Dr Sariqa Wagley
Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK
Office hours: I work from Monday – Thursday 8am-4pm
I work from Monday – Thursday 8am-4pm
I am a microbiologist with a strong interest on researching the molecular basis of infection by bacterial pathogens. I completed a BSc in Medical Microbiology from the University of Surrey. During this degree programme I completed a year in industry at the Cefas laboratories in Weymouth working on the microbiological safety of shellfish. During this placement I worked on a pilot project to develop methods to detect pathogenic Vibrio species in shellfish such as V. cholerae, V. parahaemolyticus and V. vulnificus. My PhD studies were carried out at the Cefas laboratories (Weymouth, UK) in conjunction with the University of Surrey. Here, I worked on the human pathogen V. parahaemolyticus where I developed and standardised both molecular and classical approaches to the enumeration and characterisation of pathogenic V. parahaemolyticus in seafood’s, and to harmonise the use of those methods across the European Community.
After my PhD, I chose to move to a position with a strong molecular focus with Prof. Richard Titball at Exeter University. During my time at Exeter University I have focused my research and skillset on understanding microbial pathogenesis in a number of human pathogens including Burkholderia pseudomallei, Yersinia pseudotuberculosis, Campylobacter species and Clostridium perfringens. I am eager to combine the techniques from both my PhD and post-doctoral work to help further my own research on V. parahaemolyticus. I have recently been awarded a BBSRC IPA grant to help pursue my molecular interest in the viable but non-culturable state of V. parahaemolyticus and to study the role this phenomenon may have on food safety.
Associate Fellow of the Higher Education Academy (2014) University of Exeter
PhD (2008) Cefas laboratories Weymouth UK/University of Surrey, Development of methods for the detection and characterisation of pathogenic Vibrio parahaemolyticus in seafood
BSc Hons (2004) Medical Microbiology, University of Surrey
July 2021 - Lecturer, Education & Scholarship Fellow, MRC- Centre for Medical Mycology, Biosciences, Univeristy of Exeter.
July 2020 to July 2021 - Education & Scholarship Fellow, Project Enhance’ Manager, Biosciences, Univeristy of Exeter.
2008 - present - Research Fellow, Biosciences, Univeristy of Exeter
2004-2008 - Microbiologist PhD Student, Cefas, Weymouth, UK
2002 - 2003 - Microbiologist, Cefas, Weymouth,
Vibrio parahaemolyticus is a bacterium that is present in the marine environment and can be found in seawater, shellfish (such as oysters and mussels) and in crustacea (such as crab). This bacterium is the leading cause of seafood associated gastroenteritis worldwide. The bacterium can be destroyed during the cooking process, thus infection is generally associated with eating raw shellfish or cooked seafood products that have been cross-contaminated by raw shellfish or contaminated water. V. parahaemolyticus infections peak in the summer seasons, when sea temperatures are optimum for its growth. In the last 10 years the number of V. parahaemolyticus outbreaks has increased worldwide and has been as a result of rising sea temperatures. Climate change, globalisation and other drivers have also made Europe a hot spot for emerging infectious diseases including infections by V. parahaemolyticus.
At present, detection of V. parahaemolyticus is not required under EU Food Hygiene legislation for testing of shellfish harvesting areas and ready to eat seafood products. Furthermore, disease associated with V. parahaemolyticus is not notifiable in the EU but in recent years there have been a number of outbreaks associated with contaminated seafood in Europe including Spain, Italy and Norway that have begun to change the significance of this pathogen in Europe. I would like to develop my research to understand the molecular basis of infection of V. parahaemolyticus, how it survives in the environment, and to explore the epidemiological significance of this pathogen in UK environment.
- Understanding how the bacterium Vibrio parahaemolyticus causes disease
- The role of viable but non-culturable cells of V. parahaemolyticus and its significance on food safety
- Galleria mellonella as an alternative infection model for V. parahaemolyticus.
- Exploring the epidemiological significance of V. parahaemolyticus in the environment
- Understand the role of Clostridium perfringens epsilon toxin in Multiple sclerosis
- Studying carbon utilisation in Campylobacter species
- Understanding the role of a proteasome inhibitor (glbC) in Burkholderia pseudomallei
- Identification and characterisation of the Twin Arginie Translocation system in Burkholderia pseudomallei and Burkholderia thailandenisis
- 2020: University of Exeter: Researcher Led Initiatives Grant. Conduct a national workshop called ‘The ImageStream Revolution! A novel solution to answering complex environmental questions’. (Co-Applicant).
- 2019: Microbiology Travel Grant £750 to travel and present at International Vibrio Conference in Montreal, Canada.
- 2016-2020: BBSRC Industrial Partnership Award: ‘Uncovering the molecular basis of infection of viable but non-culturable cells’. (Researcher Co-Investigator).
- 2016-2020: Lyons Seafood (Warminster, UK): ‘Uncovering the molecular basis of infection of viable but non-culturable cells’. (Researcher Co-Investigator).
- 2014: GW4+ Innovation Primer Fund: ‘Using remote sensing modelling to monitor the incidence of the human pathogen V. parahaemolyticus in the UK.’ Dr Sariqa Wagley (Principal Investigator),
- 2012: Cefas Laboratories: Consumables grant to understand the molecular basis of disease in V. parahaemolyticus. (Principal Investigator). I
- 2012: University of Exeter: Researcher Led Initiatives Grant. Conduct a workshop for early career researchers entitled ‘Women in Science: A workshop for young researchers’. (Principal Investigator).
Publications by category
Publications by year
sariqa_wagley Details from cache as at 2022-10-06 21:31:02
- Teach on BIO2078 (Medical and General Biology)
- Supervision of final year undergraduate research projects