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Faculty of Health and Life Sciences

Dr Corin Liddle

Dr Corin Liddle

Experimental Officer for Light Microscopy

 C.C.Liddle@exeter.ac.uk

 2053

 Geoffrey Pope 115

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK


Overview

After obtaining a degree in Environmental Biology at Plymouth University, I worked as a research assistant at the Ecotoxicology Research & Innovation Centre (ERIC; part of Professor Richard Handy's lab), Plymouth University, where I developed my use of basic microscopy while imaging zebrafish.

Subsequently, I undertook my PhD research (within Professor Teresa Fernandes's and Professor Theodore B Henry's labs) at Heriot-Watt University, Edinburgh, where I studied the fate and bioavailability of silver nanomaterials within freshwater systems (AgNM).

 Then I worked as a research fellow at Exeter University (within Professor Tamara Galloway's and Professor Charles Tyler's labs), where I led research investigating the interaction and transfer of nanoplastics within a simple food web. During this project, I extensively applied fluorescence and confocal imaging, image quantitation and processing techniques.

Since February 2020, I have led the light microscopy applications within Exeter's Bioimaging Centre. Over the last few years, my responsibilities have expanded within Exeter's Bioimaging Centre. I now also lead Bioimagings light microscopy teaching responsibilities and lead the facility's developments in advanced light microscopy modalities, such as Structured illumination microscopy (SIM), fluorescence lifetime imaging (FLIM & FLIM-FRET), and fluorescence correlation microscopy (FCS & FCCS), single-molecule localisation microscopy (SMLM; dSTORM, DNA-PAINT and PALM), photostimulation and ablation and lightsheet and two-photon applications. 

Qualifications

2013-2016: Doctor of Philosophy (Ph.D.) Ecotoxicology - exposure and bioavailability assessment within freshwater environments. Heriot-Watt University, Edinburgh 

2014-2015: Learning Enhancement and Development Skills programme (LEADS); programme aligned with the UK Professional Standards Framework for Higher Education - HE Teacher, Tutor and Marker qualification. Center for Academic Leadership and Development. Heriot-Watt University.

2009-2012: Bachelor of Science (BSc) Hons Environmental Biology/Marine Biology. University of Plymouth

2005-2006: Foundation in Natural Science - Animal Physiology, Chemistry, Geology and Climate Change. Liverpool John Moores University

Career

February 2020 - Present: Experimental Officer for Light Microscopy. University of Exeter

April 2016 - October 2018: Research Fellow. University of Exeter

2012-2013: Research Assistant. University of Plymouth

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Research

Research interests

My academic background is in Nano-Ecotoxicology. I previously worked with Zebrafish and Stickleback fish as a model for over five years. My work was mainly done in academic research facilities, primarily at Plymouth University (2012), then Heriot-Watt University (2013-2016) and Exeter University (2016-2019).  

Historically my research experience  focused on the exposure and bioavailability of silver nanomaterials (AgNM) in freshwater environments (AgNM). More recently, at Exeter, I led research that addressed the interaction and transfer of nanoplastics within a simple freshwater food web. During my research posts, I have extensively applied wide-field fluorescence and confocal imaging, image quantitation and processing and analysis techniques. Since February 2020, I have been leading the support of the light microscopy applications of Exeter’s Bioimaging Centre. 

Research projects

Currently, I have ongoing collaborations with (among others) :

  • Anish Dattani & Ge Guo 
  • Vanessa Francis & Carolina Coelho 
  • Leandro De Assis, Iean Leaves & Alistair Brown
  • Sally Rogers & Lucy Brunt &Tom Piers & Steffen Scholpp
  • Miranda Smallwood & Alex Ferecsko & Paul Eggleton 
  • Aya Takesono & Charles Tyler
  • Vicky Gold 

This is just to list a few - always looking for new collaborations if my expertise are requested/needed on a project - Happy to discuss. 

Research networks

Biosciences 

Life Science Institute 

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Teaching

I am interested in finding effective ways to teach advanced light microscopy methods:

Fluorescence Microscopy (FM)

Fluorescence lifetime imaging (FLIM)

Fluorescence correlation microscopy (FCS)

Confocal Scanning Laser Microscopy (CSLM)

Single Molecule Localisation Microscopy (SMLM)

Module lead:

  • BIOM555 Bioimaging

 Co-lead for:

  • BIOM549 - Advanced Laboratory Skills

 Contributes to:

  • BIO2099 - Molecular Plant Science (Confocal workshop)

Modules

2023/24


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Office Hours:

8:30-5:00 Monday-Friday FT

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