Dr Fabian Salazar
Postdoctoral Research Fellow
Geoffrey Pope 328
Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK
PhD in Immunology, University of Nottingham, UK, 2016
MSc in Biochemistry, major in Proteins and Biotechnology, University of Chile, 2010
Biochemistry (Professional Degree), University of Chile, 2010
BSc in Biochemistry, University of Chile, 2008
Postdoctoral Research Fellow, University of Aberdeen, 2016-2019
The immune system utilizes sensors on immune cells named pattern recognition receptors to recognize invading pathogens and foreign substances. These receptors trigger a plethora of immune responses that confer protection against infection and could also contribute to unwanted exacerbated immune responses.
In the Brown Group, we are interested in a superfamily of receptors called C-type lectin receptors (CLRs). The prototypic member of this family, Dectin-1, identified by Prof. Gordon Brown, plays a central role in mounting a protective innate immune response against fungal infections. However, we know very little of how these receptors, in particular Dectin-1, influences adaptive immune responses to fungi.
We have recently identified a novel family of CLRs and my research is aimed at better understanding the roles and functions of these receptors and how they influence innate and adaptive immunity during fungal infection.
Role of CLRs in innate and adaptive immunity to fungi