Dr Jane Usher
BBSRC Discovery Fellow
J.Usher@exeter.ac.uk
Not Known
Geoffrey Pope
Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK
Overview
Qualifications
2007 PhD Eukaryotic Gene Regulation, Trinity College Dublin, Ireland.
2003 MSc Molecular Medicine, Trinity College Dublin Ireland.
2002 BSc (Hons) Biology & Statistics, NUI Maynooth, Ireland.
Career
April 2022: BBSRC Discovery Fellow
May 2011 – April 2022: Research Fellow in University of Exeter.
2009 – 2011: Post-doctoral fellow. Ottawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
2009: Guest lecturer in Carleton University, Ottawa, Ontario, Canada.
2007 - 2009: Postdoctoral Researcher. Department of Microbiology, Trinity Collge Dublin. Ireland.
Publications
Journal articles
Duggan S, Usher J (2023). Candida glabrata: a powerhouse of resistance. PLoS Pathog, 19(10). Author URL.
Bedekovic T, Usher J (2023). Is There a Relationship Between Mating and Pathogenesis in Two Human Fungal Pathogens, Candida albicans and Candida glabrata?. Current Clinical Microbiology Reports, 10(2), 47-54. Abstract.
Usher J, Ribeiro GF, Childers DS (2023). The Candida glabrata Parent Strain Trap: How Phenotypic Diversity Affects Metabolic Fitness and Host Interactions. Microbiology Spectrum, 11(1). Abstract.
Roselletti E, Pericolini E, Nore A, Takacs P, Kozma B, Sala A, De Seta F, Comar M, Usher J, Brown GD, et al (2023). Zinc prevents vaginal candidiasis by inhibiting expression of an inflammatory fungal protein. Science Translational Medicine, 15(725). Abstract.
Stevenson EM, Gaze WH, Gow NAR, Hart A, Schmidt W, Usher J, Warris A, Wilkinson H, Murray AK (2022). Antifungal Exposure and Resistance Development: Defining Minimal Selective Antifungal Concentrations and Testing Methodologies. Frontiers in Fungal Biology, 3
Shahi G, Kumar M, Skwarecki AS, Edmondson M, Banerjee A, Usher J, Gow NAR, Milewski S, Prasad R (2022). Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor. The Cell Surface, 8 Abstract.
Usher J (2022). Using Synthetic Genetic Interactions in Candida glabrata as a Novel Method to Detect Genes with Roles in Antifungal Drug Resistance. Methods Mol Biol, 2542, 103-114. Abstract. Author URL.
Halder V, McDonnell B, Uthayakumar D, Usher J, Shapiro RS (2021). Genetic interaction analysis in microbial pathogens: unravelling networks of pathogenesis, antimicrobial susceptibility and host interactions. FEMS Microbiol Rev, 45(3). Abstract. Author URL.
Malavia D, Gow NAR, Usher J (2020). Advances in Molecular Tools and in Vivo Models for the Study of Human Fungal Pathogenesis. Microorganisms, 8(6), 803-803. Abstract.
Usher J, Chaudhari Y, Attah V, Ho H-L, Haynes K (2020). Functional Characterization of a Novel Oxidative Stress Protection Protein in the Pathogenic Yeast<i>Candida glabrata</i>. FRONTIERS IN GENETICS, 11 Author URL.
Halder V, McDonnell B, Uthayakumar D, Usher J, Shapiro RS (2020). Genetic interaction analysis in microbial pathogens: unravelling networks of pathogenesis, antimicrobial susceptibility and host interactions. FEMS Microbiology Reviews, 45(3). Abstract.
Usher J, Haynes K (2019). Attenuating the emergence of anti-fungal drug resistance by harnessing synthetic lethal interactions in a model organism. PLoS Genet, 15(8). Abstract. Author URL.
Paris JR, Usher J (2019). Functional genomic characterization of metallothioneins in brown trout (Salmo trutta L.). using synthetic genetic analysis. Scientific Reports, 9(1). Abstract.
Paris JR, Usher J (2019). Publisher Correction: Functional genomic characterization of metallothioneins in brown trout (Salmo trutta L.). using synthetic genetic analysis. Sci Rep, 9(1). Abstract. Author URL.
Usher J (2019). The mechanisms of mating in pathogenic fungi-a plastic trait. Genes, 10(10), 1-18. Abstract.
Hobbs CAD, Potts RWA, Bjerregaard Walsh M, Usher J, Griffiths AM (2019). Using DNA Barcoding to Investigate Patterns of Species Utilisation in UK Shark Products Reveals Threatened Species on Sale. Sci Rep, 9(1). Abstract. Author URL.
Sidhu YS, Chaudhari YK, Usher J, Cairns TC, Csukai M, Haynes K (2015). A suite of Gateway® compatible ternary expression vectors for functional analysis in Zymoseptoria tritici. Fungal Genet Biol, 79, 180-185. Abstract. Author URL.
Sidhu YS, Cairns TC, Chaudhari YK, Usher J, Talbot NJ, Studholme DJ, Csukai M, Haynes K (2015). Exploitation of sulfonylurea resistance marker and non-homologous end joining mutants for functional analysis in Zymoseptoria tritici. Fungal Genet Biol, 79, 102-109. Abstract. Author URL.
Usher J, Thomas G, Haynes K (2015). Utilising established SDL-screening methods as a tool for the functional genomic characterisation of model and non-model organisms. FEMS Yeast Res, 15(8). Abstract. Author URL.
Kaloriti D, Tillmann A, Cook E, Jacobsen M, you T, Lenardon M, Ames L, Barahona M, Chandrasekaran K, Coghill G, et al (2012). Combinatorial stresses kill pathogenic Candida species. Med Mycol, 50(7), 699-709. Abstract. Author URL.
Usher J, Berthelet S, Shulist K, Hamza A, Maltez N, Johnston A, Fong Y, Baetz K (2012). Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-independent Functions. , 185(3), 11111-11128.
Usher J, Balderas-Hernandez V, Quon P, Gold ND, Martin V, Mahadevan R, Baetz K (2011). Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae. G3: Genes, Genomes and Genetics, 1(4), 247-258.
Usher J, Bond U (2009). Recombination between homoeologous chromosomes of lager yeasts leads to loss of function of the hybrid GPH1 gene. Appl Environ Microbiol, 75(13), 4573-4579.
Usher J, James TC, Campbell S, Bond U (2008). Lager yeasts possess dynamic genomes that undergo rearrangements and gene amplification in response to stress. Current Genetics, 53(3), 139-152.
Conferences
Usher J (2022). Functional genomics in <i>Candida glabrata</i>, new tools to study stress, pathogenesis and drug resistance. Author URL.
