Skip to main content

Profile

Loading content
Mr Joseph Pinion

Mr Joseph Pinion

MPH student

 Geoffrey Pope 201

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

I am PhD student working on alternative approaches to seizure liability testing in larval zebrafish.

 

Qualifications

Medical Sciences BSc, MRes 

 

Career

2018 - Present: PhD Researcher, University of Exeter 

Research

Research interests

Broad research specialisms:

  • Neuropharmacology
  • Brain Functional Imaging 
    • Calcium Imaging
    • Light-sheet Microscopy
  • Brain Network Connectomics
  • Zebrafish Brain Electrophysiology

Research projects

Project Title: An alternative approach for assessing drug-induced seizures, using non-protected larval zebrafish.

Supervisors: Charles Tyler, Matthew Winter, Andy Randall, Marc Goodfellow

Funding Body: NC3Rs

Project Description: We are using non-protected life-stage larval zebrafish for the detection of drugs with the potential to trigger seizures. .

Links


Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Pinion J, Walsh C, Goodfellow M, Randall AD, Tyler CR, Winter MJ (2022). Differential Electrographic Signatures Generated by Mechanistically-Diverse Seizurogenic Compounds in the Larval Zebrafish Brain. eNeuro, 9(2). Abstract.  Author URL.
Winter MJ, Pinion J, Tochwin A, Takesono A, Ball JS, Grabowski P, Metz J, Trznadel M, Tse K, Redfern WS, et al (2021). Functional brain imaging in larval zebrafish for characterising the effects of seizurogenic compounds acting via a range of pharmacological mechanisms. Br J Pharmacol, 178(13), 2671-2689. Abstract.  Author URL.
Reichmann F, Rimmer N, Tilley CA, Dalla Vecchia E, Pinion J, Al Oustah A, Carreño Gutiérrez H, Young AMJ, McDearmid JR, Winter MJ, et al (2020). The zebrafish histamine H3 receptor modulates aggression, neural activity and forebrain functional connectivity. Acta Physiologica, 230(4). Abstract.
Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, et al (2018). Author Correction: 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Sci Rep, 8(1). Abstract.  Author URL.
Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, et al (2017). 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Sci Rep, 7(1). Abstract.  Author URL.

Publications by year


2023

Pinion J (2023). An alternative approach for assessing drug induced seizures, using non-protected larval zebrafish.  Abstract.

2022

Pinion J, Walsh C, Goodfellow M, Randall AD, Tyler CR, Winter MJ (2022). Differential Electrographic Signatures Generated by Mechanistically-Diverse Seizurogenic Compounds in the Larval Zebrafish Brain. eNeuro, 9(2). Abstract.  Author URL.

2021

Winter MJ, Pinion J, Tochwin A, Takesono A, Ball JS, Grabowski P, Metz J, Trznadel M, Tse K, Redfern WS, et al (2021). Functional brain imaging in larval zebrafish for characterising the effects of seizurogenic compounds acting via a range of pharmacological mechanisms. Br J Pharmacol, 178(13), 2671-2689. Abstract.  Author URL.

2020

Reichmann F, Rimmer N, Tilley CA, Dalla Vecchia E, Pinion J, Al Oustah A, Carreño Gutiérrez H, Young AMJ, McDearmid JR, Winter MJ, et al (2020). The zebrafish histamine H3 receptor modulates aggression, neural activity and forebrain functional connectivity. Acta Physiologica, 230(4). Abstract.

2019

Pinion J (2019). Concordant spatio-temporal patterns of brain activation in zebrafish exposed to compounds with similar pharmacodynamics or with similar seizurogenic potential.  Abstract.

2018

Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, et al (2018). Author Correction: 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Sci Rep, 8(1). Abstract.  Author URL.

2017

Winter MJ, Windell D, Metz J, Matthews P, Pinion J, Brown JT, Hetheridge MJ, Ball JS, Owen SF, Redfern WS, et al (2017). 4-dimensional functional profiling in the convulsant-treated larval zebrafish brain. Sci Rep, 7(1). Abstract.  Author URL.

Joseph_Pinion Details from cache as at 2024-02-28 11:32:06

Refresh publications

Teaching

Supervision / Group

Back | Edit Profile