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Dr Arnab Pradhan

Dr Arnab Pradhan

Postdoctoral Research Associate in Medical Mycology

 Geoffrey Pope 328

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

 Office hours:

9am-5pm

Overview

I am originally from India. I moved to United Kingdom to study MRes in Biomedical Sciences at the University of Glasgow. Upon completion, I started PhD in Medical Sciences at MRC Centre for Medical Mycology, University of Aberdeen under the supervision of Prof. Alistair J.P. Brown. I defended my PhD in February, 2019 and started as a Postdoctoral Research Associate in Medical Mycology in April at the University of Exeter. However, I was working in Prof. Alistair Brown’s lab at MRC Centre for Medical Mycology, University of Aberdeen after receiving an honorary Post-doctorate status. I finally moved to Exeter and started my job at the College of Life and Environmental Sciences, University of Exeter from September, 2019.

My main area of research is focused on Medical Mycology, investigating mechanisms of Candida albicans adaptation to host niches and immune response.

Qualifications

  • PhD in Medical Sciences (MRC Centre for Medical Mycology, University of Aberdeen, UK)
  • MRes in Biomedical Sciences (Medical Biochemistry and Molecular Biology) (University of Glasgow, UK)
  • MSc in Biochemistry (Bangalore University, India)
  • BSc in Genetics, Molecular Biology, Biotechnology (Bangalore University, India)

Links

Research

Research interests

Understanding stress adaptation and impact of fungal adaptation upon host recognition and pathogenesis.

Research projects

Current Project:

Understanding the impact of fungal adaptation upon host recognition and pathogenesis in Candida albicans

Grants/Funding:

MRC Centre for Medical Mycology

 

Links


Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Brown A, Pradhan A, Larcombe D, Gow N (In Press). Epitope shaving promotes fungal immune evasion. mBio Full text.
Pradhan A, Ma Q, de Assis LJ, Leaves I, Larcombe DE, Rodriguez Rondon AV, Nev OA, Brown AJP (2021). Anticipatory Stress Responses and Immune Evasion in Fungal Pathogens. Trends in Microbiology, 29(5), 416-427. Abstract.  Full text.
Bain JM, Alonso MF, Childers DS, Walls CA, Mackenzie K, Pradhan A, Lewis LE, Louw J, Avelar GM, Larcombe DE, et al (2021). Immune cells fold and damage fungal hyphae. Proc Natl Acad Sci U S A, 118(15). Abstract.  Author URL.  Full text.
Hatinguais R, Pradhan A, Brown GD, Brown AJP, Warris A, Shekhova E (2021). Mitochondrial Reactive Oxygen Species Regulate Immune Responses of Macrophages to Aspergillus fumigatus. Front Immunol, 12 Abstract.  Author URL.  Full text.
Childers DS, Avelar GM, Bain JM, Larcombe DE, Pradhan A, Budge S, Heaney H, Brown AJP (2020). Impact of the Environment upon the Candida albicans Cell Wall and Resultant Effects upon Immune Surveillance. Curr Top Microbiol Immunol, 425, 297-330. Abstract.  Author URL.
Brown AJP, Larcombe DE, Pradhan A (2020). Thoughts on the evolution of Core Environmental Responses in yeasts. Fungal Biology, 124(5), 475-481. Full text.
Pradhan A, Avelar GM, Bain JM, Childers D, Pelletier C, Larcombe DE, Shekhova E, Netea MG, Brown GD, Erwig L, et al (2019). Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion. Nat Commun, 10(1). Abstract.  Author URL.  Full text.
Pradhan A, Avelar GM, Bain JM, Childers DS, Larcombe DE, Netea MG, Shekhova E, Munro CA, Brown GD, Erwig LP, et al (2018). Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase a Signaling. mBio, 9(6). Abstract.  Author URL.
Pradhan A, Herrero-de-Dios C, Belmonte R, Budge S, Lopez Garcia A, Kolmogorova A, Lee KK, Martin BD, Ribeiro A, Bebes A, et al (2017). Elevated catalase expression in a fungal pathogen is a double-edged sword of iron. PLoS Pathog, 13(5). Abstract.  Author URL.

Conferences

Childers DS, Avelar GM, Bain J, Pradhan A, Larcome D, Netea M, Erwig L, Gow NAR, Brown AJP (2018). Fungal Transformers: Tracking a Moving Target.  Author URL.

Publications by year


In Press

Brown A, Pradhan A, Larcombe D, Gow N (In Press). Epitope shaving promotes fungal immune evasion. mBio Full text.

2021

Pradhan A, Ma Q, de Assis LJ, Leaves I, Larcombe DE, Rodriguez Rondon AV, Nev OA, Brown AJP (2021). Anticipatory Stress Responses and Immune Evasion in Fungal Pathogens. Trends in Microbiology, 29(5), 416-427. Abstract.  Full text.
Bain JM, Alonso MF, Childers DS, Walls CA, Mackenzie K, Pradhan A, Lewis LE, Louw J, Avelar GM, Larcombe DE, et al (2021). Immune cells fold and damage fungal hyphae. Proc Natl Acad Sci U S A, 118(15). Abstract.  Author URL.  Full text.
Hatinguais R, Pradhan A, Brown GD, Brown AJP, Warris A, Shekhova E (2021). Mitochondrial Reactive Oxygen Species Regulate Immune Responses of Macrophages to Aspergillus fumigatus. Front Immunol, 12 Abstract.  Author URL.  Full text.

2020

Childers DS, Avelar GM, Bain JM, Larcombe DE, Pradhan A, Budge S, Heaney H, Brown AJP (2020). Impact of the Environment upon the Candida albicans Cell Wall and Resultant Effects upon Immune Surveillance. Curr Top Microbiol Immunol, 425, 297-330. Abstract.  Author URL.
Brown AJP, Larcombe DE, Pradhan A (2020). Thoughts on the evolution of Core Environmental Responses in yeasts. Fungal Biology, 124(5), 475-481. Full text.

2019

Pradhan A, Avelar GM, Bain JM, Childers D, Pelletier C, Larcombe DE, Shekhova E, Netea MG, Brown GD, Erwig L, et al (2019). Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion. Nat Commun, 10(1). Abstract.  Author URL.  Full text.

2018

Childers DS, Avelar GM, Bain J, Pradhan A, Larcome D, Netea M, Erwig L, Gow NAR, Brown AJP (2018). Fungal Transformers: Tracking a Moving Target.  Author URL.
Pradhan A, Avelar GM, Bain JM, Childers DS, Larcombe DE, Netea MG, Shekhova E, Munro CA, Brown GD, Erwig LP, et al (2018). Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase a Signaling. mBio, 9(6). Abstract.  Author URL.

2017

Pradhan A, Herrero-de-Dios C, Belmonte R, Budge S, Lopez Garcia A, Kolmogorova A, Lee KK, Martin BD, Ribeiro A, Bebes A, et al (2017). Elevated catalase expression in a fungal pathogen is a double-edged sword of iron. PLoS Pathog, 13(5). Abstract.  Author URL.

Arnab_Pradhan Details from cache as at 2022-07-01 02:33:39

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