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Dr Sumita Roy

Dr Sumita Roy

Postdoctoral Research Fellow

 Geoffrey Pope 328

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

Broad Research Specialisms:

Infectious diseases, Microbial Pathogenesis, Biochemistry, Structural biology

Qualifications

2002-2005: BSc in Biotechnology, Bangalore University (India).

2005-2006: MSc in Biomedical basis of diseases, Sheffield Hallam University, UK

2007-2010: PhD in Molecular microbiology, University of Sheffield, UK

Career

2017-Present: Postdoctoral researcher. Living System Institute. University of Exeter, UK

2015-2016: Women Research Fellowship. Indian Institute of Technology. Chennai, India

2011-2012: Research Associate. Imperial College London, UK

2010-2011: Wellcome Trust Fellowship. University of Sheffield, UK

Research

Research interests

Currently I am involved in investigating the molecular basis for the biosynthesis of the Coxiella burnetti O-antigen. In parallel, I am also engineering polysaccharide for “Click chemistry”.

Publications

Key publications | Publications by category | Publications by year

Key publications


Harmer NJ, Roy S, Vivoli M (2019). Carbohydrate Kinases: a Conserved Mechanism Across Differing Folds. Catalysts, 9, 29-29.
Phansopa C, Roy S, Rafferty JB, Douglas CWI, Pandhal J, Wright PC, Kelly DJ, Stafford GP (2014). Structural and functional characterization of NanU, a novel high-affinity sialic acid-inducible binding protein of oral and gut-dwelling Bacteroidetes species. Biochemical Journal, 458(3), 499-511. Abstract.
Roy S, Phansopa C, Stafford P, Honma K, Douglas CWI, Sharma A, Stafford GP (2012). Beta-hexosaminidase activity of the oral pathogen<i>Tannerella forsythia</i>influences biofilm formation on glycoprotein substrates. FEMS Immunology & Medical Microbiology, 65(1), 116-120.
Roy S, Honma K, Douglas CWI, Sharma A, Stafford GP (2011). Role of sialidase in glycoprotein utilization by Tannerella forsythia. Microbiology, 157(11), 3195-3202. Abstract.
Roy S, Douglas CWI, Stafford GP (2010). A Novel Sialic Acid Utilization and Uptake System in the Periodontal Pathogen. <i>Tannerella forsythia</i>. Journal of Bacteriology, 192(9), 2285-2293. Abstract.
Pham TK, Roy S, Noirel J, Douglas I, Wright PC, Stafford GP (2010). A quantitative proteomic analysis of biofilm adaptation by the periodontal pathogen <i>Tannerella forsythia</i>. PROTEOMICS, 10(17), 3130-3141.

Publications by category


Journal articles

Cross AR, Roy S, Vega MV, Rejzek M, Nepogodiev SA, Cliff M, Salmon D, Isupov MN, Field RA, Prior JL, et al (In Press). Spinning sugars in antigen biosynthesis: a direct study of the <i>Coxiella burnetii</i> and <i>Streptomyces griseus</i> TDP-sugar epimerases.  Abstract.
Roy S, Vega MV, Ames JR, Britten N, Kent A, Evans K, Isupov MN, Harmer NJ (In Press). Structure and function of <i>N</i>-acetylglucosamine kinase illuminates the catalytic mechanism of ROK kinases.  Abstract.
Cross AR, Roy S, Vivoli Vega M, Rejzek M, Nepogodiev SA, Cliff M, Salmon D, Isupov MN, Field RA, Prior JL, et al (2022). Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J Biol Chem, 298(5). Abstract.  Author URL.
Harmer NJ, Roy S, Vivoli M (2019). Carbohydrate Kinases: a Conserved Mechanism Across Differing Folds. Catalysts, 9, 29-29.
Cross AR, Baldwin VM, Roy S, Essex-Lopresti AE, Prior JL, Harmer NJ (2019). Zoonoses under our noses. Microbes Infect, 21(1), 10-19. Abstract.  Author URL.
Phansopa C, Roy S, Rafferty JB, Douglas CWI, Pandhal J, Wright PC, Kelly DJ, Stafford GP (2014). Structural and functional characterization of NanU, a novel high-affinity sialic acid-inducible binding protein of oral and gut-dwelling Bacteroidetes species. Biochemical Journal, 458(3), 499-511. Abstract.
Settem RP, Honma K, Nakajima T, Phansopa C, Roy S, Stafford GP, Sharma A (2012). A bacterial glycan core linked to surface (S)-layer proteins modulates host immunity through Th17 suppression. Mucosal Immunology, 6(2), 415-426.
Roy S, Phansopa C, Stafford P, Honma K, Douglas CWI, Sharma A, Stafford GP (2012). Beta-hexosaminidase activity of the oral pathogen<i>Tannerella forsythia</i>influences biofilm formation on glycoprotein substrates. FEMS Immunology & Medical Microbiology, 65(1), 116-120.
Roy S, Honma K, Douglas CWI, Sharma A, Stafford GP (2011). Role of sialidase in glycoprotein utilization by Tannerella forsythia. Microbiology, 157(11), 3195-3202. Abstract.
Stafford G, Roy S, Honma K, Sharma A (2011). Sialic acid, periodontal pathogens and Tannerella forsythia: stick around and enjoy the feast!. Molecular Oral Microbiology, 27(1), 11-22.
Roy S, Douglas CWI, Stafford GP (2010). A Novel Sialic Acid Utilization and Uptake System in the Periodontal Pathogen. <i>Tannerella forsythia</i>. Journal of Bacteriology, 192(9), 2285-2293. Abstract.
Pham TK, Roy S, Noirel J, Douglas I, Wright PC, Stafford GP (2010). A quantitative proteomic analysis of biofilm adaptation by the periodontal pathogen <i>Tannerella forsythia</i>. PROTEOMICS, 10(17), 3130-3141.
Pham TK, Roy S, Noirel J, Douglas I, Wright PC, Stafford GP (2010). A quantitative proteomic analysis of biofilm adaptation by the periodontal pathogen Tannerella forsythia. Proteomics Clinical Applications, 4(12), 965-965.

Publications by year


In Press

Cross AR, Roy S, Vega MV, Rejzek M, Nepogodiev SA, Cliff M, Salmon D, Isupov MN, Field RA, Prior JL, et al (In Press). Spinning sugars in antigen biosynthesis: a direct study of the <i>Coxiella burnetii</i> and <i>Streptomyces griseus</i> TDP-sugar epimerases.  Abstract.
Roy S, Vega MV, Ames JR, Britten N, Kent A, Evans K, Isupov MN, Harmer NJ (In Press). Structure and function of <i>N</i>-acetylglucosamine kinase illuminates the catalytic mechanism of ROK kinases.  Abstract.

2022

Cross AR, Roy S, Vivoli Vega M, Rejzek M, Nepogodiev SA, Cliff M, Salmon D, Isupov MN, Field RA, Prior JL, et al (2022). Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J Biol Chem, 298(5). Abstract.  Author URL.

2019

Harmer NJ, Roy S, Vivoli M (2019). Carbohydrate Kinases: a Conserved Mechanism Across Differing Folds. Catalysts, 9, 29-29.
Cross AR, Baldwin VM, Roy S, Essex-Lopresti AE, Prior JL, Harmer NJ (2019). Zoonoses under our noses. Microbes Infect, 21(1), 10-19. Abstract.  Author URL.

2014

Phansopa C, Roy S, Rafferty JB, Douglas CWI, Pandhal J, Wright PC, Kelly DJ, Stafford GP (2014). Structural and functional characterization of NanU, a novel high-affinity sialic acid-inducible binding protein of oral and gut-dwelling Bacteroidetes species. Biochemical Journal, 458(3), 499-511. Abstract.

2012

Settem RP, Honma K, Nakajima T, Phansopa C, Roy S, Stafford GP, Sharma A (2012). A bacterial glycan core linked to surface (S)-layer proteins modulates host immunity through Th17 suppression. Mucosal Immunology, 6(2), 415-426.
Roy S, Phansopa C, Stafford P, Honma K, Douglas CWI, Sharma A, Stafford GP (2012). Beta-hexosaminidase activity of the oral pathogen<i>Tannerella forsythia</i>influences biofilm formation on glycoprotein substrates. FEMS Immunology & Medical Microbiology, 65(1), 116-120.

2011

Roy S, Honma K, Douglas CWI, Sharma A, Stafford GP (2011). Role of sialidase in glycoprotein utilization by Tannerella forsythia. Microbiology, 157(11), 3195-3202. Abstract.
Stafford G, Roy S, Honma K, Sharma A (2011). Sialic acid, periodontal pathogens and Tannerella forsythia: stick around and enjoy the feast!. Molecular Oral Microbiology, 27(1), 11-22.

2010

Roy S, Douglas CWI, Stafford GP (2010). A Novel Sialic Acid Utilization and Uptake System in the Periodontal Pathogen. <i>Tannerella forsythia</i>. Journal of Bacteriology, 192(9), 2285-2293. Abstract.
Pham TK, Roy S, Noirel J, Douglas I, Wright PC, Stafford GP (2010). A quantitative proteomic analysis of biofilm adaptation by the periodontal pathogen <i>Tannerella forsythia</i>. PROTEOMICS, 10(17), 3130-3141.
Pham TK, Roy S, Noirel J, Douglas I, Wright PC, Stafford GP (2010). A quantitative proteomic analysis of biofilm adaptation by the periodontal pathogen Tannerella forsythia. Proteomics Clinical Applications, 4(12), 965-965.

Sumita_Roy Details from cache as at 2022-10-01 01:21:43

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