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Dr Stephen Aves

Dr Stephen Aves

Associate Professor of Molecular Biology

 5167

 +44 (0) 1392 725167

 Geoffrey Pope M03

 

Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK

Dr Steve Aves in the lab

Dr Steve Aves in the lab

Overview

I am a molecular biologist studying yeast and other micro-organisms.  I have research interests in DNA replication, the cell division cycle and genome organisation, molecular and synthetic biology approaches applied to biofuel production in micro-organisms, and microbial consortia. I teach molecular genetics.

I am a member of the Fungal Biology and the Cell & Molecular Biology and Development research groups. 

Qualifications

2012 Senior Fellow of The Higher Education Academy
2012 ASPIRE Senior Fellowship
2002 SEDA Full Accreditation
1984 PhD Molecular Biology, University of Bristol
1979 BA (Hons) Biology, University of York

Career

2006-present Associate Professor in Molecular Biology, Biosciences, University of Exeter
2004-2006 Senior Lecturer, School of Biosciences, University of Exeter
1986-2004 Lecturer, School of Biological Sciences, University of Exeter
Summer 1987 Danish Research Academy Visiting Professor, Institute of Genetics, University of Copenhagen
1984-1986 Research Fellow, University of Sussex & Imperial Cancer Research Fund Laboratories, London

Research group links

Dr Steve Aves in the lab

Dr Steve Aves in the lab

Research

Research interests

DNA replication and genome organisation.  Before a cell can divide it must first copy its genome, and even a small mistake in DNA replication can lead to a problem such as the production of a cell that can cause cancer. We investigate the DNA replication complex using molecular and genetic strategies, with cells of the fission yeast Schizosaccharomyces pombe as a model. Our research has focused on the essential Mcm10 initiation protein, its interactions with other DNA replication components, and the evolution of DNA replication components in eukaryotes.

Microbial biotechnology.  We are using molecular genetic, bioinformatic and synthetic biology methods to study production of biofuels and other products in micro-organisms.  Our particular interests are in oleaginous yeasts, and developing molecular genetic tools for researching, exploitation and metabolic engineering of these fungi.

Microbial consortia.  Micro-organisms frequently live in multi-species consortia, but the composition and interactions of these are often poorly understood. In collaboration with others, we use metagenomics and bioinformatic analysis to investigate microbial consortia associated with hydrocarbon generation and acid mine drainage.

Research networks

1997-2002 European Union Schizosaccharomyces genome sequencing consortium
2001-present Schizosaccharomyces pombe International Gene Naming Committee

Publications

Key publications | Publications by category | Publications by year

Key publications


Brown SR, Staff M, Lee R, Love J, Parker DA, Aves SJ, Howard TP (2018). Design of Experiments Methodology to Build a Multifactorial Statistical Model Describing the Metabolic Interactions of Alcohol Dehydrogenase Isozymes in the Ethanol Biosynthetic Pathway of the Yeast Saccharomyces cerevisiae. ACS Synth Biol, 7(7), 1676-1684. Abstract.  Author URL.  Full text.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga. Botryococcus braunii. MicrobiologyOpen, 6(4), e00482-e00482. Full text.
Johns AMB, Love J, Aves SJ (2016). Four Inducible Promoters for Controlled Gene Expression in the Oleaginous Yeast Rhodotorula toruloides. Front Microbiol, 7 Abstract.  Author URL.  Full text.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.
Curtis BA, Tanifuji G, Burki F, Gruber A, Irimia M, Maruyama S, Arias MC, Ball SG, Gile GH, Hirakawa Y, et al (2012). Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature, 492(7427), 59-65. Abstract.  Author URL.
Taylor M, Moore K, Murray J, Aves SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10(11), 1154-1163. Full text.

Publications by category


Journal articles

Brown SR, Staff M, Lee R, Love J, Parker DA, Aves SJ, Howard TP (2018). Design of Experiments Methodology to Build a Multifactorial Statistical Model Describing the Metabolic Interactions of Alcohol Dehydrogenase Isozymes in the Ethanol Biosynthetic Pathway of the Yeast Saccharomyces cerevisiae. ACS Synth Biol, 7(7), 1676-1684. Abstract.  Author URL.  Full text.
Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2. Full text.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga. Botryococcus braunii. MicrobiologyOpen, 6(4), e00482-e00482. Full text.
Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.  Full text.
Johns AMB, Love J, Aves SJ (2016). Four Inducible Promoters for Controlled Gene Expression in the Oleaginous Yeast Rhodotorula toruloides. Front Microbiol, 7 Abstract.  Author URL.  Full text.
Milne SW, Cheetham J, Lloyd D, Shaw S, Moore K, Paszkiewicz KH, Aves SJ, Bates S (2014). Role of Candida albicans Tem1 in mitotic exit and cytokinesis. Fungal Genet Biol, 69, 84-95. Abstract.  Author URL.  Full text.
Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.
Curtis BA, Tanifuji G, Burki F, Gruber A, Irimia M, Maruyama S, Arias MC, Ball SG, Gile GH, Hirakawa Y, et al (2012). Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature, 492(7427), 59-65. Abstract.  Author URL.
King NC, Aves SJ (2012). Effect of A-level subject choice and entry tariff on final degree and level 1 performance in biosciences. Bioscience Education, 19 Abstract.
Aves SJ, Liu Y, Richards TA (2012). Evolutionary diversification of eukaryotic DNA replication machinery. Subcell Biochem, 62, 19-35. Abstract.  Author URL.
Milne SW, Cheetham J, Lloyd D, Aves S, Bates S (2011). Cassettes for PCR-mediated gene tagging in Candida albicans utilizing nourseothricin resistance. Yeast, 28(12), 833-841. Abstract.  Author URL.  Full text.
Bryant JA, Aves SJ (2011). Initiation of DNA replication: functional and evolutionary aspects. Ann Bot, 107(7), 1119-1126. Abstract.  Author URL.
Taylor M, Moore K, Murray J, Ayes SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA REPAIR, 10(11), 1154-1163. Author URL.
Taylor M, Moore K, Murray J, Aves SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10(11), 1154-1163. Full text.
Saunders DGO, Aves SJ, Talbot NJ (2010). Cell cycle-mediated regulation of plant infection by the rice blast fungus. Plant Cell, 22(2), 497-507. Abstract.  Author URL.  Full text.
Liu Y, Richards TA, Aves SJ (2009). Ancient diversification of eukaryotic MCM DNA replication proteins. BMC Evol Biol, 9 Abstract.  Full text.
Aves SJ (2009). DNA replication initiation. Methods Mol Biol, 521, 3-17. Abstract.  Author URL.
Patch A-M, Aves SJ (2007). Fingerprinting fission yeast: polymorphic markers for molecular genetic analysis of Schizosaccharomyces pombe strains. Microbiology, 153(Pt 3), 887-897. Abstract.  Author URL.
Boby T, Patch A-M, Aves SJ (2005). TRbase: a database relating tandem repeats to disease genes for the human genome. Bioinformatics, 21(6), 811-816. Abstract.  Author URL.
Gregan J, Lindner K, Brimage L, Franklin R, Namdar M, Hart EA, Aves SJ, Kearsey SE (2003). Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding. Mol Biol Cell, 14(9), 3876-3887. Abstract.  Author URL.  Full text.
Dambrauskas G, Aves SJ, Bryant JA, Francis D, Rogers HJ (2003). Genes encoding two essential DNA replication activation proteins, Cdc6 and Mcm3, exhibit very different patterns of expression in the tobacco BY-2 cell cycle. J Exp Bot, 54(383), 699-706. Abstract.  Author URL.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2003). The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002). NATURE, 421(6918), 94-94. Author URL.
Hart EA, Bryant JA, Moore K, Aves SJ (2002). Fission yeast Cdc23 interactions with DNA replication initiation proteins. Curr Genet, 41(5), 342-348. Abstract.  Author URL.
Wood V, Gwilliam R, Rajandream M-A, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2002). The genome sequence of Schizosaccharomyces pombe. Nature, 415(6874), 871-880. Abstract.  Author URL.
Aves SJ, Hunt C, Xiang Z, Lyne MH, Wood V, Rajandream M-A, Skelton J, Churcher CM, Warren T, Harris D, et al (2002). The mei3 region of the Schizosaccharomyces pombe genome. Yeast, 19(6), 521-527. Abstract.  Author URL.
Bryant JA, Moore K, Aves SJ (2001). Origins and complexes: the initiation of DNA replication. J Exp Bot, 52(355), 193-202. Abstract.  Author URL.
Hunt C, Moore K, Xiang Z, Hurst SM, McDougall RC, Rajandream MA, Barrell BG, Gwilliam R, Wood V, Lyne MH, et al (2001). Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes. Yeast, 18(4), 355-361. Abstract.  Author URL.
Xiang Z, Moore K, Wood V, Rajandream MA, Barrell BG, Skelton J, Churcher CM, Lyne MH, Devlin K, Gwilliam R, et al (2000). Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5. Yeast, 16(15), 1405-1411. Abstract.  Author URL.
Brown JA, Paley RK, Amer S, Aves SJ (2000). Evidence for an intrarenal renin-angiotensin system in the rainbow trout, Oncorhynchus mykiss. Am J Physiol Regul Integr Comp Physiol, 278(6), R1685-R1691. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). The mating-type region of Schizosaccharomyces pombe h(-S) 972: sequencing and analysis of 69 kb including the expressed mat1 locus. Yeast, 16(11), 1061-1067. Abstract.  Author URL.
Xiang Z, Lyne MH, Wood V, Rajandream MA, Barrell BG, Aves SJ (1999). DNA sequencing and analysis of a 67.4 kb region from the right arm of Schizosaccharomyces pombe chromosome II reveals 28 open reading frames including the genes his5, pol5, ppa2, rip1, rpb8 and skb1. Yeast, 15(10A), 893-901. Abstract.  Author URL.
Smerdon GR, Walton EF, Aves SJ (1998). Stable production of human gastric lipase by chromosomal integration in the fission yeast Schizosaccharomyces pombe. Appl Microbiol Biotechnol, 49(1), 45-50. Abstract.  Author URL.
Aves SJ, Tongue N, Foster AJ, Hart EA (1998). The essential schizosaccharomyces pombe cdc23 DNA replication gene shares structural and functional homology with the Saccharomyces cerevisiae DNA43 (MCM10) gene. Curr Genet, 34(3), 164-171. Abstract.  Author URL.
Aves SJ, Tongue N, Findlay KL, Rich WJ, West SP (1997). CTG trinucleotide repeat lengths in myotonic dystrophy alleles of patients with senile cataracts. Hum Mutat, 9(1), 95-96. Author URL.
Aves SJ, Hindley J, Phear GA, Tongue N (1995). A fission yeast gene mapping close to suc1 encodes a protein containing two bromodomains. Mol Gen Genet, 248(4), 491-498. Abstract.  Author URL.
Smerdon GR, Aves SJ, Walton EF (1995). Production of human gastric lipase in the fission yeast Schizosaccharomyces pombe. Gene, 165(2), 313-318. Abstract.  Author URL.
Carr AM, Dorrington SM, Hindley J, Phear GA, Aves SJ, Nurse P (1994). Analysis of a histone H2A variant from fission yeast: evidence for a role in chromosome stability. Mol Gen Genet, 245(5), 628-635. Abstract.  Author URL.
Hayles J, Aves S, Nurse P (1986). suc1 is an essential gene involved in both the cell cycle and growth in fission yeast. EMBO J, 5(12), 3373-3379. Abstract.  Author URL.  Full text.
Aves SJ, Durkacz BW, Carr A, Nurse P (1985). Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 'start' gene. EMBO J, 4(2), 457-463. Abstract.  Author URL.

Chapters

Brown S, Loh J, Aves SJ, Howard T (2018). Alkane Biosynthesis in Bacteria. In Stams A, Sousa D (Eds.) Biogenesis of Hydrocarbons, Handbook of Hydrocarbon and Lipid Microbiology, Springer. Abstract.  Full text.
Moore K, Aves SJ (2008). Mcml0 and DNA replication in fission yeast. In  (Ed) , 45-69.  Author URL.

Conferences

Brown S, Howard TP, Aves SJ (2015). An experimental design approach for engineering carbon metabolism in the yeast Saccharomyces cerevisiae.  Author URL.
Brown JA, Pope SK, Amer S, Cobb CS, Williamson R, Parkyn G, Aves SJ (1997). Angiotensin receptors in teleost fish glomeruli.  Author URL.
Parkyn G, Aves SJ, Brown JA (1997). Cloning and characterisation of the rainbow trout angiotensin receptor.  Author URL.
AVES SJ, BRYANT JA (1993). THE MOLECULAR-GENETICS AND BIOCHEMISTRY OF DNA-REPLICATION.  Author URL.

Publications by year


2018

Brown S, Loh J, Aves SJ, Howard T (2018). Alkane Biosynthesis in Bacteria. In Stams A, Sousa D (Eds.) Biogenesis of Hydrocarbons, Handbook of Hydrocarbon and Lipid Microbiology, Springer. Abstract.  Full text.
Brown SR, Staff M, Lee R, Love J, Parker DA, Aves SJ, Howard TP (2018). Design of Experiments Methodology to Build a Multifactorial Statistical Model Describing the Metabolic Interactions of Alcohol Dehydrogenase Isozymes in the Ethanol Biosynthetic Pathway of the Yeast Saccharomyces cerevisiae. ACS Synth Biol, 7(7), 1676-1684. Abstract.  Author URL.  Full text.

2017

Sambles C, Middelhaufe S, Soanes D, Kolak D, Lux T, Moore K, Matoušková P, Parker D, Lee R, Love J, et al (2017). Genome sequence of the oleaginous yeast Rhodotorula toruloides strain CGMCC 2.1609. Genomics Data, 13, 1-2. Full text.
Sambles C, Moore K, Lux TM, Jones K, Littlejohn GR, Gouveia JD, Aves SJ, Studholme DJ, Lee R, Love J, et al (2017). Metagenomic analysis of the complex microbial consortium associated with cultures of the oil-rich alga. Botryococcus braunii. MicrobiologyOpen, 6(4), e00482-e00482. Full text.

2016

Jones KJ, Moore K, Sambles C, Love J, Studholme DJ, Aves SJ (2016). Draft Genome Sequences of Achromobacter piechaudii GCS2, Agrobacterium sp. Strain SUL3, Microbacterium sp. Strain GCS4, Shinella sp. Strain GWS1, and Shinella sp. Strain SUS2 Isolated from Consortium with the Hydrocarbon-Producing Alga Botryococcus braunii. Genome Announc, 4(1). Abstract.  Author URL.  Full text.
Johns AMB, Love J, Aves SJ (2016). Four Inducible Promoters for Controlled Gene Expression in the Oleaginous Yeast Rhodotorula toruloides. Front Microbiol, 7 Abstract.  Author URL.  Full text.

2015

Brown S, Howard TP, Aves SJ (2015). An experimental design approach for engineering carbon metabolism in the yeast Saccharomyces cerevisiae.  Author URL.

2014

Milne SW, Cheetham J, Lloyd D, Shaw S, Moore K, Paszkiewicz KH, Aves SJ, Bates S (2014). Role of Candida albicans Tem1 in mitotic exit and cytokinesis. Fungal Genet Biol, 69, 84-95. Abstract.  Author URL.  Full text.

2013

Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, et al (2013). Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli. Proc Natl Acad Sci USA, 110, 7636-7641. Abstract.  Author URL.  Full text.

2012

Curtis BA, Tanifuji G, Burki F, Gruber A, Irimia M, Maruyama S, Arias MC, Ball SG, Gile GH, Hirakawa Y, et al (2012). Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature, 492(7427), 59-65. Abstract.  Author URL.
King NC, Aves SJ (2012). Effect of A-level subject choice and entry tariff on final degree and level 1 performance in biosciences. Bioscience Education, 19 Abstract.
Aves SJ, Liu Y, Richards TA (2012). Evolutionary diversification of eukaryotic DNA replication machinery. Subcell Biochem, 62, 19-35. Abstract.  Author URL.

2011

Milne SW, Cheetham J, Lloyd D, Aves S, Bates S (2011). Cassettes for PCR-mediated gene tagging in Candida albicans utilizing nourseothricin resistance. Yeast, 28(12), 833-841. Abstract.  Author URL.  Full text.
Bryant JA, Aves SJ (2011). Initiation of DNA replication: functional and evolutionary aspects. Ann Bot, 107(7), 1119-1126. Abstract.  Author URL.
Taylor M, Moore K, Murray J, Ayes SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA REPAIR, 10(11), 1154-1163. Author URL.
Taylor M, Moore K, Murray J, Aves SJ, Price C (2011). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10(11), 1154-1163. Full text.

2010

Saunders DGO, Aves SJ, Talbot NJ (2010). Cell cycle-mediated regulation of plant infection by the rice blast fungus. Plant Cell, 22(2), 497-507. Abstract.  Author URL.  Full text.

2009

Liu Y, Richards TA, Aves SJ (2009). Ancient diversification of eukaryotic MCM DNA replication proteins. BMC Evol Biol, 9 Abstract.  Full text.
Aves SJ (2009). DNA replication initiation. Methods Mol Biol, 521, 3-17. Abstract.  Author URL.

2008

Moore K, Aves SJ (2008). Mcml0 and DNA replication in fission yeast. In  (Ed) , 45-69.  Author URL.

2007

Patch A-M, Aves SJ (2007). Fingerprinting fission yeast: polymorphic markers for molecular genetic analysis of Schizosaccharomyces pombe strains. Microbiology, 153(Pt 3), 887-897. Abstract.  Author URL.

2005

Boby T, Patch A-M, Aves SJ (2005). TRbase: a database relating tandem repeats to disease genes for the human genome. Bioinformatics, 21(6), 811-816. Abstract.  Author URL.

2003

Gregan J, Lindner K, Brimage L, Franklin R, Namdar M, Hart EA, Aves SJ, Kearsey SE (2003). Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding. Mol Biol Cell, 14(9), 3876-3887. Abstract.  Author URL.  Full text.
Dambrauskas G, Aves SJ, Bryant JA, Francis D, Rogers HJ (2003). Genes encoding two essential DNA replication activation proteins, Cdc6 and Mcm3, exhibit very different patterns of expression in the tobacco BY-2 cell cycle. J Exp Bot, 54(383), 699-706. Abstract.  Author URL.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2003). The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002). NATURE, 421(6918), 94-94. Author URL.

2002

Hart EA, Bryant JA, Moore K, Aves SJ (2002). Fission yeast Cdc23 interactions with DNA replication initiation proteins. Curr Genet, 41(5), 342-348. Abstract.  Author URL.
Wood V, Gwilliam R, Rajandream M-A, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, et al (2002). The genome sequence of Schizosaccharomyces pombe. Nature, 415(6874), 871-880. Abstract.  Author URL.
Aves SJ, Hunt C, Xiang Z, Lyne MH, Wood V, Rajandream M-A, Skelton J, Churcher CM, Warren T, Harris D, et al (2002). The mei3 region of the Schizosaccharomyces pombe genome. Yeast, 19(6), 521-527. Abstract.  Author URL.

2001

Bryant JA, Moore K, Aves SJ (2001). Origins and complexes: the initiation of DNA replication. J Exp Bot, 52(355), 193-202. Abstract.  Author URL.
Hunt C, Moore K, Xiang Z, Hurst SM, McDougall RC, Rajandream MA, Barrell BG, Gwilliam R, Wood V, Lyne MH, et al (2001). Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes. Yeast, 18(4), 355-361. Abstract.  Author URL.

2000

Xiang Z, Moore K, Wood V, Rajandream MA, Barrell BG, Skelton J, Churcher CM, Lyne MH, Devlin K, Gwilliam R, et al (2000). Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5. Yeast, 16(15), 1405-1411. Abstract.  Author URL.
Brown JA, Paley RK, Amer S, Aves SJ (2000). Evidence for an intrarenal renin-angiotensin system in the rainbow trout, Oncorhynchus mykiss. Am J Physiol Regul Integr Comp Physiol, 278(6), R1685-R1691. Abstract.  Author URL.
Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, Aves SJ (2000). The mating-type region of Schizosaccharomyces pombe h(-S) 972: sequencing and analysis of 69 kb including the expressed mat1 locus. Yeast, 16(11), 1061-1067. Abstract.  Author URL.

1999

Xiang Z, Lyne MH, Wood V, Rajandream MA, Barrell BG, Aves SJ (1999). DNA sequencing and analysis of a 67.4 kb region from the right arm of Schizosaccharomyces pombe chromosome II reveals 28 open reading frames including the genes his5, pol5, ppa2, rip1, rpb8 and skb1. Yeast, 15(10A), 893-901. Abstract.  Author URL.

1998

Smerdon GR, Walton EF, Aves SJ (1998). Stable production of human gastric lipase by chromosomal integration in the fission yeast Schizosaccharomyces pombe. Appl Microbiol Biotechnol, 49(1), 45-50. Abstract.  Author URL.
Aves SJ, Tongue N, Foster AJ, Hart EA (1998). The essential schizosaccharomyces pombe cdc23 DNA replication gene shares structural and functional homology with the Saccharomyces cerevisiae DNA43 (MCM10) gene. Curr Genet, 34(3), 164-171. Abstract.  Author URL.

1997

Brown JA, Pope SK, Amer S, Cobb CS, Williamson R, Parkyn G, Aves SJ (1997). Angiotensin receptors in teleost fish glomeruli.  Author URL.
Aves SJ, Tongue N, Findlay KL, Rich WJ, West SP (1997). CTG trinucleotide repeat lengths in myotonic dystrophy alleles of patients with senile cataracts. Hum Mutat, 9(1), 95-96. Author URL.
Parkyn G, Aves SJ, Brown JA (1997). Cloning and characterisation of the rainbow trout angiotensin receptor.  Author URL.

1995

Aves SJ, Hindley J, Phear GA, Tongue N (1995). A fission yeast gene mapping close to suc1 encodes a protein containing two bromodomains. Mol Gen Genet, 248(4), 491-498. Abstract.  Author URL.
Smerdon GR, Aves SJ, Walton EF (1995). Production of human gastric lipase in the fission yeast Schizosaccharomyces pombe. Gene, 165(2), 313-318. Abstract.  Author URL.

1994

Carr AM, Dorrington SM, Hindley J, Phear GA, Aves SJ, Nurse P (1994). Analysis of a histone H2A variant from fission yeast: evidence for a role in chromosome stability. Mol Gen Genet, 245(5), 628-635. Abstract.  Author URL.

1993

AVES SJ, BRYANT JA (1993). THE MOLECULAR-GENETICS AND BIOCHEMISTRY OF DNA-REPLICATION.  Author URL.

1986

Hayles J, Aves S, Nurse P (1986). suc1 is an essential gene involved in both the cell cycle and growth in fission yeast. EMBO J, 5(12), 3373-3379. Abstract.  Author URL.  Full text.

1985

Aves SJ, Durkacz BW, Carr A, Nurse P (1985). Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 'start' gene. EMBO J, 4(2), 457-463. Abstract.  Author URL.

steve_aves Details from cache as at 2018-12-15 11:30:11

Refresh publications

External Engagment and Impact

Editorial responsibilities

2016-present Editorial Board, Scientific Reports


Invited lectures

2016 British Yeast Group Meeting, Swansea
2015 Society of Experimental Biology Annual Meeting, Prague


Other

2016 Programme Assessor for BSc/Integrated Masters programmes in Biological Sciences, Biochemistry, Biomedical Sciences, and Neuroscience, University of Cardiff


Workshops/Conferences organised

Scientific Committee, British Yeast Group Meeting 2014
Advisory Committee, British Mycological Society Annual Scientific Meeting 2011

Find out more as.exeter.ac.uk/aspire

Teaching

ASPIRE Mentor and panel member
ASPIRE Senior Fellow
Senior Fellow of the Higher Education Academy (HEA)
Full Accreditation from the Staff and Educational Development Association (SEDA)

Taught modules include:

  • BIO1334 Genetics
  • BIO3096 Biosciences Research Project

Modules

2018/19


Supervision / Group

Postgraduate researchers

  • George Kirke (Masters by Research)
  • Aaron Westlake (PhD)

Alumni

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