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Dr Stephen Michell

Dr Stephen Michell

Senior Lecturer in Molecular Microbiology

 5524

 Geoffrey Pope 405

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

 Office hours:

9.30 to 10.30 Mondays

1.30 to 2.30 Wednesdays

2.30 to 3.30 Fridays

Dr Stephen Michell working in the lab

Dr Stephen Michell working in the lab

Overview

I am a molecular microbiologist with interests in the the virulence mechanisms of pathogenic bacteria. My research has focused on the post-translational modification of bacterial proteins and into the development of genetic tools for the manipulation of hazardous pathogens. My lab looks predominantly at secreted proteins, focusing on lipoproteins. We study both Gram negative and positive bacteria, with the aim of characterising novel virulence factors. I am a member of the Microbes and Disease research group.

Qualifications

1993: BSc, Chemistry and Biochemistry, Imperial College.
1999: PhD, St. Mary's Hospital, Imperial College.
2011: Fellow of the Higher Education Academy

Career

2012-Present Senior Lecturer of Molecular Microbiology, School of Biosciences, University of Exeter
2007-2012: Lecturer of Molecular Microbiology, School of Biosciences, University of Exeter
2002-2007: Research Scientist at the Defence Science Technology Laboratories
1994-2002: Research Scientist at the Veterinary Laboratories Agency

Links

Research group links

Dr Stephen Michell

Dr Stephen Michell

Research

Research interests

My research aims to identify and characterise novel virulence factors from human pathogens to further understand mechanisms of bacterial pathogenesis. One area of particular interest is bacterial post-translational modification. Several pathogens secrete proteins which are acylated or glycosylated, or both, and function as virulence factors. Understanding the mechanisms by which pathogens modify their proteins and the contribution of these modifications to disease is the main focus of my research. I also have an interest in whole genome sequencing of bacterial pathogens as an approach to identifying novel virulence factors.

Current projects include study of the mechanism of protein acylation by Clostridium difficle and its role in virulence. Identification of novel virulence factors of Vibrio vulnificus. I also have collaborative research projects with Professor Rick Titball looking at Burkholderia pseudomallei and Coxiella Burnetti.

Collaborators

  • Prof Neil Fairweather – Imperial College
  • Prof Nigel Minton – University of Nottingham
  • De Ed Tate – Imperial College
  • Dr Craig Baker-Austin – CEFAS
  • Dr Rosanna Leuzzi – Novartis, Siena
  • Dr Paolo Landini – University of Milan
  • Dr Mona Bajaj-Elliot – University College London
  • Dr Ray Sheridan -Royal Devon & Exeter Hospital
  • Dr Ed Keedwell – CEMPS, University of Exeter

Research grants

  • 2016 NERC
    Development of a diagnostic tool for the identification of Vibrio vulnificus strains associated with disease.
  • 2016 Saved and Safe
    Saved and Safe. Project to develop molecular diagnostics for bovine tuberculosis
  • 2011 Cefas and University of Exeter
    Insights into pathogenesis and virulence using targeted gene disruption of the pathogens Vibrio parahaemolyticus and vulnificus
  • 2010 PenCLARHC
    Exploring the potential for the development of a DNA based diagnostic for Clostridium difficile to indicate probability of relapse
  • 2010 CARIPLO
    From Genome to Antigen
  • 2009 Defence Science and Technology Laboratory
    Galleria Models for Assessing Virulence of B. pseudomallei
  • 2007 Defence Science and Technology Laboratory
    Identification of Genes Involved in Resistance to Bacterial Infection

Publications

Key publications | Publications by category | Publications by year

Key publications


Church SR, Lux T, Baker-Austin C, Buddington SP, Michell SL (2016). Vibrio vulnificus Type 6 Secretion System 1 Contains Anti-Bacterial Properties. PLoS One, 11(10). Abstract.  Author URL.  Full text.
Nandi T, Holden MTG, Didelot X, Mehershahi K, Boddey JA, Beacham I, Peak I, Harting J, Baybayan P, Guo Y, et al (2015). Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles. Genome Res, 25(1), 129-141. Abstract.  Author URL.
Charlton TM, Kovacs-Simon A, Michell SL, Fairweather NF, Tate EW (2015). Quantitative Lipoproteomics in Clostridium difficile Reveals a Role for Lipoproteins in Sporulation. CHEMISTRY & BIOLOGY, 22(11), 1562-1573. Author URL.  Full text.
Kovacs-Simon A, Leuzzi R, Kasendra M, Minton N, Titball RW, Michell SL (2014). Lipoprotein CD0873 is a novel adhesin of Clostridium difficile. J Infect Dis, 210(2), 274-284. Abstract.  Author URL.
He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, et al (2012). Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nature Genetics
Thomas RM, Twine SM, Fulton KM, Tessier L, Kilmury SLN, Ding W, Harmer N, Michell SL, Oyston PCF, Titball RW, et al (2011). Glycosylation of DsbA in Francisella tularensis subsp. tularensis. J Bacteriol, 193(19), 5498-5509. Abstract.  Author URL.

Publications by category


Journal articles

Church SR, Lux T, Baker-Austin C, Buddington SP, Michell SL (2016). Vibrio vulnificus Type 6 Secretion System 1 Contains Anti-Bacterial Properties. PLoS One, 11(10). Abstract.  Author URL.  Full text.
Nandi T, Holden MTG, Didelot X, Mehershahi K, Boddey JA, Beacham I, Peak I, Harting J, Baybayan P, Guo Y, et al (2015). Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles. Genome Res, 25(1), 129-141. Abstract.  Author URL.
Nandi T, Holden MTG, Didelot X, Mehershahi K, Boddey JA, Beacham I, Peak I, Harting J, Baybayan P, Guo Y, et al (2015). Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles. Genome Res, 25(4). Author URL.  Full text.
Nandi T, Holden MTG, Didelot X, Mehershahi K, Boddey JA, Beacham I, Peak I, Harting J, Baybayan P, Guo Y, et al (2015). Errata: Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles (Genome Research (2015) 25 (129-141)). Genome Research, 25(4).
Aiken SS, Cooper JJ, Florance H, Robinson MT, Michell S (2015). Local Release of Antibiotics for Surgical Site Infection Management Using High-Purity Calcium Sulfate: an in Vitro Elution Study. SURGICAL INFECTIONS, 16(1), 54-61. Author URL.
Charlton TM, Kovacs-Simon A, Michell SL, Fairweather NF, Tate EW (2015). Quantitative Lipoproteomics in Clostridium difficile Reveals a Role for Lipoproteins in Sporulation. CHEMISTRY & BIOLOGY, 22(11), 1562-1573. Author URL.  Full text.
Peano C, Chiaramonte F, Motta S, Pietrelli A, Jaillon S, Rossi E, Consolandi C, Champion OL, Michell SL, Freddi L, et al (2014). Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis. PLoS One, 9(3). Abstract.  Author URL.  Full text.
Kovacs-Simon A, Leuzzi R, Kasendra M, Minton N, Titball RW, Michell SL (2014). Lipoprotein CD0873 is a novel adhesin of Clostridium difficile. J Infect Dis, 210(2), 274-284. Abstract.  Author URL.
Butt E, Foster JAH, Keedwell E, Bell JEA, Titball RW, Bhangu A, Michell SL, Sheridan R (2013). Derivation and validation of a simple, accurate and robust prediction rule for risk of mortality in patients with Clostridium difficile infection. BMC Infect Dis, 13 Abstract.  Author URL.  Full text.
He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, et al (2013). Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nature Genetics, 45(1), 109-113. Abstract.
Gourlay LJ, Peri C, Ferrer-Navarro M, Conchillo-Solé O, Gori A, Rinchai D, Thomas RJ, Champion OL, Michell SL, Kewcharoenwong C, et al (2013). Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chem Biol, 20(9), 1147-1156. Abstract.  Author URL.
Michell SL (2012). A better understanding of what makes some proteins "fat". J Bacteriol, 194(9), 2129-2130. Author URL.
He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, et al (2012). Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nature Genetics
Foster JAH, Butt JEC, Bell J, Goff A, Morgan C, Hancock J, Carmichael C, Keedwell EC, Michell SLI, Sheridan RP, et al (2012). IMPROVING CLINICAL MANAGEMENT IN CLOSTRIDIUM DIFFICILE: FAECAL CALPROTECTIN DOES NOT PREDICT SEVERITY, RECURRENCE OR MORTALITY. AGE AND AGEING, 41, 72-72. Author URL.
Thomas RM, Twine SM, Fulton KM, Tessier L, Kilmury SLN, Ding W, Harmer N, Michell SL, Oyston PCF, Titball RW, et al (2011). Glycosylation of DsbA in Francisella tularensis subsp. tularensis. J Bacteriol, 193(19), 5498-5509. Abstract.  Author URL.
Kovacs-Simon A, Titball RW, Michell SL (2011). Lipoproteins of bacterial pathogens. Infect Immun, 79(2), 548-561. Abstract.  Author URL.
Wand ME, Müller CM, Titball RW, Michell SL (2011). Macrophage and Galleria mellonella infection models reflect the virulence of naturally occurring isolates of B. pseudomallei, B. thailandensis and B. oklahomensis. BMC Microbiol, 11(1). Abstract.  Author URL.  Full text.
Wang W, Hale C, Goulding D, Haslam SM, Tissot B, Lindsay C, Michell S, Titball R, Yu J, Toribio AL, et al (2011). Mannosidase 2, alpha 1 deficiency is associated with ricin resistance in embryonic stem (ES) cells. PLoS One, 6(8). Abstract.  Author URL.  Full text.
Vanaporn M, Wand M, Michell SL, Sarkar-Tyson M, Ireland P, Goldman S, Kewcharoenwong C, Rinchai D, Lertmemongkolchai G, Titball RW, et al (2011). Superoxide dismutase C is required for intracellular survival and virulence of Burkholderia pseudomallei. Microbiology, 157(Pt 8), 2392-2400. Abstract.  Author URL.
Michell SL, Dean RE, Eyles JE, Hartley MG, Waters E, Prior JL, Titball RW, Oyston PCF (2010). Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia. J Med Microbiol, 59(Pt 11), 1275-1284. Abstract.  Author URL.
Forslund A-L, Salomonsson EN, Golovliov I, Kuoppa K, Michell S, Titball R, Oyston P, Noppa L, Sjöstedt A, Forsberg A, et al (2010). The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis. BMC Microbiol, 10 Abstract.  Author URL.  Full text.
Champion MD, Zeng Q, Nix EB, Nano FE, Keim P, Kodira CD, Borowsky M, Young S, Koehrsen M, Engels R, et al (2009). Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies. PLoS Pathog, 5(5). Abstract.  Author URL.  Full text.
Richards MI, Michell SL, Oyston PCF (2008). An intracellularly inducible gene involved in virulence and polyphosphate production in Francisella. J Med Microbiol, 57(Pt 10), 1183-1192. Abstract.  Author URL.
Michell, S.L. Diaper, H. Wikstrom, P. Titball, RW (2007). A 55 kDa hypothetical membrane protein is an iron-regulated virulence factor of Francisella tularensis subspecies novicida U112. Journal of Medical Microbiology, 56, 1268-1276.
Isherwood, K.E. Michell, S.L. Diaper, H. Titball, RW (2007). A Francisella tularensis subspecies novicida purF mutant, but not a purA mutant, induces protective immunity to tularemia in mice. Vaccine, 25, 2011-2018.
sm202, Grice ID, Griffin K, Hitchen PG (2007). The immunologically distinct O-antigens from Francisella tularensis subspecies tuarensis and Francisella novicida are both virulence determinants and protective antigens. Infection and Immunity, 75(1), 371-378.
sm202, Bystrom A, Forslund AL, Johansson A (2006). Direct repeat-mediated deletion of a type IV pilin gene results in major virulence attenuation of Francisella tularensis. Molecular Microbiology, 59(6), 1818-1830.
RT101, Andersson SGE, Chain P, Chu MC (2005). The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nature Genetics, 37(2), 153-159.
Michell SL, Whelan AO, Wheeler PR, Panico M, Easton RL, Etienne AT, Haslam SM, Dell A, Morris HR, Reason AJ, et al (2003). The MPB83 antigen from Mycobacterium bovis contains O-linked mannose and (1->3)-mannibiose moieties. Journal of Biological Chemistry, 278(18), 16423-16432.
Wooff EE, Michell SL, Gordon SV, Chambers MA, Bardarov A, Jacobs Jr WR, Hewinson RG, Wheeler PR (2002). Functional genomics reveals the sole sulphate transporter of the mycobacterium tuberculosis complex and its relevance to the acquisition of sulphate in vivo. Molecular Microbiology, 43(3), 653-663.
Wiker HG, Michell SL, Hewinson RG, Spierings E, Nagai S, Harboe M (1999). Cloning, expression and significance of MPT53 for identification of secreted proteins of Mycobacterium tuberculosis. Microbial Pathogenesis, 26(4), 207-219. Abstract.
Hewinson RG, Michell SL, Russell WP, McAdam RA, Jacobs WR (1996). Molecular characterization of MPT83: a seroreactive antigen of Mycobacterium tuberculosis with homology to MPT70. Scand J Immunol, 43(5), 490-499. Abstract.  Author URL.

Chapters

Michell S, Griffin, K.F. Titball, R.W. (2006). Tularemia Pathogenesis and Immunity. In Friedman H, Anderson B (Eds.) Microbial Infection and Bioterrorism, Kluwer Academic Publishers, 121-138.

Publications by year


2016

Church SR, Lux T, Baker-Austin C, Buddington SP, Michell SL (2016). Vibrio vulnificus Type 6 Secretion System 1 Contains Anti-Bacterial Properties. PLoS One, 11(10). Abstract.  Author URL.  Full text.

2015

Nandi T, Holden MTG, Didelot X, Mehershahi K, Boddey JA, Beacham I, Peak I, Harting J, Baybayan P, Guo Y, et al (2015). Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles. Genome Res, 25(1), 129-141. Abstract.  Author URL.
Nandi T, Holden MTG, Didelot X, Mehershahi K, Boddey JA, Beacham I, Peak I, Harting J, Baybayan P, Guo Y, et al (2015). Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles. Genome Res, 25(4). Author URL.  Full text.
Nandi T, Holden MTG, Didelot X, Mehershahi K, Boddey JA, Beacham I, Peak I, Harting J, Baybayan P, Guo Y, et al (2015). Errata: Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles (Genome Research (2015) 25 (129-141)). Genome Research, 25(4).
Aiken SS, Cooper JJ, Florance H, Robinson MT, Michell S (2015). Local Release of Antibiotics for Surgical Site Infection Management Using High-Purity Calcium Sulfate: an in Vitro Elution Study. SURGICAL INFECTIONS, 16(1), 54-61. Author URL.
Charlton TM, Kovacs-Simon A, Michell SL, Fairweather NF, Tate EW (2015). Quantitative Lipoproteomics in Clostridium difficile Reveals a Role for Lipoproteins in Sporulation. CHEMISTRY & BIOLOGY, 22(11), 1562-1573. Author URL.  Full text.

2014

Peano C, Chiaramonte F, Motta S, Pietrelli A, Jaillon S, Rossi E, Consolandi C, Champion OL, Michell SL, Freddi L, et al (2014). Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis. PLoS One, 9(3). Abstract.  Author URL.  Full text.
Kovacs-Simon A, Leuzzi R, Kasendra M, Minton N, Titball RW, Michell SL (2014). Lipoprotein CD0873 is a novel adhesin of Clostridium difficile. J Infect Dis, 210(2), 274-284. Abstract.  Author URL.

2013

Butt E, Foster JAH, Keedwell E, Bell JEA, Titball RW, Bhangu A, Michell SL, Sheridan R (2013). Derivation and validation of a simple, accurate and robust prediction rule for risk of mortality in patients with Clostridium difficile infection. BMC Infect Dis, 13 Abstract.  Author URL.  Full text.
He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, et al (2013). Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nature Genetics, 45(1), 109-113. Abstract.
Gourlay LJ, Peri C, Ferrer-Navarro M, Conchillo-Solé O, Gori A, Rinchai D, Thomas RJ, Champion OL, Michell SL, Kewcharoenwong C, et al (2013). Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chem Biol, 20(9), 1147-1156. Abstract.  Author URL.

2012

Michell SL (2012). A better understanding of what makes some proteins "fat". J Bacteriol, 194(9), 2129-2130. Author URL.
He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, et al (2012). Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nature Genetics
Foster JAH, Butt JEC, Bell J, Goff A, Morgan C, Hancock J, Carmichael C, Keedwell EC, Michell SLI, Sheridan RP, et al (2012). IMPROVING CLINICAL MANAGEMENT IN CLOSTRIDIUM DIFFICILE: FAECAL CALPROTECTIN DOES NOT PREDICT SEVERITY, RECURRENCE OR MORTALITY. AGE AND AGEING, 41, 72-72. Author URL.

2011

Thomas RM, Twine SM, Fulton KM, Tessier L, Kilmury SLN, Ding W, Harmer N, Michell SL, Oyston PCF, Titball RW, et al (2011). Glycosylation of DsbA in Francisella tularensis subsp. tularensis. J Bacteriol, 193(19), 5498-5509. Abstract.  Author URL.
Kovacs-Simon A, Titball RW, Michell SL (2011). Lipoproteins of bacterial pathogens. Infect Immun, 79(2), 548-561. Abstract.  Author URL.
Wand ME, Müller CM, Titball RW, Michell SL (2011). Macrophage and Galleria mellonella infection models reflect the virulence of naturally occurring isolates of B. pseudomallei, B. thailandensis and B. oklahomensis. BMC Microbiol, 11(1). Abstract.  Author URL.  Full text.
Wang W, Hale C, Goulding D, Haslam SM, Tissot B, Lindsay C, Michell S, Titball R, Yu J, Toribio AL, et al (2011). Mannosidase 2, alpha 1 deficiency is associated with ricin resistance in embryonic stem (ES) cells. PLoS One, 6(8). Abstract.  Author URL.  Full text.
Vanaporn M, Wand M, Michell SL, Sarkar-Tyson M, Ireland P, Goldman S, Kewcharoenwong C, Rinchai D, Lertmemongkolchai G, Titball RW, et al (2011). Superoxide dismutase C is required for intracellular survival and virulence of Burkholderia pseudomallei. Microbiology, 157(Pt 8), 2392-2400. Abstract.  Author URL.

2010

Michell SL, Dean RE, Eyles JE, Hartley MG, Waters E, Prior JL, Titball RW, Oyston PCF (2010). Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia. J Med Microbiol, 59(Pt 11), 1275-1284. Abstract.  Author URL.
Forslund A-L, Salomonsson EN, Golovliov I, Kuoppa K, Michell S, Titball R, Oyston P, Noppa L, Sjöstedt A, Forsberg A, et al (2010). The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis. BMC Microbiol, 10 Abstract.  Author URL.  Full text.

2009

Champion MD, Zeng Q, Nix EB, Nano FE, Keim P, Kodira CD, Borowsky M, Young S, Koehrsen M, Engels R, et al (2009). Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies. PLoS Pathog, 5(5). Abstract.  Author URL.  Full text.

2008

Richards MI, Michell SL, Oyston PCF (2008). An intracellularly inducible gene involved in virulence and polyphosphate production in Francisella. J Med Microbiol, 57(Pt 10), 1183-1192. Abstract.  Author URL.

2007

Michell, S.L. Diaper, H. Wikstrom, P. Titball, RW (2007). A 55 kDa hypothetical membrane protein is an iron-regulated virulence factor of Francisella tularensis subspecies novicida U112. Journal of Medical Microbiology, 56, 1268-1276.
Isherwood, K.E. Michell, S.L. Diaper, H. Titball, RW (2007). A Francisella tularensis subspecies novicida purF mutant, but not a purA mutant, induces protective immunity to tularemia in mice. Vaccine, 25, 2011-2018.
sm202, Grice ID, Griffin K, Hitchen PG (2007). The immunologically distinct O-antigens from Francisella tularensis subspecies tuarensis and Francisella novicida are both virulence determinants and protective antigens. Infection and Immunity, 75(1), 371-378.

2006

sm202, Bystrom A, Forslund AL, Johansson A (2006). Direct repeat-mediated deletion of a type IV pilin gene results in major virulence attenuation of Francisella tularensis. Molecular Microbiology, 59(6), 1818-1830.
Michell S, Griffin, K.F. Titball, R.W. (2006). Tularemia Pathogenesis and Immunity. In Friedman H, Anderson B (Eds.) Microbial Infection and Bioterrorism, Kluwer Academic Publishers, 121-138.

2005

RT101, Andersson SGE, Chain P, Chu MC (2005). The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nature Genetics, 37(2), 153-159.

2003

Michell SL, Whelan AO, Wheeler PR, Panico M, Easton RL, Etienne AT, Haslam SM, Dell A, Morris HR, Reason AJ, et al (2003). The MPB83 antigen from Mycobacterium bovis contains O-linked mannose and (1->3)-mannibiose moieties. Journal of Biological Chemistry, 278(18), 16423-16432.

2002

Wooff EE, Michell SL, Gordon SV, Chambers MA, Bardarov A, Jacobs Jr WR, Hewinson RG, Wheeler PR (2002). Functional genomics reveals the sole sulphate transporter of the mycobacterium tuberculosis complex and its relevance to the acquisition of sulphate in vivo. Molecular Microbiology, 43(3), 653-663.

1999

Wiker HG, Michell SL, Hewinson RG, Spierings E, Nagai S, Harboe M (1999). Cloning, expression and significance of MPT53 for identification of secreted proteins of Mycobacterium tuberculosis. Microbial Pathogenesis, 26(4), 207-219. Abstract.

1996

Hewinson RG, Michell SL, Russell WP, McAdam RA, Jacobs WR (1996). Molecular characterization of MPT83: a seroreactive antigen of Mycobacterium tuberculosis with homology to MPT70. Scand J Immunol, 43(5), 490-499. Abstract.  Author URL.

stephen_michell Details from cache as at 2018-12-11 18:35:38

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External Engagment and Impact

Committee/panel activities

Member of Prokaryotic Division, Microbiology Society. 2014- 2018

Advisor to DTI on the export of Biological Agents


Editorial responsibilities

Editor of Journal of Medical Microbiology 2014 - current 

Member of the Editorial board of Frontiers in Microbial Physiology and Metabolism 


Invited lectures

2016: XIII Congress of the Federazione Italiana Scienze della Vita, Rome

January 2012: Seminar at the University of Milan 20th Jan 2012

March 2004:  Laboratoire de Microbiologie et Genetique Moleculaires du CNRS, Universite Paul Sabatier, Toulouse Scientific Seminar Program

May 2001: Albert Einstein College of Medicine, Yeshiva University New York, Department of Microbiology and Immunology Scientific Seminar Program


Media Coverage

Scientists launch a new study into C-diff treatment (Western Morning News)

C. diff test to predict patients most at risk (BBC)

Life saving test (BBC Spotlight video)

Exeter University and Newton Abbot College join the fight against bacterial resistance (Exeter Express and Echo)

Scientists launch a new study into C-diff treatment (This is Devon)


Workshops/Conferences organised

 Member of the organising committee of the  South West and South Wales Microbiology Forum 2009

Teaching

I contribute  to the 2nd year modules, Molecular Biology of the Gene (BIO2089), Molecular Microbiology (BIO2094) and the 3rd year module, Microbial Effectors of disease (BIO3080). I am co-ordinator of the first year module, Microbiology (BIO1337).

Modules

2018/19


Supervision / Group

Postdoctoral researchers

  • Julie Fletcher
  • Andrea Kovacs-Simon

Postgraduate researchers

  • Cameron Hubert

Alumni

  • Dr Emma Butt
  • Dr Selina Church
  • Edward Farries
  • Dr Matthew Wand

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