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Dr Harley Worthy

Research Associate

 Biocatalysis Centre BC1.2

 

Biocatalysis Centre, University of Exeter, The Henry Wellcome Building for Biocatalysis, Stocker Road, Exeter, EX4 4QD , UK

 Office hours:

Monday – Friday 9 am – 5 pm

Overview

After graduating from Cardiff University with a B.Sc. Biochemistry I joined the lab of Dr Dafydd Jones for my Doctoral training. There I focussed on incorporating non-canonical amino acids (ncAAs) into proteins and studying the structural and functional changes of these mutations. I also studied how these mutations could be used to generate artificial protein oligomers and interface with nano materials and surfaces (DNA origami tiles and carbon nanotubes).

Currently, I am working in the lab of Prof, Littlechild in the Biocatalysis centre at University of Exeter, in conjunction with Unilever. My major focus on generating cold adaptive enzymes, for use in environmentally friendly biological washing formulations.

During my PhD and subsequent Post-doc positions in the Jones and Littlechild groups, I have developed expertise in multiple techniques including:

  • Cloning and DNA manipulation
  • Recombinant protein expression and purification
  • X-ray crystallography
  • Fluorescence/Absorbance spectroscopy
  • SEC-DLS
  • Protein modelling and molecular dynamics

Qualifications

PhD Biochemistry - Cardiff University (2014-2018)

B.Sc. (Hons) Biochemistry - Cardiff University (2010-2014)

Career

Post Doctoral Research Associate, University of Exeter (05/2019- Present)

Research Associate, Cardiff University (02/2018-05/2019)

 

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