Sanjit Chandra Debnath
Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK
My broad research interests are in aquatic microbiology and microbial ecology. Therefore, I have carried out several research projects to investigate the quality of commercial probiotic products used in aquaculture; ecology of disease-causing pathogens in coastal waters of Bangladesh, studied bacterial diversity from various marine and terrestrial-aquatic ecosystems of China, and have discovered several novel bacteria. Thus, I have gained experience in microbial systematics, taxonomy and ecology.
With my growing interest in microbiology, I have joined Professor Charles Tyler’s research group where I will be investigating the microbial shift in cultured tilapia, interaction between the microorganism and their hosts to predict possible disease outbreak and develop strategies to minimize the economic losses may cause by disease outbreaks.
2016 – 2019 MSc in Marine Science (Majoring Marine Microbiology), Zhejiang University, China
2013 – 2014 MSc in Marine Science, University of Chittagong, Bangladesh
2009 – 2013 BSc (Hon’s) in Marine Science, University of Chittagong, Bangladesh
Research group links
Project Title: Understanding microbiomes in cultured tilapia for disease prediction and mitigation strategies
Supervisors: Professor Charles Tyler, Dr Ben Temperton, David Bass (Cefas), Chadag Vishnumurthy Mohan (WorldFish) and Jérôme Delamare-Deboutteville (WorldFish)
Funding Body: WorldFish, University of Exeter
Aquaculture is one of the major and important sectors to global food security, especially in low-income and food-deficit countries like Bangladesh, where it significantly contributes to poverty alleviation. Among various aquaculture species, tilapia are the second most important species farmed globally. Currently, more than 120 countries in the world have introduced various species of tilapia in their commercial fish farming system. Thus, the global tilapia aquaculture production annually grew 11% for the last three decades and in 2017, the global tilapia aquaculture production was 5.9 million tonnes, the value of which was approximately USD11 billion. But diseases caused by microbes in aquaculture are causing mass economic losses to this sector. Due to high stocking density and other stresses, disease outbreaks have become more prevalent in tilapia farms globally.
Microbiomes are one of the major components of human and animal health. Factors and stressors inducing microbial community shifts associated with increased disease in humans are known but very little is known regarding the factors responsible for inducing microbiomes related to fish disease. Microbiomes associated with the host's skin, gill, and gut are likely to provide signals that can be used to study the healthy and disease state of the host.
During this project, I will investigate the microbial communities in the skin and gills of tilapia cultured in Bangladesh aquaculture ponds under various stress conditions and study the shifts of microorganisms to signal for environments conducive for good health and those that signal for impending disease outbreak.
Sharifuzzaman, S.M., Rasid, M.H., Rubby, I.A., Debnath, S.C., Xing, B., Chen, G., Chowdhury, M.S.N., Hossain, M.S. (2021) DNA barcoding confirms a new record of flyingfish Cheilopogon spilonotopterus (Beloniformes: Exocoetidae) from the northern Bay of Bengal. Conservation Genet. Resourc. doi:https://doi.org/10.1007/s12686-021-01200-z
Khan, I., Xie, W.L., Yu, Y.C., Sheng, H., Xu, Y., Wang, J.Q., Debnath, S.C., Xu, J.Z., Zheng, D.Q., Ding, W.J., Wang, P.M. (2020) Heteroexpression of Aspergillus nidulans laeA in Marine-Derived Fungi Triggers Upregulation of Secondary Metabolite Biosynthetic Genes. Mar. Drugs 18 (12), 652. doi:https://doi.org/10.3390/md18120652
Khan, I., Debnath, S.C., Yan, C., Chen, C., Xu, Y., Wang, W.-J., Yu, Y.-C., Zheng, D.-Q., Xu, J.-Z., Wang, P.-M. (2020) Flavobacterium ajazii sp. nov., Isolated from Seaweed of Gouqi Island, China. Curr. Microbiol. 77 (10), 2925-2932. doi:https://doi.org/10.1007/s00284-020-02112-1
Debnath, S.C., Chen, C., Khan, I., Wang, W.J., Zheng, D.Q., Xu, J.Z., Wang, P.M. (2020) Flavobacterium salilacus sp. nov., isolated from surface water of a hypersaline lake, and descriptions of Flavobacterium salilacus subsp. altitudinum subsp. nov. and Flavobacterium salilacus subsp. salilacus subsp. nov. Int. J. Syst. Evol. Microbiol. 70 (7), 4250-4260. doi:https://doi.org/10.1099/ijsem.0.004281
Debnath, S.C., Miyah, A.M.A., Chen, C., Sheng, H., Xu, X.W., Wu, Y.H., Zheng, D.Q., Xu, J.Z., Di, Y.N., Wang, P.M., Shen, L. (2019) Flavobacterium zhairuonensis sp. nov., a gliding bacterium isolated from marine sediment of the East China Sea. J. Microbiol. 57 (12), 1065-1072. doi:https://doi.org/10.1007/s12275-019-9194-4
Debnath, S.C., Chen, C., Liu, S.X., Di, Y.N., Zheng, D.Q., Li, X.Y., Xu, X.W., Xu, J.Z., Wang, P.M. (2019) Flavobacterium sharifuzzamanii sp. nov., Isolated from the Sediments of the East China Sea. Curr. Microbiol. 76 (3), 297-303. doi:https://doi.org/10.1007/s00284-018-1609-7
Chen, C., Ye, Y., Wang, R., Zhang, Y., Wu, C., Debnath, S.C., Ma, Z., Wang, J., Wu, M. (2018) Streptomyces nigra sp. nov. Is a Novel Actinobacterium Isolated From Mangrove Soil and Exerts a Potent Antitumor Activity in Vitro. Front Microbiol 9, 1587. doi:https://doi.org/10.3389/fmicb.2018.01587