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Dr Jane Usher

Dr Jane Usher

BBSRC Discovery Fellow

 Not Known

 Geoffrey Pope 

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

Qualifications

2007 PhD Eukaryotic Gene Regulation, Trinity College Dublin, Ireland.
2003 MSc Molecular Medicine, Trinity College Dublin Ireland.
2002 BSc (Hons) Biology & Statistics, NUI Maynooth, Ireland.

Career

April 2022: BBSRC Discovery Fellow

May 2011 – April 2022: Research Fellow in University of Exeter.
2009 – 2011: Post-doctoral fellow. Ottawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
2009: Guest lecturer in Carleton University, Ottawa, Ontario, Canada.
2007 - 2009: Postdoctoral Researcher. Department of Microbiology, Trinity Collge Dublin. Ireland.

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Bedekovic T, Usher J (2023). Is There a Relationship Between Mating and Pathogenesis in Two Human Fungal Pathogens, Candida albicans and Candida glabrata?. Current Clinical Microbiology Reports, 10(2), 47-54. Abstract.
Usher J, Ribeiro GF, Childers DS (2023). The Candida glabrata Parent Strain Trap: How Phenotypic Diversity Affects Metabolic Fitness and Host Interactions. Microbiology Spectrum, 11(1). Abstract.
Stevenson EM, Gaze WH, Gow NAR, Hart A, Schmidt W, Usher J, Warris A, Wilkinson H, Murray AK (2022). Antifungal Exposure and Resistance Development: Defining Minimal Selective Antifungal Concentrations and Testing Methodologies. Frontiers in Fungal Biology, 3
Shahi G, Kumar M, Skwarecki AS, Edmondson M, Banerjee A, Usher J, Gow NAR, Milewski S, Prasad R (2022). Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor. The Cell Surface, 8 Abstract.
Usher J (2022). Using Synthetic Genetic Interactions in Candida glabrata as a Novel Method to Detect Genes with Roles in Antifungal Drug Resistance. Methods Mol Biol, 2542, 103-114. Abstract.  Author URL.
Halder V, McDonnell B, Uthayakumar D, Usher J, Shapiro RS (2021). Genetic interaction analysis in microbial pathogens: unravelling networks of pathogenesis, antimicrobial susceptibility and host interactions. FEMS Microbiol Rev, 45(3). Abstract.  Author URL.
Malavia D, Gow NAR, Usher J (2020). Advances in Molecular Tools and in Vivo Models for the Study of Human Fungal Pathogenesis. Microorganisms, 8(6), 803-803. Abstract.
Usher J, Chaudhari Y, Attah V, Ho H-L, Haynes K (2020). Functional Characterization of a Novel Oxidative Stress Protection Protein in the Pathogenic YeastCandida glabrata. FRONTIERS IN GENETICS, 11 Author URL.
Halder V, McDonnell B, Uthayakumar D, Usher J, Shapiro RS (2020). Genetic interaction analysis in microbial pathogens: unravelling networks of pathogenesis, antimicrobial susceptibility and host interactions. FEMS Microbiology Reviews, 45(3). Abstract.
Usher J, Haynes K (2019). Attenuating the emergence of anti-fungal drug resistance by harnessing synthetic lethal interactions in a model organism. PLoS Genet, 15(8). Abstract.  Author URL.
Paris JR, Usher J (2019). Functional genomic characterization of metallothioneins in brown trout (Salmo trutta L.). using synthetic genetic analysis. Scientific Reports, 9(1). Abstract.
Paris JR, Usher J (2019). Publisher Correction: Functional genomic characterization of metallothioneins in brown trout (Salmo trutta L.). using synthetic genetic analysis. Sci Rep, 9(1). Abstract.  Author URL.
Usher J (2019). The mechanisms of mating in pathogenic fungi-a plastic trait. Genes, 10(10), 1-18. Abstract.
Hobbs CAD, Potts RWA, Bjerregaard Walsh M, Usher J, Griffiths AM (2019). Using DNA Barcoding to Investigate Patterns of Species Utilisation in UK Shark Products Reveals Threatened Species on Sale. Sci Rep, 9(1). Abstract.  Author URL.
Sidhu YS, Chaudhari YK, Usher J, Cairns TC, Csukai M, Haynes K (2015). A suite of Gateway® compatible ternary expression vectors for functional analysis in Zymoseptoria tritici. Fungal Genet Biol, 79, 180-185. Abstract.  Author URL.
Sidhu YS, Cairns TC, Chaudhari YK, Usher J, Talbot NJ, Studholme DJ, Csukai M, Haynes K (2015). Exploitation of sulfonylurea resistance marker and non-homologous end joining mutants for functional analysis in Zymoseptoria tritici. Fungal Genet Biol, 79, 102-109. Abstract.  Author URL.
Usher J, Thomas G, Haynes K (2015). Utilising established SDL-screening methods as a tool for the functional genomic characterisation of model and non-model organisms. FEMS Yeast Res, 15(8). Abstract.  Author URL.
Kaloriti D, Tillmann A, Cook E, Jacobsen M, you T, Lenardon M, Ames L, Barahona M, Chandrasekaran K, Coghill G, et al (2012). Combinatorial stresses kill pathogenic Candida species. Med Mycol, 50(7), 699-709. Abstract.  Author URL.
Usher J, Berthelet S, Shulist K, Hamza A, Maltez N, Johnston A, Fong Y, Baetz K (2012). Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-independent Functions. , 185(3), 11111-11128.
Usher J, Balderas-Hernandez V, Quon P, Gold ND, Martin V, Mahadevan R, Baetz K (2011). Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae. G3: Genes, Genomes and Genetics, 1(4), 247-258.
Usher J, Bond U (2009). Recombination between homoeologous chromosomes of lager yeasts leads to loss of function of the hybrid GPH1 gene. Appl Environ Microbiol, 75(13), 4573-4579.
Usher J, James TC, Campbell S, Bond U (2008). Lager yeasts possess dynamic genomes that undergo rearrangements and gene amplification in response to stress. Current Genetics, 53(3), 139-152.

Publications by year


2023

Bedekovic T, Usher J (2023). Is There a Relationship Between Mating and Pathogenesis in Two Human Fungal Pathogens, Candida albicans and Candida glabrata?. Current Clinical Microbiology Reports, 10(2), 47-54. Abstract.
Usher J, Ribeiro GF, Childers DS (2023). The Candida glabrata Parent Strain Trap: How Phenotypic Diversity Affects Metabolic Fitness and Host Interactions. Microbiology Spectrum, 11(1). Abstract.

2022

Stevenson EM, Gaze WH, Gow NAR, Hart A, Schmidt W, Usher J, Warris A, Wilkinson H, Murray AK (2022). Antifungal Exposure and Resistance Development: Defining Minimal Selective Antifungal Concentrations and Testing Methodologies. Frontiers in Fungal Biology, 3
Shahi G, Kumar M, Skwarecki AS, Edmondson M, Banerjee A, Usher J, Gow NAR, Milewski S, Prasad R (2022). Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor. The Cell Surface, 8 Abstract.
Usher J (2022). Using Synthetic Genetic Interactions in Candida glabrata as a Novel Method to Detect Genes with Roles in Antifungal Drug Resistance. Methods Mol Biol, 2542, 103-114. Abstract.  Author URL.

2021

Halder V, McDonnell B, Uthayakumar D, Usher J, Shapiro RS (2021). Genetic interaction analysis in microbial pathogens: unravelling networks of pathogenesis, antimicrobial susceptibility and host interactions. FEMS Microbiol Rev, 45(3). Abstract.  Author URL.

2020

Malavia D, Gow NAR, Usher J (2020). Advances in Molecular Tools and in Vivo Models for the Study of Human Fungal Pathogenesis. Microorganisms, 8(6), 803-803. Abstract.
Usher J, Chaudhari Y, Attah V, Ho H-L, Haynes K (2020). Functional Characterization of a Novel Oxidative Stress Protection Protein in the Pathogenic YeastCandida glabrata. FRONTIERS IN GENETICS, 11 Author URL.
Halder V, McDonnell B, Uthayakumar D, Usher J, Shapiro RS (2020). Genetic interaction analysis in microbial pathogens: unravelling networks of pathogenesis, antimicrobial susceptibility and host interactions. FEMS Microbiology Reviews, 45(3). Abstract.

2019

Usher J, Haynes K (2019). Attenuating the emergence of anti-fungal drug resistance by harnessing synthetic lethal interactions in a model organism. PLoS Genet, 15(8). Abstract.  Author URL.
Paris JR, Usher J (2019). Functional genomic characterization of metallothioneins in brown trout (Salmo trutta L.). using synthetic genetic analysis. Scientific Reports, 9(1). Abstract.
Paris JR, Usher J (2019). Publisher Correction: Functional genomic characterization of metallothioneins in brown trout (Salmo trutta L.). using synthetic genetic analysis. Sci Rep, 9(1). Abstract.  Author URL.
Usher J (2019). The mechanisms of mating in pathogenic fungi-a plastic trait. Genes, 10(10), 1-18. Abstract.
Hobbs CAD, Potts RWA, Bjerregaard Walsh M, Usher J, Griffiths AM (2019). Using DNA Barcoding to Investigate Patterns of Species Utilisation in UK Shark Products Reveals Threatened Species on Sale. Sci Rep, 9(1). Abstract.  Author URL.

2015

Sidhu YS, Chaudhari YK, Usher J, Cairns TC, Csukai M, Haynes K (2015). A suite of Gateway® compatible ternary expression vectors for functional analysis in Zymoseptoria tritici. Fungal Genet Biol, 79, 180-185. Abstract.  Author URL.
Sidhu YS, Cairns TC, Chaudhari YK, Usher J, Talbot NJ, Studholme DJ, Csukai M, Haynes K (2015). Exploitation of sulfonylurea resistance marker and non-homologous end joining mutants for functional analysis in Zymoseptoria tritici. Fungal Genet Biol, 79, 102-109. Abstract.  Author URL.
Usher J, Thomas G, Haynes K (2015). Utilising established SDL-screening methods as a tool for the functional genomic characterisation of model and non-model organisms. FEMS Yeast Res, 15(8). Abstract.  Author URL.

2012

Kaloriti D, Tillmann A, Cook E, Jacobsen M, you T, Lenardon M, Ames L, Barahona M, Chandrasekaran K, Coghill G, et al (2012). Combinatorial stresses kill pathogenic Candida species. Med Mycol, 50(7), 699-709. Abstract.  Author URL.
Usher J, Berthelet S, Shulist K, Hamza A, Maltez N, Johnston A, Fong Y, Baetz K (2012). Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-independent Functions. , 185(3), 11111-11128.

2011

Usher J, Balderas-Hernandez V, Quon P, Gold ND, Martin V, Mahadevan R, Baetz K (2011). Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae. G3: Genes, Genomes and Genetics, 1(4), 247-258.

2009

Usher J, Bond U (2009). Recombination between homoeologous chromosomes of lager yeasts leads to loss of function of the hybrid GPH1 gene. Appl Environ Microbiol, 75(13), 4573-4579.

2008

Usher J, James TC, Campbell S, Bond U (2008). Lager yeasts possess dynamic genomes that undergo rearrangements and gene amplification in response to stress. Current Genetics, 53(3), 139-152.

Jane_Usher Details from cache as at 2023-09-27 08:15:31

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