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Mr Joseph Pinion

Mr Joseph Pinion

MPH student

 Geoffrey Pope 201

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

I am PhD student working on alternative approaches to seizure liability testing in larval zebrafish.

 

Qualifications

Medical Sciences BSc, MRes 

 

Career

2018 - Present: PhD Researcher, University of Exeter 

Research

Research interests

‚ÄčBroad research specialisms:

  • Neuropharmacology
  • Brain Functional Imaging 
    • Calcium Imaging
    • Light-sheet Microscopy
  • Brain Network Connectomics
  • Zebrafish Brain Electrophysiology

Research projects

Project Title: An alternative approach for assessing drug-induced seizures, using non-protected larval zebrafish.

Supervisors: Charles Tyler, Matthew Winter, Andy Randall, Marc Goodfellow

Funding Body: NC3Rs

Project Description: We are using non-protected life-stage larval zebrafish for the detection of drugs with the potential to trigger seizures. .

Links


Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Pinion J, Walsh C, Goodfellow M, Randall AD, Tyler CR, Winter MJ (2022). Differential Electrographic Signatures Generated by Mechanistically-Diverse Seizurogenic Compounds in the Larval Zebrafish Brain. eNeuro, 9(2). Abstract.  Author URL.

Publications by year


2022

Pinion J, Walsh C, Goodfellow M, Randall AD, Tyler CR, Winter MJ (2022). Differential Electrographic Signatures Generated by Mechanistically-Diverse Seizurogenic Compounds in the Larval Zebrafish Brain. eNeuro, 9(2). Abstract.  Author URL.

2019

Pinion J (2019). Concordant spatio-temporal patterns of brain activation in zebrafish exposed to compounds with similar pharmacodynamics or with similar seizurogenic potential.  Abstract.  Full text.

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Teaching

Supervision / Group

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