Loading content
Dr Ruth Carmichael

Dr Ruth Carmichael

Postdoctoral Research Fellow

 2173

 01392 722173

 Geoffrey Pope 211

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

I am a Postdoctoral Research Fellow in the lab of Prof. Michael Schrader, investigating the molecular mechanisms underlying peroxisome dynamics. My previous research has focused on how post-translational modifications regulate organelle function and protein trafficking in healthy and diseased states. In particular, my work on the dysfunction of mitochondrial dynamics in Parkinson’s Disease led me to an interest in peroxisomes, because of the shared machinery between the two organelles. In the Schrader lab, I will be using a variety of molecular, biochemical, imaging and biophysical techniques to investigate the how peroxisome number and function is controlled.

Qualifications

PhD (Bristol, 2017), MSci (Cambridge, 2012)

Career

2018-2021 Postdoctoral Research Fellow, University of Exeter

2017-2018 Research Associate in Biochemistry, University of Bristol

2016-2017 Research Associate in Cell Biology, University of the West of England

2012-2016 PhD in Molecular Neuroscience, University of Bristol

2008-2012 MSci in Biochemistry, University of Cambridge

Research group links

Research

Research interests

  • Organelle dynamics – peroxisomes and mitochondria
  • Intracellular trafficking
  • Post-translational modifications
  • Membrane proteins
  • Molecular neuroscience and neurodegeneration
  • Signalling pathways

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Carmichael RE, Wilkinson KA, Craig TJ (2019). Insulin-dependent GLUT4 trafficking is not regulated by protein SUMOylation in L6 myocytes. Scientific Reports, 9(1). Abstract.
Davey JS, Carmichael RE, Craig TJ (2019). Protein SUMOylation regulates insulin secretion at multiple stages. Scientific Reports, 9(1). Abstract.
Henley JM, Carmichael RE, Wilkinson KA (2018). Extranuclear SUMOylation in Neurons. Trends in Neurosciences, 41(4), 198-210. Abstract.
Carmichael RE, Wilkinson KA, Craig TJ, Ashby MC, Henley JM (2018). MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1. SCIENTIFIC REPORTS, 8 Author URL.
Zhu B, Carmichael RE, Valois LS, Wilkinson KA, Henley JM (2018). The transcription factor MEF2A plays a key role in the differentiation/ maturation of rat neural stem cells into neurons. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 500(3), 645-649. Author URL.
Carmichael RE, Henley JM (2018). Transcriptional and post-translational regulation of Arc in synaptic plasticity. Seminars in Cell and Developmental Biology, 77, 3-9. Abstract.
Carmichael RE, Boyce A, Matthewman C, Patron NJ (2015). An introduction to synthetic biology in plant systems: ERASynBio/OpenPlant summer school for early career researchers, September 2014. New Phytologist, 208(1), 20-22.
Luo J, Ashikaga E, Rubin PP, Heimann MJ, Hildick KL, Bishop P, Girach F, Josa-Prado F, Tang LTH, Carmichael RE, et al (2013). Receptor trafficking and the regulation of synaptic plasticity by SUMO. NeuroMolecular Medicine, 15(4), 692-706. Abstract.

Publications by year


2019

Carmichael RE, Wilkinson KA, Craig TJ (2019). Insulin-dependent GLUT4 trafficking is not regulated by protein SUMOylation in L6 myocytes. Scientific Reports, 9(1). Abstract.
Davey JS, Carmichael RE, Craig TJ (2019). Protein SUMOylation regulates insulin secretion at multiple stages. Scientific Reports, 9(1). Abstract.

2018

Henley JM, Carmichael RE, Wilkinson KA (2018). Extranuclear SUMOylation in Neurons. Trends in Neurosciences, 41(4), 198-210. Abstract.
Carmichael RE, Wilkinson KA, Craig TJ, Ashby MC, Henley JM (2018). MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1. SCIENTIFIC REPORTS, 8 Author URL.
Zhu B, Carmichael RE, Valois LS, Wilkinson KA, Henley JM (2018). The transcription factor MEF2A plays a key role in the differentiation/ maturation of rat neural stem cells into neurons. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 500(3), 645-649. Author URL.
Carmichael RE, Henley JM (2018). Transcriptional and post-translational regulation of Arc in synaptic plasticity. Seminars in Cell and Developmental Biology, 77, 3-9. Abstract.

2015

Carmichael RE, Boyce A, Matthewman C, Patron NJ (2015). An introduction to synthetic biology in plant systems: ERASynBio/OpenPlant summer school for early career researchers, September 2014. New Phytologist, 208(1), 20-22.

2013

Luo J, Ashikaga E, Rubin PP, Heimann MJ, Hildick KL, Bishop P, Girach F, Josa-Prado F, Tang LTH, Carmichael RE, et al (2013). Receptor trafficking and the regulation of synaptic plasticity by SUMO. NeuroMolecular Medicine, 15(4), 692-706. Abstract.

Ruth_Carmichael Details from cache as at 2019-08-26 01:36:30

Refresh publications

Teaching

Supervision / Group

Back | Edit Profile