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Dr Steven West

Dr Steven West

Associate Professor, Molecular Biology

 7458

 +44 (0)1392 727458

 Living Systems Institute T05.12

 

Living Systems Institute, University of Exeter, Stocker Road, Exeter, EX4 4QD

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Eaton JD, Davidson L, Bauer DLV, Natsume T, Kanemaki MT, West S (In Press). Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity. Genes Dev, 32(2), 127-139. Abstract.  Author URL.
Muniz L, Davidson L, West S (2015). Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs. MOLECULAR AND CELLULAR BIOLOGY, 35(13), 2218-2230. Author URL.
Davidson L, Muniz L, West S (2014). 3 ' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells. GENES & DEVELOPMENT, 28(4), 342-356. Author URL.
Hett A, West S (2014). Inhibition of U4 snRNA in Human Cells Causes the Stable Retention of Polyadenylated Pre-mRNA in the Nucleus. PLOS ONE, 9(5). Author URL.
Davidson L, West S (2013). Splicing-coupled 3' end formation requires a terminal splice acceptor site, but not intron excision. NUCLEIC ACIDS RESEARCH, 41(14), 7101-7114. Author URL.
Davidson L, Kerr A, West S (2012). Co-transcriptional degradation of aberrant pre-mRNA by Xrn2. EMBO JOURNAL, 31(11), 2566-2578. Author URL.
West S (2012). The increasing functional repertoire of U1 snRNA. BIOCHEMICAL SOCIETY TRANSACTIONS, 40, 846-849. Author URL.
Schmidt M-J, West S, Norbury CJ (2011). The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation. RNA-A PUBLICATION OF THE RNA SOCIETY, 17(1), 39-44. Author URL.
West S, Proudfoot NJ (2009). Transcriptional Termination Enhances Protein Expression in Human Cells. MOLECULAR CELL, 33(3), 354-364. Author URL.
West S, Proudfoot NJ (2008). Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination. NUCLEIC ACIDS RESEARCH, 36(3), 905-914. Author URL.
West S, Proudfoot NJ, Dye MJ (2008). Molecular dissection of mammalian RNA polymerase II transcriptional termination. MOLECULAR CELL, 29(5), 600-610. Author URL.
Gromak N, West S, Proudfoot NJ (2006). Pause sites promote transcriptional termination of mammalian RNA polymerase II. MOLECULAR AND CELLULAR BIOLOGY, 26(10), 3986-3996. Author URL.
West S, Zaret K, Proudfoot NJ (2006). Transcriptional termination sequences in the mouse serum albumin gene. RNA, 12(4), 655-665. Abstract.  Author URL.
Dye MJ, Gromak N, Haussecker D, West S, Proudfoot NJ (2006). Turnover and function of noncoding RNA polymerase II transcripts. Cold Spring Harb Symp Quant Biol, 71, 275-284. Abstract.  Author URL.
Teixeira A, Tahiri-Alaoui A, West S, Thomas B, Ramadass A, Martianov I, Dye M, James W, Proudfoot NJ, Akoulitchev A, et al (2004). Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination. Nature, 432(7016), 526-530. Abstract.  Author URL.
West S, Gromak N, Proudfoot NJ (2004). Human 5 '-> 3 ' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites. NATURE, 432(7016), 522-525. Author URL.

Publications by year


In Press

Eaton JD, Davidson L, Bauer DLV, Natsume T, Kanemaki MT, West S (In Press). Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity. Genes Dev, 32(2), 127-139. Abstract.  Author URL.

2015

Muniz L, Davidson L, West S (2015). Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs. MOLECULAR AND CELLULAR BIOLOGY, 35(13), 2218-2230. Author URL.

2014

Davidson L, Muniz L, West S (2014). 3 ' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells. GENES & DEVELOPMENT, 28(4), 342-356. Author URL.
Hett A, West S (2014). Inhibition of U4 snRNA in Human Cells Causes the Stable Retention of Polyadenylated Pre-mRNA in the Nucleus. PLOS ONE, 9(5). Author URL.

2013

Davidson L, West S (2013). Splicing-coupled 3' end formation requires a terminal splice acceptor site, but not intron excision. NUCLEIC ACIDS RESEARCH, 41(14), 7101-7114. Author URL.

2012

Davidson L, Kerr A, West S (2012). Co-transcriptional degradation of aberrant pre-mRNA by Xrn2. EMBO JOURNAL, 31(11), 2566-2578. Author URL.
West S (2012). The increasing functional repertoire of U1 snRNA. BIOCHEMICAL SOCIETY TRANSACTIONS, 40, 846-849. Author URL.

2011

Schmidt M-J, West S, Norbury CJ (2011). The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation. RNA-A PUBLICATION OF THE RNA SOCIETY, 17(1), 39-44. Author URL.

2009

West S, Proudfoot NJ (2009). Transcriptional Termination Enhances Protein Expression in Human Cells. MOLECULAR CELL, 33(3), 354-364. Author URL.

2008

West S, Proudfoot NJ (2008). Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination. NUCLEIC ACIDS RESEARCH, 36(3), 905-914. Author URL.
West S, Proudfoot NJ, Dye MJ (2008). Molecular dissection of mammalian RNA polymerase II transcriptional termination. MOLECULAR CELL, 29(5), 600-610. Author URL.

2006

Gromak N, West S, Proudfoot NJ (2006). Pause sites promote transcriptional termination of mammalian RNA polymerase II. MOLECULAR AND CELLULAR BIOLOGY, 26(10), 3986-3996. Author URL.
West S, Zaret K, Proudfoot NJ (2006). Transcriptional termination sequences in the mouse serum albumin gene. RNA, 12(4), 655-665. Abstract.  Author URL.
Dye MJ, Gromak N, Haussecker D, West S, Proudfoot NJ (2006). Turnover and function of noncoding RNA polymerase II transcripts. Cold Spring Harb Symp Quant Biol, 71, 275-284. Abstract.  Author URL.

2004

Teixeira A, Tahiri-Alaoui A, West S, Thomas B, Ramadass A, Martianov I, Dye M, James W, Proudfoot NJ, Akoulitchev A, et al (2004). Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination. Nature, 432(7016), 526-530. Abstract.  Author URL.
West S, Gromak N, Proudfoot NJ (2004). Human 5 '-> 3 ' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites. NATURE, 432(7016), 522-525. Author URL.

Steven_West Details from cache as at 2018-12-10 09:33:50

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