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Faculty of Health and Life Sciences

Dr Sally Rogers

Dr Sally Rogers

Senior Lecturer

 S.Rogers@exeter.ac.uk

 3483

 Geoffrey Pope 214

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK


Overview

I am a Senior Lecturer in Molecular and Cellular Biology in the Bioscience department. I have extensive experience of teaching a wide range of topics across different levels, and I am a Fellow of the HEA.  I have worked in Research Institutes and Universities in the UK and Canada, and have published numerous articles in the field of cell signalling. 

Qualifications

Fellow of HEA

PhD (University of Bristol)

PGCE (University of Gloucestershire)

BSc (University of Bristol)

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Research

Research interests

My research has covered many aspects of molecular and cellular biology, from evolution of the immune system to regulation of gene expression post bone marrow transplant and signalling in gastric cancer.  The common theme has been the structure and function of cell signalling receptors. I have worked in research institutes in both the UK and Canada, using a wide range of molecular, cell culture and imaging techniques. 

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Publications

Journal articles

Zhang C, Brunt L, Ono Y, Rogers S, Scholpp S (2024). Cytoneme-mediated transport of active Wnt5b-Ror2 complexes in zebrafish. Nature, 625(7993), 126-133. Abstract.  Author URL.
Rogers S, Zhang C, Anagnostidis V, Liddle C, Fishel ML, Gielen F, Scholpp S (2023). Cancer-associated fibroblasts influence Wnt/PCP signaling in gastric cancer cells by cytoneme-based dissemination of ROR2. Proceedings of the National Academy of Sciences, 120(39). Abstract.
Weischedel J, Higgins L, Rogers S, Gramalla-Schmitz A, Wyrzykowska P, Borgoni S, MacCarthy T, Chahwan R (2023). Modular cytosine base editing promotes epigenomic and genomic modifications. Nucleic Acids Research, 52(2), e8-e8. Abstract.
Routledge D, Rogers S, Ono Y, Brunt L, Meniel V, Tornillo G, Ashktorab H, Phesse TJ, Scholpp S (2022). The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer. eLife, 11 Abstract.
Rogers S, Scholpp S (2022). Vertebrate Wnt5a – at the crossroads of cellular signalling. Seminars in Cell & Developmental Biology, 125, 3-10.
Wyrzykowska P, Rogers S, Chahwan R (2021). Measuring Real-time DNA/RNA Nuclease Activity through Fluorescence. BIO-PROTOCOL, 11(21).
Brunt L, Greicius G, Rogers S, Evans BD, Virshup DM, Wedgwood KCA, Scholpp S (2021). Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling. Nat Commun, 12(1). Abstract.  Author URL.
Sheppard EC, Rogers S, Harmer NJ, Chahwan R (2019). A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity. Sci Rep, 9(1). Abstract.  Author URL.
Rogers SL, Kaufman J (2016). Location, location, location: the evolutionary history of CD1 genes and the NKR-P1/ligand systems. Immunogenetics, 68(8), 499-513. Abstract.
Salomonsen J, Chattaway JA, Chan ACY, Parker A, Huguet S, Marston DA, Rogers SL, Wu Z, Smith AL, Staines K, et al (2014). Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns. PLoS Genetics, 10(6), e1004417-e1004417.
Rogers SL, Zhao Y, Jiang X, Eaves CJ, Mager DL, Rouhi A (2010). Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia. Mol Cancer, 9 Abstract.  Author URL.
Lai CB, Zhang Y, Rogers SL, Mager DL (2009). Creation of the two isoforms of rodent NKG2D was driven by a B1 retrotransposon insertion. Nucleic Acids Res, 37(9), 3032-3043. Abstract.  Author URL.
Rogers SL, Viertlboeck BC, Göbel TW, Kaufman J (2008). Avian NK activities, cells and receptors. Seminars in Immunology, 20(6), 353-360.
Rogers SL, Kaufman J (2008). High allelic polymorphism, moderate sequence diversity and diversifying selection for B-NK but not B-lec, the pair of lectin-like receptor genes in the chicken MHC. Immunogenetics, 60(8), 461-475. Abstract.  Author URL.
Rogers SL, Rouhi A, Takei F, Mager DL (2006). A role for DNA hypomethylation and histone acetylation in maintaining allele-specific expression of mouse NKG2A in developing and mature NK cells. J Immunol, 177(1), 414-421. Abstract.  Author URL.
Rogers SL, Göbel TW, Viertlboeck BC, Milne S, Beck S, Kaufman J (2005). Characterization of the chicken C-type lectin-like receptors B-NK and B-lec suggests that the NK complex and the MHC share a common ancestral region. J Immunol, 174(6), 3475-3483. Abstract.  Author URL.
Salomonsen J, Sørensen MR, Marston DA, Rogers SL, Collen T, van Hateren A, Smith AL, Beal RK, Skjødt K, Kaufman J, et al (2005). Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC. Proc Natl Acad Sci U S A, 102(24), 8668-8673. Abstract.  Author URL.
Wong GK-S, Liu B, Wang J, Zhang Y, Yang X, Zhang Z, Meng Q, Zhou J, Li D, Zhang J, et al (2004). A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature, 432(7018), 717-722. Abstract.  Author URL.
Rogers S, Shaw I, Ross N, Nair V, Rothwell L, Kaufman J, Kaiser P (2003). Analysis of part of the chicken Rfp-Y region reveals two novel lectin genes, the first complete genomic sequence of a class I alpha-chain gene, a truncated class II beta-chain gene, and a large CR1 repeat. Immunogenetics, 55(2), 100-108. Abstract.  Author URL.

Chapters

Rogers S, Scholpp S (2021). Preserving Cytonemes for Immunocytochemistry of Cultured Adherent Cells. In  (Ed) , 183-190. Abstract.  Author URL.
Rogers S, Wong S (2003). C-type lectin and lectin-like receptors in the immune system. In Wong S, Arsequell G (Eds.) Immunobiology of Carbohydrates, Landes Bioscience, 101-118.

Conferences

Rouhi A, Rogers SL, Zhao Y, Eaves CJ, Mager DL (2009). EPIGENETIC MODIFICATIONS CORRELATE WITH EXPRESSION OF THE LEUKEMIC PROGNOSTIC MARKER CD7 IN CHRONIC MYELOID LEUKEMIA.  Author URL.

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Teaching

Fellow of the Higher Education Academy

NSC1003 Foundations in Natural Science

BIO1334 Genetics (Module Convenor)

BIO2066/BIO2068 Forensic Science 

BIO2088 Advanced Cell Biology 

BIO3077 Frontiers in Molecular Cell Biology 

BIO3086 Cell Biology of Disease 

BIOM549 Advanced Lab Skills 

BIO3096 Bioscience Research Project supervisor 

Bioscience Subject Co-ordinator, Flexible Combined Honours

Modules

2023/24


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