Miss Milena Marinkovic
Graduate Research Assistant (Marie Curie Early Stage Researcher) (LSI)
Living Systems Institute T04.01
Living Systems Institute, University of Exeter, Stocker Road, Exeter, EX4 4QD
BSc Molecular Biology and Physiology, Faculty of Biology, University of Belgrade, Serbia (2013-17)
Visiting scientist at EMBL Heidelberg (Germany), Arendt group (2017-18)
EVOLUTION OF CILIOMOTOR NEURONS (PhD project)
The project focuses on ciliomotor neurons in the larvae of the marine annelid Platynereis dumerilii, that have recently been completely mapped by serial electron microscopy.
The ciliomotor system of Platynereis larvae consists of groups of cholinergic, serotonergic, dopaminergic, and adrenergic neurons. Neurons with the same transmitter identity in this circuit often have similar but non-identical projection patterns and synaptic connections. The main goal of the project is to dissect differences in the transcriptomes of these cells, and how they relate to differences in function and connectivity. The project involves a combination of approaches, including transgenesis, single-cell transcriptomics, neuronal activity imaging, and single neuron ablations.
The PhD project ''Evolution of ciliomotor neurons'' is a part of the EvoCell network. EvoCELL is a Marie Skłodowska-Curie Innovative Training Network aiming at studying the evolution of cell-types and tissues in a diverse array of vertebrates and invertebrates. To do so, the labs involved in the network use the most recent single-cell and tissue genomic techniques, merging them with more traditional disciplines. EvoCELL offers ambitious training programme, also in the non-academic sector. Scientific outreach and communication of the project results to a wider public are a fundamental part of the project and all fellows will contribute to it. The network brings together 8 academic and 2 non-academic organisations from 6 European countries.