Dr Joseph Costello

About me:

I am a molecular cell biologist interested in how interaction between organelles allows coordination of cellular trafficking and signaling. I did my PhD at the University of Sheffield and then postdoctoral work at the University of Manchester where I investigated how cells can optimise mRNA selection under different stress conditions. Following this I moved to the University of Exeter where I worked on a critical stress-response organelle, the peroxisome. Here, I identified organelle-targeting signals for membrane proteins, allowing us to discover proteins which tether peroxisomes and the ER at membrane contact sites. I took up a lectureship in Exeter in 2019 and I am focusing on membrane contact sites between organelles and how this relates to ROS homeostasis and disease.