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Faculty of Health and Life Sciences

Dr Aaron Butt

Dr Aaron Butt

Research Fellow

 A.T.Butt@exeter.ac.uk

 Not Known

 Geoffrey Pope Lab 401

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK


Overview

Qualifications

PhD Biological Sciences (Exeter)

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Research

Research projects

2013-15: Filling the target void: Identification of novel antibacterial therapeutics

Work includes:

  • Constructing deletion or conditional mutants in genes predicted to be essential in either growth or virulence
  • Determine the phenotype of these mutants in appropriate assays
  • Collaborate with biochemists to solve the protein structure of novel targets and to design inhibitors as therapeutics.

PhD project:

2009-13: Identification and characterisation of Toxin-antitoxin systems in Burkholderia pseudomallei

The aim of this project was to identify novel Toxin-antitoxin systems in B pseudomallei, the causative agent of melioidosis and elucidate their biological role in persister cell formation and chronic persistent disease.

Grants/Funding:

  • Defence Science and Technology Laboratory (DSTL)

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