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Dr Ruben Rogaciano Ramalho

Dr Ruben Rogaciano Ramalho

Postdoctoral Research Fellow

 Geoffrey Pope 

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

I’m a biochemist who became interested in the physics of life. After a PhD in the University of Lisbon working on microtubules and nanotechnology, I joined the Rousso Lab in Ben-Gurion University, working on how the mechanics of the HIV capsid shape the virus’s replication cycle. After a short project on nanotoxicology with the Torsten Lab in Basel University’s Biozentrum, I was keen on returning to the mechanobiology of pathogens, and I was lucky enough to be invited to join Alex Brand’s group in the MRC center for medical mycology.

Qualifications

Diploma (pre-Bologna Licenciate Degree) in Biochemistry from the Science Faculty of the University of Lisbon.

PhD in Biomedical Engineering from Instituto Superior Tecnico, (Technical) University of Lisbon.

Research group links

Research

Research interests

Mechanobiology, cellular biophysics and bionanotechnology.

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Rankovic S, Ramalho R, Aiken C, Rousso I (2018). PF74 Reinforces the HIV-1 Capsid to Impair Reverse Transcription-Induced Uncoating. Journal of Virology, 92(20). Abstract.
Rankovic S, Varadarajan J, Ramalho R, Aiken C, Rousso I (2017). Reverse Transcription Mechanically Initiates HIV-1 Capsid Disassembly. Journal of Virology, 91(12). Abstract.
Ramalho R, Rankovic S, Zhou J, Aiken C, Rousso I (2016). Analysis of the mechanical properties of wild type and hyperstable mutants of the HIV-1 capsid. Retrovirology, 13(1).
Liu C, Perilla JR, Ning J, Lu M, Hou G, Ramalho R, Himes BA, Zhao G, Bedwell GJ, Byeon I-J, et al (2016). Cyclophilin a stabilizes the HIV-1 capsid through a novel non-canonical binding site. Nature Communications, 7(1).
Basto AP, Piedade J, Ramalho R, Alves S, Soares H, Cornelis P, Martins C, Leitão A (2012). A new cloning system based on the OprI lipoprotein for the production of recombinant bacterial cell wall-derived immunogenic formulations. J Biotechnol, 157(1), 50-63. Abstract.  Author URL.
Ayouchi R, Schwarz R, Melo LV, Ramalho R, Alves E, Marques CP, Santos L, Almeida R, Conde O (2009). Morphological and optical properties of silicon thin films by PLD. Applied Surface Science, 255(10), 5299-5302.
Ramalho RR, Soares H, Melo LV (2007). Microtubule behavior under strong electromagnetic fields. Materials Science and Engineering: C, 27(5-8), 1207-1210.

Publications by year


2018

Rankovic S, Ramalho R, Aiken C, Rousso I (2018). PF74 Reinforces the HIV-1 Capsid to Impair Reverse Transcription-Induced Uncoating. Journal of Virology, 92(20). Abstract.

2017

Rankovic S, Varadarajan J, Ramalho R, Aiken C, Rousso I (2017). Reverse Transcription Mechanically Initiates HIV-1 Capsid Disassembly. Journal of Virology, 91(12). Abstract.

2016

Ramalho R, Rankovic S, Zhou J, Aiken C, Rousso I (2016). Analysis of the mechanical properties of wild type and hyperstable mutants of the HIV-1 capsid. Retrovirology, 13(1).
Liu C, Perilla JR, Ning J, Lu M, Hou G, Ramalho R, Himes BA, Zhao G, Bedwell GJ, Byeon I-J, et al (2016). Cyclophilin a stabilizes the HIV-1 capsid through a novel non-canonical binding site. Nature Communications, 7(1).

2012

Basto AP, Piedade J, Ramalho R, Alves S, Soares H, Cornelis P, Martins C, Leitão A (2012). A new cloning system based on the OprI lipoprotein for the production of recombinant bacterial cell wall-derived immunogenic formulations. J Biotechnol, 157(1), 50-63. Abstract.  Author URL.

2009

Ayouchi R, Schwarz R, Melo LV, Ramalho R, Alves E, Marques CP, Santos L, Almeida R, Conde O (2009). Morphological and optical properties of silicon thin films by PLD. Applied Surface Science, 255(10), 5299-5302.

2007

Ramalho RR, Soares H, Melo LV (2007). Microtubule behavior under strong electromagnetic fields. Materials Science and Engineering: C, 27(5-8), 1207-1210.

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Teaching

Supervision / Group

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