Journal articles
Estell C, Davidson L, Eaton JD, Kimura H, Gold VAM, West S (2023). A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription.
Mol Cell,
83(13), 2222-2239.e5.
Abstract.
Author URL.
Rodríguez-Molina JB, West S, Passmore LA (2023). Knowing when to stop: Transcription termination on protein-coding genes by eukaryotic RNAPII.
Mol Cell,
83(3), 404-415.
Abstract.
Author URL.
Jenkins BH, Maguire F, Leonard G, Eaton JD, West S, Housden BE, Milner DS, Richards TA (2021). Characterization of the RNA-interference pathway as a tool for reverse genetic analysis in the nascent phototrophic endosymbiosis, <i>Paramecium bursaria</i>.
ROYAL SOCIETY OPEN SCIENCE,
8(4).
Author URL.
Jenkins BH, Maguire F, Leonard G, Eaton JD, West S, Housden BE, Milner DS, Richards TA (2021). Emergent RNA–RNA interactions can promote stability in a facultative phototrophic endosymbiosis.
Proceedings of the National Academy of Sciences,
118(38).
Abstract.
Estell C, Davidson L, Steketee PC, Monier A, West S (2021). ZC3H4 restricts non-coding transcription in human cells.
Abstract.
Estell C, Davidson L, Steketee PC, Monier A, West S (2021). ZC3H4 restricts non-coding transcription in human cells.
Elife,
10 Abstract.
Author URL.
Eaton JD, Francis L, Davidson L, West S (2020). A unified allosteric/torpedo mechanism for transcriptional termination on human protein-coding genes.
Genes Dev,
34(1-2), 132-145.
Abstract.
Author URL.
Davidson L, Francis L, Eaton JD, West S (2020). Integrator-Dependent and Allosteric/Intrinsic Mechanisms Ensure Efficient Termination of snRNA Transcription.
Cell Rep,
33(4).
Abstract.
Author URL.
Eaton JD, West S (2020). Termination of Transcription by RNA Polymerase II: BOOM!.
Trends in Genetics,
36(9), 664-675.
Abstract.
Davidson L, Francis L, Cordiner RA, Eaton JD, Estell C, Macias S, Cáceres JF, West S (2019). Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control.
Cell Reports,
26(10), 2779-2791.e5.
Abstract.
Eaton JD, West S (2018). An end in sight? Xrn2 and transcriptional termination by RNA polymerase II.
Transcription,
9(5), 321-326.
Abstract.
Author URL.
Eaton JD, Davidson L, Bauer DLV, Natsume T, Kanemaki MT, West S (2018). Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity.
Genes Dev,
32(2), 127-139.
Abstract.
Author URL.
Muniz L, Davidson L, West S (2015). Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs.
MOLECULAR AND CELLULAR BIOLOGY,
35(13), 2218-2230.
Author URL.
Davidson L, Muniz L, West S (2014). 3′ end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells.
GENES & DEVELOPMENT,
28(4), 342-356.
Author URL.
Hett A, West S (2014). Inhibition of U4 snRNA in Human Cells Causes the Stable Retention of Polyadenylated Pre-mRNA in the Nucleus.
PLOS ONE,
9(5).
Author URL.
Davidson L, West S (2013). Splicing-coupled 3' end formation requires a terminal splice acceptor site, but not intron excision.
NUCLEIC ACIDS RESEARCH,
41(14), 7101-7114.
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Davidson L, Kerr A, West S (2012). Co-transcriptional degradation of aberrant pre-mRNA by Xrn2.
EMBO JOURNAL,
31(11), 2566-2578.
Author URL.
West S (2012). The increasing functional repertoire of U1 snRNA.
BIOCHEMICAL SOCIETY TRANSACTIONS,
40, 846-849.
Author URL.
Schmidt M-J, West S, Norbury CJ (2011). The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation.
RNA,
17(1), 39-44.
Author URL.
West S, Proudfoot NJ (2009). Transcriptional Termination Enhances Protein Expression in Human Cells.
MOLECULAR CELL,
33(3), 354-364.
Author URL.
West S, Proudfoot NJ (2008). Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.
NUCLEIC ACIDS RESEARCH,
36(3), 905-914.
Author URL.
West S, Proudfoot NJ, Dye MJ (2008). Molecular dissection of mammalian RNA polymerase II transcriptional termination.
MOLECULAR CELL,
29(5), 600-610.
Author URL.
West S, Gromak N, Norbury CJ, Proudfoot NJ (2006). Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells.
MOLECULAR CELL,
21(3), 437-443.
Author URL.
Gromak N, West S, Proudfoot NJ (2006). Pause sites promote transcriptional termination of mammalian RNA polymerase II.
MOLECULAR AND CELLULAR BIOLOGY,
26(10), 3986-3996.
Author URL.
West S, Zaret K, Proudfoot NJ (2006). Transcriptional termination sequences in the mouse serum albumin gene.
RNA,
12(4), 655-665.
Abstract.
Author URL.
Dye MJ, Gromak N, Haussecker D, West S, Proudfoot NJ (2006). Turnover and function of noncoding RNA polymerase II transcripts.
Cold Spring Harb Symp Quant Biol,
71, 275-284.
Abstract.
Author URL.
Teixeira A, Tahiri-Alaoui A, West S, Thomas B, Ramadass A, Martianov I, Dye M, James W, Proudfoot NJ, Akoulitchev A, et al (2004). Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination.
Nature,
432(7016), 526-530.
Abstract.
Author URL.
West S, Gromak N, Proudfoot NJ (2004). Human 5′→3′ exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites.
NATURE,
432(7016), 522-525.
Author URL.