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Professor John Love

Professor John Love

Professor of Synthetic Biology

 5169

 Biocatalysis Centre BC2.1

 

Biocatalysis Centre, University of Exeter, The Henry Wellcome Building for Biocatalysis, Stocker Road, Exeter, EX4 4QD , UK

iGEM Team

Expedition to China

Overview

John Love is Professor of Synthetic Biology at the University of Exeter, which he joined as a lecturer in 2003. John’s research team is diverse and employs a multidisciplinary combination of technologies to investigate a range of questions, including – 

  • The production of “Fourth Generation” biofuels that can directly substitute for fossil petroleum-based products in modern car and jet engines; 
  • The biology of the hydrocarbon producing planktonic alga, Botryococcus braunii.
  • The integration of algal cultivation platforms for waste-nutrient recycling in the water purification industry; 
  • AI and machine-guided experimentation to engineer novel functions in bacteria; 
  • Cell-free genetic systems, and;
  • The forensic characterisation of anthropogenic microparticle pollutants since the industrial revolution in NW England.  

Industrial engagement and knowledge transfer is a leitmotif of our research; We have close partnerships with several businesses, from local SME’s to multinational companies.  John has held a BBSRC Industry Interchange Partnership with Shell where he led the photosynthetic microbial biofuels research programme.  He won the Industry Outstanding Impact in Science and Technology R&D Award for his research into innovative optics for flat-panel photobioreactors and the European Biophysics Award at the Società Italiana di Fisica International School of Physicsfor a paper entitled “Perfluorodecalin as an In-VivoMounting Medium”. In 2013, he won the Exeter Impact Award for Outstanding Impact in Technology and was a finalist in the 2014 BBSRC Innovator of the Year Award for the production of retail-grade diesel in bacteria.  

Since 2012 John’s laboratory has hosted the Exeter University iGEM team, going from Bronze to silver to four gold medals; in 2017, the team also won Best Environmental Project and Best Applied Design for a Synthetic Biology solution to remediate pollution from legacy of mining in the South West. 

Over the last decade, I have developed a unique expertise that fuses skills from academia and industry.  This unconventional course meant that I am unable to publish as freely as warranted by the ground-breaking nature of my research; rather I have an unusually large impact within relevant industries, as evidenced by the sources that fund my laboratory, by the number of industry-focused reports and patents that I have authored and by my ability to work productively with large and small companies to solve problems, as a research leader, collaborator and innovator.

Qualifications

1991-1994 PhD Cell & Molecular Biology, University of Edinburgh
1986-1990 BSc Biological Sciences, University of St Andrews

Career

2014-Current Professor of Synthetic Biology, College of Life and Environmental Sciences, University of Exeter

2011-2014 Associate Professor in Plant and Industrial Biotechnology, College of Life and Environmental Sciences, University of Exeter

2007-2011 Senior Lecturer in Plant Molecular Biology, School of Biosciences, University of Exeter

2003-2007 Lecturer in Developmental Biology, School of Biosciences, University of Exeter

2001-2003 Independent Broodbank Research Fellow, Department of Plant Sciences, University of Cambridge

1996-2001 Postdoctoral Research Associate, NASA Specialized Center for Research & Training, North Carolina State University

1995-1996 Postdoctoral Research Assistant, Institute of Cell & Molecular Biology, University of Edinburgh

Research group links

Research

Research interests

Synthetic Biology os a multidisciplinary endeavour that aime to rapidly translate cutting edge research into practicsal applications.  Our research programm,es reflect that impetus, and include,  

  • The production of “Fourth Generation” biofuels that can directly substitute for fossil petroleum-based products in modern car and jet engines by bacterial re-coding.
  • Machine-guided experimentation to engineer novel functions in bacteria.
  • The development and integration of algal cultivation platforms for waste-nutrient recycling in the water purification industry.
  • Cell-free genetic systems for field detection of diseases.
  • Forensic characterisation of anthropogenic microparticle pollutants and their effects on wellbeing.  
  • The biology of the hydrocarbon producing planktonic alga, Botryococcus braunii.

We have close partnerships with several businesses, from local SME’s to multinational companies.  Please do get in touch (J.Love@Exeter.ac.uk) if you believe that we can help you achieve your goals or simply want more information about what we do.

Publications

Key publications | Publications by category | Publications by year

Key publications


Love J, Graham SW, Irwin JA, Ashton PA, Bretagnolle F, Abbott RJ (2016). Self-pollination, style length development and seed set in self-compatible Asteraceae: evidence from Senecio vulgaris L. Plant Ecology and Diversity, 9(4), 371-379. Abstract.  Full text.
Gilman J, Love J (2016). Synthetic promoter design for new microbial chassis. Biochem Soc Trans, 44(3), 731-737. Abstract.  Author URL.  Full text.
Littlejohn GR, Mansfield JC, Parker D, Lind R, Perfect S, Seymour M, Smirnoff N, Love J, Moger J (2015). In vivo chemical and structural analysis of plant cuticular waxes using stimulated Raman scattering microscopy. Plant Physiol, 168(1), 18-28. Abstract.  Author URL.  Full text.
Littlejohn GR, Mansfield JC, Christmas JT, Witterick E, Fricker MD, Grant MR, Smirnoff N, Everson RM, Moger J, Love J, et al (2014). An update: improvements in imaging perfluorocarbon-mounted plant leaves with implications for studies of plant pathology, physiology, development and cell biology. Front Plant Sci, 5 Abstract.  Author URL.  Full text.
Lux TM, Lee R, Love J (2014). Genome-wide phylogenetic analysis of the pathogenic potential of Vibrio furnissii. Front Microbiol, 5 Abstract.  Author URL.  Full text.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.

Publications by category


Journal articles

Tennant RK, Jones RT, Brock F, Cook CG, Love J, Turney CSM, Lee R (In Press). A New Flow Cytometry Method Enabling Rapid Purification of Fossil Pollen from Terrestrial Sediments for AMS Radiocarbon Dating. Journal of Quaternary Science
Tennant RK, Ayine M, Power A, Gilman J, Hewlett M, James P, Singleton C, Parker D, Love J (2019). A Hybrid Sequencing Approach Completes the Genome Sequence of Thermoanaerobacter ethanolicus JW 200. Microbiology Resource Announcements, 8(3). Full text.
Singleton C, Gilman J, Rollit J, Zhang K, Parker DA, Love J (2019). A design of experiments approach for the rapid formulation of a chemically defined medium for metabolic profiling of industrially important microbes. PLoS One, 14(6). Abstract.  Author URL.  Full text.
Zhang K, Wells P, Liang Y, Love J, Parker DA, Botella C (2019). Effect of diluted hydrolysate as yeast propagation medium on ethanol production. Bioresour Technol, 271, 1-8. Abstract.  Author URL.  Full text.
Tennant RK, Holzer B, Love J, Tchilian E, White HN (2019). Higher levels of B-cell mutation in the early germinal centres of an inefficient secondary antibody response to a variant influenza haemagglutinin. Immunology, 157(1), 86-91. Abstract.  Author URL.  Full text.
Tennant RK, Lux T, Sambles C, Kuhn N, Petticrew E, Oldfield R, Parker D, Hatton J, Moore K, Lee R, et al (2019). Palaeogenomics of the Hydrocarbon Producing Microalga Botryococcus braunii. Scientific Reports, 9 Full text.
Gilman J, Singleton C, Tennant RK, James P, Howard TP, Lux T, Parker DA, Love J (2019). Rapid, Heuristic Discovery and Design of Promoter Collections in Non-Model Microbes for Industrial Applications. ACS Synth Biol, 8(5), 1175-1186. Abstract.  Author URL.  Full text.
Brown SR, Staff M, Lee R, Love J, Parker DA, Aves SJ, Howard TP (2018). Design of Experiments Methodology to Build a Multifactorial Statistical Model Describing the Metabolic Interactions of Alcohol Dehydrogenase Isozymes in the Ethanol Biosynthetic Pathway of the Yeast Saccharomyces cerevisiae. ACS Synth Biol, 7(7), 1676-1684. Abstract.  Author URL.  Full text.
Power A, Tennant RK, Jones RT, Tang Y, Du J, Worsley AT, Love J (2018). Monitoring Impacts of Urbanisation and Industrialisation on Air Quality in the Anthropocene Using Urban Pond Sediments. Frontiers in Earth Science, 6 Full text.
Burton BR, Tennant RK, Love J, Titball RW, Wraith DC, White HN (2018). Variant proteins stimulate more IgM+ GC B-cells revealing a mechanism of cross-reactive recognition by antibody memory. eLife Full text.
Shi H, Love J, Hu W (2017). Editorial: Melatonin in Plants. FRONTIERS IN PLANT SCIENCE, 8 Author URL.  Full text.
Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2. Full text.
Tennant RK, Sambles CM, Diffey GE, Moore KA, Love J (2017). Metagenomic Analysis of Silage. Journal of Visualized Experiments, 119, e54936-e54936. Full text.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga Botryococcus braunii. MicrobiologyOpen, 6(4), e00482-e00482. Full text.
Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.  Full text.
Johns AMB, Love J, Aves SJ (2016). Four Inducible Promoters for Controlled Gene Expression in the Oleaginous Yeast Rhodotorula toruloides. Front Microbiol, 7 Abstract.  Author URL.  Full text.
Love J, Graham SW, Irwin JA, Ashton PA, Bretagnolle F, Abbott RJ (2016). Self-pollination, style length development and seed set in self-compatible Asteraceae: evidence from Senecio vulgaris L. Plant Ecology and Diversity, 9(4), 371-379. Abstract.  Full text.
Gilman J, Love J (2016). Synthetic promoter design for new microbial chassis. Biochem Soc Trans, 44(3), 731-737. Abstract.  Author URL.  Full text.
Hutt H, Everson R, Grant M, Love J, Littlejohn G (2015). How clumpy is my image?: Scoring in crowdsourced annotation tasks. Soft Computing, 19(6), 1541-1552. Abstract.  Full text.
Littlejohn GR, Mansfield JC, Parker D, Lind R, Perfect S, Seymour M, Smirnoff N, Love J, Moger J (2015). In vivo chemical and structural analysis of plant cuticular waxes using stimulated Raman scattering microscopy. Plant Physiol, 168(1), 18-28. Abstract.  Author URL.  Full text.
Littlejohn GR, Mansfield JC, Christmas JT, Witterick E, Fricker MD, Grant MR, Smirnoff N, Everson RM, Moger J, Love J, et al (2014). An update: improvements in imaging perfluorocarbon-mounted plant leaves with implications for studies of plant pathology, physiology, development and cell biology. Front Plant Sci, 5 Abstract.  Author URL.  Full text.
Lux TM, Lee R, Love J (2014). Genome-wide phylogenetic analysis of the pathogenic potential of Vibrio furnissii. Front Microbiol, 5 Abstract.  Author URL.  Full text.
Reid EL, Weynberg KD, Love J, Isupov MN, Littlechild JA, Wilson WH, Kelly SL, Lamb DC, Allen MJ (2013). Functional and structural characterisation of a viral cytochrome b5. FEBS Lett, 587(22), 3633-3639. Abstract.  Author URL.
Hutt H, Everson R, Grant M, Love J, Littlejohn G (2013). How clumpy is my image? Evaluating crowdsourced annotation tasks. 2013 13th UK Workshop on Computational Intelligence, UKCI 2013, 136-143. Abstract.  Full text.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.
Love J, Tennant RK, Jones RT, Lee R (2012). A new flow cytometry enabling rapid purification of diatoms from silica-rich lacustrine sediments. Journal of Paleolimnology, 49(2), 305-309. Abstract.
Littlejohn GR, Love J (2012). A simple method for imaging Arabidopsis leaves using perfluorodecalin as an infiltrative imaging medium. Journal of visualized experiments : JoVE(59). Abstract.  Full text.
Debieux CM, Dridge EJ, Mueller CM, Splatt P, Paszkiewicz K, Knight I, Florance H, Love J, Titball RW, Lewis RJ, et al (2011). A bacterial process for selenium nanosphere assembly. Proc Natl Acad Sci U S A, 108(33), 13480-13485. Abstract.  Author URL.  Full text.
Reid EL, Worthy CA, Probert I, Ali ST, Love J, Napier J, Littlechild JA, Somerfield PJ, Allen MJ (2011). Coccolithophores: functional biodiversity, enzymes and bioprospecting. Mar Drugs, 9(4), 586-602. Abstract.  Author URL.  Full text.
Lux TM, Lee R, Love J (2011). Complete genome sequence of a free-living Vibrio furnissii sp. nov. strain (NCTC 11218). J Bacteriol, 193(6), 1487-1488. Author URL.  Full text.
Love J (2010). Conference report: Society for general microbiology bioenergy fuel sources symposium. Biofuels, 1(1), 15-17.
Littlejohn GR, Gouveia JD, Edner C, Smirnoff N, Love J (2010). Perfluorodecalin enhances in vivo confocal microscopy resolution of Arabidopsis thaliana mesophyll. New Phytol, 186(4), 1018-1025. Abstract.
Dodd AN, Gardner MJ, Hotta CT, Hubbard KE, Dalchau N, Robertson FC, Love J, Sanders D, Webb AAR (2009). Response to comment on "the Arabidopsis circadian clock incorporates a cADPR-based feedback loop". Science, 326(5950). Abstract.
Murphy AJ, Kemp F, Love J (2008). Surface plasmon resonance characterization of calspermin-calmodulin binding kinetics. Anal Biochem, 376(1), 61-72. Abstract.  Author URL.
Xu X, Hotta CT, Dodd AN, Love J, Sharrock R, Lee YW, Xie Q, Johnson CH, Webb AAR (2007). Distinct Light and Clock Modulation of Cytosolic Free Ca2+ Oscillations and Rhythmic CHLOROPHYLL A/B BINDING PROTEIN2 Promoter Activity in Arabidopsis. The Plant Cell, 19(11), 3474-3490.
Akesson A, Persson S, Love J, Boss WF, Widell S, Sommarin M (2005). Overexpression of the Ca2+-binding protein calreticulin in the endoplasmic reticulum improves growth of tobacco cell suspensions (Nicotiana tabacum) in high-Ca2+ medium. Physiologia Plantarum, 123(1), 92-99.
Love, J. Webb, A.R.R. (2005). The plant clock shows its metal: Circadian regulation of cytosolic free Ca2+. Trends in Plant Science, 10(1), 15-21.
Love J, Dodd AN, Webb ARR (2004). Circadian and diurnal calcium oscillations encode photoperiodic information in Arabidopsis. The Plant Cell, 16(4), 956-966.
Stevenson-Paulik J, Love J, Boss WF (2003). Differential regulation of two Arabidopsis type III phosphatidylinositol 4-kinase isoforms. A regulatory role for the pleckstrin homology domain. Plant Physiol, 132(2), 1053-1064. Abstract.  Author URL.
Love J, Allen GC, Gatz C, Thompson WF (2002). Differential Top10 promoter regulation by six tetracycline analogues in plant cells. Journal of Experimental Botany, 53(376), 1871-1877.
Perera IY, Love J, Heilmann I, Thompson WF, Boss WF (2002). Up-regulation of phosphoinositide metabolism in tobacco cells constitutively expressing the human type I inositol polyphosphate 5-phosphatase. Plant Physiol, 129(4), 1795-1806. Abstract.  Author URL.
Persson S, Love J, Tsou P-L, Robertson D, Thompson WF, Boss WF (2002). When a day makes a difference. Interpreting data from endoplasmic reticulum-targeted green fluorescent protein fusions in cells grown in suspension culture. Plant Physiol, 128(2), 341-344. Author URL.
Persson S, Wyatt SE, Love J, Thompson WF, Robertson D, Boss WF (2001). The Ca(2+) status of the endoplasmic reticulum is altered by induction of calreticulin expression in transgenic plants. Plant Physiol, 126(3), 1092-1104. Abstract.  Author URL.
Love J, Scott AC, Thompson WF (2000). Stringent control of transgene expression in Arabidopsis thaliana using the Top10 promoter system. Plant Journal, 21(6), 579-588. Abstract.
Moutinho A, Love J, Trewavas AJ, Malhó R (1998). Distribution of calmodulin protein and mRNA in growing pollen tubes. Sexual Plant Reproduction, 11(3), 131-139. Abstract.
Love J, Brownlee C, Trewavas AJ (1997). Ca2+ and Calmodulin Dynamics during Photopolarization in Fucus serratus Zygotes. Plant Physiol, 115(1), 249-261. Abstract.  Author URL.

Chapters

Murray AJ, Love J, Redwood MD, Orozco RL, Tennant RK, Woodhall F, Goodridge F, Macaskie LE (2018). Enhancement of Photosynthetic Productivity by Quantum Dots Application. In Stavrou VN (Ed) Nonmagnetic and Magnetic Quantum Dots, IntechOpen. Full text.
Cook C, Dayananda C, Tennant RK, Love J (2017). Third‐Generation Biofuels from the Microalga, Botryococcus braunii. In Love J, Bryant J (Eds.) Biofuels and Bioenergy, Wiley.

Conferences

LOVE J, TREWAVAS AJ (1995). CALMODULIN INVOLVEMENT IN POLARIZATION OF FUCUS-SERRATUS ZYGOTES.  Author URL.

Internet publications

Love J, Dodd AN, Gardner MJ, Webb ARR (2007). The Arabidopsis Circadian Clock Incorporates a cADPR-Based Feedback Loop .

Publications by year


In Press

Tennant RK, Jones RT, Brock F, Cook CG, Love J, Turney CSM, Lee R (In Press). A New Flow Cytometry Method Enabling Rapid Purification of Fossil Pollen from Terrestrial Sediments for AMS Radiocarbon Dating. Journal of Quaternary Science

2019

Tennant RK, Ayine M, Power A, Gilman J, Hewlett M, James P, Singleton C, Parker D, Love J (2019). A Hybrid Sequencing Approach Completes the Genome Sequence of Thermoanaerobacter ethanolicus JW 200. Microbiology Resource Announcements, 8(3). Full text.
Singleton C, Gilman J, Rollit J, Zhang K, Parker DA, Love J (2019). A design of experiments approach for the rapid formulation of a chemically defined medium for metabolic profiling of industrially important microbes. PLoS One, 14(6). Abstract.  Author URL.  Full text.
Reid T (2019). Developing synthetic consortia for industrial biofuel production from lignocellulose.  Abstract.  Full text.
Reid T (2019). Developing synthetic consortia for industrial biofuel production from lignocellulose.  Abstract.
Zhang K, Wells P, Liang Y, Love J, Parker DA, Botella C (2019). Effect of diluted hydrolysate as yeast propagation medium on ethanol production. Bioresour Technol, 271, 1-8. Abstract.  Author URL.  Full text.
Brain C (2019). Establishment of an Ensiling System for the Production of Lactic Acid from Sorghum bicolor (Sweet Sorghum) Biomass.  Abstract.  Full text.
Gachanja N (2019). Evaluation of Beta vulgaris as a Candidate Feedstock for Industrial Lactic Acid Production.  Abstract.  Full text.
Tennant RK, Holzer B, Love J, Tchilian E, White HN (2019). Higher levels of B-cell mutation in the early germinal centres of an inefficient secondary antibody response to a variant influenza haemagglutinin. Immunology, 157(1), 86-91. Abstract.  Author URL.  Full text.
Tennant RK, Lux T, Sambles C, Kuhn N, Petticrew E, Oldfield R, Parker D, Hatton J, Moore K, Lee R, et al (2019). Palaeogenomics of the Hydrocarbon Producing Microalga Botryococcus braunii. Scientific Reports, 9 Full text.
Gilman J, Singleton C, Tennant RK, James P, Howard TP, Lux T, Parker DA, Love J (2019). Rapid, Heuristic Discovery and Design of Promoter Collections in Non-Model Microbes for Industrial Applications. ACS Synth Biol, 8(5), 1175-1186. Abstract.  Author URL.  Full text.

2018

Brown SR, Staff M, Lee R, Love J, Parker DA, Aves SJ, Howard TP (2018). Design of Experiments Methodology to Build a Multifactorial Statistical Model Describing the Metabolic Interactions of Alcohol Dehydrogenase Isozymes in the Ethanol Biosynthetic Pathway of the Yeast Saccharomyces cerevisiae. ACS Synth Biol, 7(7), 1676-1684. Abstract.  Author URL.  Full text.
Murray AJ, Love J, Redwood MD, Orozco RL, Tennant RK, Woodhall F, Goodridge F, Macaskie LE (2018). Enhancement of Photosynthetic Productivity by Quantum Dots Application. In Stavrou VN (Ed) Nonmagnetic and Magnetic Quantum Dots, IntechOpen. Full text.
Power A, Tennant RK, Jones RT, Tang Y, Du J, Worsley AT, Love J (2018). Monitoring Impacts of Urbanisation and Industrialisation on Air Quality in the Anthropocene Using Urban Pond Sediments. Frontiers in Earth Science, 6 Full text.
Burton BR, Tennant RK, Love J, Titball RW, Wraith DC, White HN (2018). Variant proteins stimulate more IgM+ GC B-cells revealing a mechanism of cross-reactive recognition by antibody memory. eLife Full text.

2017

Shi H, Love J, Hu W (2017). Editorial: Melatonin in Plants. FRONTIERS IN PLANT SCIENCE, 8 Author URL.  Full text.
Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2. Full text.
Tennant RK, Sambles CM, Diffey GE, Moore KA, Love J (2017). Metagenomic Analysis of Silage. Journal of Visualized Experiments, 119, e54936-e54936. Full text.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga Botryococcus braunii. MicrobiologyOpen, 6(4), e00482-e00482. Full text.
Cook C, Dayananda C, Tennant RK, Love J (2017). Third‐Generation Biofuels from the Microalga, Botryococcus braunii. In Love J, Bryant J (Eds.) Biofuels and Bioenergy, Wiley.

2016

Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.  Full text.
Johns AMB, Love J, Aves SJ (2016). Four Inducible Promoters for Controlled Gene Expression in the Oleaginous Yeast Rhodotorula toruloides. Front Microbiol, 7 Abstract.  Author URL.  Full text.
Love J, Graham SW, Irwin JA, Ashton PA, Bretagnolle F, Abbott RJ (2016). Self-pollination, style length development and seed set in self-compatible Asteraceae: evidence from Senecio vulgaris L. Plant Ecology and Diversity, 9(4), 371-379. Abstract.  Full text.
Gilman J, Love J (2016). Synthetic promoter design for new microbial chassis. Biochem Soc Trans, 44(3), 731-737. Abstract.  Author URL.  Full text.

2015

Hutt H, Everson R, Grant M, Love J, Littlejohn G (2015). How clumpy is my image?: Scoring in crowdsourced annotation tasks. Soft Computing, 19(6), 1541-1552. Abstract.  Full text.
Littlejohn GR, Mansfield JC, Parker D, Lind R, Perfect S, Seymour M, Smirnoff N, Love J, Moger J (2015). In vivo chemical and structural analysis of plant cuticular waxes using stimulated Raman scattering microscopy. Plant Physiol, 168(1), 18-28. Abstract.  Author URL.  Full text.

2014

Littlejohn GR, Mansfield JC, Christmas JT, Witterick E, Fricker MD, Grant MR, Smirnoff N, Everson RM, Moger J, Love J, et al (2014). An update: improvements in imaging perfluorocarbon-mounted plant leaves with implications for studies of plant pathology, physiology, development and cell biology. Front Plant Sci, 5 Abstract.  Author URL.  Full text.
Lux TM, Lee R, Love J (2014). Genome-wide phylogenetic analysis of the pathogenic potential of Vibrio furnissii. Front Microbiol, 5 Abstract.  Author URL.  Full text.

2013

Reid EL, Weynberg KD, Love J, Isupov MN, Littlechild JA, Wilson WH, Kelly SL, Lamb DC, Allen MJ (2013). Functional and structural characterisation of a viral cytochrome b5. FEBS Lett, 587(22), 3633-3639. Abstract.  Author URL.
Hutt H, Everson R, Grant M, Love J, Littlejohn G (2013). How clumpy is my image? Evaluating crowdsourced annotation tasks. 2013 13th UK Workshop on Computational Intelligence, UKCI 2013, 136-143. Abstract.  Full text.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.

2012

Love J, Tennant RK, Jones RT, Lee R (2012). A new flow cytometry enabling rapid purification of diatoms from silica-rich lacustrine sediments. Journal of Paleolimnology, 49(2), 305-309. Abstract.
Littlejohn GR, Love J (2012). A simple method for imaging Arabidopsis leaves using perfluorodecalin as an infiltrative imaging medium. Journal of visualized experiments : JoVE(59). Abstract.  Full text.

2011

Debieux CM, Dridge EJ, Mueller CM, Splatt P, Paszkiewicz K, Knight I, Florance H, Love J, Titball RW, Lewis RJ, et al (2011). A bacterial process for selenium nanosphere assembly. Proc Natl Acad Sci U S A, 108(33), 13480-13485. Abstract.  Author URL.  Full text.
Reid EL, Worthy CA, Probert I, Ali ST, Love J, Napier J, Littlechild JA, Somerfield PJ, Allen MJ (2011). Coccolithophores: functional biodiversity, enzymes and bioprospecting. Mar Drugs, 9(4), 586-602. Abstract.  Author URL.  Full text.
Lux TM, Lee R, Love J (2011). Complete genome sequence of a free-living Vibrio furnissii sp. nov. strain (NCTC 11218). J Bacteriol, 193(6), 1487-1488. Author URL.  Full text.

2010

Love J (2010). Conference report: Society for general microbiology bioenergy fuel sources symposium. Biofuels, 1(1), 15-17.
Littlejohn GR, Gouveia JD, Edner C, Smirnoff N, Love J (2010). Perfluorodecalin enhances in vivo confocal microscopy resolution of Arabidopsis thaliana mesophyll. New Phytol, 186(4), 1018-1025. Abstract.

2009

Dodd AN, Gardner MJ, Hotta CT, Hubbard KE, Dalchau N, Robertson FC, Love J, Sanders D, Webb AAR (2009). Response to comment on "the Arabidopsis circadian clock incorporates a cADPR-based feedback loop". Science, 326(5950). Abstract.

2008

Murphy AJ, Kemp F, Love J (2008). Surface plasmon resonance characterization of calspermin-calmodulin binding kinetics. Anal Biochem, 376(1), 61-72. Abstract.  Author URL.

2007

Xu X, Hotta CT, Dodd AN, Love J, Sharrock R, Lee YW, Xie Q, Johnson CH, Webb AAR (2007). Distinct Light and Clock Modulation of Cytosolic Free Ca2+ Oscillations and Rhythmic CHLOROPHYLL A/B BINDING PROTEIN2 Promoter Activity in Arabidopsis. The Plant Cell, 19(11), 3474-3490.
Love J, Dodd AN, Gardner MJ, Webb ARR (2007). The Arabidopsis Circadian Clock Incorporates a cADPR-Based Feedback Loop .

2005

Akesson A, Persson S, Love J, Boss WF, Widell S, Sommarin M (2005). Overexpression of the Ca2+-binding protein calreticulin in the endoplasmic reticulum improves growth of tobacco cell suspensions (Nicotiana tabacum) in high-Ca2+ medium. Physiologia Plantarum, 123(1), 92-99.
Love, J. Webb, A.R.R. (2005). The plant clock shows its metal: Circadian regulation of cytosolic free Ca2+. Trends in Plant Science, 10(1), 15-21.

2004

Love J, Dodd AN, Webb ARR (2004). Circadian and diurnal calcium oscillations encode photoperiodic information in Arabidopsis. The Plant Cell, 16(4), 956-966.

2003

Stevenson-Paulik J, Love J, Boss WF (2003). Differential regulation of two Arabidopsis type III phosphatidylinositol 4-kinase isoforms. A regulatory role for the pleckstrin homology domain. Plant Physiol, 132(2), 1053-1064. Abstract.  Author URL.

2002

Love J, Allen GC, Gatz C, Thompson WF (2002). Differential Top10 promoter regulation by six tetracycline analogues in plant cells. Journal of Experimental Botany, 53(376), 1871-1877.
Perera IY, Love J, Heilmann I, Thompson WF, Boss WF (2002). Up-regulation of phosphoinositide metabolism in tobacco cells constitutively expressing the human type I inositol polyphosphate 5-phosphatase. Plant Physiol, 129(4), 1795-1806. Abstract.  Author URL.
Persson S, Love J, Tsou P-L, Robertson D, Thompson WF, Boss WF (2002). When a day makes a difference. Interpreting data from endoplasmic reticulum-targeted green fluorescent protein fusions in cells grown in suspension culture. Plant Physiol, 128(2), 341-344. Author URL.

2001

Persson S, Wyatt SE, Love J, Thompson WF, Robertson D, Boss WF (2001). The Ca(2+) status of the endoplasmic reticulum is altered by induction of calreticulin expression in transgenic plants. Plant Physiol, 126(3), 1092-1104. Abstract.  Author URL.

2000

Love J, Scott AC, Thompson WF (2000). Stringent control of transgene expression in Arabidopsis thaliana using the Top10 promoter system. Plant Journal, 21(6), 579-588. Abstract.

1998

Moutinho A, Love J, Trewavas AJ, Malhó R (1998). Distribution of calmodulin protein and mRNA in growing pollen tubes. Sexual Plant Reproduction, 11(3), 131-139. Abstract.

1997

Love J, Brownlee C, Trewavas AJ (1997). Ca2+ and Calmodulin Dynamics during Photopolarization in Fucus serratus Zygotes. Plant Physiol, 115(1), 249-261. Abstract.  Author URL.

1995

LOVE J, TREWAVAS AJ (1995). CALMODULIN INVOLVEMENT IN POLARIZATION OF FUCUS-SERRATUS ZYGOTES.  Author URL.

john_love Details from cache as at 2019-11-19 19:13:13

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External Engagement and Impact

Awards/Honorary fellowships

  • Dec. 2010: Winner of the Smart Solutions Excellence with Impact award for Outstanding Impact in Science and Technology R&D, in collaboration with Enlightened Designs Ltd.
  • Aug. 2010: Winner of the "European Biophysics Award" for presentation of the paper entitled "Perfluorodecalin as an In-Vivo Mounting Medium (Littlejohn G R and Love J)" at the Societa Italiana di Fisica International School of Physics "Enrico Fermi" CLXXVII Course "Advanced Methods in Optical Fluorescence Microscopy Towards Nanoscopy".
  • Mar. 2011: Winner of the "Most Innovative Lecturer 2010/11" in Biosciences and runner up for the "Most Innovative Lecturer" by the University of Exeter Students' Guild.
  • Mar. 2010: Awarded "Most Innovativve Lecturer 2009/10" and "Lecturer of the Year 2009/10" in Biosciences by the University of Exeter Students' Guild.
  • Mar. 2007: Awarded status of Fellow of the Higher Education Academy.

Committee/panel activities

  • Expert witness for the Nuffield Council on Bioethics Fact Finding Meeting on Biofuels, Mar. 2010.
  • Oct. 2008/12:  Elected member of the Society for Experimental Biology Cell Biology Section Committee.
  • Oct. 2008: Elected member of the Society for for General Microbiology Committee (Eukaryotic Division).

Invited lectures

  • July 2011:  Organiser of the Society for Experimental Biology 3-day symposium entitled “Frontiers in Algal biology”.
  • Mar. 2011:  Invited Speaker at the UK/Spain Algal Biofuels Workshop (Madrid), organised by the UK Science and Innovation Network (SIN) and the British Embassy in Madrid.
  • Feb. 2011: Invited Speaker. “Enhanced Algal Growth in Microlensed Photobioreactors”. Biofuels in the UK: Challenges and Opportunities; Industry/academia exchange conference organised by EuroCsiCon, London.
  • Feb. 2011: Invited Presentation:  “Hydrocarbon Production in Botryococcus braunii.” Shell India Markets PVT, Bangalore, India.
  • Jan. 2011: Invited Conference Presentation: “Enhanced Algal Growth in Microlensed Photobioreactors”.  Algal Bioenergy Symposium, University of Bath.
  • Jun. 2010: Invited Conference Presentation: “High Resolution Confocal Imaging in Air-filled Tissues”; Society for Experimental Biology annual meeting. Prague.
  • May 2010: Invited Seminar: “Single Cell Resolution of Circadian Ca2+ Dynamics Using Transgenic Biosensors” Imperial College, London.
  • May 2008:  Invited Seminar: “Organ and Single Cell Ca2+ Dynamics During Photoperiodism in Arabidopsis thaliana. Scottish Crop Research Institute.
  • Nov. 2006:  Invited Seminar: “Photoperiodic Information Encoded by Ca2+ Oscillations” University of Birmingham.
  • Jun. 2004:  Invited Seminar: “Photoperiodic Information Encoded by Ca2+ Oscillations” University of Edinburgh.

Workshops/Conferences organised

  • Organiser of the Society for Experimental Biology 3-day symposium entitled “Frontiers in Algal biology”. Glasgow,  July 2011.
  • Organiser of the “Biofuels” section of the Society for General Microbiology meeting in Edinburgh, Sep. 2009.

Teaching

As a Fellow of the Higher Education Academy, I am committed to excellence and innovation in teaching. In conjunction with my colleagues, I aim to foster an appreciation of Biological Sciences and an eagerness for learning through the integration of lectures, practical classes, research projects and self-development. 

I am the Director of Education and Director of undergraduate Plant Science.

I am co-director of the MSc programme in Food Security.

As a personal tutor to L1-L3 undergraduates, I believe in establishing an excellent rapport and working relationship with students. I have introduced several innovative practices into the biotechnology stream to raise awareness of employability skills and entrepreneurship, including inviting lecturers from Industry and Government Departments, an assessed teamwork presentation based on "Dragon's Den" and a seminar style module at Level 3.

I have been the module coordinator for: "Introduction to Biotechnology" (Bio1313), "High-Throughput Biotechnology" (Bio2073), "Developmental Biology" (bio2043/57), "Medical Biotechnology" (Bio3072) and "Essetials of Molecular Biology" (BioM503) and have lectured in the field of cell and molecular biology, including "Plant Biology" (Bio2-42) "Functional Genomics" (Bio3035) and "Cell Biology" (Bio3054).

 

 

 

 

 

Modules

2019/20


Supervision / Group

Research Fellows

  • Christine Sambles

Postgraduate researchers

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