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Dr Patrick Hamilton

Lecturer (E&S)

 3438

 Geoffrey Pope 320

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

I studied Natural Sciences at the University of Cambridge, specialising in Genetics in my final year.  I then studied for a PhD at the University of Bristol on a research project that applied DNA sequencing and phylogenetic analysis to explore the diversity and evolution of trypanosomes- protozoan blood parasites that cause serious diseases of livestock and humans in South America and Africa. 

I came to Exeter University in 2005 to work on a range of projects that have aimed to better understand the impacts of pollution of fish populations.   These projects have employed a combination of long-term experiments and molecular methods – particularly DNA microsatellite and SNP genotyping.  My most recent research project has investigated whether freshwater fish populations exposed to sewage effluents over many generations have genetically adapted to become less responsive to the harmful effects of estrogen pollution.

In 2016 I left Exeter to do a PGCE in Secondary Science and then teach at a secondary school. I recently returned to Exeter University as a lecturer (Education and Scholarship).

I also have roles as:

I teach on a range of first and second year courses including Biochemistry, Genetics, Microbiology and Forensic Science.   I am module coordinator for Forensic Science.

Qualifications

2016 - PGCE- University of Exeter

2007 - Associate Fellow of the Higher Education Academy

2003 - PhD - Molecular Ecology - University of Bristol

1998 - BA(Hons) – Natural Sciences (Genetics) - University of Cambridge

Research

Research interests

I am a member of the Molecular Ecology & Evolution Group (MEEG).  I have several major research interests resulting from the research projects I have been involved in. Most of my work has applied genetic methods to address questions within these topics.

My major recent research interest has been understanding the impacts of chemical pollution on fish populations.  In collaboration with Brunel University we have undertaken two large-scale studies that aimed to better understand the impact of estrogen pollution on fish populations.   Long term exposure to estrogen pollution feminises male fish.  Through this work we have demonstrated that wild male roach with feminsed gonads have a reduced capacity to breed when completing with normal males.   Our most recent project has used a combination of long-term experiments and SNP genotyping to investigate whether roach have the capacity to adapt to estrogen pollution.

Another major research interest is in the diversity and evolution of trypanosomes.  These are protozoan parasites that cause a range of diseases in humans and domestic livestock.   Some of the highlights from this work include providing strong evidence for a single origin of trypanosomes and the proposal of the now widely accepted hypothesis that the human pathogen, Trypanosoma cruzi evolved from a parasite that infects bats.   Our work has also led to a much better understanding of the diversity of trypanosomes that infect wildlife and domestic livestock in Africa. 

I also have an interest in the application of genetic methods to better conserve populations of Bechstein’s bat, a rare woodland species in the UK.   We have investigated population genetic structure across Europe.  Recently we published a paper demonstrating the potential to genetically age bats by measuring DNA methylation on several key genes.

In 2006 I published a book on Plant Conservation.  I continue to have an interest in effective plant conservation strategies. 

 

 

Research projects

  • Can roach adapt to harmful effects of estrogen pollution in UK rivers?

  • Europe-wide phylogeography of roach (Rutilus rutilus) using mitochondrial and microsatellite genotyping.

  • The development and application of molecular tools to better understand population genetic structure and to aid conservation of Bechstein’s bat.

     

Key publications | Publications by category | Publications by year

Key publications


Hamilton PB, Nicol E, De-Bastos ESR, Williams RJ, Sumpter JP, Jobling S, Stevens JR, Tyler CR (2014). Populations of a cyprinid fish are self-sustaining despite widespread feminization of males. BMC Biol, 12 Abstract.  Author URL.  Full text.
Hamilton PB, Teixeira MMG, Stevens JR (2012). The evolution of Trypanosoma cruzi: the 'bat seeding' hypothesis. Trends in Parasitology, 28(4), 136-141. Abstract.
Lange A, Paull GC, Hamilton PB, Iguchi T, Tyler CR (2011). Implications of persistent exposure to treated wastewater effluent for breeding in wild roach (Rutilus rutilus) populations. Environ Sci Technol, 45(4), 1673-1679. Abstract.  Author URL.
Harris CA, Hamilton PB, Runnalls TJ, Vinciotti V, Henshaw A, Hodgson D, Coe TS, Jobling S, Tyler CR, Sumpter JP, et al (2011). The consequences of feminization in breeding groups of wild fish. Environ Health Perspect, 119(3), 306-311. Abstract.  Author URL.  Full text.
Coe TS, Hamilton PB, Hodgson D, Paull GC, Stevens JR, Sumner K, Tyler CR (2008). An environmental estrogen alters reproductive hierarchies, disrupting sexual selection in group-spawning fish. Environ Sci Technol, 42(13), 5020-5025. Abstract.  Author URL.
Hamilton PB, Gibson WC, Stevens JR (2007). Patterns of co-evolution between trypanosomes and their hosts deduced from ribosomal RNA and protein-coding gene phylogenies. Mol Phylogenet Evol, 44(1), 15-25. Abstract.  Author URL.

Publications by category


Books

Hamilton AC, Hamilton PB (eds)(2006). Plant Conservation - an Ecological Approach. London, Earthscan Press. Abstract.

Journal articles

Hamilton PB, Rolshausen G, Uren Webster TM, Tyler CR (In Press). Adaptive capabilities and fitness consequences associated with pollution exposure in fish. Philos Trans R Soc Lond B Biol Sci, 372(1712). Abstract.  Author URL.
Lima L, Espinosa-Álvarez O, Pinto CM, Cavazzana M, Pavan AC, Carranza JC, Lim BK, Campaner M, Takata CSA, Camargo EP, et al (2015). New insights into the evolution of the Trypanosoma cruzi clade provided by a new trypanosome species tightly linked to Neotropical Pteronotus bats and related to an Australian lineage of trypanosomes. Parasit Vectors, 8 Abstract.  Author URL.
Hamilton PB, Nicol E, De-Bastos ESR, Williams RJ, Sumpter JP, Jobling S, Stevens JR, Tyler CR (2014). Populations of a cyprinid fish are self-sustaining despite widespread feminization of males. BMC Biol, 12 Abstract.  Author URL.  Full text.
Bickley LK, Brown AR, Hosken DJ, Hamilton PB, Le Page G, Paull GC, Owen SF, Tyler CR (2013). Interactive effects of inbreeding and endocrine disruption on reproduction in a model laboratory fish. Evolutionary Applications, 6(2), 279-289. Abstract.  Full text.
Santos EM, Hamilton PB, Coe TS, Ball JS, Cook AC, Katsiadaki I, Tyler CR (2013). Population bottlenecks, genetic diversity and breeding ability of the three-spined stickleback (Gasterosteus aculeatus) from three polluted English Rivers. Aquatic Toxicology, 142-143, 264-271. Abstract.
Fermino BR, Viola LB, Paiva F, Garcia HA, De Paula CD, Botero-Arias R, Takata CSA, Campaner M, Hamilton PB, Camargo EP, et al (2013). The phylogeography of trypanosomes from South American alligatorids and African crocodilids is consistent with the geological history of South American river basins and the transoceanic dispersal of Crocodylus at the Miocene. Parasites and Vectors, 6(1). Abstract.
Lima L, Espinosa-Álvarez O, Hamilton PB, Neves L, Takata CS, Campaner M, Attias M, De Souza W, Camargo EP, Teixeira MM, et al (2013). Trypanosoma livingstonei: a new species from African bats supports the bat seeding hypothesis for the Trypanosoma cruzi clade. Parasites and Vectors, 6(1). Abstract.
Brown AR, Bickley LK, Ryan TA, Paull GC, Hamilton PB, Owen SF, Sharpe AD, Tyler CR (2012). Differences in sexual development in inbred and outbred zebrafish (Danio rerio) and implications for chemical testing. Aquat Toxicol, 112-113, 27-38. Abstract.  Author URL.
Lima L, Silva FMD, Neves L, Attias M, Takata CSA, Campaner M, de Souza W, Hamilton PB, Teixeira MMG (2012). Evolutionary Insights from Bat Trypanosomes: Morphological, Developmental and Phylogenetic Evidence of a New Species, Trypanosoma (Schizotrypanum) erneyi sp. nov. in African Bats Closely Related to Trypanosoma (Schizotrypanum) cruzi and Allied Species. Protist
Lima L, Silva FMD, Neves L, Attias M, Takata CSA, Campaner M, de Souza W, Hamilton PB, Teixeira MMG (2012). Evolutionary Insights from Bat Trypanosomes: Morphological, Developmental and Phylogenetic Evidence of a New Species, Trypanosoma (Schizotrypanum) erneyi sp. nov. in African Bats Closely Related to Trypanosoma (Schizotrypanum) cruzi and Allied Species. Protist, 163(6), 856-872. Abstract.
Hamilton PB (2012). Is Trypanosoma vivax genetically diverse?. Trends Parasitol, 28(5). Author URL.
Hamilton PB (2012). Is Trypanosoma vivax genetically diverse?. Trends in Parasitology, 28(5).
Hamilton PB, Cruickshank C, Stevens JR, Teixeira MMG, Mathews F (2012). Parasites reveal movement of bats between the New and Old Worlds. Mol Phylogenet Evol, 63(2), 521-526. Abstract.  Author URL.
Hamilton PB, Teixeira MMG, Stevens JR (2012). The evolution of Trypanosoma cruzi: the 'bat seeding' hypothesis. Trends in Parasitology, 28(4), 136-141. Abstract.
Croft DP, Hamilton PB, Darden SK, Jacoby DMP, James R, Bettaney EM, Tyler CR (2012). The role of relatedness in structuring the social network of a wild guppy population. Oecologia, 1-9.
Croft DP, Hamilton PB, Darden SK, Jacoby DMP, James R, Bettaney EM, Tyler CR (2012). The role of relatedness in structuring the social network of a wild guppy population. Oecologia, 170(4), 955-963. Abstract.
Brown AR, Bickley LK, Le Page G, Hosken DJ, Paull GC, Hamilton PB, Owen SF, Robinson J, Sharpe AD, Tyler CR, et al (2011). Are toxicological responses in laboratory (inbred) zebrafish representative of those in outbred (wild) populations? - a case study with an endocrine disrupting chemical. Environ Sci Technol, 45(9), 4166-4172. Abstract.  Author URL.
Hamilton PB, Lewis MD, Cruickshank C, Gaunt MW, Yeo M, Llewellyn MS, Valente SA, Maia da Silva F, Stevens JR, Miles MA, et al (2011). Identification and lineage genotyping of South American trypanosomes using fluorescent fragment length barcoding. Infect Genet Evol, 11(1), 44-51. Abstract.  Author URL.
Lange A, Paull GC, Hamilton PB, Iguchi T, Tyler CR (2011). Implications of persistent exposure to treated wastewater effluent for breeding in wild roach (Rutilus rutilus) populations. Environ Sci Technol, 45(4), 1673-1679. Abstract.  Author URL.
Garcia HA, Rodrigues AC, Martinkovic F, Minervino AHH, Campaner M, Nunes VLB, Paiva F, Hamilton PB, Teixeira MMG (2011). Multilocus phylogeographical analysis of Trypanosoma (Megatrypanum) genotypes from sympatric cattle and water buffalo populations supports evolutionary host constraint and close phylogenetic relationships with genotypes found in other ruminants. International Journal for Parasitology, 41(13-14), 1385-1396. Abstract.
Hamilton PB, Stevens JR (2011). Resolving relationships between Australian trypanosomes using DNA barcoding data. Trends Parasitol, 27(3). Author URL.
Harris CA, Hamilton PB, Runnalls TJ, Vinciotti V, Henshaw A, Hodgson D, Coe TS, Jobling S, Tyler CR, Sumpter JP, et al (2011). The consequences of feminization in breeding groups of wild fish. Environ Health Perspect, 119(3), 306-311. Abstract.  Author URL.  Full text.
Adams ER, Hamilton PB, Gibson WC (2010). African trypanosomes: Celebrating diversity. Trends in Parasitology, 26(7), 324-328. Abstract.
Paull GC, Filby AL, Giddins HG, Coe TS, Hamilton PB, Tyler CR (2010). Dominance hierarchies in zebrafish (Danio rerio) and their relationship with reproductive success. Zebrafish, 7(1), 109-117. Abstract.  Author URL.
Adams ER, Hamilton PB, Rodrigues AC, Malele II, Delespaux V, Teixeira MMG, Gibson W (2010). New Trypanosoma (Duttonella) vivax genotypes from tsetse flies in East Africa. Parasitology, 137(4), 641-650. Abstract.
Coe TS, Hamilton PB, Griffiths AM, Hodgson DJ, Wahab MA, Tyler CR (2009). Genetic variation in strains of zebrafish (Danio rerio) and the implications for ecotoxicology studies. Ecotoxicology, 18(1), 144-150. Abstract.  Author URL.
Coe TS, Hamilton PB, Hodgson D, Paull GC, Tyler CR (2009). Parentage outcomes in response to estrogen exposure are modified by social grouping in zebrafish. Environ Sci Technol, 43(21), 8400-8405. Abstract.  Author URL.
Hamilton PB, Adams ER, Njiokou F, Gibson WC, Cuny G, Herder S (2009). Phylogenetic analysis reveals the presence of the Trypanosoma cruzi clade in African terrestrial mammals. Infect Genet Evol, 9(1), 81-86. Abstract.  Author URL.
Hamilton PB, Adams ER, Malele II, Gibson WC (2008). A novel, high-throughput technique for species identification reveals a new species of tsetse-transmitted trypanosome related to the Trypanosoma brucei subgenus, Trypanozoon. Infect Genet Evol, 8(1), 26-33. Abstract.  Author URL.
Coe TS, Hamilton PB, Hodgson D, Paull GC, Stevens JR, Sumner K, Tyler CR (2008). An environmental estrogen alters reproductive hierarchies, disrupting sexual selection in group-spawning fish. Environ Sci Technol, 42(13), 5020-5025. Abstract.  Author URL.
Adams ER, Hamilton PB (2008). New molecular tools for the indentification of trypanosome species. Future Microbiology, 3(2), 167-176. Abstract.
Tyler, C.R. (2007). Identification of microsatellite loci for parentage analysis in roach Rutilus rutilus and 8 other cyprinids by cross-species amplification, and a novel test for detecting hybrids between roach and other cyprinids. Molecular Ecology Notes
Hamilton PB, Gibson WC, Stevens JR (2007). Patterns of co-evolution between trypanosomes and their hosts deduced from ribosomal RNA and protein-coding gene phylogenies. Mol Phylogenet Evol, 44(1), 15-25. Abstract.  Author URL.
Hamilton P, Stevens, J.R. Gidley, P. Holz, P. Gibson W (2005). A new lineage of trypanosomes from Australian vertebrates and terrestrial bloodsucking leeches (Haemadipsidae). International Journal for Parasitology, 35, 431-443.
Hamilton P, Stevens, J.R. Holz, P. Boag, B. Gibson W (2005). The accidental introduction of the trypanosome of the introduced European rabbit (Oryctolagus cuniculus) to Australia and its potential for biocontrol. Molecular Ecology, 35, 431-443.
Hamilton PB, Stevens JR, Holz P, Boag B, Cooke B, Gibson WC (2005). The inadvertent introduction into Australia of Trypanosoma nabiasi, the trypanosome of the European rabbit (Oryctolagus cuniculus), and its potential for biocontrol. Mol Ecol, 14(10), 3167-3175. Abstract.  Author URL.
Hamilton P, Stevens, J.R. Gaunt, M.W. Gidley, J. Gibson W (2004). Trypanosomes are monophyletic: evidence from genes for glyceraldehyde phosphate dehydrogenase and small subunit ribosomal RNA. International Journal for Parasitology, 34, 1393-1404.

Chapters

Hamilton PB, Stevens, J.R. (2010). Classification and Phylogeny of Trypanosoma cruzi. In Tibayrenc M, Tellería J (Eds.) American Trypanosomiasis, an Elsevier Title.

Conferences

Tyler CR, Hamilton PB, Lange A, Filby AL, Soffkar M, Lee O, Takesono A, Kudoh T, Paull GC, Iguchi T, et al (2012). Health impacts of exposure to environmental oestrogens in fish.  Author URL.
Adams ER, Hamilton PB, Malele II, Gibson WC (2008). The identification, diversity and prevalence of trypanosomes in field caught tsetse in Tanzania using ITS-1 primers and fluorescent fragment length barcoding.  Abstract.

Publications by year


In Press

Hamilton PB, Rolshausen G, Uren Webster TM, Tyler CR (In Press). Adaptive capabilities and fitness consequences associated with pollution exposure in fish. Philos Trans R Soc Lond B Biol Sci, 372(1712). Abstract.  Author URL.

2015

Lima L, Espinosa-Álvarez O, Pinto CM, Cavazzana M, Pavan AC, Carranza JC, Lim BK, Campaner M, Takata CSA, Camargo EP, et al (2015). New insights into the evolution of the Trypanosoma cruzi clade provided by a new trypanosome species tightly linked to Neotropical Pteronotus bats and related to an Australian lineage of trypanosomes. Parasit Vectors, 8 Abstract.  Author URL.

2014

Hamilton PB, Nicol E, De-Bastos ESR, Williams RJ, Sumpter JP, Jobling S, Stevens JR, Tyler CR (2014). Populations of a cyprinid fish are self-sustaining despite widespread feminization of males. BMC Biol, 12 Abstract.  Author URL.  Full text.

2013

Bickley LK, Brown AR, Hosken DJ, Hamilton PB, Le Page G, Paull GC, Owen SF, Tyler CR (2013). Interactive effects of inbreeding and endocrine disruption on reproduction in a model laboratory fish. Evolutionary Applications, 6(2), 279-289. Abstract.  Full text.
Santos EM, Hamilton PB, Coe TS, Ball JS, Cook AC, Katsiadaki I, Tyler CR (2013). Population bottlenecks, genetic diversity and breeding ability of the three-spined stickleback (Gasterosteus aculeatus) from three polluted English Rivers. Aquatic Toxicology, 142-143, 264-271. Abstract.
Fermino BR, Viola LB, Paiva F, Garcia HA, De Paula CD, Botero-Arias R, Takata CSA, Campaner M, Hamilton PB, Camargo EP, et al (2013). The phylogeography of trypanosomes from South American alligatorids and African crocodilids is consistent with the geological history of South American river basins and the transoceanic dispersal of Crocodylus at the Miocene. Parasites and Vectors, 6(1). Abstract.
Lima L, Espinosa-Álvarez O, Hamilton PB, Neves L, Takata CS, Campaner M, Attias M, De Souza W, Camargo EP, Teixeira MM, et al (2013). Trypanosoma livingstonei: a new species from African bats supports the bat seeding hypothesis for the Trypanosoma cruzi clade. Parasites and Vectors, 6(1). Abstract.

2012

Brown AR, Bickley LK, Ryan TA, Paull GC, Hamilton PB, Owen SF, Sharpe AD, Tyler CR (2012). Differences in sexual development in inbred and outbred zebrafish (Danio rerio) and implications for chemical testing. Aquat Toxicol, 112-113, 27-38. Abstract.  Author URL.
Lima L, Silva FMD, Neves L, Attias M, Takata CSA, Campaner M, de Souza W, Hamilton PB, Teixeira MMG (2012). Evolutionary Insights from Bat Trypanosomes: Morphological, Developmental and Phylogenetic Evidence of a New Species, Trypanosoma (Schizotrypanum) erneyi sp. nov. in African Bats Closely Related to Trypanosoma (Schizotrypanum) cruzi and Allied Species. Protist
Lima L, Silva FMD, Neves L, Attias M, Takata CSA, Campaner M, de Souza W, Hamilton PB, Teixeira MMG (2012). Evolutionary Insights from Bat Trypanosomes: Morphological, Developmental and Phylogenetic Evidence of a New Species, Trypanosoma (Schizotrypanum) erneyi sp. nov. in African Bats Closely Related to Trypanosoma (Schizotrypanum) cruzi and Allied Species. Protist, 163(6), 856-872. Abstract.
Tyler CR, Hamilton PB, Lange A, Filby AL, Soffkar M, Lee O, Takesono A, Kudoh T, Paull GC, Iguchi T, et al (2012). Health impacts of exposure to environmental oestrogens in fish.  Author URL.
Hamilton PB (2012). Is Trypanosoma vivax genetically diverse?. Trends Parasitol, 28(5). Author URL.
Hamilton PB (2012). Is Trypanosoma vivax genetically diverse?. Trends in Parasitology, 28(5).
Hamilton PB, Cruickshank C, Stevens JR, Teixeira MMG, Mathews F (2012). Parasites reveal movement of bats between the New and Old Worlds. Mol Phylogenet Evol, 63(2), 521-526. Abstract.  Author URL.
Hamilton PB, Teixeira MMG, Stevens JR (2012). The evolution of Trypanosoma cruzi: the 'bat seeding' hypothesis. Trends in Parasitology, 28(4), 136-141. Abstract.
Croft DP, Hamilton PB, Darden SK, Jacoby DMP, James R, Bettaney EM, Tyler CR (2012). The role of relatedness in structuring the social network of a wild guppy population. Oecologia, 1-9.
Croft DP, Hamilton PB, Darden SK, Jacoby DMP, James R, Bettaney EM, Tyler CR (2012). The role of relatedness in structuring the social network of a wild guppy population. Oecologia, 170(4), 955-963. Abstract.

2011

Brown AR, Bickley LK, Le Page G, Hosken DJ, Paull GC, Hamilton PB, Owen SF, Robinson J, Sharpe AD, Tyler CR, et al (2011). Are toxicological responses in laboratory (inbred) zebrafish representative of those in outbred (wild) populations? - a case study with an endocrine disrupting chemical. Environ Sci Technol, 45(9), 4166-4172. Abstract.  Author URL.
Hamilton PB, Lewis MD, Cruickshank C, Gaunt MW, Yeo M, Llewellyn MS, Valente SA, Maia da Silva F, Stevens JR, Miles MA, et al (2011). Identification and lineage genotyping of South American trypanosomes using fluorescent fragment length barcoding. Infect Genet Evol, 11(1), 44-51. Abstract.  Author URL.
Lange A, Paull GC, Hamilton PB, Iguchi T, Tyler CR (2011). Implications of persistent exposure to treated wastewater effluent for breeding in wild roach (Rutilus rutilus) populations. Environ Sci Technol, 45(4), 1673-1679. Abstract.  Author URL.
Garcia HA, Rodrigues AC, Martinkovic F, Minervino AHH, Campaner M, Nunes VLB, Paiva F, Hamilton PB, Teixeira MMG (2011). Multilocus phylogeographical analysis of Trypanosoma (Megatrypanum) genotypes from sympatric cattle and water buffalo populations supports evolutionary host constraint and close phylogenetic relationships with genotypes found in other ruminants. International Journal for Parasitology, 41(13-14), 1385-1396. Abstract.
Hamilton PB, Stevens JR (2011). Resolving relationships between Australian trypanosomes using DNA barcoding data. Trends Parasitol, 27(3). Author URL.
Harris CA, Hamilton PB, Runnalls TJ, Vinciotti V, Henshaw A, Hodgson D, Coe TS, Jobling S, Tyler CR, Sumpter JP, et al (2011). The consequences of feminization in breeding groups of wild fish. Environ Health Perspect, 119(3), 306-311. Abstract.  Author URL.  Full text.

2010

Adams ER, Hamilton PB, Gibson WC (2010). African trypanosomes: Celebrating diversity. Trends in Parasitology, 26(7), 324-328. Abstract.
Hamilton PB, Stevens, J.R. (2010). Classification and Phylogeny of Trypanosoma cruzi. In Tibayrenc M, Tellería J (Eds.) American Trypanosomiasis, an Elsevier Title.
Paull GC, Filby AL, Giddins HG, Coe TS, Hamilton PB, Tyler CR (2010). Dominance hierarchies in zebrafish (Danio rerio) and their relationship with reproductive success. Zebrafish, 7(1), 109-117. Abstract.  Author URL.
Adams ER, Hamilton PB, Rodrigues AC, Malele II, Delespaux V, Teixeira MMG, Gibson W (2010). New Trypanosoma (Duttonella) vivax genotypes from tsetse flies in East Africa. Parasitology, 137(4), 641-650. Abstract.

2009

Coe TS, Hamilton PB, Griffiths AM, Hodgson DJ, Wahab MA, Tyler CR (2009). Genetic variation in strains of zebrafish (Danio rerio) and the implications for ecotoxicology studies. Ecotoxicology, 18(1), 144-150. Abstract.  Author URL.
Coe TS, Hamilton PB, Hodgson D, Paull GC, Tyler CR (2009). Parentage outcomes in response to estrogen exposure are modified by social grouping in zebrafish. Environ Sci Technol, 43(21), 8400-8405. Abstract.  Author URL.
Hamilton PB, Adams ER, Njiokou F, Gibson WC, Cuny G, Herder S (2009). Phylogenetic analysis reveals the presence of the Trypanosoma cruzi clade in African terrestrial mammals. Infect Genet Evol, 9(1), 81-86. Abstract.  Author URL.

2008

Hamilton PB, Adams ER, Malele II, Gibson WC (2008). A novel, high-throughput technique for species identification reveals a new species of tsetse-transmitted trypanosome related to the Trypanosoma brucei subgenus, Trypanozoon. Infect Genet Evol, 8(1), 26-33. Abstract.  Author URL.
Coe TS, Hamilton PB, Hodgson D, Paull GC, Stevens JR, Sumner K, Tyler CR (2008). An environmental estrogen alters reproductive hierarchies, disrupting sexual selection in group-spawning fish. Environ Sci Technol, 42(13), 5020-5025. Abstract.  Author URL.
Adams ER, Hamilton PB (2008). New molecular tools for the indentification of trypanosome species. Future Microbiology, 3(2), 167-176. Abstract.
Adams ER, Hamilton PB, Malele II, Gibson WC (2008). The identification, diversity and prevalence of trypanosomes in field caught tsetse in Tanzania using ITS-1 primers and fluorescent fragment length barcoding.  Abstract.

2007

Tyler, C.R. (2007). Identification of microsatellite loci for parentage analysis in roach Rutilus rutilus and 8 other cyprinids by cross-species amplification, and a novel test for detecting hybrids between roach and other cyprinids. Molecular Ecology Notes
Hamilton PB, Gibson WC, Stevens JR (2007). Patterns of co-evolution between trypanosomes and their hosts deduced from ribosomal RNA and protein-coding gene phylogenies. Mol Phylogenet Evol, 44(1), 15-25. Abstract.  Author URL.

2006

Hamilton AC, Hamilton PB (eds)(2006). Plant Conservation - an Ecological Approach. London, Earthscan Press. Abstract.

2005

Hamilton P, Stevens, J.R. Gidley, P. Holz, P. Gibson W (2005). A new lineage of trypanosomes from Australian vertebrates and terrestrial bloodsucking leeches (Haemadipsidae). International Journal for Parasitology, 35, 431-443.
Hamilton P, Stevens, J.R. Holz, P. Boag, B. Gibson W (2005). The accidental introduction of the trypanosome of the introduced European rabbit (Oryctolagus cuniculus) to Australia and its potential for biocontrol. Molecular Ecology, 35, 431-443.
Hamilton PB, Stevens JR, Holz P, Boag B, Cooke B, Gibson WC (2005). The inadvertent introduction into Australia of Trypanosoma nabiasi, the trypanosome of the European rabbit (Oryctolagus cuniculus), and its potential for biocontrol. Mol Ecol, 14(10), 3167-3175. Abstract.  Author URL.

2004

Hamilton P, Stevens, J.R. Gaunt, M.W. Gidley, J. Gibson W (2004). Trypanosomes are monophyletic: evidence from genes for glyceraldehyde phosphate dehydrogenase and small subunit ribosomal RNA. International Journal for Parasitology, 34, 1393-1404.

Patrick_Hamilton Details from cache as at 2018-09-19 00:33:04

Refresh publications

Invited lectures:

8th  International  Symposium  on  Fish  Endocrinology,  Gothenberg,  Sweden 28th June-2nd of July 2016 - Invited speaker

TryTax2  June  14 -16,  2016  in  Ostrava,  Czech  Republic Invited  keynote  speaker:

Towards understanding  the  origin  of Trypanosoma  cruzi (also  a session  chair  and  member  of

the  Scientific Organising Committee).

SETAC Europe Nantes May 25th, 2016 “Addressing whether roach in English rivers have adapted to the harmful effects of exposure to oestrogenic wastewater treatment work effluents” - Oral  presentation

SETAC North America 35th Annual meeting Vancouver, Canada 9-13th November 2014 Are roach populations living in UK Rivers adversely affected through exposure to environmental oestrogens? – oral presentation

I am an associate fellow of the Higher Education Academy.  I am currently involved in teaching on the following undergraduate modules:

BIO2066/BIO2068 (Forensic Science): Module leader

BIO1332 (Biochemistry)

BIO1334 (Genetics)

BIO1337 (Microbiology)

BIO1339 (Cells)

BIO2078: (Medical and General Microbiology)

I am also a tutor for first-year undergraduates and supervise two final year students.

 

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