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Dr Karen Moore

Dr Karen Moore

Experimental Officer - Exeter Sequencing Service

 6203

 Geoffrey Pope 313

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Overview

I am a molecular biologist with a background in DNA replication and its integration with the cell cycle in plants and yeasts. I have worked on molecular and synthetic biology approaches in biofuels production where I focused on algal bacterial consortia. Currently, I work for Exeter Sequencing Service where I aim to develop next generation genetic approaches to enable improved understanding of genomic models.

Broad research specialisms

In the rapidly evolving field of genomics my aim is to assist scientists perform up to date quality experiments in a cost efficient manner. Three areas are important: first, optimization of routine NGS library preparation protocols including controls and using sequencing metrics to improve service delivery; second, to develop custom designed functional genomics assays for a wide range of aims and objectives and third, to provide training and consultancy to enable a successful genomics projects from start to end (including planning, sample management, experimental pipelines and bioinformatics analysis). Development of experimental pipelines and bioinformatics analysis is undertaken by Paul O’Neill.

Qualifications

2000    PhD Biological Sciences, University of Exeter, UK

1995    BSc hons Biological Sciences, University of Exeter, UK

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Mill J, Leung SK, Ribarska T, Hannon E, Smith A, Pishva E, Poschmann J, Moore K, Troakes C, Al-Sarraj S, et al (In Press). A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience
Marzi SJ, Ribarska T, Smith AR, Hannon E, Poschmann J, Moore K, Troakes C, Al-Sarraj S, Beck S, Newman S, et al (In Press). A histone acetylome-wide association study of Alzheimer’s disease: neuropathology-associated regulatory variation in the human entorhinal cortex.  Abstract.
Jeffries AR, Leung SK, Castanho I, Moore K, Davies JP, Dempster EL, Bray NJ, O‘Neill P, Tseng E, Ahmed Z, et al (In Press). Full-length transcript sequencing of human and mouse identifies widespread isoform diversity and alternative splicing in the cerebral cortex.  Abstract.
Warwick-Dugdale J, Moore K, Allen M, Temperton B (In Press). Long-read viral metagenomics captures abundant and microdiverse viral populations and their niche-defining genomic islands. PeerJ
Warwick-Dugdale J, Solonenko N, Moore K, Chittick L, Gregory AC, Allen MJ, Sullivan MB, Temperton B (In Press). Long-read viral metagenomics enables capture of abundant and microdiverse viral populations and their niche-defining genomic islands.  Abstract.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (In Press). Transcriptional reprogramming of Trichoderma hamatum GD12 in soil during plant growth promotion and biological control of Sclerotinia sclerotiorum. Environmental Microbiology
Clark GC, Elfsmark L, Armstrong S, Essex-Lopresti A, Gustafsson Å, Ryan Y, Moore K, Paszkiewicz K, Green AC, Hiscox JA, et al (2023). From “crisis to recovery”: a complete insight into the mechanisms of chlorine injury in the lung. Life Sciences, 312, 121252-121252.
Wheildon G, Smith AR, Soanes D, Southern F, Devall M, Moore K, O'Neill P, Troakes C, Lunnon K (2022). DNA methylation of mitochondrial DNA shows variation in human brain. Alzheimer's and Dementia, 18(S4). Abstract.
Glover G, Voliotis M, Łapińska U, Invergo BM, Soanes D, O’Neill P, Moore K, Nikolic N, Petrov PG, Milner DS, et al (2022). Nutrient and salt depletion synergistically boosts glucose metabolism in individual Escherichia coli cells. Communications Biology, 5(1). Abstract.
Millard RS, Bickley LK, Bateman KS, Verbruggen B, Farbos A, Lange A, Moore KA, Stentiford GD, Tyler CR, van Aerle R, et al (2022). Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses. Front Immunol, 13 Abstract.  Author URL.
Wheildon G, Smith AR, Soanes D, Smith RG, Moore K, O'Neill P, Morgan K, Thomas AJ, Francis PT, Love S, et al (2022). Targeted bisulfite sequencing analysis of candidate genes associated with Alzheimer’s disease. Alzheimer's & Dementia, 18(S4).
Cano I, Santos EM, Moore K, Farbos A, van Aerle R (2021). Evidence of Transcriptional Shutoff by Pathogenic Viral Haemorrhagic Septicaemia Virus in Rainbow Trout. Viruses, 13(6). Abstract.  Author URL.
Leung SK, Jeffries AR, Castanho I, Jordan BT, Moore K, Davies JP, Dempster EL, Bray NJ, O’Neill P, Tseng E, et al (2021). Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing. Cell Reports, 37(7), 110022-110022.
Millard RS, Bickley LK, Bateman KS, Farbos A, Minardi D, Moore K, Ross SH, Stentiford GD, Tyler CR, van Aerle R, et al (2021). Global mRNA and miRNA Analysis Reveal Key Processes in the Initial Response to Infection with WSSV in the Pacific Whiteleg Shrimp. VIRUSES-BASEL, 13(6). Author URL.
Hooper L, Jenkins TL, Griffiths AM, Moore KA, Stevens JR (2021). The complete mitochondrial genome of the pink sea fan, <i>Eunicella verrucosa</i> (Pallas, 1766). Mitochondrial DNA Part B, 6(11), 3309-3311.
Ducret V, Richards AJ, Videlier M, Scalvenzi T, Moore KA, Paszkiewicz K, Bonneaud C, Pollet N, Herrel A (2021). Transcriptomic analysis of the trade-off between endurance and burst-performance in the frog Xenopus allofraseri. BMC Genomics, 22(1). Abstract.  Author URL.
Leung SK, Jeffries A, Hannon E, Castanho I, Moore K, Murray TK, Ahmed Z, Collier DA, Mill J (2020). Characterization of mRNA isoform diversity in a transgenic model of tau pathology using targeted long‐read sequencing. Alzheimer's & Dementia, 16(S3).
Viana J, Wildman N, Hannon E, Farbos A, Neill PO, Moore K, van Aerle R, Paull G, Santos E, Mill J, et al (2020). Clozapine-induced transcriptional changes in the zebrafish brain. NPJ Schizophr, 6(1). Abstract.  Author URL.
Rodríguez-Martínez R, Leonard G, Milner DS, Sudek S, Conway M, Moore K, Hudson T, Mahé F, Keeling PJ, Santoro AE, et al (2020). Controlled sampling of ribosomally active protistan diversity in sediment-surface layers identifies putative players in the marine carbon sink. ISME J, 14(4), 984-998. Abstract.  Author URL.
Mittell EA, Cobbold CA, Ijaz UZ, Kilbride EA, Moore KA, Mable BK (2020). Feral populations of Brassica oleracea along Atlantic coasts in western Europe. Ecology and Evolution, 10(20), 11810-11825. Abstract.
Sambles C, Venkatesan L, Shittu OM, Harrison J, Moore K, Tripathi L, Grant M, Warmington R, Studholme DJ (2020). Genome sequencing data for wild and cultivated bananas, plantains and abacá. Data in Brief, 33 Abstract.
Hamilton PB, Lockyer AE, Uren Webster TM, Studholme DJ, Paris JR, Baynes A, Nicol E, Dawson DA, Moore K, Farbos A, et al (2020). Investigation into Adaptation in Genes Associated with Response to Estrogenic Pollution in Populations of Roach (Rutilus rutilus) Living in English Rivers. Environ Sci Technol, 54(24), 15935-15945. Abstract.  Author URL.
Haque S, Ames RM, Moore K, Lee BP, Jeffery N, Harries LW (2020). Islet-expressed circular RNAs are associated with type 2 diabetes status in human primary islets and in peripheral blood. BMC Med Genomics, 13(1). Abstract.  Author URL.
Sherman KD, Paris J, King RA, Moore KA, Dahlgren CP, Knowles LC, Stump K, Tyler CR, Stevens JR (2020). RAD-Seq Analysis and in situ Monitoring of Nassau Grouper Reveal Fine-Scale Population Structure and Origins of Aggregating Fish. FRONTIERS IN MARINE SCIENCE, 7 Author URL.
Chaput DL, Bass D, Alam MM, Al Hasan N, Stentiford GD, van Aerle R, Moore K, Bignell JP, Haque MM, Tyler CR, et al (2020). The Segment Matters: Probable Reassortment of Tilapia Lake Virus (TiLV) Complicates Phylogenetic Analysis and Inference of Geographical Origin of New Isolate from Bangladesh. Viruses, 12(3), 258-258. Abstract.
Castanho I, Murray TK, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Bradshaw L, Randall A, et al (2020). Transcriptional Signatures of Tau and Amyloid Neuropathology. Cell Rep, 30(6), 2040-2054.e5. Abstract.  Author URL.
Mills LJ, Wilson JD, Lange A, Moore K, Henwood B, Knipe H, Chaput DL, Tyler CR (2020). Using molecular and crowd‐sourcing methods to assess breeding ground diet of a migratory brood parasite of conservation concern. Journal of Avian Biology, 51(9).
Haque S, Ames RM, Moore K, Pilling LC, Peters LL, Bandinelli S, Ferrucci L, Harries LW (2020). circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan. Geroscience, 42(1), 183-199. Abstract.  Author URL.
Clark GC, Essex-Lopresti A, Moore KA, Williamson ED, Lukaszewski R, Paszkiewicz K, David J (2019). Common Host Responses in Murine Aerosol Models of Infection Caused by Highly Virulent Gram-Negative Bacteria from the Genera Burkholderia, Francisella and Yersinia. Pathogens, 8(4). Abstract.  Author URL.
Warmington RJ, Kay W, Jeffries A, O'Neill P, Farbos A, Moore K, Bebber DP, Studholme DJ (2019). High-Quality Draft Genome Sequence of the Causal Agent of the Current Panama Disease Epidemic. Microbiol Resour Announc, 8(36). Abstract.  Author URL.
Tennant RK, Lux T, Sambles C, Kuhn N, Petticrew E, Oldfield R, Parker D, Hatton J, Moore K, Lee R, et al (2019). Palaeogenomics of the Hydrocarbon Producing Microalga Botryococcus braunii. Scientific Reports, 9
Castanho I, Murray T, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Randall A, Moore K, et al (2019). Transcriptional Signatures of Progressive Neuropathology in Transgenic Models of Tau and Amyloid Pathology.
Wideman JG, Monier A, Rodríguez-Martínez R, Leonard G, Cook E, Poirier C, Maguire F, Milner DS, Irwin NAT, Moore K, et al (2019). Unexpected mitochondrial genome diversity revealed by targeted single-cell genomics of heterotrophic flagellated protists. Nature Microbiology, 5(1), 154-165.
Flaviani F, Schroeder DC, Lebret K, Balestreri C, Highfield AC, Schroeder JL, Thorpe SE, Moore K, Pasckiewicz K, Pfaff MC, et al (2018). Distinct oceanic microbiomes from viruses to protists located near the Antarctic Circumpolar current. Frontiers in Microbiology, 9(JUL). Abstract.
Yemataw Z, Muzemil S, Ambachew D, Tripathi L, Tesfaye K, Chala A, Farbos A, O'Neill P, Moore K, Grant M, et al (2018). Genome sequence data from 17 accessions of Ensete ventricosum, a staple food crop for millions in Ethiopia. Data in Brief, 18, 285-293. Abstract.
Morcrette H, Morgan MS, Farbos A, O'Neill P, Moore K, Titball RW, Studholme DJ (2018). Genome sequence of Staphylococcus aureus Ex1, isolated from a patient with spinal osteomyelitis. Genome Announcements, 6(26). Abstract.
Castanho IMS, Murray TK, Farbos A, Lunnon K, Collier DA, Ahmed Z, Moore K, O'Neill MJ, Mill J (2018). P3‐123: MAPPING GENOMIC CONSEQUENCES OF ALZHEIMER'S DISEASE PATHOLOGY IN AMYLOID AND TAU MOUSE MODELS. Alzheimer's & Dementia, 14(7S_Part_21), p1114-p1115.
Smith A, Kaczmar A, Bamford RA, Smith C, Frustaci S, Kovacs-Simon A, O'Neill P, Moore K, Paszkiewicz K, Titball RW, et al (2018). The Culture Environment Influences Both Gene Regulation and Phenotypic Heterogeneity in Escherichia coli. FRONTIERS IN MICROBIOLOGY, 9 Author URL.
Yang ZR, Bullifent HL, Moore K, Paszkiewicz K, Saint RJ, Southern SJ, Champion OL, Senior NJ, Sarkar-Tyson M, Oyston PCF, et al (2017). A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis. Sci Rep, 7 Abstract.  Author URL.
Flaviani F, Schroeder DC, Balestreri C, Schroeder JL, Moore K, Paszkiewicz K, Pfaff MC, Rybicki EP (2017). A Pelagic Microbiome (Viruses to Protists) from a Small Cup of Seawater. Viruses, 9(3). Abstract.  Author URL.
Senior NJ, Sasidharan K, Saint RJ, Scott AE, Sarkar-Tyson M, Ireland PM, Bullifent HL, Rong Yang Z, Moore K, Oyston PCF, et al (2017). An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions. BMC Microbiology, 17(1). Abstract.
Wiredu Boakye D, Jaroenlak P, Prachumwat A, Williams TA, Bateman K, Itsathiphaisarn O, Sritunyalucksan K, Paszkiewicz K, Moore KA, Stentiford G, et al (2017). Decay of the glycolytic pathway and adaptation to intranuclear parasitism within Enterocytozoonidae microsporidia. Environmental Microbiology, 19(5), 2077-2089.
Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2.
Dunthorn M, Zufall RA, Chi J, Paszkiewicz K, Moore K, Mahé F (2017). Meiotic Genes in Colpodean Ciliates Support Secretive Sexuality. Genome Biol Evol, 9(6), 1781-1787. Abstract.  Author URL.
Tennant RK, Sambles CM, Diffey GE, Moore KA, Love J (2017). Metagenomic Analysis of Silage. Journal of Visualized Experiments, 119, e54936-e54936.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga<i>Botryococcus braunii</i>. MicrobiologyOpen, 6(4), e00482-e00482.
Mitchelmore PJ, Randall J, Bull MJ, Moore KA, O'Neill PA, Paszkiewicz K, Mahenthiralingam E, Scotton CJ, Sheldon CD, Withers NJ, et al (2017). Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax Abstract.  Author URL.
Williams TA, Nakjang S, Campbell SE, Freeman MA, Eydal M, Moore K, Hirt RP, Embley TM, Williams BAP (2016). A recent whole-genome duplication divides populations of a globally-distributed microsporidian. Molecular Biology and Evolution Abstract.
Gal C, Murton HE, Subramanian L, Whale AJ, Moore KM, Paszkiewicz K, Codlin S, Bähler J, Creamer KM, Partridge JF, et al (2016). Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation. EMBO Rep, 17(1), 79-93. Abstract.  Author URL.
Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.
Laver TW, Caswell RC, Moore KA, Poschmann J, Johnson MB, Owens MM, Ellard S, Paszkiewicz KH, Weedon MN (2016). Pitfalls of haplotype phasing from amplicon-based long-read sequencing. Sci Rep, 6 Abstract.  Author URL.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (2016). Transcriptional reprogramming underpins enhanced plant growth promotion by the biocontrol fungus Trichoderma hamatum GD12 during antagonistic interactions with Sclerotinia sclerotiorum in soil. Molecular Plant Pathology, 17, 1425-1441. Abstract.
Price SJ, Garner TWJ, Balloux F, Ruis C, Paszkiewicz KH, Moore K, Griffiths AGF (2015). A de novo Assembly of the Common Frog (Rana temporaria) Transcriptome and Comparison of Transcription Following Exposure to Ranavirus and Batrachochytrium dendrobatidis. PLoS One, 10(6). Abstract.  Author URL.
Laver T, Harrison J, O'Neill PA, Moore K, Farbos A, Paszkiewicz K, Studholme DJ (2015). Assessing the performance of the Oxford Nanopore Technologies MinION. Biomolecular Detection and Quantification, 3, 1-8. Abstract.
Masood N, Moore K, Farbos A, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2015). Genomic dissection of the 1994 Cronobacter sakazakii outbreak in a French neonatal intensive care unit. BMC Genomics, 16 Abstract.  Author URL.
Uren Webster TM, Shears JA, Moore K, Santos EM (2015). Identification of conserved hepatic transcriptomic responses to 17β-estradiol using high-throughput sequencing in brown trout. Physiol Genomics, 47(9), 420-431. Abstract.  Author URL.
MacGregor DR, Kendall SL, Florance H, Fedi F, Moore K, Paszkiewicz K, Smirnoff N, Penfield S (2015). Seed production temperature regulation of primary dormancy occurs through control of seed coat phenylpropanoid metabolism. New Phytol, 205(2), 642-652. Abstract.  Author URL.
Gal C, Moore KM, Paszkiewicz K, Kent NA, Whitehall SK (2015). The impact of the HIRA histone chaperone upon global nucleosome architecture. Cell Cycle, 14(1), 123-134. Abstract.  Author URL.
Alkeskas A, Ogrodzki P, Saad M, Masood N, Rhoma NR, Moore K, Farbos A, Paszkiewicz K, Forsythe S (2015). The molecular characterisation of Escherichia coli K1 isolated from neonatal nasogastric feeding tubes. BMC Infect Dis, 15 Abstract.  Author URL.
Watson AK, Williams TA, Williams BAP, Moore KA, Hirt RP, Embley TM (2015). Transcriptomic profiling of host-parasite interactions in the microsporidian Trachipleistophora hominis. BMC Genomics Abstract.
Harrison J, Moore K, Paszkiewicz K, Jones T, Grant M, Ambacheew D, Muzemil S, Studholme D (2014). A Draft Genome Sequence for Ensete ventricosum, the Drought-Tolerant “Tree Against Hunger”. Agronomy, 4, 13-33. Abstract.
Heintzman PD, Elias SA, Moore K, Paszkiewicz K, Barnes I (2014). Characterizing DNA preservation in degraded specimens of Amara alpina (Carabidae: Coleoptera). Mol Ecol Resour, 14(3), 606-615. Abstract.  Author URL.
Masood N, Jackson E, Moore K, Farbos A, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2014). Draft Genome Sequence of "Candidatus Cronobacter colletis" NCTC 14934T, a New Species in the Genus Cronobacter. Genome Announc, 2(3). Abstract.  Author URL.
Bertolini C, van Aerle R, Lampis S, Moore KA, Paszkiewicz K, Butler CS, Vallini G, van der Giezen M (2014). Draft Genome Sequence of Stenotrophomonas maltophilia SeITE02, a Gammaproteobacterium Isolated from Selenite-Contaminated Mining Soil. Genome Announc, 2(3). Abstract.  Author URL.
Chen M, MacGregor DR, Dave A, Florance H, Moore K, Paszkiewicz K, Smirnoff N, Graham IA, Penfield S (2014). Maternal temperature history activates Flowering Locus T in fruits to control progeny dormancy according to time of year. Proc Natl Acad Sci U S A, 111(52), 18787-18792. Abstract.  Author URL.
Paszkiewicz KH, Farbos A, O'Neill P, Moore K (2014). Quality control on the frontier. Front Genet, 5 Abstract.  Author URL.
Milne SW, Cheetham J, Lloyd D, Shaw S, Moore K, Paszkiewicz KH, Aves SJ, Bates S (2014). Role of Candida albicans Tem1 in mitotic exit and cytokinesis. Fungal Genet Biol, 69, 84-95. Abstract.  Author URL.
Maruyama H, Harwood JC, Moore KM, Paszkiewicz K, Durley SC, Fukushima H, Atomi H, Takeyasu K, Kent NA (2013). An alternative beads-on-a-string chromatin architecture in Thermococcus kodakarensis. EMBO Rep, 14(8), 711-717. Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Block C, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft Genome Sequence of a Meningitic Isolate of Cronobacter sakazakii Clonal Complex 4, Strain 8399. Genome Announc, 1(5). Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft Genome Sequence of the Earliest Cronobacter sakazakii Sequence Type 4 Strain, NCIMB 8272. Genome Announc, 1(5). Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft Genome Sequences of Three Newly Identified Species in the Genus Cronobacter, C. helveticus LMG23732T, C. pulveris LMG24059, and C. zurichensis LMG23730T. Genome Announc, 1(5). Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Block C, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft genome sequence of a meningitic isolate of Cronobacter sakazakii clonal complex 4, strain 8399. Genome Announcements, 1(5). Abstract.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft genome sequence of the earliest Cronobacter sakazakii sequence type 4 strain, NCIMB 8272. Genome Announcements, 1(5). Abstract.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft genome sequences of three newly identified species in the genus Cronobacter, C. helveticus LMG23732<sup>T</sup>, C. pulveris LMG24059, and C. zurichensis LMG23730<sup>T</sup>. Genome Announcements, 1(5). Abstract.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA -directed DNA methylation. Plant Journal, 75(5), 836-846. Abstract.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA-directed DNA methylation. Plant Journal
Taylor M, Moore K, Murray J, Aves SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10(11), 1154-1163.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2003). The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002). NATURE, 421(6918), 94-94. Author URL.
Hart EA, Bryant JA, Moore K, Aves SJ (2002). Fission yeast Cdc23 interactions with DNA replication initiation proteins. Curr Genet, 41(5), 342-348. Abstract.  Author URL.
Aves SJ, Gwilliam R, Wood V, Xiang Z (2002). The genome sequence of Schizosaccharomyces pombe. Nature, 415(6874), 871-880.
Moore, K. Aves, S.J. (2001). Origins and complexes: the initiation of DNA replication. Journal of Experimental Botany, 52, 193-202.
Hunt C, Moore K, Xiang Z, Hurst SM, McDougall RC, Rajandream MA, Barrell BG, Gwilliam R, Wood V, Lyne MH, et al (2001). Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes. Yeast, 18(4), 355-361. Abstract.  Author URL.
Xiang Z, Moore K, Wood V, Rajandream MA, Barrell BG, Skelton J, Churcher CM, Lyne MH, Devlin K, Gwilliam R, et al (2000). Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5. Yeast, 16(15), 1405-1411. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). Current awareness on yeast. Yeast, 16(11), 1069-1076. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). Identification of a Candida albicans homologue of the PHO85 gene, a negative regulator of the PHO system in Saccharomyces cerevisiae. Yeast, 16(11), 1045-1051. Abstract.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). The mating-type region of Schizosaccharomyces pombe h(-S) 972: Sequencing and analysis of 69 kb including the expressed matl locus. Yeast, 16(11), 1061-1067. Abstract.
Munns MS, Moore K, Jossé L, Fitchett PN, Bryant JA (1998). The use of a multiple antigen peptide to detect a minichromosome maintenance protein in pea (Pisum sativum). Experimental Biology Online, 3(7), 1-5.
Talbot NJ, McCafferty HRK, Ma M, Moore K, Hamer JE (1997). Nitrogen starvation of the rice blast fungus Magnaporthe grisea may act as an environmental cue for disease symptom expression. PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 50(3), 179-195. Author URL.

Chapters

Moore, K. Aves, S.J. (2008). Mcm10 and DNA replication in fission yeast. In Bryant J, Francis D (Eds.) The Eukaryotic Cell Cycle, Taylor & Francis, 45-69.
Munns MS, Moore K, Jossé L, Fitchett PN, Bryant JA (1999). The use of a multiple antigen peptide to detect a minichromosome maintenance protein in pea (Pisum sativum). In  (Ed) EBO Experimental Biology Online Annual 1998, 89-95.

Conferences

Viana J, Wildman N, Hannon E, Farbos A, O'Neill P, Moore K, Paszkiewicz K, van Aerle R, Paull G, Santos E, et al (2019). A ZEBRAFISH MODEL OF CLOZAPINE EXPOSURE: DRUG-INDUCED TRANSCRIPTOMIC CHANGES IN THE BRAIN.  Author URL.
Essex-Lopresti A, David J, Moore K, Armstrong S, Auton P, Rutter S, Green C, Hiscox JA, Paszkiewicz KH, Clark GC, et al (2019). UNBIASED WHOLE GENOME SEQUENCE ANALYSIS OF THE MURINE TRANSCRIPTOME IN RESPONSE TO RICIN EXPOSURE VIA THE PULMONARY ROUTE.  Author URL.

Publications by year


In Press

Mill J, Leung SK, Ribarska T, Hannon E, Smith A, Pishva E, Poschmann J, Moore K, Troakes C, Al-Sarraj S, et al (In Press). A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience
Marzi SJ, Ribarska T, Smith AR, Hannon E, Poschmann J, Moore K, Troakes C, Al-Sarraj S, Beck S, Newman S, et al (In Press). A histone acetylome-wide association study of Alzheimer’s disease: neuropathology-associated regulatory variation in the human entorhinal cortex.  Abstract.
Jeffries AR, Leung SK, Castanho I, Moore K, Davies JP, Dempster EL, Bray NJ, O‘Neill P, Tseng E, Ahmed Z, et al (In Press). Full-length transcript sequencing of human and mouse identifies widespread isoform diversity and alternative splicing in the cerebral cortex.  Abstract.
Warwick-Dugdale J, Tian F, Michelsen M, Cronin DR, Moore K, Farbos A, Chittick L, Bell A, Buchholz HH, Parsons RJ, et al (In Press). Long-read powered viral metagenomics in the Oligotrophic Sargasso Sea.  Abstract.
Warwick-Dugdale J, Moore K, Allen M, Temperton B (In Press). Long-read viral metagenomics captures abundant and microdiverse viral populations and their niche-defining genomic islands. PeerJ
Warwick-Dugdale J, Solonenko N, Moore K, Chittick L, Gregory AC, Allen MJ, Sullivan MB, Temperton B (In Press). Long-read viral metagenomics enables capture of abundant and microdiverse viral populations and their niche-defining genomic islands.  Abstract.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (In Press). Transcriptional reprogramming of Trichoderma hamatum GD12 in soil during plant growth promotion and biological control of Sclerotinia sclerotiorum. Environmental Microbiology

2023

Clark GC, Elfsmark L, Armstrong S, Essex-Lopresti A, Gustafsson Å, Ryan Y, Moore K, Paszkiewicz K, Green AC, Hiscox JA, et al (2023). From “crisis to recovery”: a complete insight into the mechanisms of chlorine injury in the lung. Life Sciences, 312, 121252-121252.

2022

Wheildon G, Smith AR, Soanes D, Southern F, Devall M, Moore K, O'Neill P, Troakes C, Lunnon K (2022). DNA methylation of mitochondrial DNA shows variation in human brain. Alzheimer's and Dementia, 18(S4). Abstract.
Glover G, Voliotis M, Łapińska U, Invergo BM, Soanes D, O’Neill P, Moore K, Nikolic N, Petrov PG, Milner DS, et al (2022). Nutrient and salt depletion synergistically boosts glucose metabolism in individual Escherichia coli cells. Communications Biology, 5(1). Abstract.
Glover G, Voliotis M, Łapińska U, Invergo BM, Soanes D, O’Neill P, Moore K, Nikolic N, Petrov PG, Milner DS, et al (2022). Nutrient and salt depletion synergistically boosts glucose metabolism in individual bacteria.
Millard RS, Bickley LK, Bateman KS, Verbruggen B, Farbos A, Lange A, Moore KA, Stentiford GD, Tyler CR, van Aerle R, et al (2022). Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses. Front Immunol, 13 Abstract.  Author URL.
Wheildon G, Smith AR, Soanes D, Smith RG, Moore K, O'Neill P, Morgan K, Thomas AJ, Francis PT, Love S, et al (2022). Targeted bisulfite sequencing analysis of candidate genes associated with Alzheimer’s disease. Alzheimer's & Dementia, 18(S4).

2021

Cano I, Santos EM, Moore K, Farbos A, van Aerle R (2021). Evidence of Transcriptional Shutoff by Pathogenic Viral Haemorrhagic Septicaemia Virus in Rainbow Trout. Viruses, 13(6). Abstract.  Author URL.
Leung SK, Jeffries AR, Castanho I, Jordan BT, Moore K, Davies JP, Dempster EL, Bray NJ, O’Neill P, Tseng E, et al (2021). Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing. Cell Reports, 37(7), 110022-110022.
Millard RS, Bickley LK, Bateman KS, Farbos A, Minardi D, Moore K, Ross SH, Stentiford GD, Tyler CR, van Aerle R, et al (2021). Global mRNA and miRNA Analysis Reveal Key Processes in the Initial Response to Infection with WSSV in the Pacific Whiteleg Shrimp. VIRUSES-BASEL, 13(6). Author URL.
Hooper L, Jenkins TL, Griffiths AM, Moore KA, Stevens JR (2021). The complete mitochondrial genome of the pink sea fan, <i>Eunicella verrucosa</i> (Pallas, 1766). Mitochondrial DNA Part B, 6(11), 3309-3311.
Ducret V, Richards AJ, Videlier M, Scalvenzi T, Moore KA, Paszkiewicz K, Bonneaud C, Pollet N, Herrel A (2021). Transcriptomic analysis of the trade-off between endurance and burst-performance in the frog Xenopus allofraseri. BMC Genomics, 22(1). Abstract.  Author URL.

2020

Leung SK, Jeffries A, Hannon E, Castanho I, Moore K, Murray TK, Ahmed Z, Collier DA, Mill J (2020). Characterization of mRNA isoform diversity in a transgenic model of tau pathology using targeted long‐read sequencing. Alzheimer's & Dementia, 16(S3).
Viana J, Wildman N, Hannon E, Farbos A, Neill PO, Moore K, van Aerle R, Paull G, Santos E, Mill J, et al (2020). Clozapine-induced transcriptional changes in the zebrafish brain. NPJ Schizophr, 6(1). Abstract.  Author URL.
Rodríguez-Martínez R, Leonard G, Milner DS, Sudek S, Conway M, Moore K, Hudson T, Mahé F, Keeling PJ, Santoro AE, et al (2020). Controlled sampling of ribosomally active protistan diversity in sediment-surface layers identifies putative players in the marine carbon sink. ISME J, 14(4), 984-998. Abstract.  Author URL.
Mittell EA, Cobbold CA, Ijaz UZ, Kilbride EA, Moore KA, Mable BK (2020). Feral populations of Brassica oleracea along Atlantic coasts in western Europe. Ecology and Evolution, 10(20), 11810-11825. Abstract.
Sambles C, Venkatesan L, Shittu OM, Harrison J, Moore K, Tripathi L, Grant M, Warmington R, Studholme DJ (2020). Genome sequencing data for wild and cultivated bananas, plantains and abacá. Data in Brief, 33 Abstract.
Hamilton PB, Lockyer AE, Uren Webster TM, Studholme DJ, Paris JR, Baynes A, Nicol E, Dawson DA, Moore K, Farbos A, et al (2020). Investigation into Adaptation in Genes Associated with Response to Estrogenic Pollution in Populations of Roach (Rutilus rutilus) Living in English Rivers. Environ Sci Technol, 54(24), 15935-15945. Abstract.  Author URL.
Haque S, Ames RM, Moore K, Lee BP, Jeffery N, Harries LW (2020). Islet-expressed circular RNAs are associated with type 2 diabetes status in human primary islets and in peripheral blood. BMC Med Genomics, 13(1). Abstract.  Author URL.
Sherman KD, Paris J, King RA, Moore KA, Dahlgren CP, Knowles LC, Stump K, Tyler CR, Stevens JR (2020). RAD-Seq Analysis and in situ Monitoring of Nassau Grouper Reveal Fine-Scale Population Structure and Origins of Aggregating Fish. FRONTIERS IN MARINE SCIENCE, 7 Author URL.
Chaput DL, Bass D, Alam MM, Al Hasan N, Stentiford GD, van Aerle R, Moore K, Bignell JP, Haque MM, Tyler CR, et al (2020). The Segment Matters: Probable Reassortment of Tilapia Lake Virus (TiLV) Complicates Phylogenetic Analysis and Inference of Geographical Origin of New Isolate from Bangladesh. Viruses, 12(3), 258-258. Abstract.
Castanho I, Murray TK, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Bradshaw L, Randall A, et al (2020). Transcriptional Signatures of Tau and Amyloid Neuropathology. Cell Rep, 30(6), 2040-2054.e5. Abstract.  Author URL.
Mills LJ, Wilson JD, Lange A, Moore K, Henwood B, Knipe H, Chaput DL, Tyler CR (2020). Using molecular and crowd‐sourcing methods to assess breeding ground diet of a migratory brood parasite of conservation concern. Journal of Avian Biology, 51(9).
Haque S, Ames RM, Moore K, Pilling LC, Peters LL, Bandinelli S, Ferrucci L, Harries LW (2020). circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan. Geroscience, 42(1), 183-199. Abstract.  Author URL.

2019

Viana J, Wildman N, Hannon E, Farbos A, O'Neill P, Moore K, Paszkiewicz K, van Aerle R, Paull G, Santos E, et al (2019). A ZEBRAFISH MODEL OF CLOZAPINE EXPOSURE: DRUG-INDUCED TRANSCRIPTOMIC CHANGES IN THE BRAIN.  Author URL.
Clark GC, Essex-Lopresti A, Moore KA, Williamson ED, Lukaszewski R, Paszkiewicz K, David J (2019). Common Host Responses in Murine Aerosol Models of Infection Caused by Highly Virulent Gram-Negative Bacteria from the Genera Burkholderia, Francisella and Yersinia. Pathogens, 8(4). Abstract.  Author URL.
Warmington RJ, Kay W, Jeffries A, O'Neill P, Farbos A, Moore K, Bebber DP, Studholme DJ (2019). High-Quality Draft Genome Sequence of the Causal Agent of the Current Panama Disease Epidemic. Microbiol Resour Announc, 8(36). Abstract.  Author URL.
Tennant RK, Lux T, Sambles C, Kuhn N, Petticrew E, Oldfield R, Parker D, Hatton J, Moore K, Lee R, et al (2019). Palaeogenomics of the Hydrocarbon Producing Microalga Botryococcus braunii. Scientific Reports, 9
Castanho I, Murray T, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Randall A, Moore K, et al (2019). Transcriptional Signatures of Progressive Neuropathology in Transgenic Models of Tau and Amyloid Pathology.
Castanho I, Murray T, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Randall A, Moore K, et al (2019). Transcriptional Signatures of Progressive Neuropathology in Transgenic Models of Tau and Amyloid Pathology.
Essex-Lopresti A, David J, Moore K, Armstrong S, Auton P, Rutter S, Green C, Hiscox JA, Paszkiewicz KH, Clark GC, et al (2019). UNBIASED WHOLE GENOME SEQUENCE ANALYSIS OF THE MURINE TRANSCRIPTOME IN RESPONSE TO RICIN EXPOSURE VIA THE PULMONARY ROUTE.  Author URL.
Wideman JG, Monier A, Rodríguez-Martínez R, Leonard G, Cook E, Poirier C, Maguire F, Milner DS, Irwin NAT, Moore K, et al (2019). Unexpected mitochondrial genome diversity revealed by targeted single-cell genomics of heterotrophic flagellated protists. Nature Microbiology, 5(1), 154-165.

2018

Flaviani F, Schroeder DC, Lebret K, Balestreri C, Highfield AC, Schroeder JL, Thorpe SE, Moore K, Pasckiewicz K, Pfaff MC, et al (2018). Distinct oceanic microbiomes from viruses to protists located near the Antarctic Circumpolar current. Frontiers in Microbiology, 9(JUL). Abstract.
Yemataw Z, Muzemil S, Ambachew D, Tripathi L, Tesfaye K, Chala A, Farbos A, O'Neill P, Moore K, Grant M, et al (2018). Genome sequence data from 17 accessions of Ensete ventricosum, a staple food crop for millions in Ethiopia. Data in Brief, 18, 285-293. Abstract.
Morcrette H, Morgan MS, Farbos A, O'Neill P, Moore K, Titball RW, Studholme DJ (2018). Genome sequence of Staphylococcus aureus Ex1, isolated from a patient with spinal osteomyelitis. Genome Announcements, 6(26). Abstract.
Castanho IMS, Murray TK, Farbos A, Lunnon K, Collier DA, Ahmed Z, Moore K, O'Neill MJ, Mill J (2018). P3‐123: MAPPING GENOMIC CONSEQUENCES OF ALZHEIMER'S DISEASE PATHOLOGY IN AMYLOID AND TAU MOUSE MODELS. Alzheimer's & Dementia, 14(7S_Part_21), p1114-p1115.
Smith A, Kaczmar A, Bamford RA, Smith C, Frustaci S, Kovacs-Simon A, O'Neill P, Moore K, Paszkiewicz K, Titball RW, et al (2018). The Culture Environment Influences Both Gene Regulation and Phenotypic Heterogeneity in Escherichia coli. FRONTIERS IN MICROBIOLOGY, 9 Author URL.

2017

Yang ZR, Bullifent HL, Moore K, Paszkiewicz K, Saint RJ, Southern SJ, Champion OL, Senior NJ, Sarkar-Tyson M, Oyston PCF, et al (2017). A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis. Sci Rep, 7 Abstract.  Author URL.
Flaviani F, Schroeder DC, Balestreri C, Schroeder JL, Moore K, Paszkiewicz K, Pfaff MC, Rybicki EP (2017). A Pelagic Microbiome (Viruses to Protists) from a Small Cup of Seawater. Viruses, 9(3). Abstract.  Author URL.
Senior NJ, Sasidharan K, Saint RJ, Scott AE, Sarkar-Tyson M, Ireland PM, Bullifent HL, Rong Yang Z, Moore K, Oyston PCF, et al (2017). An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions. BMC Microbiology, 17(1). Abstract.
Wiredu Boakye D, Jaroenlak P, Prachumwat A, Williams TA, Bateman K, Itsathiphaisarn O, Sritunyalucksan K, Paszkiewicz K, Moore KA, Stentiford G, et al (2017). Decay of the glycolytic pathway and adaptation to intranuclear parasitism within Enterocytozoonidae microsporidia. Environmental Microbiology, 19(5), 2077-2089.
Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2.
Dunthorn M, Zufall RA, Chi J, Paszkiewicz K, Moore K, Mahé F (2017). Meiotic Genes in Colpodean Ciliates Support Secretive Sexuality.
Dunthorn M, Zufall RA, Chi J, Paszkiewicz K, Moore K, Mahé F (2017). Meiotic Genes in Colpodean Ciliates Support Secretive Sexuality. Genome Biol Evol, 9(6), 1781-1787. Abstract.  Author URL.
Tennant RK, Sambles CM, Diffey GE, Moore KA, Love J (2017). Metagenomic Analysis of Silage. Journal of Visualized Experiments, 119, e54936-e54936.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga<i>Botryococcus braunii</i>. MicrobiologyOpen, 6(4), e00482-e00482.
Mitchelmore PJ, Randall J, Bull MJ, Moore KA, O'Neill PA, Paszkiewicz K, Mahenthiralingam E, Scotton CJ, Sheldon CD, Withers NJ, et al (2017). Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax Abstract.  Author URL.

2016

Williams TA, Nakjang S, Campbell SE, Freeman MA, Eydal M, Moore K, Hirt RP, Embley TM, Williams BAP (2016). A recent whole-genome duplication divides populations of a globally-distributed microsporidian. Molecular Biology and Evolution Abstract.
Gal C, Murton HE, Subramanian L, Whale AJ, Moore KM, Paszkiewicz K, Codlin S, Bähler J, Creamer KM, Partridge JF, et al (2016). Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation. EMBO Rep, 17(1), 79-93. Abstract.  Author URL.
Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.
Laver TW, Caswell RC, Moore KA, Poschmann J, Johnson MB, Owens MM, Ellard S, Paszkiewicz KH, Weedon MN (2016). Pitfalls of haplotype phasing from amplicon-based long-read sequencing. Sci Rep, 6 Abstract.  Author URL.
Shaw S, Le Cocq K, Paszkiewicz K, Moore K, Winsbury R, Studholme D, Salmon D, Thornton CR, Grant MR (2016). Transcriptional reprogramming underpins enhanced plant growth promotion by the biocontrol fungus Trichoderma hamatum GD12 during antagonistic interactions with Sclerotinia sclerotiorum in soil. Molecular Plant Pathology, 17, 1425-1441. Abstract.

2015

Price SJ, Garner TWJ, Balloux F, Ruis C, Paszkiewicz KH, Moore K, Griffiths AGF (2015). A de novo Assembly of the Common Frog (Rana temporaria) Transcriptome and Comparison of Transcription Following Exposure to Ranavirus and Batrachochytrium dendrobatidis. PLoS One, 10(6). Abstract.  Author URL.
Laver T, Harrison J, O'Neill PA, Moore K, Farbos A, Paszkiewicz K, Studholme DJ (2015). Assessing the performance of the Oxford Nanopore Technologies MinION. Biomolecular Detection and Quantification, 3, 1-8. Abstract.
Masood N, Moore K, Farbos A, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2015). Genomic dissection of the 1994 Cronobacter sakazakii outbreak in a French neonatal intensive care unit. BMC Genomics, 16 Abstract.  Author URL.
Uren Webster TM, Shears JA, Moore K, Santos EM (2015). Identification of conserved hepatic transcriptomic responses to 17β-estradiol using high-throughput sequencing in brown trout. Physiol Genomics, 47(9), 420-431. Abstract.  Author URL.
MacGregor DR, Kendall SL, Florance H, Fedi F, Moore K, Paszkiewicz K, Smirnoff N, Penfield S (2015). Seed production temperature regulation of primary dormancy occurs through control of seed coat phenylpropanoid metabolism. New Phytol, 205(2), 642-652. Abstract.  Author URL.
Gal C, Moore KM, Paszkiewicz K, Kent NA, Whitehall SK (2015). The impact of the HIRA histone chaperone upon global nucleosome architecture. Cell Cycle, 14(1), 123-134. Abstract.  Author URL.
Alkeskas A, Ogrodzki P, Saad M, Masood N, Rhoma NR, Moore K, Farbos A, Paszkiewicz K, Forsythe S (2015). The molecular characterisation of Escherichia coli K1 isolated from neonatal nasogastric feeding tubes. BMC Infect Dis, 15 Abstract.  Author URL.
Watson AK, Williams TA, Williams BAP, Moore KA, Hirt RP, Embley TM (2015). Transcriptomic profiling of host-parasite interactions in the microsporidian Trachipleistophora hominis. BMC Genomics Abstract.

2014

Harrison J, Moore K, Paszkiewicz K, Jones T, Grant M, Ambacheew D, Muzemil S, Studholme D (2014). A Draft Genome Sequence for Ensete ventricosum, the Drought-Tolerant “Tree Against Hunger”. Agronomy, 4, 13-33. Abstract.
Heintzman PD, Elias SA, Moore K, Paszkiewicz K, Barnes I (2014). Characterizing DNA preservation in degraded specimens of Amara alpina (Carabidae: Coleoptera). Mol Ecol Resour, 14(3), 606-615. Abstract.  Author URL.
Masood N, Jackson E, Moore K, Farbos A, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2014). Draft Genome Sequence of "Candidatus Cronobacter colletis" NCTC 14934T, a New Species in the Genus Cronobacter. Genome Announc, 2(3). Abstract.  Author URL.
Bertolini C, van Aerle R, Lampis S, Moore KA, Paszkiewicz K, Butler CS, Vallini G, van der Giezen M (2014). Draft Genome Sequence of Stenotrophomonas maltophilia SeITE02, a Gammaproteobacterium Isolated from Selenite-Contaminated Mining Soil. Genome Announc, 2(3). Abstract.  Author URL.
Chen M, MacGregor DR, Dave A, Florance H, Moore K, Paszkiewicz K, Smirnoff N, Graham IA, Penfield S (2014). Maternal temperature history activates Flowering Locus T in fruits to control progeny dormancy according to time of year. Proc Natl Acad Sci U S A, 111(52), 18787-18792. Abstract.  Author URL.
Paszkiewicz KH, Farbos A, O'Neill P, Moore K (2014). Quality control on the frontier. Front Genet, 5 Abstract.  Author URL.
Milne SW, Cheetham J, Lloyd D, Shaw S, Moore K, Paszkiewicz KH, Aves SJ, Bates S (2014). Role of Candida albicans Tem1 in mitotic exit and cytokinesis. Fungal Genet Biol, 69, 84-95. Abstract.  Author URL.

2013

Maruyama H, Harwood JC, Moore KM, Paszkiewicz K, Durley SC, Fukushima H, Atomi H, Takeyasu K, Kent NA (2013). An alternative beads-on-a-string chromatin architecture in Thermococcus kodakarensis. EMBO Rep, 14(8), 711-717. Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Block C, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft Genome Sequence of a Meningitic Isolate of Cronobacter sakazakii Clonal Complex 4, Strain 8399. Genome Announc, 1(5). Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft Genome Sequence of the Earliest Cronobacter sakazakii Sequence Type 4 Strain, NCIMB 8272. Genome Announc, 1(5). Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft Genome Sequences of Three Newly Identified Species in the Genus Cronobacter, C. helveticus LMG23732T, C. pulveris LMG24059, and C. zurichensis LMG23730T. Genome Announc, 1(5). Abstract.  Author URL.
Masood N, Moore K, Farbos A, Hariri S, Block C, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft genome sequence of a meningitic isolate of Cronobacter sakazakii clonal complex 4, strain 8399. Genome Announcements, 1(5). Abstract.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft genome sequence of the earliest Cronobacter sakazakii sequence type 4 strain, NCIMB 8272. Genome Announcements, 1(5). Abstract.
Masood N, Moore K, Farbos A, Hariri S, Paszkiewicz K, Dickins B, McNally A, Forsythe S (2013). Draft genome sequences of three newly identified species in the genus Cronobacter, C. helveticus LMG23732<sup>T</sup>, C. pulveris LMG24059, and C. zurichensis LMG23730<sup>T</sup>. Genome Announcements, 1(5). Abstract.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA -directed DNA methylation. Plant Journal, 75(5), 836-846. Abstract.
Brabbs TR, He Z, Hogg K, Kamenski A, Li Y, Paszkiewicz KH, Moore KA, O'Toole P, Graham IA, Jones L, et al (2013). The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA-directed DNA methylation. Plant Journal

2011

Taylor M, Moore K, Murray J, Aves SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10(11), 1154-1163.

2008

Moore, K. Aves, S.J. (2008). Mcm10 and DNA replication in fission yeast. In Bryant J, Francis D (Eds.) The Eukaryotic Cell Cycle, Taylor & Francis, 45-69.

2003

Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2003). The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002). NATURE, 421(6918), 94-94. Author URL.

2002

Hart EA, Bryant JA, Moore K, Aves SJ (2002). Fission yeast Cdc23 interactions with DNA replication initiation proteins. Curr Genet, 41(5), 342-348. Abstract.  Author URL.
Aves SJ, Gwilliam R, Wood V, Xiang Z (2002). The genome sequence of Schizosaccharomyces pombe. Nature, 415(6874), 871-880.

2001

Moore, K. Aves, S.J. (2001). Origins and complexes: the initiation of DNA replication. Journal of Experimental Botany, 52, 193-202.
Hunt C, Moore K, Xiang Z, Hurst SM, McDougall RC, Rajandream MA, Barrell BG, Gwilliam R, Wood V, Lyne MH, et al (2001). Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes. Yeast, 18(4), 355-361. Abstract.  Author URL.

2000

Xiang Z, Moore K, Wood V, Rajandream MA, Barrell BG, Skelton J, Churcher CM, Lyne MH, Devlin K, Gwilliam R, et al (2000). Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5. Yeast, 16(15), 1405-1411. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). Current awareness on yeast. Yeast, 16(11), 1069-1076. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). Identification of a Candida albicans homologue of the PHO85 gene, a negative regulator of the PHO system in Saccharomyces cerevisiae. Yeast, 16(11), 1045-1051. Abstract.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). The mating-type region of Schizosaccharomyces pombe h(-S) 972: Sequencing and analysis of 69 kb including the expressed matl locus. Yeast, 16(11), 1061-1067. Abstract.

1999

Munns MS, Moore K, Jossé L, Fitchett PN, Bryant JA (1999). The use of a multiple antigen peptide to detect a minichromosome maintenance protein in pea (Pisum sativum). In  (Ed) EBO Experimental Biology Online Annual 1998, 89-95.

1998

Munns MS, Moore K, Jossé L, Fitchett PN, Bryant JA (1998). The use of a multiple antigen peptide to detect a minichromosome maintenance protein in pea (Pisum sativum). Experimental Biology Online, 3(7), 1-5.

1997

Talbot NJ, McCafferty HRK, Ma M, Moore K, Hamer JE (1997). Nitrogen starvation of the rice blast fungus Magnaporthe grisea may act as an environmental cue for disease symptom expression. PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 50(3), 179-195. Author URL.

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Karen Moore

Teaching

PhD Students (PG researchers) and Postdoctoral researchers:

The Wellcome Trust awarded the University a £1.5million  Institutional Strategic Support Fund (ISSF) in 2012, which allowed me to join the Biomedical Informatics Hub as a molecular biology applications specialist whilst continuing to supervise the preparation and running of NGS projects for Exeter Sequencing Service. Therefore, a minimum of 10% of my time will always be available to support pilot projects and offer training courses to any technician, PhD students, PDRAs or academic within the University.

Laboratory Science Apprentice

I supervise and train a laboratory science apprentice (level 3) who works 4 days a week in the ESS laboratory and attends South Devon Collage for 1 day a week. I liaise with the collage tutors to ensure a coordinated training scheme.

PoreCamp

I was involved in 42 participants from 13 countries generated over 5Tb of sequencing data during the University of Exeter Porecamp held at Penryn Campus in Cornwall during 15-19 August 2016. Groups generated data for over 36 projects for sequencing on Oxford Nanopore’s MinION platform. These including WGS bacterial sequencing, PCR amplicons and BAC sequencing to help close mammalian genomes.

Supervision / Group

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