Alison Hill&refresh | Biosciences | University of Exeter

Dr Alison Hill

Associate Professor (Chemistry and Biochemistry)

A.M.Hill@exeter.ac.uk

4605

Geoffrey Pope 419

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

MSc/MRes Advanced Biological Sciences Programme Director
Senior Tutor for Postgraduate Taught and MSci students
Senior Fellow of the HEA
Exeter Education Incubator Fellow (2017/18; 2022/23, 2023/24)
Royal Society of Chemistry Excellence in Higher Education Prize 2022
LearnSci Teaching Innovation Award 2022, 2023

Qualifications

1994 PhD Bio-organic Chemistry, University of Cambridge
1989 BSc (Hons) Chemistry, Australian National University, Canberra, Australia

Career

2023-present Associate Professor, Department of Biosciences, University of Exeter

2010-2023 Senior Lecturer, Department of Biosciences, University of Exeter
2005-2012 Teaching Fellow, School of Biosciences, University of Exeter
2001-2005 Research Fellow, School of Chemistry, University of Exeter
1995-2001 Lecturer, Department of Chemistry, King's College London
1994-1995 Postdoctoral Researcher, Department of Chemistry, Brown University, Rhode Island, USA

Research group links

Cellular and Chemical Biology

Research

Research interests

I am currently researching using unique data sets for fair and robust examinations:

https://www.timeshighereducation.com/campus/online-exams-are-growing-popularity-how-can-they-be-fair-and-robust

I have done reasearch addressing the Mathematics gap in Biosciences as part of my Exeter Education Incubator project.

https://uofeacademicpracticenetwork.wordpress.com/2018/04/20/addressing-the-mathematics-gap-in-biosciences-and-beyond/

Research projects

Unique data sets: J. Chem. Educ., 2021, 98(12):4094-4100, https://pubs.acs.org/doi/10.1021/acs.jchemed.1c00853

Publications

Journal articles

Hill AM, Harmer NJ (2023). A Murder Mystery Gamification Session to Consolidate Analytical Biochemical Techniques Learning. JOURNAL OF CHEMICAL EDUCATION, 100(11), 4514-4524. Author URL.

Harmer NJ, Hill AM (2021). Unique Data Sets and Bespoke Laboratory Videos: Teaching and Assessing of Experimental Methods and Data Analysis in a Pandemic. Journal of Chemical Education, 98(12), 4094-4100.

Asakura M, Yoshino K, Hill AM, Kubo Y, Sakai Y, Takano Y (2012). Primary and secondary metabolism regulates lipolysis in appressoria of <i>Colletotrichum orbiculare</i>. FUNGAL GENETICS AND BIOLOGY, 49(11), 967-975. Author URL.

Asakura M, Yoshino K, Hill AM, Kubo Y, Sakai Y, Takano Y (2012). Primary and secondary metabolism regulates lipolysis in appressoria of Colletotrichum orbiculare. Fungal Genetics and Biology, 49(11), 967-975. Abstract.

Goodworth KJ, Herve AC, Stavropoulos E, Herve G, Casades I, Hill AM, Weingarten GG, Tascon RE, Colston MJ, Hailes HC, et al (2011). Synthesis and in vivo biological activity of large-ringed calixarenes against Mycobacterium tuberculosis. TETRAHEDRON, 67(2), 373-382. Abstract.

Hii, K.K. Hill, A.M. (2007). Preparation of macrocyclon analogues: calix[8]arenes with extended polyethylene glycol chains. Tetrahedron, 63, 9947-9959.

Hill AM (2006). The Biosynthesis, Molecular Genetics and Enzymology of the Polyketide‐Derived Metabolites. ChemInform, 37(29), no-no.

Hill, A.M. (2006). The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites. Natural Product Reports, 23(2), 256-320.

Hailes, H.C. Hill, A.M. (2004). Antimycobacterial calixarenes enhance innate defense mechanisms in murine macrophages and induce control of Mycobacterium tuberculosis infection in mice. Infection and Immunity, 72(11), 6318-6323.

Louiseau, F.A. Hii, K.K. & Hill, A.M. (2004). Multigram synthesis of well-defined extended bifunctional polyethylene glycol (PEG) chains. Journal of Organic Chemistry, 69(3), 639-647.

Hill, A.M. (2003). A highly efficient synthesis of [1-C-13, O-18]- and [1-C-13, H-2(2)]-glycerol for the elucidation of biosynthetic pathways. Tetrahedron Letters, 44(4), 789-792.

Thompson, B.L. Harris, J.P. Siskos, A.P. (2003). Investigation of the early stages in soraphen a biosynthesis. Chemical Communications, 12, 1358-1359.

Thompson, B.L. (2003). Novel soraphens from precursor directed biosynthesis. Chemical Communications, 12, 1360-1361.

Hahn, D.U. Herve, A.C. Goodworth, K.J. (2003). The selective functionalisation and difunctionalisation of p-substituted calix[6]arene and calix[8]arenes using hydrophilic moieties. Organic and Biomolecular Chemistry, 1(2), 427-435.

Harris, J.P. Siskos, A.P. (1998). Investigation of glycerol incorporation into soraphen A. Chemical Communications, 21, 2361-2362.

Cane, D.E. JD, C. Mau, C.A. (1996). High level expression of Ricinus communis casbene synthase in Escherichia coli and characterization of the recombinant enzyme. Archives of Biochemistry & Biophysics, 336(2), 283-289.

Chapters

Hill AM (2012). Polyketide Polyethers. In (Ed) Natural Products in Chemical Biology, 189-207.

Hill AM, Staunton J (2010). 1.10 Type I Modular PKS. In (Ed) Comprehensive Natural Products II, Elsevier, 385-452.

Hill AM, Staunton JS (2010). Modular Polyketide Synthases. In Mander L, Townsend C (Eds.) Comprehensive Natural Products II: Chemistry and Biology, Elsevier. Abstract.

Hill AM, Staunton, J (2010). Proposed Quaternary Structure of Type I (Modular) Polyketide Synthases. In Wrigley, SK, Thomas, R, Bedford, CT, Nicholson N (Eds.) Functional Molecules from Natural Sources, Cambridge: RSC, 195-208.

Hill AM, Staunton J (2010). Type I modular PKS. In (Ed) Comprehensive Natural Products II: Chemistry and Biology, 385-452.

Hill AM (2009). Polyketide Biosynthesis, Polyethers. In Begley TP (Ed) Wiley Encycopedia of Chemical Biology, Wiley, 760-771. Abstract.

Conferences

Hill AM, Staunton JS (2010). ÝProposed Quaternary Structure of Type I (Modular) Polyketide Synthases. Functional Molecules from Natural Sources. 6th - 8th Jul 2009.

External Engagement and Impact

Awards/Honorary fellowships

Royal Society of Chemistry Excellence in Higher Education Prize 2022

LearnSci Teaching innovation Award 2022, 2023

Most Supportive Member of Staff Bioscience 2012; shortlisted for Exeter Teaching Awards 2012 in this category

Committee/panel activities

RSC Higher Education group

RSC Education Prize committee

RSC Pennisula Group

Editorial responsibilities

Journal of Chemical Education reviewer

Invited lectures

University of Surrey (November 2023)

Queen Mary University of London (November 2023)

University of Reading (January 2024)

University of Plymouth (February 2024)

University of Edinburgh, University of St Andrews, University of Glasgow (April 2024)

University of Bristol (April 2024)

University of Kent (May 2024)

Westminster Higher Education Forum Policy Conference: Next Steps for Tackling Cheating in Higher Education, April 2022

Addressing the Mathematics Gap in Biosciences, Enhancing Student Learning Through Innovative Scholarship Conference, University of Bristol 2018

Variety in Chemical Education/Physics Higher Education Conference (ViCEPHEC), Durham 2023

Teaching

Senior Fellow of the Higher Education Academy
Programme Lead for MSc/MRes Advanced Biological Sciences
Senior Tutor, Postgraduate Taught and MSci Students

Module Coordinator:

BIO2090 Analytical Techniques in Biochemistry
BIO3041 Pharmacology and Medicinal Chemistry
BIO3090 Secondary Metabolism and Metabolites
BIOM509 Professional Skills
BIOM550 Research Project 1
BIOM560 Research Project