Dr Eduarda Santos
Senior Lecturer in Environmental Biology

Key publications | Publications by category | Publications by year

Key publications



Laing LV, Viana J, Dempster EL, Trznadel M, Trunkfield LA, Uren Webster TM, van Aerle R, Paull GC, Wilson RJ, Mill J, et al (In Press). Bisphenol a causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio). Epigenetics, 11(7), 526-538. Abstract.  Author URL.  Full text. DOI.
Fitzgerald JA, Jameson HM, Fowler VHD, Bond GL, Bickley LK, Webster TMU, Bury NR, Wilson RJ, Santos EM (2016). Hypoxia Suppressed Copper Toxicity during Early Development in Zebrafish Embryos in a Process Mediated by the Activation of the HIF Signaling Pathway. Environ Sci Technol, 50(8), 4502-4512. Abstract.  Author URL.  Full text. DOI.
Verbruggen B, Bickley LK, van Aerle R, Bateman KS, Stentiford GD, Santos EM, Tyler CR (2016). Molecular Mechanisms of White Spot Syndrome Virus Infection and Perspectives on Treatments. Viruses, 8(1). Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Santos EM (2015). Global transcriptomic profiling demonstrates induction of oxidative stress and of compensatory cellular stress responses in brown trout exposed to glyphosate and Roundup. BMC Genomics, 16 Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Perry MH, Santos EM (2015). The herbicide linuron inhibits cholesterol biosynthesis and induces cellular stress responses in brown trout. Environ Sci Technol, 49(5), 3110-3118. Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Laing LV, Florance H, Santos EM (2014). Effects of glyphosate and its formulation, roundup, on reproduction in zebrafish (Danio rerio). Environ Sci Technol, 48(2), 1271-1279. Abstract.  Author URL.  Full text. DOI.

Publications by category


Journal articles

Laing LV, Viana J, Dempster EL, Trznadel M, Trunkfield LA, Uren Webster TM, van Aerle R, Paull GC, Wilson RJ, Mill J, et al (In Press). Bisphenol a causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio). Epigenetics, 11(7), 526-538. Abstract.  Author URL.  Full text. DOI.
van Aerle R, Santos EM (2017). Advances in the application of high-throughput sequencing in invertebrate virology. J Invertebr Pathol, 147, 145-156. Abstract.  Author URL. DOI.
Bickley LK, van Aerle R, Brown AR, Hargreaves A, Huby R, Cammack V, Jackson R, Santos EM, Tyler CR (2017). Bioavailability and Kidney Responses to Diclofenac in the Fathead Minnow (Pimephales promelas). Environ Sci Technol, 51(3), 1764-1774. Abstract.  Author URL.  Full text. DOI.
Fitzgerald JA, Katsiadaki I, Santos EM (2017). Contrasting effects of hypoxia on copper toxicity during development in the three-spined stickleback (Gasterosteus aculeatus). Environ Pollut, 222, 433-443. Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Williams TD, Katsiadaki I, Lange A, Lewis C, Shears JA, Tyler CR, Santos EM (2017). Hepatic transcriptional responses to copper in the three-spined stickleback are affected by their pollution exposure history. Aquat Toxicol, 184, 26-36. Abstract.  Author URL.  Full text. DOI.
Fitzgerald JA, Jameson HM, Fowler VHD, Bond GL, Bickley LK, Webster TMU, Bury NR, Wilson RJ, Santos EM (2016). Hypoxia Suppressed Copper Toxicity during Early Development in Zebrafish Embryos in a Process Mediated by the Activation of the HIF Signaling Pathway. Environ Sci Technol, 50(8), 4502-4512. Abstract.  Author URL.  Full text. DOI.
Verbruggen B, Bickley LK, van Aerle R, Bateman KS, Stentiford GD, Santos EM, Tyler CR (2016). Molecular Mechanisms of White Spot Syndrome Virus Infection and Perspectives on Treatments. Viruses, 8(1). Abstract.  Author URL.  Full text. DOI.
Verbruggen B, Bickley LK, Santos EM, Tyler CR, Stentiford GD, Bateman KS, van Aerle R (2015). De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways. BMC Genomics, 16 Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Santos EM (2015). Global transcriptomic profiling demonstrates induction of oxidative stress and of compensatory cellular stress responses in brown trout exposed to glyphosate and Roundup. BMC Genomics, 16 Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Shears JA, Moore K, Santos EM (2015). Identification of conserved hepatic transcriptomic responses to 17β-estradiol using high-throughput sequencing in brown trout. Physiol Genomics, 47(9), 420-431. Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Perry MH, Santos EM (2015). The herbicide linuron inhibits cholesterol biosynthesis and induces cellular stress responses in brown trout. Environ Sci Technol, 49(5), 3110-3118. Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Laing LV, Florance H, Santos EM (2014). Effects of glyphosate and its formulation, roundup, on reproduction in zebrafish (Danio rerio). Environ Sci Technol, 48(2), 1271-1279. Abstract.  Author URL.  Full text. DOI.
Santos E, Webster TU (2014). Secrets of cornwall's metal-tolerant trout. Planet Earth(SPRING), 28-29.
Uren Webster TM, Bury N, van Aerle R, Santos EM (2013). Global transcriptome profiling reveals molecular mechanisms of metal tolerance in a chronically exposed wild population of brown trout. Environ Sci Technol, 47(15), 8869-8877. Abstract.  Author URL.  Full text. DOI.
van Aerle R, Lange A, Moorhouse A, Paszkiewicz K, Ball K, Johnston BD, de-Bastos E, Booth T, Tyler CR, Santos EM, et al (2013). Molecular mechanisms of toxicity of silver nanoparticles in zebrafish embryos. Environ Sci Technol, 47(14), 8005-8014. Abstract.  Author URL.  Full text. DOI.
Santos EM, Hamilton PB, Coe TS, Ball JS, Cook AC, Katsiadaki I, Tyler CR (2013). Population bottlenecks, genetic diversity and breeding ability of the three-spined stickleback (Gasterosteus aculeatus) from three polluted English Rivers. Aquatic Toxicology, 142-143, 264-271. Abstract. DOI.
Fu J, Han J, Zhou B, Gong Z, Santos EM, Huo X, Zheng W, Liu H, Yu H, Liu C, et al (2013). Toxicogenomic responses of zebrafish embryos/larvae to tris(1,3-dichloro-2-propyl) phosphate (TDCPP) reveal possible molecular mechanisms of developmental toxicity. Environ Sci Technol, 47(18), 10574-10582. Abstract.  Author URL. DOI.
Al-Jandal NJ, Whittamore JM, Santos EM, Wilson RW (2011). The influence of 17β-estradiol on intestinal calcium carbonate precipitation and osmoregulation in seawater-acclimated rainbow trout (Oncorhynchus mykiss). J Exp Biol, 214(Pt 16), 2791-2798. Abstract.  Author URL. DOI.
Scown TM, Santos EM, Johnston BD, Gaiser B, Baalousha M, Mitov S, Lead JR, Stone V, Fernandes TF, Jepson M, et al (2010). Effects of aqueous exposure to silver nanoparticles of different sizes in rainbow trout. Toxicol Sci, 115(2), 521-534. Abstract.  Author URL. DOI.
Katsiadaki I, Williams TD, Ball JS, Bean TP, Sanders MB, Wu H, Santos EM, Brown MM, Baker P, Ortega F, et al (2010). Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol. Aquat Toxicol, 97(3), 174-187. Abstract.  Author URL. DOI.
Santos EM, Ball JS, Williams TD, Wu H, Ortega F, van Aerle R, Katsiadaki I, Falciani F, Viant MR, Chipman JK, et al (2010). Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model. Environ Sci Technol, 44(2), 820-826. Abstract.  Author URL. DOI.
Van Aggelen G, Ankley GT, Baldwin WS, Bearden DW, Benson WH, Chipman JK, Collette TW, Craft JA, Denslow ND, Embry MR, et al (2010). Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook. Environ Health Perspect, 118(1), 1-5. Abstract.  Author URL. DOI.
Uren-Webster TM, Lewis C, Filby AL, Paull GC, Santos EM (2010). Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish. Aquat Toxicol, 99(3), 360-369. Abstract.  Author URL. DOI.
Oehlmann J, Schulte-Oehlmann U, Kloas W, Jagnytsch O, Lutz I, Kusk KO, Wollenberger L, Santos EM, Paull GC, VanLook KJW, et al (2009). A critical analysis of the biological impacts of plasticizers on wildlife. Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1526), 2047-2062. Abstract. DOI.
Williams TD, Wu H, Santos EM, Ball J, Katsiadaki I, Brown MM, Baker P, Ortega F, Falciani F, Craft JA, et al (2009). Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene. Environ Sci Technol, 43(16), 6341-6348. Abstract.  Author URL.
Williams TD, Brown M, Chipman JK, Falciani F, Ortega F, Geoghegan F, Craft JA, Katsiadaki I, Ball J, Tyler CR, et al (2008). Development of a stickleback (Gasterosteus aculeatus) cDNA microarray and gene expression responses to dibenzanthracene, ethinyl-estradiol and copper. MARINE ENVIRONMENTAL RESEARCH, 66(1), 140-140. Author URL.
Santos EM, Kille P, Workman VL, Paull GC, Tyler CR (2008). Sexually dimorphic gene expression in the brains of mature zebrafish. Comp Biochem Physiol a Mol Integr Physiol, 149(3), 314-324. Abstract.  Author URL. DOI.
Paull GC, Van Look KJW, Santos EM, Filby AL, Gray DM, Nash JP, Tyler CR (2008). Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals. Aquat Toxicol, 87(2), 115-126. Abstract.  Author URL. DOI.
Filby AL, Santos EM, Thorpe KL, Maack G, Tyler CR (2007). Gene expression profiling for understanding chemical causation of biological effects for complex mixtures: a case study on estrogens. Environ Sci Technol, 41(23), 8187-8194. Abstract.  Author URL.
Santos EM, Paull GC, Van Look KJW, Workman VL, Holt WV, van Aerle R, Kille P, Tyler CR (2007). Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio). Aquat Toxicol, 83(2), 134-142. Abstract.  Author URL. DOI.
Santos EM, Workman VL, Paull GC, Filby AL, Van Look KJW, Kille P, Tyler CR (2007). Molecular basis of sex and reproductive status in breeding zebrafish. Physiol Genomics, 30(2), 111-122. Abstract.  Author URL. DOI.
Tyler C, Lange A, Santos E, Filby A (2007). The application of transcriptomics and other molecular approaches in advancing our understanding of endocrine disruption. TOXICOLOGY LETTERS, 172, S27-S27. Author URL. DOI.
Santos E, Paull G, Filby A, Tyler C, Van Look K, Holt W, Workman V, Kille P (2006). Gender and stage-specific transcriptomic profiles of gonads and brains in breeding zebrafish. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 143(4), S101-S101. Author URL.
Tyler CR, Spary C, Gibson R, Santos EM, Shears J, Hill EM (2005). Accounting for differences in estrogenic responses in rainbow trout (Oncorhynchus mykiss: Salmonidae) and roach (Rutilus rutilus: Cyprinidae) exposed to effluents from wastewater treatment works. Environ Sci Technol, 39(8), 2599-2607. Abstract.  Author URL.
Williams, R. Johnson, A. (2005). Predicted exposures to steroid estrogens in UK Rivers correlate with widespread sexual disruption in wild fish populations. Environmental Health Perspectives, 32-39.
Tyler CR, van Aerle R, Santos EM (2004). ELISAs for detecting vitellogenin in the fathead minnow (Pimephales promelas)-a critical analysis. Response to Mylchreest et al. Comp Biochem Physiol C 134: 251-257, 2003. Comp Biochem Physiol C Toxicol Pharmacol, 138(4), 531-532. Author URL. DOI.
Santos EM, Rand-Weaver M, Tyler CR (2001). Follicle-stimulating hormone and its alpha and beta subunits in rainbow trout (Oncorhynchus mykiss): purification, characterization, development of specific radioimmunoassays, and their seasonal plasma and pituitary concentrations in females. Biol Reprod, 65(1), 288-294. Abstract.  Author URL.
Cavaco, J.E.B. Rebers, F.E.M. Vischer, H.F. (2001). Gonadotrophins, their receptors, and regulation of testicular functions in fish. Comparative Biochemistry and Physiology Part B, 129, 407-417.
Harris CA, Santos EM, Janbakhsh A, Pottinger TG, Tyler CR, Sumpter JP (2001). Nonylphenol affects gonadotropin levels in the pituitary gland and plasma of female rainbow trout. Environ Sci Technol, 35(14), 2909-2916. Abstract.  Author URL.
Tyler CR, Pottinger TG, Santos E, Sumpter JP, Price SA, Brooks S, Nagler JJ (1996). Mechanisms controlling egg size and number in the rainbow trout, Oncorhynchus mykiss. Biol Reprod, 54(1), 8-15. Abstract.  Author URL.

Chapters

Lewis C, Santos EM (2016). Physiological impacts of chemical pollutants in marine animals. In Solan M, Whiteley N (Eds.) Stressors in the Marine Environment, Oxford University Press, 73-92.
Tyler CR, Filby AL, van Aerle R, Lange A, Ball J, Santos EM (2008). Fish toxicogenomics. In  (Ed) Advances in Experimental Biology, Elsevier.

Conferences

Tyler C, Lange A, Santos E, Coe T, Paull G, Filby A, Hamilton P (2008). The feminization of fish in English rivers: Causation, mechanisms, and significance.  Author URL.
Tyler CR, Ball J, Maack G, Paull G, Santos EM (2002). Endocrine disruption in vertebrate wildlife - Today's story.  Author URL.
Schulz RW, Vischer HF, Cavaco JEB, Santos EM, Tyler CR, Goos HJT, Bogerd J (2001). Gonadotropins, their receptors, and the regulation of testicular functions in fish.  Author URL. DOI.

Publications by year



In Press

Laing LV, Viana J, Dempster EL, Trznadel M, Trunkfield LA, Uren Webster TM, van Aerle R, Paull GC, Wilson RJ, Mill J, et al (In Press). Bisphenol a causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio). Epigenetics, 11(7), 526-538. Abstract.  Author URL.  Full text. DOI.

2017

van Aerle R, Santos EM (2017). Advances in the application of high-throughput sequencing in invertebrate virology. J Invertebr Pathol, 147, 145-156. Abstract.  Author URL. DOI.
Bickley LK, van Aerle R, Brown AR, Hargreaves A, Huby R, Cammack V, Jackson R, Santos EM, Tyler CR (2017). Bioavailability and Kidney Responses to Diclofenac in the Fathead Minnow (Pimephales promelas). Environ Sci Technol, 51(3), 1764-1774. Abstract.  Author URL.  Full text. DOI.
Fitzgerald JA, Katsiadaki I, Santos EM (2017). Contrasting effects of hypoxia on copper toxicity during development in the three-spined stickleback (Gasterosteus aculeatus). Environ Pollut, 222, 433-443. Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Williams TD, Katsiadaki I, Lange A, Lewis C, Shears JA, Tyler CR, Santos EM (2017). Hepatic transcriptional responses to copper in the three-spined stickleback are affected by their pollution exposure history. Aquat Toxicol, 184, 26-36. Abstract.  Author URL.  Full text. DOI.

2016

Fitzgerald JA, Jameson HM, Fowler VHD, Bond GL, Bickley LK, Webster TMU, Bury NR, Wilson RJ, Santos EM (2016). Hypoxia Suppressed Copper Toxicity during Early Development in Zebrafish Embryos in a Process Mediated by the Activation of the HIF Signaling Pathway. Environ Sci Technol, 50(8), 4502-4512. Abstract.  Author URL.  Full text. DOI.
Verbruggen B, Bickley LK, van Aerle R, Bateman KS, Stentiford GD, Santos EM, Tyler CR (2016). Molecular Mechanisms of White Spot Syndrome Virus Infection and Perspectives on Treatments. Viruses, 8(1). Abstract.  Author URL.  Full text. DOI.
Lewis C, Santos EM (2016). Physiological impacts of chemical pollutants in marine animals. In Solan M, Whiteley N (Eds.) Stressors in the Marine Environment, Oxford University Press, 73-92.

2015

Verbruggen B, Bickley LK, Santos EM, Tyler CR, Stentiford GD, Bateman KS, van Aerle R (2015). De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways. BMC Genomics, 16 Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Santos EM (2015). Global transcriptomic profiling demonstrates induction of oxidative stress and of compensatory cellular stress responses in brown trout exposed to glyphosate and Roundup. BMC Genomics, 16 Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Shears JA, Moore K, Santos EM (2015). Identification of conserved hepatic transcriptomic responses to 17β-estradiol using high-throughput sequencing in brown trout. Physiol Genomics, 47(9), 420-431. Abstract.  Author URL.  Full text. DOI.
Uren Webster TM, Perry MH, Santos EM (2015). The herbicide linuron inhibits cholesterol biosynthesis and induces cellular stress responses in brown trout. Environ Sci Technol, 49(5), 3110-3118. Abstract.  Author URL.  Full text. DOI.

2014

Uren Webster TM, Laing LV, Florance H, Santos EM (2014). Effects of glyphosate and its formulation, roundup, on reproduction in zebrafish (Danio rerio). Environ Sci Technol, 48(2), 1271-1279. Abstract.  Author URL.  Full text. DOI.
Santos E, Webster TU (2014). Secrets of cornwall's metal-tolerant trout. Planet Earth(SPRING), 28-29.

2013

Uren Webster TM, Bury N, van Aerle R, Santos EM (2013). Global transcriptome profiling reveals molecular mechanisms of metal tolerance in a chronically exposed wild population of brown trout. Environ Sci Technol, 47(15), 8869-8877. Abstract.  Author URL.  Full text. DOI.
van Aerle R, Lange A, Moorhouse A, Paszkiewicz K, Ball K, Johnston BD, de-Bastos E, Booth T, Tyler CR, Santos EM, et al (2013). Molecular mechanisms of toxicity of silver nanoparticles in zebrafish embryos. Environ Sci Technol, 47(14), 8005-8014. Abstract.  Author URL.  Full text. DOI.
Santos EM, Hamilton PB, Coe TS, Ball JS, Cook AC, Katsiadaki I, Tyler CR (2013). Population bottlenecks, genetic diversity and breeding ability of the three-spined stickleback (Gasterosteus aculeatus) from three polluted English Rivers. Aquatic Toxicology, 142-143, 264-271. Abstract. DOI.
Fu J, Han J, Zhou B, Gong Z, Santos EM, Huo X, Zheng W, Liu H, Yu H, Liu C, et al (2013). Toxicogenomic responses of zebrafish embryos/larvae to tris(1,3-dichloro-2-propyl) phosphate (TDCPP) reveal possible molecular mechanisms of developmental toxicity. Environ Sci Technol, 47(18), 10574-10582. Abstract.  Author URL. DOI.

2011

Al-Jandal NJ, Whittamore JM, Santos EM, Wilson RW (2011). The influence of 17β-estradiol on intestinal calcium carbonate precipitation and osmoregulation in seawater-acclimated rainbow trout (Oncorhynchus mykiss). J Exp Biol, 214(Pt 16), 2791-2798. Abstract.  Author URL. DOI.

2010

Scown TM, Santos EM, Johnston BD, Gaiser B, Baalousha M, Mitov S, Lead JR, Stone V, Fernandes TF, Jepson M, et al (2010). Effects of aqueous exposure to silver nanoparticles of different sizes in rainbow trout. Toxicol Sci, 115(2), 521-534. Abstract.  Author URL. DOI.
Katsiadaki I, Williams TD, Ball JS, Bean TP, Sanders MB, Wu H, Santos EM, Brown MM, Baker P, Ortega F, et al (2010). Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol. Aquat Toxicol, 97(3), 174-187. Abstract.  Author URL. DOI.
Santos EM, Ball JS, Williams TD, Wu H, Ortega F, van Aerle R, Katsiadaki I, Falciani F, Viant MR, Chipman JK, et al (2010). Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model. Environ Sci Technol, 44(2), 820-826. Abstract.  Author URL. DOI.
Van Aggelen G, Ankley GT, Baldwin WS, Bearden DW, Benson WH, Chipman JK, Collette TW, Craft JA, Denslow ND, Embry MR, et al (2010). Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook. Environ Health Perspect, 118(1), 1-5. Abstract.  Author URL. DOI.
Uren-Webster TM, Lewis C, Filby AL, Paull GC, Santos EM (2010). Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish. Aquat Toxicol, 99(3), 360-369. Abstract.  Author URL. DOI.

2009

Oehlmann J, Schulte-Oehlmann U, Kloas W, Jagnytsch O, Lutz I, Kusk KO, Wollenberger L, Santos EM, Paull GC, VanLook KJW, et al (2009). A critical analysis of the biological impacts of plasticizers on wildlife. Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1526), 2047-2062. Abstract. DOI.
Williams TD, Wu H, Santos EM, Ball J, Katsiadaki I, Brown MM, Baker P, Ortega F, Falciani F, Craft JA, et al (2009). Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene. Environ Sci Technol, 43(16), 6341-6348. Abstract.  Author URL.

2008

Williams TD, Brown M, Chipman JK, Falciani F, Ortega F, Geoghegan F, Craft JA, Katsiadaki I, Ball J, Tyler CR, et al (2008). Development of a stickleback (Gasterosteus aculeatus) cDNA microarray and gene expression responses to dibenzanthracene, ethinyl-estradiol and copper. MARINE ENVIRONMENTAL RESEARCH, 66(1), 140-140. Author URL.
Tyler CR, Filby AL, van Aerle R, Lange A, Ball J, Santos EM (2008). Fish toxicogenomics. In  (Ed) Advances in Experimental Biology, Elsevier.
Santos EM, Kille P, Workman VL, Paull GC, Tyler CR (2008). Sexually dimorphic gene expression in the brains of mature zebrafish. Comp Biochem Physiol a Mol Integr Physiol, 149(3), 314-324. Abstract.  Author URL. DOI.
Tyler C, Lange A, Santos E, Coe T, Paull G, Filby A, Hamilton P (2008). The feminization of fish in English rivers: Causation, mechanisms, and significance.  Author URL.
Paull GC, Van Look KJW, Santos EM, Filby AL, Gray DM, Nash JP, Tyler CR (2008). Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals. Aquat Toxicol, 87(2), 115-126. Abstract.  Author URL. DOI.

2007

Filby AL, Santos EM, Thorpe KL, Maack G, Tyler CR (2007). Gene expression profiling for understanding chemical causation of biological effects for complex mixtures: a case study on estrogens. Environ Sci Technol, 41(23), 8187-8194. Abstract.  Author URL.
Santos EM, Paull GC, Van Look KJW, Workman VL, Holt WV, van Aerle R, Kille P, Tyler CR (2007). Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio). Aquat Toxicol, 83(2), 134-142. Abstract.  Author URL. DOI.
Santos EM, Workman VL, Paull GC, Filby AL, Van Look KJW, Kille P, Tyler CR (2007). Molecular basis of sex and reproductive status in breeding zebrafish. Physiol Genomics, 30(2), 111-122. Abstract.  Author URL. DOI.
Tyler C, Lange A, Santos E, Filby A (2007). The application of transcriptomics and other molecular approaches in advancing our understanding of endocrine disruption. TOXICOLOGY LETTERS, 172, S27-S27. Author URL. DOI.

2006

Santos E, Paull G, Filby A, Tyler C, Van Look K, Holt W, Workman V, Kille P (2006). Gender and stage-specific transcriptomic profiles of gonads and brains in breeding zebrafish. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 143(4), S101-S101. Author URL.

2005

Tyler CR, Spary C, Gibson R, Santos EM, Shears J, Hill EM (2005). Accounting for differences in estrogenic responses in rainbow trout (Oncorhynchus mykiss: Salmonidae) and roach (Rutilus rutilus: Cyprinidae) exposed to effluents from wastewater treatment works. Environ Sci Technol, 39(8), 2599-2607. Abstract.  Author URL.
Williams, R. Johnson, A. (2005). Predicted exposures to steroid estrogens in UK Rivers correlate with widespread sexual disruption in wild fish populations. Environmental Health Perspectives, 32-39.

2004

Tyler CR, van Aerle R, Santos EM (2004). ELISAs for detecting vitellogenin in the fathead minnow (Pimephales promelas)-a critical analysis. Response to Mylchreest et al. Comp Biochem Physiol C 134: 251-257, 2003. Comp Biochem Physiol C Toxicol Pharmacol, 138(4), 531-532. Author URL. DOI.

2002

Tyler CR, Ball J, Maack G, Paull G, Santos EM (2002). Endocrine disruption in vertebrate wildlife - Today's story.  Author URL.

2001

Santos EM, Rand-Weaver M, Tyler CR (2001). Follicle-stimulating hormone and its alpha and beta subunits in rainbow trout (Oncorhynchus mykiss): purification, characterization, development of specific radioimmunoassays, and their seasonal plasma and pituitary concentrations in females. Biol Reprod, 65(1), 288-294. Abstract.  Author URL.
Cavaco, J.E.B. Rebers, F.E.M. Vischer, H.F. (2001). Gonadotrophins, their receptors, and regulation of testicular functions in fish. Comparative Biochemistry and Physiology Part B, 129, 407-417.
Schulz RW, Vischer HF, Cavaco JEB, Santos EM, Tyler CR, Goos HJT, Bogerd J (2001). Gonadotropins, their receptors, and the regulation of testicular functions in fish.  Author URL. DOI.
Harris CA, Santos EM, Janbakhsh A, Pottinger TG, Tyler CR, Sumpter JP (2001). Nonylphenol affects gonadotropin levels in the pituitary gland and plasma of female rainbow trout. Environ Sci Technol, 35(14), 2909-2916. Abstract.  Author URL.

1996

Tyler CR, Pottinger TG, Santos E, Sumpter JP, Price SA, Brooks S, Nagler JJ (1996). Mechanisms controlling egg size and number in the rainbow trout, Oncorhynchus mykiss. Biol Reprod, 54(1), 8-15. Abstract.  Author URL.