Giezen M (2007). Methods in Molecular Biology: Preface. Methods in Molecular Biology, 390
Allen CA, van der Giezen M, Allen JF (2007). Origin, function, and transmission of mitochondria. In Martin W, Müller M (Eds.) Origin of mitochondria and hydrogenosomes, 39-56.
van der Giezen, M. (2007). Protein targeting protocols., Humana Press Inc.

2006

Cox SSE, van der Giezen M, Tarr SJ, Crompton MR, Tovar J (2006). Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis. BMC Microbiol, 6 Abstract.  Author URL.  Full text.
Richards TA, van der Giezen M (2006). Evolution of the Isd11-IscS complex reveals a single alpha-proteobacterial endosymbiosis for all eukaryotes. MOLECULAR BIOLOGY AND EVOLUTION, 23(7), 1341-1344. Author URL.
Dacks JB, Dyal PL, Embley TM, van der Giezen M (2006). Hydrogenosomal succinyl-CoA synthetase from the rumen-dwelling fungus Neocallimastix patriciarum; an energy-producing enzyme of mitochondrial origin. GENE, 373, 75-82. Author URL.
van der Giezen, M. (2006). Mitochondrial amazement. EMBO Reports, 7(478).
van der Giezen M (2006). Mitochondrial amazement. EMBO reports, 7(5), 478-478.

2005

Chan KW, Slotboom DJ, Cox S, Embley TM, Fabre O, van der Giezen M, Harding M, Horner DS, Kunji ERS, Leon-Avila G, et al (2005). A novel ADP/ATP transporter in the mitosome of the microaerophilic human parasite Entamoeba histolytica. CURRENT BIOLOGY, 15(8), 737-742. Author URL.
Brinkmann H, van der Giezen M, Zhou Y, Poncelin de Raucourt G, Philippe H (2005). An empirical assessment of long-branch attraction artefacts in deep eukaryotic phylogenomics. Syst Biol, 54(5), 743-757. Abstract.  Author URL.
van der Giezen M, Leon-Avila G, Tovar J (2005). Characterization of chaperonin 10 (Cpn10) from the intestinal human pathogen Entamoeba histolytica. MICROBIOLOGY-SGM, 151, 3107-3115. Author URL.
van der Giezen M, Tovar J (2005). Degenerate mitochondria. EMBO REPORTS, 6(6), 525-530. Author URL.
van der Giezen M (2005). Endosymbiosis: past and present. HEREDITY, 95(5), 335-336. Author URL.
Van Der Giezen M (2005). Evolutionary biology. Endosymbiosis: Past and present. Heredity, 95(5), 335-336.
van der Giezen M, Tovar J, Clark CG (2005). Mitochondrion-derived organelles in protists and fungi. Int Rev Cytol, 244, 175-225. Abstract.  Author URL.
Regoes A, Zourmpanou D, León-Avila G, van der Giezen M, Tovar J, Hehl AB (2005). Protein import, replication, and inheritance of a vestigial mitochondrion. J Biol Chem, 280(34), 30557-30563. Abstract.  Author URL.

2004

van der Giezen M, Tovar J (2004). Hydrogenosomes, mitosomes and mitochondria; variations on a theme?. In Horner DS, Hirt RP (Eds.) Organelles, genomes and eukaryote phylogeny: an evolutionary synthesis in the age of genomics, Organelles, genomes and eukaryote phylogeny: an evolutionary synthesis in the age of genomics. (Horner, D.S. and R.P. Hirt, Eds.): CRC Press Ltd, 283-302.
van der Giezen M, Cox S, Tovar J (2004). The iron-sulfur cluster assembly genes iscS and iscU of Entamoeba histolytica were acquired by horizontal gene transfer. BMC EVOLUTIONARY BIOLOGY, 4 Author URL.  Full text.

2003

van der Giezen M, Birdsey GM, Horner DS, Lucocq J, Dyal PL, Benchimol M, Danpure CJ, Embley TM (2003). Fungal hydrogenosomes contain mitochondrial heat-shock proteins. MOLECULAR BIOLOGY AND EVOLUTION, 20(7), 1051-1061. Author URL.
Embley TM, van der Giezen M, Horner DS, Dyal PL, Bell S, Foster PG (2003). Hydrogenosomes, mitochondria and early eukaryotic evolution. IUBMB LIFE, 55(7), 387-395. Author URL.
Cammack R, Horner DS, van der Giezen M, Kulda J, Lloyd D (2003). Iron-sulfur proteins in anaerobic eukaryotes. In: Biochemistry and physiology of anaerobic bacteria. In Ljungdahl L, Adams MWW, Barton LL, Ferry JG, Johnson MK (Eds.) Biochemistry and physiology of anaerobic bacteria, Biochemistry and physiology of anaerobic bacteria.: Springer, 113-127.
Embley TM, van der Giezen M, Horner DS, Dyal PL, Foster P (2003). Mitochondria and hydrogenosomes are two forms of the same fundamental organelle. Philos Trans R Soc Lond B Biol Sci, 358(1429), 191-201. Abstract.  Author URL.
Tovar J, León-Avila G, Sánchez LB, Sutak R, Tachezy J, van der Giezen M, Hernández M, Müller M, Lucocq JM (2003). Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation. Nature, 426(6963), 172-176. Abstract.  Author URL.

2002

Davidson EA, van der Giezen M, Horner DS, Embley TM, Howe CJ (2002). An [Fe] hydrogenase from the anaerobic hydrogenosome-containing fungus Neocallimastix frontalis L2. Gene, 296(1-2), 45-52. Abstract.  Author URL.
van der Giezen M, Slotboom DJ, Horner DS, Dyal PL, Harding M, Xue GP, Embley TM, Kunji ERS (2002). Conserved properties of hydrogenosomal and mitochondrial ADP/ATP carriers: a common origin for both organelles. EMBO JOURNAL, 21(4), 572-579. Author URL.
Van der Giezen M (2002). Strange fungi with even stranger insides. Mycologist, 16(3), 129-131.

2000

Gasc A, Giammarinaro P, Ton-Hoang B, Geslin P, van der Giezen M, Sicard M (2000). Structural organization of the Streptococcus pneumoniae chromosome and relatedness of penicillin-sensitive and -resistant strains in type 9V. In Tomasz A (Ed) Streptococcus pneumoniae, molecular biology and mechanisms of disease, Mary Ann Liebert, 25-32.

1998

van der Giezen M, Kiel JA, Sjollema KA, Prins RA (1998). The hydrogenosomal malic enzyme from the anaerobic fungus neocallimastix frontalis is targeted to mitochondria of the methylotrophic yeast hansenula polymorpha. Curr Genet, 33(2), 131-135. Abstract.  Author URL.

1997

Van der Giezen M, Prins RA (1997). A common evolutionary origin for mitochondria and hydrogenosomes. Reproduction Nutrition Development, 37(SUPPL.).
van der Giezen M, Rechinger KB, Svendsen I, Durand R, Hirt RP, Fèvre M, Embley TM, Prins RA (1997). A mitochondrial-like targeting signal on the hydrogenosomal malic enzyme from the anaerobic fungus Neocallimastix frontalis: support for the hypothesis that hydrogenosomes are modified mitochondria. Mol Microbiol, 23(1), 11-21. Abstract.  Author URL.
Biagini GA, Van Der Giezen M, Hill B, Winters C, Lloyd D (1997). Ca<sup>2+</sup>accumulation in the hydrogenosomes of Neocallimastix frontalis L2: a mitochondrial-like physiological role. FEMS Microbiology Letters, 149(2), 227-232. Abstract.
van der Giezen M, Sjollema KA, Artz RR, Alkema W, Prins RA (1997). Hydrogenosomes in the anaerobic fungus Neocallimastix frontalis have a double membrane but lack an associated organelle genome. FEBS Lett, 408(2), 147-150. Abstract.  Author URL.
Gasc AM, Giammarinaro P, Ton-Hoang B, Geslin P, van der Giezen M, Sicard M (1997). Structural organization of the Streptococcus pneumoniae chromosome and relatedness of penicillin-sensitive and -resistant strains in type 9V. Microb Drug Resist, 3(1), 65-72. Abstract.  Author URL.

1996

Brondijk THC, Durand R, van der Giezen M, Gottschal JC, Prins RA, Fèvre M (1996). scsB. MGG Molecular & General Genetics, 253(3), 315-315.
Brondijk TH, Durand R, van der Giezen M, Gottschal JC, Prins RA, Fèvre M (1996). scsB, a cDNA encoding the hydrogenosomal beta subunit of succinyl-CoA synthetase from the anaerobic fungus Neocallimastix frontalis. Mol Gen Genet, 253(3), 315-323. Abstract.  Author URL.

1994

Prins RA, Marvin-Sikkema FD, van der Giezen M, Gottschal JC (1994). Hydrogenosomes of the anaerobic fungus Neocallimastix sp L2. In Prins RA, Stewart CS (Eds.) Micro-organisms in ruminant nutrition, Nottingham, UK: NOTTINGHAM UNIVERSITY PRESS, 179-194.
van der Giezen M, Gottschal JC, Prins RA (1994). The evolutionary origin of hydrogenosomes from anaerobic fungi. In Prins RA, Stewart CS (Eds.) Micro-organisms in ruminant nutrition, Nottingham, UK: NOTTINGHAM UNIVERSITY PRESS, 195-208.

mark_van_der_giezen Details from cache as at 2018-02-24 19:44:07

Awards/Honorary fellowships

2014 Fellow of the Linnean Society.

1997 Fellow of the European Molecular Biology Organisation (EMBO).


Committee/panel activities

2013-present Advanced Degree Accreditation Assessor for the Royal Society of Biology.

2012 Nominated for President for the International Society of Protistologists (ISOP)

2012-2013 Director for the Primary Academies Trust.

2012-2013 Member of the Strategic Governors Committee for the First Federation, Devon.

2011-present Member of the Natural Environment Research Council (NERC) Peer Review College

2010-present Member of the Board of Reviewers for the Journal of Eukaryotic Microbiology

2007-2009 Member of the grant-awarding CoSyst panel of the Biotechnology and Biological Sciences Research Council (BBRSC)

2006-2007 Member of the Steering Group for the PGCAP (Post Graduate Certificate in Academic Practice) and CILT (Certificate in Learning and Teaching) at Queen Mary, University of London

2006 and 2007 Member of the grant-awarding Systematics Research Fund panel of the Systematics Association and the Linnean Society

2005-2007 and 2009-2010 Member of the Council of the Systematics Association

1994-1996 Elected Member of Council of the University of Groningen, The Netherlands

1994-1996 Member of the Council Committee for Student Affairs of the University of Groningen, The Netherlands

1994-1995 Member of the University Committee for Student Affairs of the University of Groningen, The Netherlands


Editorial responsibilities

Ad hoc referee for international peer-reviewed scientific journals (Advances in Parasitology, Biochimica et Biophysica Acta, BioScience, BMC Evolutionary Biology; BMC Systems Biology, Current Biology, Eukaryotic Cell, Experimental Parasitology, FEBS Journal, Freshwater Biology, Folia Parasitologica, Genome Biology and Evolution, International Journal for Parasitology, Journal of Eukaryotic Microbiology, Journal of Experimental Botany, Journal of Molecular Biology, Journal of Parasitology Research, Microbiology, Mitochondrion, Molecular Biology and Evolution, Philosophical Transactions of the Royal Society London, PLoS Neglected Tropical Diseases, PLoS Pathogens, Protist, Science, Tissue & Cell).


Invited lectures

December 14-15, 2017 Shaping eukaryotic evolution via mitochondrial symbiosis. Invited speaker at the Templeton Foundation Workshop on Deep Evolutionary Biology, University of Manchester.

October 4, 2017 Biochemical and evolutionary peculiarities of the hyper-prevalent parasitic eukaryote Blastocystis. Invited by Prof. John Allen, The Department of Genetics, Evolution and Environment, University College London.

May 16, 2017 Two genome projects: one because we’re curious, the other because we need better diagnostics. Invited speaker at the USF Genomics Symposium, University of South Florida, Tampa, USA.

May 15, 2017 Biochemical peculiarities of the hyper-prevalent parasitic eukaryote Blastocystis. Invited speaker at the CGHIDR-CDDI Annual Symposium on Frontiers of Drug Discovery and Infectious Diseases, University of South Florida, Tampa, USA.

March 29 - April 2, 2017 Mitochondrial glycolysis in stramenopiles. Invited speaker at the 115th International Titisee Conference on “Evolutionary mitochondrial biology: molecular, biochemical, and metabolic diversity”, Titisee, Black Forest, Germany.

March 30 – April 2, 2015 Mitochondria and related organelles in microbial eukaryotes. Invited symposium presentation at the Society for General Microbiology (SGM) Annual Meeting, Birmingham, UK.

June 16, 2014 Mitochondria but not as you know them. Invited by Dr. Anastasios Tsaousis, School of Biosciences, University of Kent.

April 18, 2013 Unusual biochemistry and cell biology of the intestinal parasite Blastocystis. Invited by Dr. Graham Clark, London School of Hygiene and Tropical Medicine.

November 23, 2011 Can unusual mitochondria of the anaerobic human parasite Blastocystis change our textbooks? Invited by Professor John Moody, School of Biomedical and Biological Sciences, University of Plymouth.

October 27, 2011 Weird mitochondria as proxies for understanding eukaryotic evolution. Invited by Professor David Lloyd, School of Biosciences, Cardiff University.

September 21-23, 2011 Hydrogenosomes and mitosomes as proxies for understanding eukaryotic evolution. Invited symposium speaker at the 2nd Student-organized International Symposium of the DFG Research Training Group 1216 ‘Intra - and Intercellular Transport and Communication’, Marburg, Germany.

July 25-29, 2011 Molecular oxygen and intelligent life. Invited speaker at the workshop: Using the diversity of Protists to educate students and the public about evolution. VI European Congress of Protistology, Berlin, Germany.

April 13-14, 2011 The anaerobic human parasite Blastocystis, a non-conforming eukaryote. Invited by Professor William Martin, Institut für Botanik III, Heinrich-Heine Universität Düsseldorf, Germany.

September 9, 2010 The anaerobic intestinal parasite Blastocystis, another non-conforming eukaryote. Invited by Professor Jan Tachezy at the Department of Parasitology, Charles University, Prague, Czech Republic.

August 1-6, 2010 Adaptations to an anaerobic niche: hydrogenosomes in the Neocallimastigomycota. Invited presentation at the 9th International Mycological Congress, Edinburgh, UK.

July 18-23, 2010 Anaerobic mitochondria; from irrelevant oddities to relevant entities. Invited presentation at the joint International Society of Protistologists/British Society for Protist Biology Meeting, University of Kent, Canterbury, UK.

May 6, 2010 An unusual nitric oxide synthase from the human parasite Trichomonas vaginalis. Iron-Sulfur Proteins Discussion Group Meeting; MRC National Institute for Medical Research (Mill Hill).

21-22 September 2009 Piecing together the Emiliania huxleyi mitochondrial proteome and its evolutionary ancestry. Invited presentation for the Leverhulme Emiliania huxleyi international collaboration grant, University of Essex, Colchester, UK.

7-10 September 2009 Grafting mitochondria onto the tree of life. Invited symposium presentation at the Society for General Microbiology (SGM) Autumn Meeting, Edinburgh, UK.

16 September 2009 An unusual nitric oxide synthase from the human parasite Trichomonas vaginalis. Invited seminar for the Peninsula Oxidative Stress Research Forum (POSReF), Lavender House Hotel, Ashburton, UK.

28 June -1 July 2009 Eukaryotic life without mitochondria? Invited symposium presentation at the Society for Experimental Biology Annual Main Meeting, Glasgow, UK.

17-19 June 2009 Bioinformatics reconstruction of the Emiliania huxleyi mitochondrial proteome and its evolutionary ancestry. Presentation at the Emiliania huxleyi Genome Jamboree, Woods Hole, USA.

14 April 2009 Human parasites and their impact on understanding mitochondrial evolution. Invited by Prof. Jan Kok at the Department of Molecular Genetics of the University of Groningen, the Netherlands.

16 March 2009 Human parasites and their impact on understanding mitochondrial evolution. Invited by Prof. Colin Robinson at the Department of Biological Sciences of the University of Warwick, UK.

22 January 2009 At the interface between biochemistry and evolution. Invited by Prof. Haruki Nakamura at the Institute for Protein Research, Osaka University and the Protein Database Japan, Japan.

21-26 July 2008 Hydrogenosomes and mitosomes of anaerobic protists. Invited Symposium speaker at Protist 2008, Halifax, Canada

12 July 2007 Mitochondria, but not as you know them; unusual anaerobic mitochondria from human parasites. Invited by Prof. Thomas Langer at the Insititute of Genetics, University of Cologne, Germany

5 April 2007 Mitochondria, but not as you know them; unusual anaerobic mitochondria from human parasites. Invited by Dr Guy Hanke at the Institute for Protein Research, University of Osaka, Japan

1-5 August 2006 Hydrogenosomes and mitosomes; mitochondria on their way out? Invited presentation at the 16th International Society for Evolutionary Protistology (ISEP), Wroclaw, Poland

21 April 2006 Evolution of the Isd11/IscS complex reveals a single α-proteobacterial endosymbiosis for all eukaryotes. Iron-Sulfur Proteins Discussion Group Meeting; King's College, London, UK.

Feb 2006 Mitosomes are mitochondria. Presentation at the Max Planck Institute for Terrestrial Micorobiology, Marburg, Germany

Nov 2005 Degenerate mitochondria; convergent adaptations to an anaerobic lifestyle. Presentation at 'Evolutionary inferences from phylogenetic trees', a workshop sponsored by the Centre for Ecology and Evolution, London, UK.

5-8 Oct 2005 Why mitochondria are never lost. Presentation at the 'International Symposium; 100 years of the endosymbiotic theory: from prokaryotes to eukaryotic organelles'. Hamburg, Germany

13 April 2005 Mitochondrial energy production in anaerobic microbial eukaryotes. Presentation at 'Energy conversion in the origins and evolution of cells'. Queen Mary, Univeristy of London, UK

June 2004 Early eukaryotes and mitochondrial remnants. Invited by Dr Salvador Carranza; seminar for the Genetics Department, University of Barcelona, Spain.

May 2004 Degenerate mitochondria and early branching eukaryotes. Invited by Dr Kirill Degtyarenko; seminar for the European Bioinformatics Institute, Hinxton, UK.

May 2004 Mitochondrial remnants and early eukaryotic evolution. Invited by Prof. David Fell; talk for the Cell Systems Modelling Group, Oxford Brookes University, UK.

23 April 2004 FeS protein assembly in early eukaryotes. Iron-Sulfur Proteins Discussion Group Meeting; King's College, London, UK.

Dec 2003 Hydrogenosomes, mitochondria and early eukaryotic evolution. Invited by Prof. Roland Lill; seminar for the Department of Cell Biology, Phillips University of Marburg and Department of Microbiology from the Max Planck institute, Germany.

Sept 2003 Hydrogenosomes, mitochondria and early eukaryotic evolution. Invited by Prof. John Samuelson; seminar for the Department of Molecular Cell Biology at the University of Boston, USA.

14-18 Sep 2003 Iron sulphur proteins IscU and IscS from the amitochondriate human parasite Entamoeba histolytica. Molecular Parasitology Meeting XIV. Marine Biological Laboratory, Woods Hole, MA, USA.

Oct 2001 Hydrogenosomes; specialised mitochondria? Invited by Prof. Tony Trinci; seminar for the School of Biological Sciences, University of Manchester, UK.

June 2001 Hydrogenosomes are modified mitochondria. EMBO Fellows Meeting, EMBO, Heidelberg, Germany.

Feb 2001 Hydrogenosomes. Invited by Dr Colin Stewart; seminar for the Rowett Research Institute, Aberdeen, Scotland, UK.

Discussing the write-up of a paper.

Year 3

  • BIO3093 Energy Metabolism

MSc

  • BIOM509 Professional Skills
  • BIOM562 Sustainable Land Use in Grassland Agriculture
  • BIOM566 Sustainable Livestock and Fisheries

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