People

All Exeter Staff | All Cornwall Staff

Loading content
Dr Ben Longdon

Dr Ben Longdon

Sir Henry Dale Wellcome Trust and Royal Society Research Fellow

 01326259460

 Daphne du Maurier 3082

 

Daphne du Maurier Building, University of Exeter,  Penryn Campus, Penryn, Cornwall, TR10 9FE, UK

My research focuses on host-parasite ecology and evolution. Current work focuses on how parasites switch between host species, what factors affect the ability of parasites to successfully host shift and how these may be important for the emergence of novel pathogens. Other interests include the evolution and ecology of vertically transmitted parasites and how they spread through new host species or populations. I use insects and their natural viruses to examine these questions.

For more information visit the lab website: https://benlongdon.com.

Qualifications

2011 PhD, Institute of Evolutionary Biology, University of Edinburgh
2006 BSc Biology, University of Bristol

Career

2016- Sir Henry Dale Wellcome Trust and Royal Society Senior Research Fellow, University of Exeter
2012-2016 Postdoctoral Researcher, Department of Genetics, University of Cambridge

Links

Research

Research interests

Evolution and ecology of host-parasite Interactions

Research projects

Research in the lab focuses on several areas related to host-parasite evolution and ecology, using insects and their natural viral pathogens as a model system.

Current topics of research include:

  • The evolutionary and mechanistic basis of virus host shifts
  • Examining how genetic variation in host susceptibility differ between natural and non-natural parasites
  • Exploring the diversity of insect rhabdoviruses, how these viruses are transmitted and sweep through host populations

Grants/Funding:

  • Sir Henry Dale Fellowship from the Wellcome Trust and Royal Society: The evolutionary and mechanistic basis of virus host shifts (PI).
  • NERC grant: The causes of genetic variation in susceptibility to infectious disease in natural populations (Co-I with Frank Jiggins, University of Cambridge)

Key publications | Publications by category | Publications by year

Key publications


Longdon B, Day JP, Alves JM, Smith SCL, Houslay TM, McGonigle JE, Tagliaferri L, Jiggins FM (2018). Host shifts result in parallel genetic changes when viruses evolve in closely related species. PLoS Pathogens Full text.
Longdon B, Hadfield JD, Day JP, Smith SCL, McGonigle JE, Cogni R, Cao C, Jiggins FM (2015). The causes and consequences of changes in virulence following pathogen host shifts. PLoS Pathog, 11(3). Abstract.  Author URL.
Longdon B, Murray GGR, Palmer WJ, Day JP, Parker DJ, Welch JJ, Obbard DJ, Jiggins FM (2015). The evolution, diversity, and host associations of rhabdoviruses. Virus Evolution, 1(1).
Longdon B, Hadfield JD, Webster CL, Obbard DJ, Jiggins FM (2011). Host phylogeny determines viral persistence and replication in novel hosts. PLoS Pathog, 7(9). Abstract.  Author URL.
Longdon B, Wilfert L, Obbard DJ, Jiggins FM (2011). Rhabdoviruses in two species of Drosophila: vertical transmission and a recent sweep. Genetics, 188(1), 141-150. Abstract.  Author URL.

Publications by category


Journal articles

Longdon B, Day JP, Alves JM, Smith SCL, Houslay TM, McGonigle JE, Tagliaferri L, Jiggins FM (2018). Host shifts result in parallel genetic changes when viruses evolve in closely related species. PLoS Pathogens Full text.
Walker PJ, Blasdell KR, Calisher CH, Dietzgen RG, Kondo H, Kurath G, Longdon B, Stone DM, Tesh RB, Tordo N, et al (2018). ICTV Virus Taxonomy Profile: Rhabdoviridae. J Gen Virol, 99(4), 447-448. Abstract.  Author URL.  Full text.
Antonovics J, Wilson AJ, Forbes MR, Hauffe HC, Kallio ER, Leggett HC, Longdon B, Okamura B, Sait SM, Webster JP, et al (2017). The evolution of transmission mode. Philos Trans R Soc Lond B Biol Sci, 372(1719). Abstract.  Author URL.  Full text.
Longdon B, Day JP, Schulz N, Leftwich PT, De Jong MA, Breuker CJ, Gibbs M, Obbard DJ, Wilfert L, Smith SCL, et al (2017). Vertically transmitted rhabdoviruses are found across three insect families and have dynamic interactions with their hosts. Proceedings of the Royal Society B: Biological Sciences, 284(1847). Abstract.  Full text.
Webster CL, Longdon B, Lewis SH, Obbard DJ (2016). Twenty-five new viruses associated with the drosophilidae (Diptera). Evolutionary Bioinformatics, 12, 13-25. Abstract.  Full text.
Vrancken B, Lemey P, Rambaut A, Bedford T, Longdon B, G√ľnthard HF, Suchard MA (2015). Simultaneously estimating evolutionary history and repeated traits phylogenetic signal: applications to viral and host phenotypic evolution. Methods Ecol Evol, 6(1), 67-82. Abstract.  Author URL.
Webster CL, Waldron FM, Robertson S, Crowson D, Ferrari G, Quintana JF, Brouqui J-M, Bayne EH, Longdon B, Buck AH, et al (2015). The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster. PLoS Biol, 13(7). Abstract.  Author URL.
Longdon B, Hadfield JD, Day JP, Smith SCL, McGonigle JE, Cogni R, Cao C, Jiggins FM (2015). The causes and consequences of changes in virulence following pathogen host shifts. PLoS Pathog, 11(3). Abstract.  Author URL.
Longdon B, Murray GGR, Palmer WJ, Day JP, Parker DJ, Welch JJ, Obbard DJ, Jiggins FM (2015). The evolution, diversity, and host associations of rhabdoviruses. Virus Evolution, 1(1).
Martinez J, Longdon B, Bauer S, Chan Y-S, Miller WJ, Bourtzis K, Teixeira L, Jiggins FM (2014). Symbionts commonly provide broad spectrum resistance to viruses in insects: a comparative analysis of Wolbachia strains. PLoS Pathog, 10(9). Abstract.  Author URL.
Longdon B, Brockhurst MA, Russell CA, Welch JJ, Jiggins FM (2014). The evolution and genetics of virus host shifts. PLoS Pathog, 10(11). Abstract.  Author URL.
Longdon B, Cao C, Martinez J, Jiggins FM (2013). Previous exposure to an RNA virus does not protect against subsequent infection in Drosophila melanogaster. PLoS One, 8(9). Abstract.  Author URL.
Magwire MM, Fabian DK, Schweyen H, Cao C, Longdon B, Bayer F, Jiggins FM (2012). Genome-Wide Association Studies Reveal a Simple Genetic Basis of Resistance to Naturally Coevolving Viruses in Drosophila melanogaster. PLoS Genetics, 8(11), e1003057-e1003057.
Longdon B, Fabian DK, Hurst GDD, Jiggins FM (2012). Male-killing Wolbachia do not protect Drosophila bifasciata against viral infection. BMC Microbiol, 12 Suppl 1 Abstract.  Author URL.
Longdon B, Jiggins FM (2012). Vertically transmitted viral endosymbionts of insects: do sigma viruses walk alone?. Proc Biol Sci, 279(1744), 3889-3898. Abstract.  Author URL.
Longdon B, Hadfield JD, Webster CL, Obbard DJ, Jiggins FM (2011). Host phylogeny determines viral persistence and replication in novel hosts. PLoS Pathog, 7(9). Abstract.  Author URL.
Longdon B, Wilfert L, Osei-Poku J, Cagney H, Obbard DJ, Jiggins FM (2011). Host-switching by a vertically transmitted rhabdovirus in Drosophila. Biol Lett, 7(5), 747-750. Abstract.  Author URL.
Longdon B, Wilfert L, Obbard DJ, Jiggins FM (2011). Rhabdoviruses in two species of Drosophila: vertical transmission and a recent sweep. Genetics, 188(1), 141-150. Abstract.  Author URL.
Wilfert L, Longdon B, Ferreira AGA, Bayer F, Jiggins FM (2011). Trypanosomatids are common and diverse parasites of Drosophila. Parasitology, 138(7), 858-865. Abstract.  Author URL.
Longdon B, Jiggins FM (2010). Quick guide. Paternally transmitted parasites. Curr Biol, 20(17), R695-R696. Author URL.
Longdon B, Obbard DJ, Jiggins FM (2010). Sigma viruses from three species of Drosophila form a major new clade in the rhabdovirus phylogeny. Proc Biol Sci, 277(1678), 35-44. Abstract.  Author URL.
Aleksiev AS, Longdon B, Christmas MJ, Sendova-Franks AB, Franks NR (2008). Individual and collective choice: parallel prospecting and mining in ants. Naturwissenschaften, 95(4), 301-305. Abstract.  Author URL.
Aleksiev AS, Longdon B, Christmas MJ, Sendova-Franks AB, Franks NR (2007). Individual choice of building material for nest construction by worker ants and the collective outcome for their colony. Animal Behaviour, 74(3), 559-566. Abstract.

Publications by year


2018

Longdon B, Day JP, Alves JM, Smith SCL, Houslay TM, McGonigle JE, Tagliaferri L, Jiggins FM (2018). Host shifts result in parallel genetic changes when viruses evolve in closely related species. PLoS Pathogens Full text.
Walker PJ, Blasdell KR, Calisher CH, Dietzgen RG, Kondo H, Kurath G, Longdon B, Stone DM, Tesh RB, Tordo N, et al (2018). ICTV Virus Taxonomy Profile: Rhabdoviridae. J Gen Virol, 99(4), 447-448. Abstract.  Author URL.  Full text.

2017

Antonovics J, Wilson AJ, Forbes MR, Hauffe HC, Kallio ER, Leggett HC, Longdon B, Okamura B, Sait SM, Webster JP, et al (2017). The evolution of transmission mode. Philos Trans R Soc Lond B Biol Sci, 372(1719). Abstract.  Author URL.  Full text.
Longdon B, Day JP, Schulz N, Leftwich PT, De Jong MA, Breuker CJ, Gibbs M, Obbard DJ, Wilfert L, Smith SCL, et al (2017). Vertically transmitted rhabdoviruses are found across three insect families and have dynamic interactions with their hosts. Proceedings of the Royal Society B: Biological Sciences, 284(1847). Abstract.  Full text.

2016

Webster CL, Longdon B, Lewis SH, Obbard DJ (2016). Twenty-five new viruses associated with the drosophilidae (Diptera). Evolutionary Bioinformatics, 12, 13-25. Abstract.  Full text.

2015

Vrancken B, Lemey P, Rambaut A, Bedford T, Longdon B, G√ľnthard HF, Suchard MA (2015). Simultaneously estimating evolutionary history and repeated traits phylogenetic signal: applications to viral and host phenotypic evolution. Methods Ecol Evol, 6(1), 67-82. Abstract.  Author URL.
Webster CL, Waldron FM, Robertson S, Crowson D, Ferrari G, Quintana JF, Brouqui J-M, Bayne EH, Longdon B, Buck AH, et al (2015). The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster. PLoS Biol, 13(7). Abstract.  Author URL.
Longdon B, Hadfield JD, Day JP, Smith SCL, McGonigle JE, Cogni R, Cao C, Jiggins FM (2015). The causes and consequences of changes in virulence following pathogen host shifts. PLoS Pathog, 11(3). Abstract.  Author URL.
Longdon B, Murray GGR, Palmer WJ, Day JP, Parker DJ, Welch JJ, Obbard DJ, Jiggins FM (2015). The evolution, diversity, and host associations of rhabdoviruses. Virus Evolution, 1(1).

2014

Martinez J, Longdon B, Bauer S, Chan Y-S, Miller WJ, Bourtzis K, Teixeira L, Jiggins FM (2014). Symbionts commonly provide broad spectrum resistance to viruses in insects: a comparative analysis of Wolbachia strains. PLoS Pathog, 10(9). Abstract.  Author URL.
Longdon B, Brockhurst MA, Russell CA, Welch JJ, Jiggins FM (2014). The evolution and genetics of virus host shifts. PLoS Pathog, 10(11). Abstract.  Author URL.

2013

Longdon B, Cao C, Martinez J, Jiggins FM (2013). Previous exposure to an RNA virus does not protect against subsequent infection in Drosophila melanogaster. PLoS One, 8(9). Abstract.  Author URL.

2012

Magwire MM, Fabian DK, Schweyen H, Cao C, Longdon B, Bayer F, Jiggins FM (2012). Genome-Wide Association Studies Reveal a Simple Genetic Basis of Resistance to Naturally Coevolving Viruses in Drosophila melanogaster. PLoS Genetics, 8(11), e1003057-e1003057.
Longdon B, Fabian DK, Hurst GDD, Jiggins FM (2012). Male-killing Wolbachia do not protect Drosophila bifasciata against viral infection. BMC Microbiol, 12 Suppl 1 Abstract.  Author URL.
Longdon B, Jiggins FM (2012). Vertically transmitted viral endosymbionts of insects: do sigma viruses walk alone?. Proc Biol Sci, 279(1744), 3889-3898. Abstract.  Author URL.

2011

Longdon B, Hadfield JD, Webster CL, Obbard DJ, Jiggins FM (2011). Host phylogeny determines viral persistence and replication in novel hosts. PLoS Pathog, 7(9). Abstract.  Author URL.
Longdon B, Wilfert L, Osei-Poku J, Cagney H, Obbard DJ, Jiggins FM (2011). Host-switching by a vertically transmitted rhabdovirus in Drosophila. Biol Lett, 7(5), 747-750. Abstract.  Author URL.
Longdon B, Wilfert L, Obbard DJ, Jiggins FM (2011). Rhabdoviruses in two species of Drosophila: vertical transmission and a recent sweep. Genetics, 188(1), 141-150. Abstract.  Author URL.
Wilfert L, Longdon B, Ferreira AGA, Bayer F, Jiggins FM (2011). Trypanosomatids are common and diverse parasites of Drosophila. Parasitology, 138(7), 858-865. Abstract.  Author URL.

2010

Longdon B, Jiggins FM (2010). Quick guide. Paternally transmitted parasites. Curr Biol, 20(17), R695-R696. Author URL.
Longdon B, Obbard DJ, Jiggins FM (2010). Sigma viruses from three species of Drosophila form a major new clade in the rhabdovirus phylogeny. Proc Biol Sci, 277(1678), 35-44. Abstract.  Author URL.

2008

Aleksiev AS, Longdon B, Christmas MJ, Sendova-Franks AB, Franks NR (2008). Individual and collective choice: parallel prospecting and mining in ants. Naturwissenschaften, 95(4), 301-305. Abstract.  Author URL.

2007

Aleksiev AS, Longdon B, Christmas MJ, Sendova-Franks AB, Franks NR (2007). Individual choice of building material for nest construction by worker ants and the collective outcome for their colony. Animal Behaviour, 74(3), 559-566. Abstract.

Ben_Longdon Details from cache as at 2018-04-20 02:04:55

Refresh publications

Media Coverage

My research has been featured on:

Virulence following host shifts
Microbiology Society BlogScience Daily

Phylogenetic determinants of host shifts
BBC TV, BBC Radio Scotland (live interview), BBC online, The Metro, The ScotsmanScience Daily, The Press Association, The Herald, Press and Journal, Edinburgh Evening News, BBSRC website, MSN news, Yahoo News, The West Australian, Rule of 6ix via Nature.com blogs and National Public Radio (USA)


Significant Impact

With collaborators at FoAM Kernow we are developing a Wellcome Trust funded citizen science project (“Viruscraft“) using visual programming, craft, tangible interfaces and games to explore virus host shifts – where a virus jumps from one host species to another.

Postdoctoral researchers

Postgraduate researchers

Back | Edit Profile