Loading content
Dr Karen Moore

Dr Karen Moore

Experimental Officer - Exeter Sequencing Service

 6203

 Geoffrey Pope 313

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

I am a molecular biologist with a background in DNA replication and its integration with the cell cycle in plants and yeasts. I have worked on molecular and synthetic biology approaches in biofuels production where I focused on algal bacterial consortia. Currently, I work for Exeter Sequencing Service where I aim to develop next generation genetic approaches to enable improved understanding of genomic models.

Broad research specialisms

In the rapidly evolving field of genomics my aim is to assist scientists perform up to date quality experiments in a cost efficient manner. Three areas are important: first, optimization of routine NGS library preparation protocols including controls and using sequencing metrics to improve service delivery; second, to develop custom designed functional genomics assays for a wide range of aims and objectives and third, to provide training and consultancy to enable a successful genomics projects from start to end (including planning, sample management, experimental pipelines and bioinformatics analysis). Development of experimental pipelines and bioinformatics analysis is undertaken by Paul O’Neill.

Qualifications

2000    PhD Biological Sciences, University of Exeter, UK

1995    BSc hons Biological Sciences, University of Exeter, UK

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Mill J, Leung SK, Ribarska T, Hannon E, Smith A, Pishva E, Poschmann J, Moore K, Troakes C, Al-Sarraj S, et al (In Press). A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience Full text.
Wiredu Boakye D, Jaroenlak P, Prachumwat A, Williams TA, Bateman K, Itsathiphaisarn O, Sritunyalucksan K, Paszkiewicz K, Moore KA, Stentiford G, et al (In Press). Decay of the glycolytic pathway and adaptation to intranuclear parasitism within Enterocytozoonidae microsporidia. Environmental Microbiology Full text.
Warwick-Dugdale J, Moore K, Allen M, Temperton B (In Press). Long-read viral metagenomics captures abundant and microdiverse viral populations and their niche-defining genomic islands. PeerJ Full text.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (In Press). Transcriptional reprogramming of Trichoderma hamatum GD12 in soil during plant growth promotion and biological control of Sclerotinia sclerotiorum. Environmental Microbiology
Clark GC, Essex-Lopresti A, Moore KA, Williamson ED, Lukaszewski R, Paszkiewicz K, David J (2019). Common Host Responses in Murine Aerosol Models of Infection Caused by Highly Virulent Gram-Negative Bacteria from the Genera Burkholderia, Francisella and Yersinia. Pathogens, 8(4). Abstract.  Author URL.  Full text.
Warmington RJ, Kay W, Jeffries A, O'Neill P, Farbos A, Moore K, Bebber DP, Studholme DJ (2019). High-Quality Draft Genome Sequence of the Causal Agent of the Current Panama Disease Epidemic. Microbiol Resour Announc, 8(36). Abstract.  Author URL.
Tennant RK, Lux T, Sambles C, Kuhn N, Petticrew E, Oldfield R, Parker D, Hatton J, Moore K, Lee R, et al (2019). Palaeogenomics of the Hydrocarbon Producing Microalga Botryococcus braunii. Scientific Reports, 9 Full text.
Wideman JG, Monier A, Rodríguez-Martínez R, Leonard G, Cook E, Poirier C, Maguire F, Milner DS, Irwin NAT, Moore K, et al (2019). Unexpected mitochondrial genome diversity revealed by targeted single-cell genomics of heterotrophic flagellated protists. Nature Microbiology Full text.
Yemataw Z, Muzemil S, Ambachew D, Tripathi L, Tesfaye K, Chala A, Farbos A, O'Neill P, Moore K, Grant M, et al (2018). Genome sequence data from 17 accessions of Ensete ventricosum, a staple food crop for millions in Ethiopia. Data in Brief, 18, 285-293. Abstract.  Full text.
Morcrette H, Morgan MS, Farbos A, O'Neill P, Moore K, Titball RW, Studholme DJ (2018). Genome sequence of Staphylococcus aureus Ex1, isolated from a patient with spinal osteomyelitis. Genome Announcements, 6(26). Abstract.  Full text.
Smith A, Kaczmar A, Bamford RA, Smith C, Frustaci S, Kovacs-Simon A, O'Neill P, Moore K, Paszkiewicz K, Titball RW, et al (2018). The Culture Environment Influences Both Gene Regulation and Phenotypic Heterogeneity in Escherichia coli. FRONTIERS IN MICROBIOLOGY, 9 Author URL.  Full text.
Yang ZR, Bullifent HL, Moore K, Paszkiewicz K, Saint RJ, Southern SJ, Champion OL, Senior NJ, Sarkar-Tyson M, Oyston PCF, et al (2017). A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis. Sci Rep, 7 Abstract.  Author URL.  Full text.
Senior NJ, Sasidharan K, Saint RJ, Scott AE, Sarkar-Tyson M, Ireland PM, Bullifent HL, Rong Yang Z, Moore K, Oyston PCF, et al (2017). An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions. BMC Microbiology, 17(1). Abstract.  Full text.
Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2. Full text.
Tennant RK, Sambles CM, Diffey GE, Moore KA, Love J (2017). Metagenomic Analysis of Silage. Journal of Visualized Experiments, 119, e54936-e54936. Full text.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga Botryococcus braunii. MicrobiologyOpen, 6(4), e00482-e00482. Full text.
Mitchelmore PJ, Randall J, Bull MJ, Moore KA, O'Neill PA, Paszkiewicz K, Mahenthiralingam E, Scotton CJ, Sheldon CD, Withers NJ, et al (2017). Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax Abstract.  Author URL.  Full text.
Williams TA, Nakjang S, Campbell SE, Freeman MA, Eydal M, Moore K, Hirt RP, Embley TM, Williams BAP (2016). A recent whole-genome duplication divides populations of a globally-distributed microsporidian. Molecular Biology and Evolution Abstract.  Full text.
Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.  Full text.
Laver TW, Caswell RC, Moore KA, Poschmann J, Johnson MB, Owens MM, Ellard S, Paszkiewicz KH, Weedon MN (2016). Pitfalls of haplotype phasing from amplicon-based long-read sequencing. Sci Rep, 6 Abstract.  Author URL.  Full text.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (2016). Transcriptional reprogramming underpins enhanced plant growth promotion by the biocontrol fungus Trichoderma hamatum GD12 during antagonistic interactions with Sclerotinia sclerotiorum in soil. Molecular Plant Pathology, 17, 1425-1441. Abstract.  Full text.
Price SJ, Garner TWJ, Balloux F, Ruis C, Paszkiewicz KH, Moore K, Griffiths AGF (2015). A de novo Assembly of the Common Frog (Rana temporaria) Transcriptome and Comparison of Transcription Following Exposure to Ranavirus and Batrachochytrium dendrobatidis. PLoS One, 10(6). Abstract.  Author URL.  Full text.
Laver T, Harrison J, O'Neill PA, Moore K, Farbos A, Paszkiewicz K, Studholme DJ (2015). Assessing the performance of the Oxford Nanopore Technologies MinION. Biomolecular Detection and Quantification, 3, 1-8. Abstract.  Full text.
Uren Webster TM, Shears JA, Moore K, Santos EM (2015). Identification of conserved hepatic transcriptomic responses to 17β-estradiol using high-throughput sequencing in brown trout. Physiol Genomics, 47(9), 420-431. Abstract.  Author URL.  Full text.
MacGregor DR, Kendall SL, Florance H, Fedi F, Moore K, Paszkiewicz K, Smirnoff N, Penfield S (2015). Seed production temperature regulation of primary dormancy occurs through control of seed coat phenylpropanoid metabolism. New Phytol, 205(2), 642-652. Abstract.  Author URL.
Watson AK, Williams TA, Williams BAP, Moore KA, Hirt RP, Embley TM (2015). Transcriptomic profiling of host-parasite interactions in the microsporidian Trachipleistophora hominis. BMC Genomics Abstract.  Full text.
Harrison J, Moore K, Paszkiewicz K, Jones T, Grant M, Ambacheew D, Muzemil S, Studholme D (2014). A Draft Genome Sequence for Ensete ventricosum, the Drought-Tolerant “Tree Against Hunger”. Agronomy, 4, 13-33. Abstract.
Bertolini C, van Aerle R, Lampis S, Moore KA, Paszkiewicz K, Butler CS, Vallini G, van der Giezen M (2014). Draft Genome Sequence of Stenotrophomonas maltophilia SeITE02, a Gammaproteobacterium Isolated from Selenite-Contaminated Mining Soil. Genome Announc, 2(3). Abstract.  Author URL.
Chen M, MacGregor DR, Dave A, Florance H, Moore K, Paszkiewicz K, Smirnoff N, Graham IA, Penfield S (2014). Maternal temperature history activates Flowering Locus T in fruits to control progeny dormancy according to time of year. Proc Natl Acad Sci U S A, 111(52), 18787-18792. Abstract.  Author URL.
Milne SW, Cheetham J, Lloyd D, Shaw S, Moore K, Paszkiewicz KH, Aves SJ, Bates S (2014). Role of Candida albicans Tem1 in mitotic exit and cytokinesis. Fungal Genet Biol, 69, 84-95. Abstract.  Author URL.  Full text.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA -directed DNA methylation. Plant Journal, 75(5), 836-846. Abstract.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA-directed DNA methylation. Plant Journal
Taylor M, Moore K, Murray J, Aves SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10(11), 1154-1163. Full text.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2003). The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002). NATURE, 421(6918), 94-94. Author URL.
Hart EA, Bryant JA, Moore K, Aves SJ (2002). Fission yeast Cdc23 interactions with DNA replication initiation proteins. Curr Genet, 41(5), 342-348. Abstract.  Author URL.
Moore, K. Aves, S.J. (2001). Origins and complexes: the initiation of DNA replication. Journal of Experimental Botany, 52, 193-202.
Hunt C, Moore K, Xiang Z, Hurst SM, McDougall RC, Rajandream MA, Barrell BG, Gwilliam R, Wood V, Lyne MH, et al (2001). Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes. Yeast, 18(4), 355-361. Abstract.  Author URL.
Xiang Z, Moore K, Wood V, Rajandream MA, Barrell BG, Skelton J, Churcher CM, Lyne MH, Devlin K, Gwilliam R, et al (2000). Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5. Yeast, 16(15), 1405-1411. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). Identification of a Candida albicans homologue of the PHO85 gene, a negative regulator of the PHO system in Saccharomyces cerevisiae. Yeast, 16(11), 1045-1051. Abstract.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). The mating-type region of Schizosaccharomyces pombe h(-S) 972: Sequencing and analysis of 69 kb including the expressed matl locus. Yeast, 16(11), 1061-1067. Abstract.
Talbot NJ, McCafferty HRK, Ma M, Moore K, Hamer JE (1997). Nitrogen starvation of the rice blast fungus Magnaporthe grisea may act as an environmental cue for disease symptom expression. PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 50(3), 179-195. Author URL.

Chapters

Moore, K. Aves, S.J. (2008). Mcm10 and DNA replication in fission yeast. In Bryant J, Francis D (Eds.) The Eukaryotic Cell Cycle, Taylor & Francis, 45-69.

Publications by year


In Press

Mill J, Leung SK, Ribarska T, Hannon E, Smith A, Pishva E, Poschmann J, Moore K, Troakes C, Al-Sarraj S, et al (In Press). A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience Full text.
Wiredu Boakye D, Jaroenlak P, Prachumwat A, Williams TA, Bateman K, Itsathiphaisarn O, Sritunyalucksan K, Paszkiewicz K, Moore KA, Stentiford G, et al (In Press). Decay of the glycolytic pathway and adaptation to intranuclear parasitism within Enterocytozoonidae microsporidia. Environmental Microbiology Full text.
Warwick-Dugdale J, Moore K, Allen M, Temperton B (In Press). Long-read viral metagenomics captures abundant and microdiverse viral populations and their niche-defining genomic islands. PeerJ Full text.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (In Press). Transcriptional reprogramming of Trichoderma hamatum GD12 in soil during plant growth promotion and biological control of Sclerotinia sclerotiorum. Environmental Microbiology

2019

Clark GC, Essex-Lopresti A, Moore KA, Williamson ED, Lukaszewski R, Paszkiewicz K, David J (2019). Common Host Responses in Murine Aerosol Models of Infection Caused by Highly Virulent Gram-Negative Bacteria from the Genera Burkholderia, Francisella and Yersinia. Pathogens, 8(4). Abstract.  Author URL.  Full text.
Warmington RJ, Kay W, Jeffries A, O'Neill P, Farbos A, Moore K, Bebber DP, Studholme DJ (2019). High-Quality Draft Genome Sequence of the Causal Agent of the Current Panama Disease Epidemic. Microbiol Resour Announc, 8(36). Abstract.  Author URL.
Tennant RK, Lux T, Sambles C, Kuhn N, Petticrew E, Oldfield R, Parker D, Hatton J, Moore K, Lee R, et al (2019). Palaeogenomics of the Hydrocarbon Producing Microalga Botryococcus braunii. Scientific Reports, 9 Full text.
Wideman JG, Monier A, Rodríguez-Martínez R, Leonard G, Cook E, Poirier C, Maguire F, Milner DS, Irwin NAT, Moore K, et al (2019). Unexpected mitochondrial genome diversity revealed by targeted single-cell genomics of heterotrophic flagellated protists. Nature Microbiology Full text.

2018

Yemataw Z, Muzemil S, Ambachew D, Tripathi L, Tesfaye K, Chala A, Farbos A, O'Neill P, Moore K, Grant M, et al (2018). Genome sequence data from 17 accessions of Ensete ventricosum, a staple food crop for millions in Ethiopia. Data in Brief, 18, 285-293. Abstract.  Full text.
Morcrette H, Morgan MS, Farbos A, O'Neill P, Moore K, Titball RW, Studholme DJ (2018). Genome sequence of Staphylococcus aureus Ex1, isolated from a patient with spinal osteomyelitis. Genome Announcements, 6(26). Abstract.  Full text.
Smith A, Kaczmar A, Bamford RA, Smith C, Frustaci S, Kovacs-Simon A, O'Neill P, Moore K, Paszkiewicz K, Titball RW, et al (2018). The Culture Environment Influences Both Gene Regulation and Phenotypic Heterogeneity in Escherichia coli. FRONTIERS IN MICROBIOLOGY, 9 Author URL.  Full text.

2017

Yang ZR, Bullifent HL, Moore K, Paszkiewicz K, Saint RJ, Southern SJ, Champion OL, Senior NJ, Sarkar-Tyson M, Oyston PCF, et al (2017). A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis. Sci Rep, 7 Abstract.  Author URL.  Full text.
Senior NJ, Sasidharan K, Saint RJ, Scott AE, Sarkar-Tyson M, Ireland PM, Bullifent HL, Rong Yang Z, Moore K, Oyston PCF, et al (2017). An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions. BMC Microbiology, 17(1). Abstract.  Full text.
Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2. Full text.
Tennant RK, Sambles CM, Diffey GE, Moore KA, Love J (2017). Metagenomic Analysis of Silage. Journal of Visualized Experiments, 119, e54936-e54936. Full text.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga Botryococcus braunii. MicrobiologyOpen, 6(4), e00482-e00482. Full text.
Mitchelmore PJ, Randall J, Bull MJ, Moore KA, O'Neill PA, Paszkiewicz K, Mahenthiralingam E, Scotton CJ, Sheldon CD, Withers NJ, et al (2017). Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax Abstract.  Author URL.  Full text.

2016

Williams TA, Nakjang S, Campbell SE, Freeman MA, Eydal M, Moore K, Hirt RP, Embley TM, Williams BAP (2016). A recent whole-genome duplication divides populations of a globally-distributed microsporidian. Molecular Biology and Evolution Abstract.  Full text.
Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.  Full text.
Laver TW, Caswell RC, Moore KA, Poschmann J, Johnson MB, Owens MM, Ellard S, Paszkiewicz KH, Weedon MN (2016). Pitfalls of haplotype phasing from amplicon-based long-read sequencing. Sci Rep, 6 Abstract.  Author URL.  Full text.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (2016). Transcriptional reprogramming underpins enhanced plant growth promotion by the biocontrol fungus Trichoderma hamatum GD12 during antagonistic interactions with Sclerotinia sclerotiorum in soil. Molecular Plant Pathology, 17, 1425-1441. Abstract.  Full text.

2015

Price SJ, Garner TWJ, Balloux F, Ruis C, Paszkiewicz KH, Moore K, Griffiths AGF (2015). A de novo Assembly of the Common Frog (Rana temporaria) Transcriptome and Comparison of Transcription Following Exposure to Ranavirus and Batrachochytrium dendrobatidis. PLoS One, 10(6). Abstract.  Author URL.  Full text.
Laver T, Harrison J, O'Neill PA, Moore K, Farbos A, Paszkiewicz K, Studholme DJ (2015). Assessing the performance of the Oxford Nanopore Technologies MinION. Biomolecular Detection and Quantification, 3, 1-8. Abstract.  Full text.
Uren Webster TM, Shears JA, Moore K, Santos EM (2015). Identification of conserved hepatic transcriptomic responses to 17β-estradiol using high-throughput sequencing in brown trout. Physiol Genomics, 47(9), 420-431. Abstract.  Author URL.  Full text.
MacGregor DR, Kendall SL, Florance H, Fedi F, Moore K, Paszkiewicz K, Smirnoff N, Penfield S (2015). Seed production temperature regulation of primary dormancy occurs through control of seed coat phenylpropanoid metabolism. New Phytol, 205(2), 642-652. Abstract.  Author URL.
Watson AK, Williams TA, Williams BAP, Moore KA, Hirt RP, Embley TM (2015). Transcriptomic profiling of host-parasite interactions in the microsporidian Trachipleistophora hominis. BMC Genomics Abstract.  Full text.

2014

Harrison J, Moore K, Paszkiewicz K, Jones T, Grant M, Ambacheew D, Muzemil S, Studholme D (2014). A Draft Genome Sequence for Ensete ventricosum, the Drought-Tolerant “Tree Against Hunger”. Agronomy, 4, 13-33. Abstract.
Bertolini C, van Aerle R, Lampis S, Moore KA, Paszkiewicz K, Butler CS, Vallini G, van der Giezen M (2014). Draft Genome Sequence of Stenotrophomonas maltophilia SeITE02, a Gammaproteobacterium Isolated from Selenite-Contaminated Mining Soil. Genome Announc, 2(3). Abstract.  Author URL.
Chen M, MacGregor DR, Dave A, Florance H, Moore K, Paszkiewicz K, Smirnoff N, Graham IA, Penfield S (2014). Maternal temperature history activates Flowering Locus T in fruits to control progeny dormancy according to time of year. Proc Natl Acad Sci U S A, 111(52), 18787-18792. Abstract.  Author URL.
Milne SW, Cheetham J, Lloyd D, Shaw S, Moore K, Paszkiewicz KH, Aves SJ, Bates S (2014). Role of Candida albicans Tem1 in mitotic exit and cytokinesis. Fungal Genet Biol, 69, 84-95. Abstract.  Author URL.  Full text.

2013

Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA -directed DNA methylation. Plant Journal, 75(5), 836-846. Abstract.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA-directed DNA methylation. Plant Journal

2011

Taylor M, Moore K, Murray J, Aves SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10(11), 1154-1163. Full text.

2008

Moore, K. Aves, S.J. (2008). Mcm10 and DNA replication in fission yeast. In Bryant J, Francis D (Eds.) The Eukaryotic Cell Cycle, Taylor & Francis, 45-69.

2003

Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2003). The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002). NATURE, 421(6918), 94-94. Author URL.

2002

Hart EA, Bryant JA, Moore K, Aves SJ (2002). Fission yeast Cdc23 interactions with DNA replication initiation proteins. Curr Genet, 41(5), 342-348. Abstract.  Author URL.

2001

Moore, K. Aves, S.J. (2001). Origins and complexes: the initiation of DNA replication. Journal of Experimental Botany, 52, 193-202.
Hunt C, Moore K, Xiang Z, Hurst SM, McDougall RC, Rajandream MA, Barrell BG, Gwilliam R, Wood V, Lyne MH, et al (2001). Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes. Yeast, 18(4), 355-361. Abstract.  Author URL.

2000

Xiang Z, Moore K, Wood V, Rajandream MA, Barrell BG, Skelton J, Churcher CM, Lyne MH, Devlin K, Gwilliam R, et al (2000). Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5. Yeast, 16(15), 1405-1411. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). Identification of a Candida albicans homologue of the PHO85 gene, a negative regulator of the PHO system in Saccharomyces cerevisiae. Yeast, 16(11), 1045-1051. Abstract.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). The mating-type region of Schizosaccharomyces pombe h(-S) 972: Sequencing and analysis of 69 kb including the expressed matl locus. Yeast, 16(11), 1061-1067. Abstract.

1997

Talbot NJ, McCafferty HRK, Ma M, Moore K, Hamer JE (1997). Nitrogen starvation of the rice blast fungus Magnaporthe grisea may act as an environmental cue for disease symptom expression. PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 50(3), 179-195. Author URL.

karen_moore Details from cache as at 2019-12-07 15:53:17

Refresh publications

Karen Moore

Teaching

PhD Students (PG researchers) and Postdoctoral researchers:

The Wellcome Trust awarded the University a £1.5million  Institutional Strategic Support Fund (ISSF) in 2012, which allowed me to join the Biomedical Informatics Hub as a molecular biology applications specialist whilst continuing to supervise the preparation and running of NGS projects for Exeter Sequencing Service. Therefore, a minimum of 10% of my time will always be available to support pilot projects and offer training courses to any technician, PhD students, PDRAs or academic within the University.

Laboratory Science Apprentice

I supervise and train a laboratory science apprentice (level 3) who works 4 days a week in the ESS laboratory and attends South Devon Collage for 1 day a week. I liaise with the collage tutors to ensure a coordinated training scheme.

PoreCamp

I was involved in 42 participants from 13 countries generated over 5Tb of sequencing data during the University of Exeter Porecamp held at Penryn Campus in Cornwall during 15-19 August 2016. Groups generated data for over 36 projects for sequencing on Oxford Nanopore’s MinION platform. These including WGS bacterial sequencing, PCR amplicons and BAC sequencing to help close mammalian genomes.

Supervision / Group

Back | Edit Profile