Professor Mark Ramsdale

About me:

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I am a member of the Microbes and Disease research theme.

The main focus of work in my lab is to further our understanding of stress and programmed cell death responses exhibited by fungi (in particular Candida albicans). This is important since fungal diseases of man have assumed great significance due to changes in the demographic status of the human population, changes in the management practices for chronic health conditions, and the increased use of immunocompromising agents in medicine. Due to similarities in the basic cellular organization of pathogenic fungi and their animal hosts, the control of such diseases poses considerable problems for clinicians. New strategies must therefore be implemented to assist in the identification of novel antifungal agents. We are therefore aiming to (i) identify and characterize the different types of cell death response (apoptotic, autophagic and necrotic) shown by fungi under different conditions, (ii) highlight the key differences between the cell death and stress responses of mammals and fungi, and (iii) identify regulators core to the fungal cell death response using a combination of traditional genetics and genomics based technologies.

2006-2007 Postgraduate Certificate in Academic Practice, University of Exeter
1995 PhD Biological Sciences, University of Bath
1991 BSc (Hons) Applied Biology, University of Bath

2015 - present Director of Education (Biosciences)

2006-2015 Lecturer in Molecular Microbiology, School of Biosciences, University of Exeter

2004-2006 Independent Research Fellow, School of Medical Sciences, University of Aberdeen

2000-2003 Lloyds Tercentenary Foundation Fellow, School of Medical Sciences, University of Aberdeen

1998-2000 Research Fellow, School of Medical Sciences, University of Aberdeen

1996-1998 Research Fellow, Department of Zoology, University of Cambridge

1995-1996 Scientist, Pfizer, Sandwich, Kent