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Professor Richard ffrench-Constant

Professor Richard ffrench-Constant

Professor of Molecular Natural History

 01326 253729

 Daphne du Maurier -

 

Daphne du Maurier Building, University of Exeter,  Penryn Campus, Penryn, Cornwall, TR10 9FE, UK

Overview

I am currently engaged in work that spans three very different aspects of current biology: insecticide resistance, insect mimicry, and bacterial virulence (both to insects and to man). I use state-of-the art molecular techniques, such as cloning, BAC finger-printing, and EST sequencing, to facilitate advances in each of these important fields. My study organisms include Drosophila, several butterfly species, and the bacterial pathogen Photorhabdus. I am a member of the evolution research group.

My research has received substantial media coverage by a number of organizations and in a variety of formats. Mostly recently, our lab was featured in a short Nature video on the genetic control of butterfly mimicry.

Qualifications

1987: PhD at Imperial College, London University UK, in insecticide resistance
1983: MSc at the University of Southampton, UK, in entomology
1982: BSc (Hons) at the University of Exeter, UK, in biology

Career

2006-present Chair of Molecular Natural History, Biosciences, University of Exeter
2000-2006 Chair of Molecular Biology, Biology, and Biochemistry, University of Bath
1990-2000 Associate Professor of Entomology, Entomology, UW Madison, USA
1988-1990 Postdoctoral Research Fellow, Cornell University, USA
1987-1989 Postdoctoral Research Fellow, London School of Hygiene and Tropical Medicine

Research group links

Research

Research projects

Insecticide resistance: I am interested in the number of genes that control resistance, their nature and their frequency and fitness in natural populations. We work on the Resistance to dieldrin gene which encodes a GABA receptor and also on the metabolic resistance conferred by cytochrome P450s. Central questions are: How do resistance associated mutations have their effect? How many times do these mutations evolve? Do they carry any fitness cost?

Butterfly mimicry: I am also interested in the molecular nature of the genes that control mimicry in butterflies. We work on models of both Batesian and Mullerian mimicry. The Eastern Tiger Swallowtail of North America has melanic females that mimic the Pipevine Swallowtail. We study the molecular basis of pigment production and the nature of the switch gene that turns these yellow and black butterflies black.

We also work on Mullerian mimicry in Heliconius butterflies. Here we collaborate with Chris Jiggins (Cambridge) and Sean Humphray (Sanger) to clone the genes involved in colouration in H. melpomene, H. erato and H. numata. Central questions are: How many genes control colour pattern in different species? What are the genes that control colouration? Do different species use the same genes to achieve the same patterns?

Bacterial infection: We use bacterial that kill insects (Photorhabdus) to study the interaction between bacterial effectors and the insect immune system. We clone novel bacterial effectors from Photorhabdus and then use RNAi in the model host Manduca to study the insects immune response to bacterial infection. Central questions are: Do pathogens hide from the immune system or simply destroy it? What toxins do pathogens use to kill insects?

Research networks

  • Chris Jiggins, Zoology, Cambridge
  • Mathieu Joron, Zoology, Edinburgh
  • Sean Humphray, Wellcome Genome Campus, Hinxton
  • Rene Feyereisen INRA Sophia-Antipolis France

Research grants

  • 2007 BBSRC
    Heliconius mimicry
  • 2007 BBSRC
    Bacterial virulence
  • 2007 Leverhulme Trust
    Heliconius micmicry
  • 2005 BBSRC
    Mcf toxins
  • 2003 BBSRC
    Underwood award
  • 2002 BBSRC
    Photorhabdus genomics
  • 2002 Royal Society
    Merit Award
  • 2000 Wellcome/JIF
    Photorhabdus genomics
  • 2000 Leverhulme Trust
    Butterfly melanism
  • 2000 Royal Society
    Butterfly melanism
  • 2000 Syngenta
    Insecticide resistance

Publications

Key publications | Publications by category | Publications by year

Key publications


Rhodes M, Bennie J, Spalding A, ffrench-Constant R, Maclean I (In Press). Recent advances in the remote sensing of insects. Biological Reviews
Kim K-W, De-Kayne R, Gordon IJ, Omufwoko KS, Martins DJ, ffrench-Constant R, Martin SH (2021). Stepwise evolution of a butterfly supergene via duplication and inversion.
Traut W, Ahola V, Smith DAS, Gordon IJ, Ffrench-Constant RH (2018). Karyotypes versus Genomes: the Nymphalid Butterflies Melitaea cinxia, Danaus plexippus, and D. chrysippus. Cytogenetic and Genome Research, 153(1), 46-53. Abstract.
Schaum CE, Student Research Team, Ffrench-Constant R, Lowe C, Ólafsson JS, Padfield D, Yvon-Durocher G (2018). Temperature-driven selection on metabolic traits increases the strength of an algal-grazer interaction in naturally warmed streams. Glob Chang Biol, 24(4), 1793-1803. Abstract.  Author URL.
Smith DAS, Gordon IJ, Traut W, Herren J, Collins S, Martins DJ, Saitoti K, Ireri P, Ffrench-Constant R (2016). A neo-W chromosome in a tropical butterfly links colour pattern, male-killing, and speciation. Proceedings of the Royal Society B: Biological Sciences, 283(1835). Abstract.
Ffrench-Constant RH, Somers-Yeates R, Bennie J, Economou T, Hodgson D, Spalding A, McGregor PK (2016). Light pollution is associated with earlier tree budburst across the United Kingdom. Proceedings of the Royal Society of London. Series B

Publications by category


Journal articles

ffrench-Constant R (In Press). Hybrid effects in field populations of the African Monarch Danaus chrysippus. Biological Journal of the Linnean Society
Yvon-Durocher G, Padfield D, Buckling A, Lowe C, Ffrench-Constant R, Schaum E (In Press). Metabolic compensation constrains the temperature dependence of gross primary production. Ecology Letters
Rhodes M, Bennie J, Spalding A, ffrench-Constant R, Maclean I (In Press). Recent advances in the remote sensing of insects. Biological Reviews
Padfield D, Lowe C, Buckling A, Ffrench-Constant R, Schaum E, Jennings S, Shelley F, Ólafsson JS, Yvon-Durocher G (In Press). Thermal adaptation constrains the temperature dependence of ecosystem metabolism.  Abstract.
Kim K-W, De-Kayne R, Gordon IJ, Omufwoko KS, Martins DJ, Ffrench-Constant R, Martin SH (2022). Stepwise evolution of a butterfly supergene via duplication and inversion. Philos Trans R Soc Lond B Biol Sci, 377(1856). Abstract.  Author URL.
Singh KS, De-Kayne R, Omufwoko KS, Martins DJ, Bass C, ffrench-Constant R, Martin SH (2021). Genome assembly of Danaus chrysippus and comparison with the Monarch Danaus plexippus. G3: Genes, Genomes, Genetics, 12(3).
Singh KS, Cordeiro EMG, Troczka BJ, Pym A, Mackisack J, Mathers TC, Duarte A, Legeai F, Robin S, Bielza P, et al (2021). Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae. Commun Biol, 4(1). Abstract.  Author URL.
Singh KS, Hosken DJ, Wedell N, Ffrench-Constant R, Bass C, Baxter S, Paszkiewicz K, Sharma MD (2020). De Novo Genome Assembly of the Meadow Brown Butterfly, Maniola jurtina. G3 (Bethesda), 10(5), 1477-1484. Abstract.  Author URL.
McLeman A, Troczka BJ, Homem RA, Duarte A, Zimmer C, Garrood WT, Pym A, Beadle K, Reid RJ, Douris V, et al (2020). Fly-Tox: a panel of transgenic flies expressing pest and pollinator cytochrome P450s. Pesticide Biochemistry and Physiology, 169 Abstract.
ffrench-Constant R, Martin S, Bass C, Singh K, Traut W, Gordon I, Smith D, Martins D (2020). Whole-chromosome hitchhiking driven by a male-killing endosymbiont. PLoS Biology
Smith DAS, Traut W, Martin SH, Ireri P, Omufwoko KS, ffrench-Constant R, Gordon IJ (2019). Neo Sex Chromosomes, Colour Polymorphism and Male-Killing in the African Queen Butterfly, Danaus chrysippus (L.). Insects, 10(9), 291-291. Abstract.
Spalding A, Shanks K, Bennie J, Potter U, Ffrench-Constant R (2019). Optical Modelling and Phylogenetic Analysis Provide Clues to the Likely Function of Corneal Nipple Arrays in Butterflies and Moths. Insects, 10(9). Abstract.  Author URL.
Grant C, Jacobson R, Ilias A, Berger M, Vasakis E, Bielza P, Zimmer CT, Williamson MS, Ffrench-Constant RH, Vontas J, et al (2019). The evolution of multiple-insecticide resistance in UK populations of tomato leafminer, Tuta absoluta. Pest Manag Sci, 75(8), 2079-2085. Abstract.  Author URL.
Traut W, Ahola V, Smith DAS, Gordon IJ, Ffrench-Constant RH (2018). Karyotypes versus Genomes: the Nymphalid Butterflies Melitaea cinxia, Danaus plexippus, and D. chrysippus. Cytogenetic and Genome Research, 153(1), 46-53. Abstract.
Schaum CE, Student Research Team, Ffrench-Constant R, Lowe C, Ólafsson JS, Padfield D, Yvon-Durocher G (2018). Temperature-driven selection on metabolic traits increases the strength of an algal-grazer interaction in naturally warmed streams. Glob Chang Biol, 24(4), 1793-1803. Abstract.  Author URL.
ffrench-Constant RH, Bass C (2017). Does resistance really carry a fitness cost?. Current Opinion in Insect Science, 21, 39-46. Abstract.
Smith DAS, Gordon IJ, Traut W, Herren J, Collins S, Martins DJ, Saitoti K, Ireri P, Ffrench-Constant R (2016). A neo-W chromosome in a tropical butterfly links colour pattern, male-killing, and speciation. Proceedings of the Royal Society B: Biological Sciences, 283(1835). Abstract.
Ffrench-Constant RH (2016). Butterfly gene flow goes berserk. Genome Biology, 17(1).
Ffrench-Constant RH, Williamson MS, Davies TGE, Bass C (2016). Ion channels as insecticide targets. J Neurogenet, 30(3-4), 163-177. Abstract.  Author URL.
Ffrench-Constant RH, Somers-Yeates R, Bennie J, Economou T, Hodgson D, Spalding A, McGregor PK (2016). Light pollution is associated with earlier tree budburst across the United Kingdom. Proceedings of the Royal Society of London. Series B
Nadeau NJ, Pardo-Diaz C, Whibley A, Supple MA, Saenko SV, Wallbank RWR, Wu GC, Maroja L, Ferguson L, Hanly JJ, et al (2016). The gene cortex controls mimicry and crypsis in butterflies and moths. Nature, 534(7605), 106-110. Abstract.  Author URL.
Mulley G, Beeton ML, Wilkinson P, Vlisidou I, Ockendon-Powell N, Hapeshi A, Tobias NJ, Nollmann FI, Bode HB, van den Elsen J, et al (2015). From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity. PLOS ONE, 10(12), e0144937-e0144937.
Ffrench-Constant RH (2015). Insect Molecular Genetics: an Introduction to Principles and Applications. Third Edition. By Marjorie A. Hoy. Academic Press. Amsterdam (The Netherlands) and Boston (Massachusetts): Elsevier. $99.95. xxvii + 808 p.; ill.; index. ISBN: 978-0-12-415874-0. 2013. The Quarterly Review of Biology, 90(1), 98-98.
Pauchet Y, Wielsch N, Wilkinson PA, Sakaluk SK, Svatoš A, ffrench-Constant RH, Hunt J, Heckel DG (2015). What's in the Gift? Towards a Molecular Dissection of Nuptial Feeding in a Cricket. PLoS One, 10(10). Abstract.  Author URL.
Ffrench-Constant RH (2015). White butterflies as solar photovoltaic concentrators. Scientific Reports, 5
Proschak A, Zhou Q, Schöner T, Thanwisai A, Kresovic D, Dowling A, ffrench-Constant R, Proschak E, Bode HB (2014). Biosynthesis of the Insecticidal Xenocyloins in<i>Xenorhabdus bovienii</i>. ChemBioChem, 15(3), 369-372.
Timmermans MJTN, Baxter SW, Clark R, Heckel DG, Vogel H, Collins S, Papanicolaou A, Fukova I, Joron M, Thompson MJ, et al (2014). Comparative genomics of the mimicry switch in<i>Papilio dardanus</i>. Proceedings of the Royal Society B: Biological Sciences, 281(1787), 20140465-20140465. Abstract.
Ffrench-constant R, Valencia A, Eyun SI, Wang H, Pauchet Y, Benson AK (2014). Correction: Molecular evolution of glycoside hydrolase genes in the western corn rootworm (Diabrotica virgifera virgifera) (PLoS ONE (2014) 9, 4 (e94052) DOI: 10.1371/journal.pone.0094052). PLoS ONE, 9(7).
Ffrench-Constant RH (2014). GENOMICS of monarchs and migration. NATURE, 514(7522), 314-315. Author URL.
Kirsch R, Gramzow L, Theißen G, Siegfried BD, ffrench-Constant RH, Heckel DG, Pauchet Y (2014). Horizontal gene transfer and functional diversification of plant cell wall degrading polygalacturonases: Key events in the evolution of herbivory in beetles. Insect Biochemistry and Molecular Biology, 52, 33-50.
ffrench-Constant RH (2014). Insecticide resistance comes of age. Genome Biology, 15(2), 106-106.
Eyun SI, Wang H, Pauchet Y, Ffrench-Constant RH, Benson AK, Valencia-Jiménez A, Moriyama EN, Siegfried BD (2014). Molecular evolution of glycoside hydrolase genes in the western corn rootworm (Diabrotica virgifera virgifera). PLoS ONE, 9(4). Abstract.
Ffrench-Constant RH (2014). Of monarchs and migration. Nature, 514(7522), 314-315.
Ffrench-Constant RH, Dowling AJ (2014). Photorhabdus Toxins. INSECT MIDGUT AND INSECTICIDAL PROTEINS, 47, 343-388. Author URL.
ffrench-Constant RH (2014). Sex, butterflies and molecular biology: when pigmentation met mimicry. Pigment Cell & Melanoma Research, 27(4), 507-508.
Swevers L, Huvenne H, Menschaert G, Kontogiannatos D, Kourti A, Pauchet Y, ffrench-Constant R, Smagghe G (2013). Colorado potato beetle (Coleoptera) gut transcriptome analysis: expression of RNA interference-related genes. Insect Molecular Biology, 22(6), 668-684.
Chauhan R, Jones R, Wilkinson P, Pauchet Y, Ffrench-Constant RH (2013). Cytochrome P450-encoding genes from the Heliconius genome as candidates for cyanogenesis. Insect Molecular Biology, 22(5), 532-540. Abstract.
Chauhan R, Jones R, Wilkinson P, Pauchet Y, Ffrench-Constant RH (2013). Cytochrome P450-encoding genes from the Heliconius genome as candidates for cyanogenesis. Insect Mol Biol, 22(5), 532-540. Abstract.  Author URL.
Smee MR, Pauchet Y, Wilkinson P, Wee B, Singer MC, ffrench-Constant RH, Hodgson DJ, Mikheyev AS (2013). Microsatellites for the marsh fritillary butterfly: de novo transcriptome sequencing, and a comparison with amplified fragment length polymorphism (AFLP) markers. PLoS One, 8(1). Abstract.  Author URL.
Reimer D, Cowles KN, Proschak A, Nollmann FI, Dowling AJ, Kaiser M, Constant RF, Goodrich-Blair H, Bode HB (2013). Rhabdopeptides as insect-specific virulence factors from entomopathogenic bacteria. ChemBioChem
Somers-Yeates R, Hodgson D, McGregor PK, Spalding A, Ffrench-Constant RH (2013). Shedding light on moths: shorter wavelengths attract noctuids more than geometrids. Biol Lett, 9(4). Abstract.  Author URL.
ffrench-Constant RH (2013). The Molecular Genetics of Insecticide Resistance. Genetics, 194(4), 807-815. Abstract.
Ferreira PG, Patalano S, Chauhan R, Ffrench-Constant R, Gabaldón T, Guigó R, Sumner S (2013). Transcriptome analyses of primitively eusocial wasps reveal novel insights into the evolution of sociality and the origin of alternative phenotypes. Genome Biology, 14(2), R20-R20.
Jones RT, Poul YL, Whibley AC, Mérot C, ffrench-Constant RH, Joron M (2013). Wing Shape Variation Associated with Mimicry in Butterflies. Evolution, 67(8), 2323-2334. Abstract.
Dasmahapatra KK, Walters JR, Briscoe AD, Davey JW, Whibley A, Nadeau NJ, Zimin AV, Salazar C, Ferguson LC, Martin SH, et al (2012). Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. Nature, 487(7405), 94-98. Abstract.
Dasmahapatra KK, Walters JR, Briscoe AD, Davey JW, Whibley A, Nadeau NJ, Zimin AV, Hughes DST, Ferguson LC, Martin SH, et al (2012). Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. Nature
ffrench-Constant RH (2012). Butterfly wing colours and patterning by numbers. Heredity, 108(6), 592-593.
Jones RT, Salazar PA, ffrench-Constant RH, Jiggins CD, Joron M (2012). Evolution of a mimicry supergene from a multilocus architecture. Proc Biol Sci, 279(1727), 316-325. Abstract.  Author URL.
Nadeau NJ, Whibley A, Jones RT, Davey JW, Dasmahapatra KK, Baxter SW, Quail MA, Joron M, Ffrench-Constant RH, Blaxter ML, et al (2012). Genomic islands of divergence in hybridizing Heliconius butterflies identified by large-scale targeted sequencing. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 367(1587), 343-353. Author URL.
Grundmann F, Dill V, Dowling A, Thanwisai A, Bode E, Chantratita N, ffrench-Constant R, Bode HB (2012). Identification and isolation of insecticidal oxazoles from <i>Pseudomonas</i> spp. Beilstein Journal of Organic Chemistry, 8, 749-752. Abstract.
Karatolos N, Williamson MS, Denholm I, Gorman K, ffrench-Constant RH, Bass C (2012). Over-expression of a cytochrome P450 is associated with resistance to pyriproxyfen in the greenhouse whitefly trialeurodes vaporariorum. PLoS ONE, 7(2). Abstract.
Yang G, Hernandez-Rodriguez CS, Beeton ML, Wilkinson P, Ffrench-Constant RH, Waterfield NR (2012). Pdl1 is a Putative Lipase that Enhances Photorhabdus Toxin Complex Secretion. PLOS PATHOGENS, 8(5). Author URL.
Karatolos N, Williamson MS, Denholm I, Gorman K, Ffrench-Constant R, Nauen R (2012). Resistance to spiromesifen in Trialeurodes vaporariorum is associated with a single amino acid replacement in its target enzyme acetyl-coenzyme a carboxylase. Insect Molecular Biology, 21(3), 327-334. Abstract.
Nollmann FI, Dowling A, Kaiser M, Deckmann K, Grösch S, ffrench-Constant R, Bode HB (2012). Synthesis of szentiamide, a depsipeptide from entomopathogenic <i>Xenorhabdus szentirmaii</i> with activity against <i>Plasmodium falciparum</i>. Beilstein Journal of Organic Chemistry, 8, 528-533. Abstract.
Zhou Q, Dowling A, Heide H, Wöhnert J, Brandt U, Baum J, ffrench-Constant R, Bode HB (2012). Xentrivalpeptides A–Q: Depsipeptide Diversification in <i>Xenorhabdus</i>. Journal of Natural Products, 75(10), 1717-1722.
Felföldi G, Eleftherianos I, Ffrench-Constant RH, Venekei I (2011). A serine proteinase homologue, SPH-3, plays a central role in insect immunity. J Immunol, 186(8), 4828-4834. Abstract.  Author URL.
Smee M, Smyth W, Tunmore M, ffrench-Constant R, Hodgson D (2011). Butterflies on the brink: Habitat requirements for declining populations of the marsh fritillary (Euphydryas aurinia) in SW England. Journal of Insect Conservation, 15(1), 153-163. Abstract.
Smee M, Smyth W, Tunmore M, Ffrench-Constant R, Hodgson D (2011). Butterflies on the brink: habitat requirements for declining populations of the marsh fritillary (Euphydryas aurinia) in SW England. J INSECT CONSERV, 15(1-2), 153-163. Abstract.
Orth JHC, Schorch B, Boundy S, Ffrench-Constant R, Kubick S, Aktories K (2011). Cell-free synthesis and characterization of a novel cytotoxic pierisin-like protein from the cabbage butterfly Pieris rapae. Toxicon, 57(2), 199-207.
Orth JHC, Schorch B, Boundy S, Ffrench-Constant R, Kubick S, Aktories K (2011). Cell-free synthesis and characterization of a novel cytotoxic pierisin-like protein from the cabbage butterfly Pieris rapae. TOXICON, 57(2), 199-207. Author URL.
Joron M, Frezal L, Jones RT, Chamberlain NL, Lee SF, Haag CR, Whibley A, Becuwe M, Baxter SW, Ferguson L, et al (2011). Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry. NATURE, 477(7363), 203-U102. Author URL.
Proschak A, Schultz K, Herrmann J, Dowling AJ, Brachmann AO, ffrench-Constant R, Mueller R, Bode HB (2011). Cytotoxic Fatty Acid Amides from Xenorhabdus. CHEMBIOCHEM, 12(13), 2011-2015. Author URL.
Smith DT, Hosken DJ, Rostant WG, Yeo M, Griffin RM, Bretman A, Price TAR, Ffrench-Constant RH, Wedell N (2011). DDT resistance, epistasis and male fitness in flies. J Evol Biol, 24(6), 1351-1362. Abstract.  Author URL.
van Munster M, le Gleuher M, Pauchet Y, Augustin S, Courtin C, Amichot M, ffrench-Constant RH, Pauron D (2011). Molecular characterization of three genes encoding aminopeptidases N in the poplar leaf beetle Chrysomela tremulae. Insect Molecular Biology, 20(2), 267-278.
Karatolos N, Pauchet Y, Wilkinson P, Chauhan R, Denholm I, Gorman K, Nelson DR, Bass C, ffrench-Constant RH, Williamson MS, et al (2011). Pyrosequencing the transcriptome of the greenhouse whitefly, Trialeurodes vaporariorum reveals multiple transcripts encoding insecticide targets and detoxifying enzymes. BMC Genomics, 12 Abstract.
Terenius O, Papanicolaou A, Garbutt JS, Eleftherianos I, Huvenne H, Kanginakudru S, Albrechtsen M, an C, Aymeric J-L, Barthel A, et al (2011). RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. JOURNAL OF INSECT PHYSIOLOGY, 57(2), 231-245. Author URL.
Peat SM, ffrench-Constant RH, Waterfield NR, Marokházi J, Fodor A, Adams BJ (2010). A robust phylogenetic framework for the bacterial genus Photorhabdus and its use in studying the evolution and maintenance of bioluminescence: a case for 16S, gyrB, and glnA. Molecular Phylogenetics and Evolution, 57(2), 728-740.
Ferguson L, Lee SF, Chamberlain N, Nadeau N, Joron M, Baxter S, Wilkinson P, Papanicolaou A, Kumar S, Kee T-J, et al (2010). Characterization of a hotspot for mimicry: assembly of a butterfly wing transcriptome to genomic sequence at the HmYb/Sb locus. Mol Ecol, 19 Suppl 1, 240-254. Abstract.  Author URL.
Eleftherianos I, Ffrench-Constant RH, Clarke DJ, Dowling AJ, Reynolds SE (2010). Dissecting the immune response to the entomopathogen Photorhabdus. TRENDS IN MICROBIOLOGY, 18(12), 552-560. Author URL.
Pauchet Y, Wilkinson P, Chauhan R, Ffrench-Constant RH (2010). Diversity of beetle genes encoding novel plant cell wall degrading enzymes. PLoS ONE, 5(12). Abstract.
Dowling AJ, Wilkinson PA, Holden MTG, Quail MA, Bentley SD, Reger J, Waterfield NR, Titball RW, Ffrench-Constant RH (2010). Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen Burkholderia pseudomallei K96243. PLoS One, 5(12). Abstract.  Author URL.
Counterman BA, Araujo-Perez F, Hines HM, Baxter SW, Morrison CM, Lindstrom DP, Papa R, Ferguson L, Joron M, Ffrench-Constant RH, et al (2010). Genomic Hotspots for Adaptation: the Population Genetics of Mullerian Mimicry in Heliconius erato. PLOS GENETICS, 6(2). Author URL.
Counterman BA, Araujo-Perez F, Hines HM, Baxter SW, Morrison CM, Lindstrom DP, Papa R, Ferguson L, Joron M, Ffrench-Constant RH, et al (2010). Genomic hotspots for adaptation: the population genetics of Müllerian mimicry in Heliconius erato. PLoS Genet, 6(2). Abstract.  Author URL.
Baxter SW, Nadeau NJ, Maroja LS, Wilkinson P, Counterman BA, Dawson A, Beltran M, Perez-Espona S, Chamberlain N, Ferguson L, et al (2010). Genomic hotspots for adaptation: the population genetics of Müllerian mimicry in the Heliconius melpomene clade. PLoS Genet, 6(2). Abstract.  Author URL.
Jones RT, Bakker SE, Stone D, Shuttleworth SN, Boundy S, McCart C, Daborn PJ, Ffrench-Constant RH, van den Elsen JMH (2010). Homology modelling of Drosophila cytochrome P450 enzymes associated with insecticide resistance. PEST MANAGEMENT SCIENCE, 66(10), 1106-1115. Author URL.
Jones RT, Bakker SE, Stone D, Shuttleworth SN, Boundy S, McCart C, Daborn PJ, ffrench-Constant RH, van den Elsen JMH (2010). Homology modelling of Drosophila cytochrome P450 enzymes associated with insecticide resistance. Pest Manag Sci, 66(10), 1106-1115. Abstract.  Author URL.
Wilkinson P, Paszkiewicz K, Moorhouse A, Szubert JM, Beatson S, Gerrard J, Waterfield NR, Ffrench-Constant RH (2010). New plasmids and putative virulence factors from the draft genome of an Australian clinical isolate of Photorhabdus asymbiotica. FEMS Microbiol Lett, 309(2), 136-143. Abstract.  Author URL.
Jones RT, Sanchez-Contreras M, Vlisidou I, Amos MR, Yang G, Munoz-Berbel X, Upadhyay A, Potter UJ, Joyce SA, Ciche TA, et al (2010). Photorhabdus adhesion modification protein (Pam) binds extracellular polysaccharide and alters bacterial attachment. BMC MICROBIOLOGY, 10 Author URL.
Jones RT, Sanchez-Contreras M, Vlisidou I, Amos MR, Yang G, Muñoz-Berbel X, Upadhyay A, Potter UJ, Joyce SA, Ciche TA, et al (2010). Photorhabdus adhesion modification protein (Pam) binds extracellular polysaccharide and alters bacterial attachment. BMC Microbiol, 10 Abstract.  Author URL.
Eleftherianos I, Joyce S, Ffrench-Constant RH, Clarke DJ, Reynolds SE (2010). Probing the tri-trophic interaction between insects, nematodes and Photorhabdus. Parasitology, 137(11), 1695-1706. Abstract.  Author URL.
Pauchet Y, Wilkinson P, Vogel H, Nelson DR, Reynolds SE, Heckel DG, ffrench-Constant RH (2010). Pyrosequencing the Manduca sexta larval midgut transcriptome: messages for digestion, detoxification and defence. Insect Mol Biol, 19(1), 61-75. Abstract.  Author URL.
Metcalfe K, Ffrench-Constant R, Gordon I (2010). Sacred sites as hotspots for biodiversity: the Three Sisters Cave complex in coastal Kenya. ORYX, 44(1), 118-123. Abstract.
Vlisidou I, Eleftherianos I, Dorus S, Yang G, ffrench-Constant RH, Reynolds SE, Waterfield NR (2010). The KdpD/KdpE two-component system of Photorhabdus asymbiotica promotes bacterial survival within M. sexta hemocytes. J Invertebr Pathol, 105(3), 352-362. Abstract.  Author URL.
Eleftherianos I, Waterfield NR, Bone P, Boundy S, ffrench-Constant RH, Reynolds SE (2009). A single locus from the entomopathogenic bacterium Photorhabdus luminescens inhibits activated Manduca sexta phenoloxidase. FEMS Microbiol Lett, 293(2), 170-176. Abstract.  Author URL.
Wilkinson P, Waterfield NR, Crossman L, Corton C, Sanchez-Contreras M, Vlisidou I, Barron A, Bignell A, Clark L, Ormond D, et al (2009). Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens. BMC Genomics, 10 Abstract.  Author URL.
Vlisidou I, Dowling AJ, Evans IR, Waterfield N, ffrench-Constant RH, Wood W (2009). Drosophila embryos as model systems for monitoring bacterial infection in real time. PLoS Pathog, 5(7). Abstract.  Author URL.
Eleftherianos I, Felföldi G, ffrench-Constant RH, Reynolds SE (2009). Induced nitric oxide synthesis in the gut of<i>Manduca sexta</i>protects against oral infection by the bacterial pathogen<i>Photorhabdus luminescens</i>. Insect Molecular Biology, 18(4), 507-516.
Papanicolaou A, Stierli R, Ffrench-Constant RH, Heckel DG (2009). Next generation transcriptomes for next generation genomes using est2assembly. BMC Bioinformatics, 10 Abstract.  Author URL.
Ahantarig A, Chantawat N, Waterfield NR, ffrench-Constant R, Kittayapong P (2009). PirAB toxin from Photorhabdus asymbiotica as a larvicide against dengue vectors. Appl Environ Microbiol, 75(13), 4627-4629. Abstract.  Author URL.
Eleftherianos I, Xu M, Yadi H, Ffrench-Constant RH, Reynolds SE (2009). Plasmatocyte-spreading peptide (PSP) plays a central role in insect cellular immune defenses against bacterial infection. J Exp Biol, 212(Pt 12), 1840-1848. Abstract.  Author URL.
Pauchet Y, Wilkinson P, van Munster M, Augustin S, Pauron D, ffrench-Constant RH (2009). Pyrosequencing of the midgut transcriptome of the poplar leaf beetle Chrysomela tremulae reveals new gene families in Coleoptera. Insect Biochem Mol Biol, 39(5-6), 403-413. Abstract.  Author URL.
Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Yang G, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, et al (2009). Rapid Virulence Annotation (RVA): Identification of virulence factors using a bacterial genome library and multiple invertebrate hosts (vol 105, pg 15967, 2008). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(6), 2083-2083. Author URL.
Smith DT, Hosken DJ, Ffrench-Constant RH, Wedell N (2009). Variation in sex peptide expression in D. melanogaster. Genet Res (Camb), 91(4), 237-242. Abstract.  Author URL.
Zefania S, ffrench-Constant R, Long PR, Székely T (2008). Breeding distribution and ecology of the threatened Madagascar Plover. Charadrius thoracicus. Ostrich, 79(1), 43-51.
Baxter SW, Papa R, Chamberlain N, Humphray SJ, Joron M, Morrison C, ffrench-Constant RH, McMillan WO, Jiggins CD (2008). Convergent evolution in the genetic basis of Müllerian mimicry in heliconius butterflies. Genetics, 180(3), 1567-1577. Abstract.  Author URL.
Eleftherianos I, Baldwin H, ffrench-Constant RH, Reynolds SE (2008). Developmental modulation of immunity: changes within the feeding period of the fifth larval stage in the defence reactions of Manduca sexta to infection by Photorhabdus. J Insect Physiol, 54(1), 309-318. Abstract.  Author URL.
Long PR, Zefania S, Ffrench-Constant RH, Szekely T (2008). Estimating the population size of an endangered shorebird, the Madagascar plover, using a habitat suitability model. ANIMAL CONSERVATION, 11(2), 118-127. Author URL.
Papa R, Morrison CM, Walters JR, Counterman BA, Chen R, Halder G, Ferguson L, Chamberlain N, ffrench-Constant R, Kapan DD, et al (2008). Highly conserved gene order and numerous novel repetitive elements in genomic regions linked to wing pattern variation in Heliconius butterflies. BMC Genomics, 9(1), 345-345.
van Dijk RE, Komdeur J, van der Velde M, Szentirmai I, Yang X, Ffrench-Constant R, Székely T (2008). Offspring sex ratio in the sequentially polygamous Penduline Tit Remiz pendulinus. Journal of Ornithology, 149(4), 521-527.
Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Yang G, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, et al (2008). Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts. Proc Natl Acad Sci U S A, 105(41), 15967-15972. Abstract.  Author URL.
Lindsay HA, Baines R, ffrench-Constant R, Lilley K, Jacobs HT, O'Dell KMC (2008). The Dominant Cold-Sensitive Out-Cold Mutants of Drosophila melanogaster Have Novel Missense Mutations in the Voltage-Gated Sodium Channel Gene paralytic. GENETICS, 180(2), 873-884. Author URL.
Hares MC, Hinchliffe SJ, Strong PCR, Eleftherianos I, Dowling AJ, Ffrench-Constant RH, Waterfield N (2008). The Yersinia pseudotuberculosis and Yersinia pestis toxin complex is active against cultured mammalian cells. Microbiology (Reading), 154(Pt 11), 3503-3517. Abstract.  Author URL.
Iatrou K, Pierre (2007). 7<sup>th</sup>International Workshop on the Molecular Biology and Genetics of the Lepidoptera. Journal of Insect Science, 7(29), 1-5.
McCart, C. Woods, D.J. Terhzaz, S. (2007). A Drosophila systems approach to xenobiotic metabolism. Physiological Genomics, 30, 223-231.
Ffrench-Constant RH, Eleftherianos I, Reynolds SE (2007). A nematode symbiont sheds light on invertebrate immunity. Trends Parasitol, 23(11), 514-517. Abstract.  Author URL.
Sayed A, Nekl ER, Siqueira HAA, Wang H-C, Ffrench-Constant RH, Bagley M, Siegfried BD (2007). A novel cadherin-like gene from western corn rootworm, Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae), larval midgut tissue. Insect Mol Biol, 16(5), 591-600. Abstract.  Author URL.
Erickson DL, Waterfield NR, Vadyvaloo V, Long D, Fischer ER, ffrench-Constant R, Hinnebusch BJ (2007). Acute oral toxicity of Yersinia pseudotuberculosis to fleas: implications for the evolution of vector-borne transmission of plague. CELLULAR MICROBIOLOGY, 9(11), 2658-2666. Author URL.
Boundy, S. Joyce, S. Aslam, S. (2007). An antibiotic produced by an insect-pathogenic bacterium suppresses host defences through phenoloxidase inhibition. Proceedings of the National Academy of Sciences USA, 104, 2419-2424.
Bogwitz, M.R. McCart, C. Andrianopoulos, A. (2007). Cis-regulatory elements of the Accord retrotransposon result in tissue-specific expression of the Drosophila melanogaster insecticide resistance gene Cyp6g1. Genetics, 175, 1071-1077.
Chamberlain N, Baxter S, Jiggins C, Ffrench-Constant RH (2007). Dissecting butterfly wing pattern formation in Batesian and Mullerian mimicry. JOURNAL OF INSECT SCIENCE, 7 Author URL.
Lumb, C. Boey, A. Wong, W. (2007). Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression. Insect Biochemistry and Molecular Biology, 37, 512-519.
Baxter SW, Chamberlain N, Papa R, Humphray SJ, Ffrench-Constant RH, McMillan WO, Jiggins CD (2007). Identifying DNA markers close to quantitative traits in lepidopteran genomes: Using wing colour variation in Heliconius butterflies as a model. JOURNAL OF INSECT SCIENCE, 7 Author URL.
ffrench-Constant RH, Dowling A, Waterfield NR (2007). Insecticidal toxins from Photorhabdus bacteria and their potential use in agriculture. Toxicon, 49(4), 436-451. Abstract.  Author URL.
Eleftherianos I, Millichap PJ, Felfoldi G, Gokcen F, Waterfield N, Clarke DJ, Ffrench-Constant RH, Reynolds SE (2007). Probing the insect immune system with the entomopathogen Photorhabdus. JOURNAL OF INSECT SCIENCE, 7 Author URL.
Dowling AJ, Waterfield NR, Hares MC, Le Goff G, Streuli CH, ffrench-Constant RH (2007). The Mcf1 toxin induces apoptosis via the mitochondrial pathway and apoptosis is attenuated by mutation of the BH3-like domain. Cell Microbiol, 9(10), 2470-2484. Abstract.  Author URL.
Eleftherianos I, Gökçen F, Felföldi G, Millichap PJ, Trenczek TE, ffrench-Constant RH, Reynolds SE (2007). The immunoglobulin family protein Hemolin mediates cellular immune responses to bacteria in the insect Manduca sexta. Cell Microbiol, 9(5), 1137-1147. Abstract.  Author URL.
Waterfield N, Hares MC, Hinchliffe S, Wren B, ffrench-Constant R (2007). The insect Toxin complex of Yersinia. Ad Exp Med Biol, 603, 247-257.
Waterfield N, Hares M, Hinchliffe S, Wren B, ffrench-Constant R (2007). The insect toxin complex of Yersinia. Adv Exp Med Biol, 603, 247-257. Abstract.  Author URL.
Felfoldi G, Eleftherianos I, Ffrench-Constant RH, Venekei I, Reynolds SE (2007). The role of serineprotease homolgue 3 (SPH-3) in Manduca sexta shown by RNA interference. JOURNAL OF INSECT SCIENCE, 7 Author URL.
Ffrench-Constant RH (2007). Which came first: insecticides or resistance?. Trends Genet, 23(1), 1-4. Abstract.  Author URL.
Ffrench-Constant RH, Chamberlain N, Joron M, Papa R (2006). A conserved supergene locus controls colour pattern diversity in Heliconus butterflies. PLoS Biology, 4(10), 1831-1840.
Ffrench-Constant R, Waterfield N (2006). An ABC guide to the bacterial toxin complexes. Adv Appl Microbiol, 58, 169-183. Author URL.
KÜPPER C, HORSBURGH GJ, DAWSON DA, FFRENCH-CONSTANT R, SZÉKELY T, BURKE T (2006). Characterization of 36 polymorphic microsatellite loci in the Kentish plover (Charadrius alexandrinus) including two sex-linked loci and their amplification in four other Charadrius species. Molecular Ecology Notes, 7(1), 35-39.
ffrench-Constant RH, Waterfield NR (2006). Ground control for insect pests. Nat Biotechnol, 24(6), 660-661. Author URL.
Jenkins ATA, Dash H-A, Boundy S, Halliwell CM, ffrench-Constant RH (2006). Methoxy-resorufin ether as an electrochemically active biological probe for cytochrome P450 O-demethylation. Bioelectrochemistry, 68(1), 67-71. Abstract.  Author URL.
Gerrard JG, Joyce SA, Clarke DJ, ffrench-Constant RH, Nimmo GR, Looke DFM, Feil EJ, Pearce L, Waterfield NR (2006). Nematode symbiont for Photorhabdus asymbiotica. Emerg Infect Dis, 12(10), 1562-1564. Abstract.  Author URL.
Yang G, Dowling AJ, Gerike U, ffrench-Constant RH, Waterfield NR (2006). Photorhabdus virulence cassettes confer injectable insecticidal activity against the wax moth. J Bacteriol, 188(6), 2254-2261. Abstract.  Author URL.
Eleftherianos I, Marokhazi J, Millichap PJ, Hodgkinson AJ, Sriboonlert A, ffrench-Constant RH, Reynolds SE (2006). Prior infection of Manduca sexta with non-pathogenic Escherichia coli elicits immunity to pathogenic Photorhabdus luminescens: roles of immune-related proteins shown by RNA interference. Insect Biochem Mol Biol, 36(6), 517-525. Abstract.  Author URL.
Eleftherianos I, Millichap PJ, ffrench-Constant RH, Reynolds SE (2006). RNAi suppression of recognition protein mediated immune responses in the tobacco hornworm Manduca sexta causes increased susceptibility to the insect pathogen Photorhabdus. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 30(12), 1099-1107. Author URL.
Eleftherianos I, Millichap PJ, ffrench-Constant RH, Reynolds SE (2006). RNAi suppression of recognition protein mediated immune responses in the tobacco hornworm Manduca sexta causes increased susceptibility to the insect pathogen Photorhabdus. Dev Comp Immunol, 30(12), 1099-1107. Abstract.  Author URL.
ffrench-Constant R, Daborn P, Feyereisen R (2006). Resistance and the jumping gene. Bioessays, 28(1), 6-8. Abstract.  Author URL.
Le Goff G, Hilliou F, Siegfried BD, Boundy S, Wajnberg E, Sofer L, Audant P, Ffrench-Constant RH, Feyereisen R (2006). Xenobiotic response in Drosophila melanogaster: Sex dependence of P450 and GST gene induction. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 36(8), 674-682. Author URL.
Le Goff G, Hilliou F, Siegfried BD, Boundy S, Wajnberg E, Sofer L, Audant P, ffrench-Constant RH, Feyereisen R (2006). Xenobiotic response in Drosophila melanogaster: sex dependence of P450 and GST gene induction. Insect Biochem Mol Biol, 36(8), 674-682. Abstract.  Author URL.
Ffrench-Constant R, Waterfield N (2005). An ABC Guide to the Bacterial Toxin Complexes. Adv Appl Microbiol, 58C, 169-183. Author URL.
Buckling A, Neilson J, Lindsay J, ffrench-Constant R, Enright M, Day N, Massey RC (2005). Clonal distribution and phase-variable expression of a major histocompatibility complex analogue protein in Staphylococcus aureus. J Bacteriol, 187(8), 2917-2919. Abstract.  Author URL.
Buckling, A. McGhee, M. ffrench-constant, R.H. (2005). DDT resistance in flies carries no cost. Current Biology, 15(15), 587-589.
McCart C, Buckling A, Ffrench-Constant RH (2005). DDT resistance in flies carries no cost. Curr Biol, 15(15), R587-R589. Author URL.
Siegfried BD, Waterfield N, ffrench-Constant RH (2005). Expressed sequence tags from Diabrotica virgifera virgifera midgut identify a coleopteran cadherin and a diversity of cathepsins. INSECT MOLECULAR BIOLOGY, 14(2), 137-143. Author URL.
Siegfried BD, Waterfield N, ffrench-Constant RH (2005). Expressed sequence tags from Diabrotica virgifera virgifera midgut identify a coleopteran cadherin and a diversity of cathepsins. Insect Mol Biol, 14(2), 137-143. Abstract.  Author URL.
Eleftherianos I, ffrench-Constant RH, Reynolds SE (2005). Modulating lepidopteran immunity to bacteria using pre-infection and RNA interference. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 141(3), S109-S109. Author URL.
Waterfield N, Hares M, Yang G, Dowling A, ffrench-Constant R (2005). Potentiation and cellular phenotypes of the insecticidal Toxin complexes of Photorhabdus bacteria. Cell Microbiol, 7(3), 373-382. Abstract.  Author URL.
Ffrench-Constant RH (2005). Something old, something transgenic, or something fungal for mosquito control?. Trends Ecol Evol, 20(11), 577-579. Abstract.  Author URL.
Jenkins ATA, Buckling A, McGhee M, ffrench-Constant RH (2005). Surface plasmon resonance shows that type IV pili are important in surface attachment by Pseudomonas aeruginosa. J R Soc Interface, 2(3), 255-259. Abstract.  Author URL.
Waterfield N, Kamita SG, Hammock BD, ffrench-Constant R (2005). The Photorhabdus Pir toxins are similar to a developmentally regulated insect protein but show no juvenile hormone esterase activity. FEMS Microbiol Lett, 245(1), 47-52. Abstract.  Author URL.
NICE CC, ANTHONY N, GELEMBIUK G, RATERMAN D, FFRENCH-CONSTANT R (2005). The history and geography of diversification within the butterfly genus Lycaeides in North America. Molecular Ecology, 14(6), 1741-1754.
Daborn P, McCart C, Woods D, ffrench-Constant RH (2004). Detection of insecticide resistance-associated mutations in cat flea Rdl by TaqMan-allele specific amplification. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 79(1), 25-30. Author URL.
Au C, Dean P, Reynolds SE, ffrench-Constant RH (2004). Effect of the insect pathogenic bacterium Photorhabdus on insect phagocytes. Cell Microbiol, 6(1), 89-95. Abstract.  Author URL.
Gerrard J, Waterfield N, Vohra R, ffrench-Constant R (2004). Human infection with Photorhabdus asymbiotica: an emerging bacterial pathogen. Microbes and Infection, 6(2), 229-237.
Massey RC, Buckling A, Ffrench-Constant R (2004). Interference competition and parasite virulence. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 271(1541), 785-788. Author URL.
Massey RC, Buckling A, ffrench-Constant R (2004). Interference competition and parasite virulence. Proc Biol Sci, 271(1541), 785-788. Abstract.  Author URL.
Waterfield NR, Wren BW, Ffrench-Constant RH (2004). Invertebrates as a source of emerging human pathogens. Nat Rev Microbiol, 2(10), 833-841. Abstract.  Author URL.
Anthony N, Gelembiuk G, Raterman D, Nice C, Ffrench-Constant R (2004). Isolation and Characterization of Microsatellite Markers from the Endangered Karner Blue Butterfly Lycaeides Melissa Samuelis (Lepidoptera). Hereditas, 134(3), 271-273.
Jenkins ATA, Ffrench-Constant R, Buckling A, Clarke DJ, Jarvis K (2004). Study of the attachment of Pseudomonas aeruginosa on gold and modified gold surfaces using surface plasmon resonance. BIOTECHNOLOGY PROGRESS, 20(4), 1233-1236. Author URL.
Jenkins ATA, ffrench-constant R, Buckling A, Clarke DJ, Jarvis K (2004). Study of the attachment of Pseudomonas aeruginosa on gold and modified gold surfaces using surface plasmon resonance. Biotechnol Prog, 20(4), 1233-1236. Abstract.  Author URL.
Ffrench-Constant RH, Daborn PJ, Le Goff G (2004). The genetics and genomics of insecticide resistance. Trends Genet, 20(3), 163-170. Abstract.  Author URL.
Ffrench-Constant RH, Daborn PJ, Dowling AJ, Steuli CH (2004). The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells. Cellular Microbiology, 6(4), 345-353.
Dowling AJ, Daborn PJ, Waterfield NR, Wang P, Streuli CH, ffrench-Constant RH (2004). The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells. CELLULAR MICROBIOLOGY, 6(4), 345-353. Author URL.
Catania, F. Kauer, M.O. (2004). World-wide survey of an Accord insertion and its association with DDT resistance in Drosophila Melanogaster. Molecular Ecology, 13(8), 2491-2504.
Ffrench-Constant R, Waterfield N, Daborn P, Joyce S, Bennett H, Au C, Dowling A, Boundy S, Reynolds S, Clarke D, et al (2003). <i>Photorhabdus</i>: towards a functional genomic analysis of a symbiont and pathogen. FEMS Microbiology Reviews, 26(5), 433-456.
Bowen DJ, Rocheleau TA, Grutzmacher CK, Meslet L, Valens M, Marble D, Dowling A, Ffrench-Constant R, Blight MA (2003). Genetic and biochemical characterization of PrtA, an RTX-like metalloprotease from Photorhabdus. Microbiology (Reading), 149(Pt 6), 1581-1591. Abstract.  Author URL.
Le Goff G, Boundy S, Daborn PJ, Yen JL, Sofer L, Lind R, Sabourault C, Madi-Ravazzi L, ffrench-Constant RH (2003). Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila. Insect Biochem Mol Biol, 33(7), 701-708. Abstract.  Author URL.
ffrench-Constant R, Waterfield N, Daborn P, Joyce S, Bennett H, Au C, Dowling A, Boundy S, Reynolds S, Clarke D, et al (2003). Photorhabdus: towards a functional genomic analysis of a symbiont and pathogen. FEMS Microbiol Rev, 26(5), 433-456. Abstract.  Author URL.
DeCamillis M, ffrench-Constant R (2003). Proboscipedia represses distal signaling in the embryonic gnathal limb fields of Tribolium castaneum. Dev Genes Evol, 213(2), 55-64. Abstract.  Author URL.
Waterfield N, Daborn P, Dowling A, Yang G, Hares MC, ffrench-Constant R (2003). The insecticidal toxin Makes Caterpillars floppy 2 (Mcf2) shows similarity to HrmA, a virulence protein from a plant pathogen. Fems Microbiol Letts, 229, 265-270.
Waterfield NR, Daborn PJ, Dowling AJ, Yang G, Hares M, ffrench-Constant RH (2003). The insecticidal toxin makes caterpillars floppy 2 (Mcf2) shows similarity to HrmA, an avirulence protein from a plant pathogen. FEMS Microbiol Lett, 229(2), 265-270. Abstract.  Author URL.
Marokhazi J, Waterfield N, LeGoff G, Feil E, Stabler R, Hinds J, Fodor A, ffrench-Constant RH (2003). Using a DNA microarray to investigate the distribution of insect virulence factors in strains of photorhabdus bacteria. J Bacteriol, 185(15), 4648-4656. Abstract.  Author URL.
Ffrench-Constant RH, Bogwitz M, Daborn PJ, Yen JL (2002). A single P450 allele associated with insecticide resistance in Drosophila. Science, 297(5590), 2253-2256.
Ffrench-Constant RH, Daborn PJ, Silva CP, Waterfield N (2002). A single Photorhabdus gene, makes caterpillars floppy (mfc), allows Escherichia coli to persist within and kill insects. Proceedings of the National Academy of Sciences, 99(16), 10742-10747.
Silva CP, Waterfield NR, Daborn PJ, Dean P, Chilver T, Au CPY, Sharma S, Potter U, Reynolds SE, ffrench-Constant RH, et al (2002). Bacterial infection of a model insect: Photorhabdus luminescens and Manduca sexta. Cell Microbiol, 4(6), 329-339. Abstract.  Author URL.
Waterfield NR, Daborn PJ, ffrench-Constant RH (2002). Genomic islands in Photorhabdus. Trends Microbiol, 10(12), 541-545. Abstract.  Author URL.
Andreasen MH, Ffrench-Constant RH (2002). In situ hybridization to the Rdl locus on polytene chromosome 3L of Anopheles stephensi. Med Vet Entomol, 16(4), 452-455. Abstract.  Author URL.
Nice CC, Fordyce JA, Shapiro AM, Ffrench-Constant R (2002). Lack of evidence for reproductive isolation among ecologically specialised lycaenid butterflies. Ecological Entomology, 27(6), 702-712.
Sharma S, Waterfield N, Bowen D, Rocheleau T, Holland L, James R, ffrench-Constant R (2002). The lumicins: novel bacteriocins from Photorhabdus luminescens with similarity to the uropathogenic-specific protein (USP) from uropathogenic Escherichia coli. FEMS MICROBIOLOGY LETTERS, 214(2), 241-249. Author URL.
Sharma S, Waterfield N, Bowen D, Rocheleau T, Holland L, James R, ffrench-Constant R (2002). The lumicins: novel bacteriocins from Photorhabdus luminescens with similarity to the uropathogenic-specific protein (USP) from uropathogenic Escherichia coli. FEMS Microbiol Lett, 214(2), 241-249. Abstract.  Author URL.
Daborn P, Boundy S, Yen J, Pittendrigh B, ffrench-Constant R (2001). DDT resistance in Drosophila correlates with Cyp6g1 over-expression and confers cross-resistance to the neonicotinoid imidacloprid. Mol Genet Genomics, 266(4), 556-563. Abstract.  Author URL.
Daborn PJ, Waterfield N, Blight MA, Ffrench-Constant RH (2001). Measuring virulence factor expression by the pathogenic bacterium Photorhabdus luminescens in culture and during insect infection. J Bacteriol, 183(20), 5834-5839. Abstract.  Author URL.
Waterfield N, Dowling A, Sharma S, Daborn PJ, Potter U, Ffrench-Constant RH (2001). Oral toxicity of Photorhabdus luminescens W14 toxin complexes in Escherichia coli. Appl Environ Microbiol, 67(11), 5017-5024. Abstract.  Author URL.
Waterfield NR, Bowen DJ, Fetherston JD, Perry RD, ffrench-Constant RH (2001). The tc genes of Photorhabdus: a growing family. Trends Microbiol, 9(4), 185-191. Abstract.  Author URL.
Ffrench-Constant RH, Waterfield N, Burland V, Perna NT, Daborn PJ, Bowen D, Blattner FR (2000). A genomic sample sequence of the entomopathogenic bacterium Photorhabdus luminescens W14: potential implications for virulence. Appl Environ Microbiol, 66(8), 3310-3329. Abstract.  Author URL.
Koch PB, Lorenz U, Brakefield PM, ffrench-Constant RH (2000). Butterfly wing pattern mutants: developmental heterochrony and co-ordinately regulated phenotypes. Dev Genes Evol, 210(11), 536-544. Abstract.  Author URL.
(2000). Cloning, sequencing and functional expression of an acetylcholinesterase gene from the yellow fever mosquito<i>Aedes aegypti</i>. FEBS Letters, 368(3), 461-465.
Ffrench-Constant RH, Anthony N, Aronstein K, Rocheleau T, Stilwell G (2000). Cyclodiene insecticide resistance: from molecular to population genetics. Annu Rev Entomol, 45, 449-466. Abstract.  Author URL.
ffrench-Constant RH, Bowen DJ (2000). Novel insecticidal toxins from nematode-symbiotic bacteria. Cell Mol Life Sci, 57(5), 828-833. Abstract.  Author URL.
Martin RL, Pittendrigh B, Liu J, Reenan R, ffrench-Constant R, Hanck DA (2000). Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin. Insect Biochemistry and Molecular Biology, 30(11), 1051-1059.
Coustau C, Chevillon C, ffrench-Constant R (2000). Resistance to xenobiotics and parasites: can we count the cost?. Trends in Ecology & Evolution, 15(9), 378-383.
Bowen D, Blackburn M, Rocheleau T, Grutzmacher C, ffrench-Constant RH (2000). Secreted proteases from Photorhabdus luminescens: separation of the extracellular proteases from the insecticidal Tc toxin complexes. Insect Biochem Mol Biol, 30(1), 69-74. Abstract.  Author URL.
Koch PB, Behnecke B, ffrench-Constant RH (2000). The molecular basis of melanism and mimicry in a swallowtail butterfly. Curr Biol, 10(10), 591-594. Abstract.  Author URL.
Crennell SJ, Tickler PM, Bowen DJ, ffrench-Constant RH (2000). The predicted structure of photopexin from Photorhabdus shows the first haemopexin-like motif in prokaryotes. FEMS Microbiol Lett, 191(1), 139-144. Abstract.  Author URL.
Wang CT, Zhang HG, Rocheleau TA, ffrench-Constant RH, Jackson MB (1999). Cation permeability and cation-anion interactions in a mutant GABA-gated chloride channel from Drosophila. Biophys J, 77(2), 691-700. Abstract.  Author URL.
Bowen D, Blackburn M, Rocheleau TA, Andreev O, Golubeva E, ffrench‐Constant RH (1999). Insecticidal toxins from the bacterium Photorhabdus luminescens: gene cloning and toxin histopathology. Pest Management Science, 55(6), 666-668.
Andreev D, Kreitman M, Phillips TW, Beeman RW, ffrench-Constant RH (1999). Multiple origins of cyclodiene insecticide resistance in Tribolium castaneum (Coleoptera: Tenebrionidae). J Mol Evol, 48(5), 615-624. Abstract.  Author URL.
ffrench-Constant R, Bowen D (1999). Photorhabdus toxins: novel biological insecticides. Curr Opin Microbiol, 2(3), 284-288. Abstract.  Author URL.
ffrench-Constant RH (1999). Target site mediated insecticide resistance: what questions remain?. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 29(5), 397-403. Author URL.
Blackburn M, Golubeva E, Bowen D, Ffrench-Constant RH (1998). A novel insecticidal toxin from photorhabdus luminescens, toxin complex a (Tca), and its histopathological effects on the midgut of manduca sexta. Appl Environ Microbiol, 64(8), 3036-3041. Abstract.  Author URL.
Liu HT, Stilwell G, Anthony N, Rocheleau T, ffrench-Constant RH (1998). Analysis of a mosquito acetylcholinesterase gene promoter. Insect Mol Biol, 7(1), 11-17. Abstract.  Author URL.
Vaughan A, Chadee DD, French-Constant R (1998). Biochemical monitoring of organophosphorus and carbamate insecticide resistance in Aedes aegypti mosquitoes from Trinidad. Med Vet Entomol, 12(3), 318-321. Author URL.
Anthony NM, Brown JK, Feyereisen R, ffrench-Constant RH (1998). Diagnosis and characterization of insecticide-insensitive acetylcholinesterase in three populations of the sweetpotato whitefly Bemisia tabaci. PESTICIDE SCIENCE, 52(1), 39-46. Author URL.
Anthony N, Unruh T, Ganser D, ffrench-Constant R (1998). Duplication of the Rdl GABA receptor subunit gene in an insecticide-resistant aphid, Myzus persicae. Mol Gen Genet, 260(2-3), 165-175. Abstract.  Author URL.
Bowen D, Rocheleau TA, Blackburn M, Andreev O, Golubeva E, Bhartia R, ffrench-Constant RH (1998). Insecticidal toxins from the bacterium Photorhabdus luminescens. Science, 280(5372), 2129-2132. Abstract.  Author URL.
Andreev D, Breilid H, Kirkendall L, Brun LO, ffrench-Constant RH (1998). Lack of nucleotide variability in a beetle pest with extreme inbreeding. Insect Mol Biol, 7(2), 197-200. Abstract.  Author URL.
Koch PB, Keys DN, Rocheleau T, Aronstein K, Blackburn M, Carroll SB, ffrench-Constant RH (1998). Regulation of dopa decarboxylase expression during colour pattern formation in wild-type and melanic tiger swallowtail butterflies. Development, 125(12), 2303-2313. Abstract.  Author URL.
Stilwell GE, ffrench-Constant RH (1998). Transcriptional analysis of the Drosophila GABA receptor gene resistance to dieldrin. J Neurobiol, 36(4), 468-484. Abstract.  Author URL.
Pittendrigh B, Aronstein K, Zinkovsky E, Andreev O, Campbell B, Daly J, Trowell S, Ffrench-Constant RH (1997). Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain. Insect Biochem Mol Biol, 27(6), 507-512. Abstract.  Author URL.
Hosie AM, Aronstein K, Sattelle DB, ffrench-Constant RH (1997). Molecular biology of insect neuronal GABA receptors. Trends Neurosci, 20(12), 578-583. Abstract.  Author URL.
Severson DW, Anthony NM, Andreev O, ffrench-Constant RH (1997). Molecular mapping of insecticide resistance genes in the yellow fever mosquito (Aedes aegypti). J Hered, 88(6), 520-524. Abstract.  Author URL.
Pittendrigh B, Reenan R, ffrench-Constant RH, Ganetzky B (1997). Point mutations in the Drosophila sodium channel gene para associated with resistance to DDT and pyrethroid insecticides. Mol Gen Genet, 256(6), 602-610. Abstract.  Author URL.
Vaughan A, Rocheleau T, ffrench-Constant R (1997). Site-directed mutagenesis of an acetylcholinesterase gene from the yellow fever mosquito Aedes aegypti confers insecticide insensitivity. Exp Parasitol, 87(3), 237-244. Abstract.  Author URL.
Dunkov BC, Guzov VM, Mocelin G, Shotkoski F, Brun A, Amichot M, Ffrench-Constant RH, Feyereisen R (1997). The Drosophila cytochrome P450 gene Cyp6a2: structure, localization, heterologous expression, and induction by phenobarbital. DNA Cell Biol, 16(11), 1345-1356. Abstract.  Author URL.
Brotz TM, Bochenek B, Aronstein K, Ffrench-Constant RH, Borst A (1997). gamma-Aminobutyric acid receptor distribution in the mushroom bodies of a fly (Calliphora erythrocephala): a functional subdivision of Kenyon cells?. J Comp Neurol, 383(1), 42-48. Abstract.  Author URL.
Dunkov BC, Rodriguez-Arnaiz R, Pittendrigh B, ffrench-Constant RH, Feyereisen R (1996). Cytochrome P450 gene clusters in. MGG Molecular & General Genetics, 251(3), 290-290.
Dunkov BC, Rodriguez-Arnaiz R, Pittendrigh B, ffrench-Constant RH, Feyereisen R (1996). Cytochrome P450 gene clusters in Drosophila melanogaster. Mol Gen Genet, 251(3), 290-297. Abstract.  Author URL.
Coustau C, Carkion Y, Nappi A, Shotkoski F, ffrench-Constant R (1996). Differential induction of antibacterial transcripts in Drosophila susceptible and resistant to parasitism by Leptopilina boulardi. Insect Mol Biol, 5(3), 167-172. Abstract.  Author URL.
Aronstein K, Auld V, Ffrench-Constant R (1996). Distribution of two GABA receptor-like subunits in the Drosophila CNS. Invert Neurosci, 2(2), 115-120. Abstract.  Author URL.
ffrench-Constant R (1996). Ecological and evolutionary aspects of insecticide resistance by John A. McKenzie Academic Press, 1996. £52.00 hbk (185 pages) ISBN 0 12 484825 7. Trends in Ecology & Evolution, 11(9), 391-392.
Shotkoski F, Morris AC, James AA, ffrench-Constant RH (1996). Functional analysis of a mosquito gamma-aminobutyric acid receptor gene promoter. Gene, 168(2), 127-133. Abstract.  Author URL.
Coustau C, Rocheleau T, Carton Y, Nappi AJ, ffrench-Constant RH (1996). Induction of a putative serine protease transcript in immune challenged Drosophila. Dev Comp Immunol, 20(4), 265-272. Abstract.  Author URL.
Hidayat P, Phillips TW, Ffrench-Constant RH (1996). Molecular and Morphological Characters Discriminate Sitophilus oryzae and S. zeamais (Coleoptera: Curculionidae) and Confirm Reproductive Isolation. Annals of the Entomological Society of America, 89(5), 645-652.
Shotkoski F, Zhang HG, Jackson MB, ffrench-Constant RH (1996). Stable expression of insect GABA receptors in insect cell lines. Promoters for efficient expression of Drosophila and mosquito Rdl GABA receptors in stably transformed mosquito cell lines. FEBS Lett, 380(3), 257-262. Abstract.  Author URL.
Pittendrigh BR, Mocelin G, Andreev O, ffrench-Constant RH (1996). The sequence of a Drosophila Cyp4e2 cytochrome P450-encoding cDNA. Gene, 179(2), 295-296. Abstract.  Author URL.
Brun LO, Borsa P, Gaudichon V, Stuart JJ, Aronstein K, Coustau C, ffrench-Constant RH (1995). 'Functional' haplodiploidy. Nature, 374(6522), 506-506.
Coustau C, ffrench‐Constant R (1995). Detection of cyclodiene insecticide resistance‐associated mutations by single‐stranded conformational polymorphism analysis. Pest Management Science, 43(4), 267-271.
Brun LO, Stuart J, Gaudichon V, Aronstein K, French-Constant RH (1995). Functional haplodiploidy: a mechanism for the spread of insecticide resistance in an important international insect pest. Proceedings of the National Academy of Sciences, 92(21), 9861-9865. Abstract.
Stilwell GE, Rocheleau T, ffrench-Constant RH (1995). GABA receptor minigene rescues insecticide resistance phenotypes in Drosophila. J Mol Biol, 253(2), 223-227. Abstract.  Author URL.
Aronstein K, Ffrench-Constant R (1995). Immunocytochemistry of a novel GABA receptor subunit Rdl in Drosophila melanogaster. Invert Neurosci, 1(1), 25-31. Abstract.  Author URL.
Aronstein K, Ode P, ffrench-Constant RH (1995). PCR based monitoring of specific Drosophila (Diptera: Drosophilidae) cyclodiene resistance alleles in the presence and absence of selection. Bulletin of Entomological Research, 85(1), 5-9.
Ffrench‐Constant R, Aronstein K, Anthony N, Coustau C (1995). Polymerase chain reaction‐based monitoring techniques for the detection of insecticide resistance‐associated point mutations and their potential applications. Pest Management Science, 43(3), 195-200.
Al-Aboodi A, Ffrench-Constant RH (1995). RAPD PCR confirms absence of genetic variation between insecticide resistant variants of the green peach aphid, Myzus persicae (Homoptera: Aphididae). Great Lakes entomologist., 28(2), 127-133.
Zhang HG, Lee HJ, Rocheleau T, ffrench-Constant RH, Jackson MB (1995). Subunit composition determines picrotoxin and bicuculline sensitivity of Drosophila gamma-aminobutyric acid receptors. Mol Pharmacol, 48(5), 835-840. Abstract.  Author URL.
FFRENCH‐CONSTANT RH (1995). The Zap Trap. The Sciences, 35(2), 31-35.
Andreev D, Rocheleau T, Phillips TW, Beeman RW, ffrench‐Constant RH (1994). A PCR diagnostic for cyclodiene insecticide resistance in the red flour beetle Tribolium castaneum. Pest Management Science, 41(4), 345-349.
ffrench-Constant RH, Steichen JC, Brun LO (1994). A molecular diagnostic for endosulfan insecticide resistance in the coffee berry borer Hypothenemus hampei (Coleoptera: Scolytidae). Bulletin of Entomological Research, 84(1), 11-15.
Zhang HG, ffrench-Constant RH, Jackson MB (1994). A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms. J Physiol, 479 ( Pt 1), 65-75. Abstract.  Author URL.
Shotkoski F, Lee HJ, Zhang HG, Jackson MB, ffrench-Constant RH (1994). Functional expression of insecticide-resistant GABA receptors from the mosquito Aedes aegypti. Insect Mol Biol, 3(4), 283-287. Abstract.  Author URL.
Ffrench-Constant RH, Steichen JC, Shotkoski F (1994). Polymerase chain reaction diagnostic for cyclodiene insecticide resistance in the mosquito Aedes aegypti. Med Vet Entomol, 8(1), 99-100. Author URL.
Ffrench-Constant RH (1994). The molecular and population genetics of cyclodiene insecticide resistance. Insect Biochem Mol Biol, 24(4), 335-345. Abstract.  Author URL.
Ffrench-Constant RH, Rocheleau TA, Steichen JC, Chalmers AE (1993). A point mutation in a Drosophila GABA receptor confers insecticide resistance. Nature, 363(6428), 449-451. Abstract.  Author URL.
ffrench-Constant RH, Steichen JC, Rocheleau TA, Aronstein K, Roush RT (1993). A single-amino acid substitution in a gamma-aminobutyric acid subtype a receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations. Proc Natl Acad Sci U S A, 90(5), 1957-1961. Abstract.  Author URL.
Thompson M, Shotkoski F, ffrench-Constant R (1993). Cloning and sequencing of the cyclodiene insecticide resistance gene from the yellow fever mosquito Aedes aegypti. Conservation of the gene and resistance associated mutation with Drosophila. FEBS Lett, 325(3), 187-190. Abstract.  Author URL.
ffrench-Constant RH (1993). Cloning of a putative GABAA receptor from cyclodiene-resistant Drosophila: a case study in the use of insecticide-resistant mutants to isolate neuroreceptors. EXS, 63, 210-223. Abstract.  Author URL.
Ffrench-Constant RH (1993). Cloning of the Drosophila cyclodiene insecticide resistance gene: a novel GABAA receptor subtype?. Comp Biochem Physiol C Comp Pharmacol Toxicol, 104(1), 9-12. Abstract.  Author URL.
Thompson M, Steichen JC, ffrench-Constant RH (1993). Conservation of cyclodiene insecticide resistance-associated mutations in insects. Insect Mol Biol, 2(3), 149-154. Abstract.  Author URL.
ffrench-Constant RH, Rocheleau TA (1993). Drosophila gamma-aminobutyric acid receptor gene Rdl shows extensive alternative splicing. J Neurochem, 60(6), 2323-2326. Abstract.  Author URL.
Lee HJ, Rocheleau T, Zhang HG, Jackson MB, ffrench-Constant RH (1993). Expression of a Drosophila GABA receptor in a baculovirus insect cell system. Functional expression of insecticide susceptible and resistant GABA receptors from the cyclodiene resistance gene Rdl. FEBS Lett, 335(3), 315-318. Abstract.  Author URL.
Ffrench-Constant RH, Roush RT (1992). Cloning of a locus associated with cyclodiene resistance in Drosophila: a model system in a model insect. ACS symposium series. American Chemical Society(505), 90-98. Abstract.
ffrench-Constant RH, Rocheleau T (1992). Drosophila cyclodiene resistance gene shows conserved genomic organization with vertebrate gamma-aminobutyric acidA receptors. J Neurochem, 59(4), 1562-1565. Abstract.  Author URL.
Bloomquist JR, Roush RT, ffrench-Constant RH (1992). Reduced neuronal sensitivity to dieldrin and picrotoxinin in a cyclodiene-resistant strain of Drosophila melanogaster (Meigen). Arch Insect Biochem Physiol, 19(1), 17-25. Abstract.  Author URL.
ffrench-Constant RH, Aronstein K, Roush RT (1992). Use of a P-element mediated germline transformant to study the effect of gene dosage in cyclodiene insecticide-resistant Drosophila melanogaster (Meigen). Pesticide Biochemistry and Physiology, 43(1), 78-84.
Bloomquist JR, Ffrench‐Constant RH, Roush RT (1991). Excitation of central neurons by dieldrin and picrotoxinin in susceptible and resistant Drosophila melanogaster (meigen). Pest Management Science, 32(4), 463-469.
Ffrench-Constant RH, Roush RT (1991). Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.). Genet Res, 57(1), 17-21. Abstract.  Author URL.
Ffrench-Constant RH, Mortlock DP, Shaffer CD, MacIntyre RJ, Roush RT (1991). Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate gamma-aminobutyric acid subtype a receptor locus. Proc Natl Acad Sci U S A, 88(16), 7209-7213. Abstract.  Author URL.
Ffrench-Constant RH, Roush RT, Mortlock D, Dively GP (1990). Isolation of dieldrin resistance from field populations of Drosophila melanogaster (Diptera: Drosophilidae). J Econ Entomol, 83(5), 1733-1737. Abstract.  Author URL.
Lines JD, ffRench-Constant RH, Kasim SH (1990). Testing Anopheles albimanus for genetic linkage of insecticide resistance genes by combining insecticide bioassay and biochemical methods. Med Vet Entomol, 4(4), 445-450. Abstract.  Author URL.
Field LM, Devonshire AL, Ffrench-Constant RH, Forde BG (1989). Changes in DNA methylation are associated with loss of insecticide resistance in the peach‐potato aphid Myzus persicae (Sulz.). FEBS Letters, 243(2), 323-327.
Moores GD, Ffrench‐Constant RH, Devonshire AL (1989). Immunoassay for detecting insecticide resistance in aphids. Pest Management Science, 26(3), 324-326.
Ffrench-Constant RH, Bonning BC (1989). Rapid microtitre plate test distinguishes insecticide resistant acetylcholinesterase genotypes in the mosquitoes Anopheles albimanus, An. nigerrimus and Culex pipiens. Med Vet Entomol, 3(1), 9-16. Abstract.  Author URL.
Harrington R, Bartlet E, Riley DK, ffrench-Constant RH, Clark SJ (1989). Resurgence of insecticide-resistant Myzus persicae on potatoes treated repeatedly with cypermethrin and mineral oil. Crop Protection, 8(5), 340-348.
Field LM, Devonshire AL, ffrench-Constant RH, Forde BG (1989). The combined use of immunoassay and a DNA diagnostic technique to identify insecticide-resistant genotypes in the peach-potato aphid, Myzus persicae (Sulz.). Pesticide Biochemistry and Physiology, 34(2), 174-178.
Ffrench-Constant RH, Clark SJ, Devonshire AL (1988). Effect of decline of insecticide residues on selection for insecticide resistance in Myzus persicae (Sulzer) (Hemiptera: Aphididae). Bulletin of Entomological Research, 78(1), 19-29.
ffrench-Constant RH, Harrington R, Devonshire AL (1988). Effect of repeated applications of insecticides to potatoes on numbers of Myzus persicae (Sulzer) (Hemiptera: Aphididae) and on the frequencies of insecticide-resistant variants. Crop Protection, 7(1), 55-61.
French-Constant RH, Byrne FJ, Stribley MF, Devonshire AL (1988). Rapid identification of the recently recognised Myzus antirrhinii (Macchiati) (Hemiptera: Aphididae) by polyacrylamide gel electrophoresis. Entomologist., 107(1), 20-23.
Ffrench-Constant RH, Devonshire AL, White RP (1988). Spontaneous loss and reselection of resistance in extremely resistant Myzus persicae (Sulzer). Pesticide Biochemistry and Physiology, 30(1), 1-10.
ffrench-Constant RH, Devonshire AL (1987). A multiple homogenizer for rapid sample preparation in immunoassays and electrophoresis. Biochem Genet, 25(7-8), 493-499. Abstract.  Author URL.
Ffrench-Constant RH, Devonshire AL, Clark SJ (1987). Differential rate of selection for resistance by carbamate, organophosphorus and combined pyrethroid and organophosphorus insecticides in Myzus persicae (sulzer) (Hemiptera: Aphididae). Bulletin of Entomological Research, 77(2), 227-238.
Devonshire AL, Moores GD, Ffrench-Constant RH (1986). Detection of insecticide resistance by immunological estimation of carboxylesterase activity in Myzus persicae (Sulzer) and cross reaction of the antiserum with Phorodon humuli (Schrank) (Hemiptera: Aphididae). Bulletin of Entomological Research, 76(1), 97-107.
Ffrench-Constant RH, Devonshire AL (1986). The effect of aphid immigration on the rate of selection of insecticide resistance in Myzus persicae by different classes of insecticides. Aspects of applied biology(13), 115-125.

Chapters

ffrench-Constant RH (2018). Introductory Chapter: Butterfly Wing Patterns: Not Just Painting by Numbers. In  (Ed) Butterfly Wing Patterns and Mimicry, ix-xiii.
ffrench-Constant R, Waterfield N, Daborn P (2017). Insecticidal Toxins from Photorhabdus and Xenorhabdus ☆. In  (Ed) Reference Module in Life Sciences, 704-715.
ffrench-Constant RH, Dowling AJ (2014). Chapter Seven Photorhabdus Toxins. In  (Ed) Insect Midgut and Insecticidal Proteins, 343-388.
Smee M, Smyth W, Tunmore M, ffrench-Constant R, Hodgson D (2010). Butterflies on the brink: habitat requirements for declining populations of the marsh fritillary (Euphydryas aurinia) in SW England. In  (Ed) Lepidoptera Conservation in a Changing World, Springer Netherlands, 189-199.
Baxter S, McMillan O, Chamberlain N, ffrench-Constant R, Jiggins C (2009). Prospects for Locating Adaptive Genes in Lepidopteran Genomes. In  (Ed) Molecular Biology and Genetics of the Lepidoptera.
ffrench-Constant R, Dowling A, Hares MC, Yang G, Waterfield N (2007). Photorhabdus: Genomics of a Pathogen and Symbiont. In Pallen MJ, Nelson KE, Preston GM (Eds.) Bacterial Pathogenomics, Washington D.C.: ASM Press, 419-439.
McCart C, ffrench‐Constant R (2007). The Costs of DDT Resistance in Drosophila and Implications for Resistance Management Strategies. In  (Ed) Pesticide Chemistry, 305-312.
Waterfield N, ffrench-Constant R, Dowling A (2006). Insecticidal bacterial effectors from symbionts of insect-killing nematodes. In  (Ed) Insect Symbiosis, Volume 2, 211-224.
ffrench-Constant RH, Waterfield N, Daborn P (2005). 5.8 Insecticidal Toxins from Photorhabdus and Xenorhabdus. In  (Ed) Comprehensive Molecular Insect Science, 239-253.
ffrench-Constant RH (1993). Cloning of a putative GABAA receptor from cyclodiene-resistant Drosophila: a case study in the use of insecticide-resistant mutants to isolate neuroreceptors. In  (Ed) Comparative Molecular Neurobiology, 210-223.
ffrench-Constant RH, Roush RT, Cariño FA (1993). Drosophila as a Tool for Investigating the Molecular Genetics of Insecticide Resistance. In  (Ed) Molecular Approaches to Fundamental and Applied Entomology, 1-37.
Ffrench-Constant RH, Roush RT (1992). Cloning of an Invertebrate GABA Receptor from the Cyclodiene Resistance Locus in Drosophila. In  (Ed) Neurotox ’91, 285-292.
ffrench-Constant RH, Roush RT, MacIntyre RJ (1990). Isolation, Characterization and Progress in Cloning of Cyclodiene Insecticide Resistance in Drosophila melanogaster. In  (Ed) Molecular Insect Science, 41-48.
ffrench-Constant RH, Roush RT (1990). Resistance Detection and Documentation: the Relative Roles of Pesticidal and Biochemical Assays. In  (Ed) Pesticide Resistance in Arthropods, 4-38.

Conferences

McCart C, Ffrench-Constant RH (2008). Dissecting the insecticide-resistance- associated cytochrome P450 gene Cyp6g1.  Abstract.  Author URL.
Waterfield NR, Daborn PJ, Ffrench-Constant RH (2004). Insect pathogenicity islands in the insect pathogenic bacterium Photorhabdus.  Author URL.
Koch PB, Behnecke B, Weigmann-Lenz M, Ffrench-Constant RH (2000). Insect pigmentation: activities of beta-alanyldopamine synthase in wing color patterns of wild-type and melanic mutant swallowtail butterfly Papilio glaucus.  Abstract.  Author URL.
ffrench-Constant RH (1999). Insecticide resistance and nucleotide variability in the coffee berry borer.  Author URL.
ffrench-Constant RH, Pittendrigh B, Vaughan A, Anthony N (1999). Why are there so few insecticide resistance-associated mutations?.  Author URL.
ffrench-Constant RH, Pittendrigh B, Vaughan A, Anthony N (1998). Why are there so few resistance-associated mutations in insecticide target genes?.  Abstract.  Author URL.
Brun LO, Ffrench-Constant RH, CAFE ASCIINT (1997). Insecticide resistance in the coffee berry borer: State of current knowledge.  Author URL.
Breilid H, Brun LO, Andreev D, Ffrench-Constant RH, Kirkendall LR, CAFE ASCIINT (1997). Phylogeographic patterns of introduced populations of the coffee berry borer Hypothenemus hampei (Ferrari) (Coleoptera : Scolytidae) inferred from mitochondrial DNA sequences.  Author URL.
Ffrench-Constant RH, Devonshire AL (1986). Effect of different insecticides on the selection and control of highly resistant Myzus persicae.

Publications by year


In Press

ffrench-Constant R (In Press). Hybrid effects in field populations of the African Monarch Danaus chrysippus. Biological Journal of the Linnean Society
Yvon-Durocher G, Padfield D, Buckling A, Lowe C, Ffrench-Constant R, Schaum E (In Press). Metabolic compensation constrains the temperature dependence of gross primary production. Ecology Letters
Rhodes M, Bennie J, Spalding A, ffrench-Constant R, Maclean I (In Press). Recent advances in the remote sensing of insects. Biological Reviews
Padfield D, Lowe C, Buckling A, Ffrench-Constant R, Schaum E, Jennings S, Shelley F, Ólafsson JS, Yvon-Durocher G (In Press). Thermal adaptation constrains the temperature dependence of ecosystem metabolism.  Abstract.

2022

Mowbray S, Bennie J, Rhodes MW, Smith DAS, ffrench-Constant RH (2022). Back to the Meadow Brown: eyespot variation and field temperature in a classic butterfly polymorphism.
Kim K-W, De-Kayne R, Gordon IJ, Omufwoko KS, Martins DJ, Ffrench-Constant R, Martin SH (2022). Stepwise evolution of a butterfly supergene via duplication and inversion. Philos Trans R Soc Lond B Biol Sci, 377(1856). Abstract.  Author URL.

2021

Grant C (2021). Combating insecticide resistance in the tomato leafminer, Tuta absoluta.  Abstract.
McLeman A (2021). Developing screening tools to identify novel, resistance breaking pesticides.  Abstract.
Singh KS, De-Kayne R, Omufwoko KS, Martins DJ, Bass C, ffrench-Constant R, Martin SH (2021). Genome assembly of Danaus chrysippus and comparison with the Monarch Danaus plexippus. G3: Genes, Genomes, Genetics, 12(3).
Singh KS, De-Kayne R, Omufwoko KS, Martins DJ, Bass C, ffrench-Constant R, Martin SH (2021). Genome assembly of Danaus chrysippus and comparison with the Monarch Danaus plexippus.
Singh KS, Cordeiro EMG, Troczka BJ, Pym A, Mackisack J, Mathers TC, Duarte A, Legeai F, Robin S, Bielza P, et al (2021). Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae. Commun Biol, 4(1). Abstract.  Author URL.
Kim K-W, De-Kayne R, Gordon IJ, Omufwoko KS, Martins DJ, ffrench-Constant R, Martin SH (2021). Stepwise evolution of a butterfly supergene via duplication and inversion.

2020

Singh KS, Hosken DJ, Wedell N, Ffrench-Constant R, Bass C, Baxter S, Paszkiewicz K, Sharma MD (2020). De Novo Genome Assembly of the Meadow Brown Butterfly, Maniola jurtina. G3 (Bethesda), 10(5), 1477-1484. Abstract.  Author URL.
McLeman A, Troczka BJ, Homem RA, Duarte A, Zimmer C, Garrood WT, Pym A, Beadle K, Reid RJ, Douris V, et al (2020). Fly-Tox: a panel of transgenic flies expressing pest and pollinator cytochrome P450s. Pesticide Biochemistry and Physiology, 169 Abstract.
ffrench-Constant R, Martin S, Bass C, Singh K, Traut W, Gordon I, Smith D, Martins D (2020). Whole-chromosome hitchhiking driven by a male-killing endosymbiont. PLoS Biology

2019

Smith DAS, Traut W, Martin SH, Ireri P, Omufwoko KS, ffrench-Constant R, Gordon IJ (2019). Neo Sex Chromosomes, Colour Polymorphism and Male-Killing in the African Queen Butterfly, Danaus chrysippus (L.). Insects, 10(9), 291-291. Abstract.
Spalding A, Shanks K, Bennie J, Potter U, Ffrench-Constant R (2019). Optical Modelling and Phylogenetic Analysis Provide Clues to the Likely Function of Corneal Nipple Arrays in Butterflies and Moths. Insects, 10(9). Abstract.  Author URL.
Grant C, Jacobson R, Ilias A, Berger M, Vasakis E, Bielza P, Zimmer CT, Williamson MS, Ffrench-Constant RH, Vontas J, et al (2019). The evolution of multiple-insecticide resistance in UK populations of tomato leafminer, Tuta absoluta. Pest Manag Sci, 75(8), 2079-2085. Abstract.  Author URL.
Manktelow J (2019). Virulence and Evolutionary Ecology in the Entomopathogen Bacillus thuringiensis.  Abstract.
Martin SH, Singh KS, Gordon IJ, Omufwoko KS, Collins S, Warren IA, Munby H, Brattström O, Traut W, Martins DJ, et al (2019). Whole-chromosome hitchhiking driven by a male-killing endosymbiont.

2018

ffrench-Constant RH (2018). Introductory Chapter: Butterfly Wing Patterns: Not Just Painting by Numbers. In  (Ed) Butterfly Wing Patterns and Mimicry, ix-xiii.
Traut W, Ahola V, Smith DAS, Gordon IJ, Ffrench-Constant RH (2018). Karyotypes versus Genomes: the Nymphalid Butterflies Melitaea cinxia, Danaus plexippus, and D. chrysippus. Cytogenetic and Genome Research, 153(1), 46-53. Abstract.
Schaum CE, Student Research Team, Ffrench-Constant R, Lowe C, Ólafsson JS, Padfield D, Yvon-Durocher G (2018). Temperature-driven selection on metabolic traits increases the strength of an algal-grazer interaction in naturally warmed streams. Glob Chang Biol, 24(4), 1793-1803. Abstract.  Author URL.

2017

ffrench-Constant RH, Bass C (2017). Does resistance really carry a fitness cost?. Current Opinion in Insect Science, 21, 39-46. Abstract.
ffrench-Constant R, Waterfield N, Daborn P (2017). Insecticidal Toxins from Photorhabdus and Xenorhabdus ☆. In  (Ed) Reference Module in Life Sciences, 704-715.
Schaum C-E, ffrench-Constant R, Lowe C, Ólafsson JS, Padfield D, Yvon-Durocher G (2017). Temperature-driven selection on metabolic traits increases the strength of an algal-grazer interaction in naturally warmed streams.

2016

Smith DAS, Gordon IJ, Traut W, Herren J, Collins S, Martins DJ, Saitoti K, Ireri P, Ffrench-Constant R (2016). A neo-W chromosome in a tropical butterfly links colour pattern, male-killing, and speciation. Proceedings of the Royal Society B: Biological Sciences, 283(1835). Abstract.
Ffrench-Constant RH (2016). Butterfly gene flow goes berserk. Genome Biology, 17(1).
Ffrench-Constant RH, Williamson MS, Davies TGE, Bass C (2016). Ion channels as insecticide targets. J Neurogenet, 30(3-4), 163-177. Abstract.  Author URL.
Ffrench-Constant RH, Somers-Yeates R, Bennie J, Economou T, Hodgson D, Spalding A, McGregor PK (2016). Light pollution is associated with earlier tree budburst across the United Kingdom. Proceedings of the Royal Society of London. Series B
Nadeau NJ, Pardo-Diaz C, Whibley A, Supple MA, Saenko SV, Wallbank RWR, Wu GC, Maroja L, Ferguson L, Hanly JJ, et al (2016). The gene cortex controls mimicry and crypsis in butterflies and moths. Nature, 534(7605), 106-110. Abstract.  Author URL.

2015

Mulley G, Beeton ML, Wilkinson P, Vlisidou I, Ockendon-Powell N, Hapeshi A, Tobias NJ, Nollmann FI, Bode HB, van den Elsen J, et al (2015). From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity. PLOS ONE, 10(12), e0144937-e0144937.
Ffrench-Constant RH (2015). Insect Molecular Genetics: an Introduction to Principles and Applications. Third Edition. By Marjorie A. Hoy. Academic Press. Amsterdam (The Netherlands) and Boston (Massachusetts): Elsevier. $99.95. xxvii + 808 p.; ill.; index. ISBN: 978-0-12-415874-0. 2013. The Quarterly Review of Biology, 90(1), 98-98.
Nadeau NJ, Pardo-Diaz C, Whibley A, Supple M, Wallbank R, Wu GC, Maroja L, Ferguson L, Hines H, Salazar C, et al (2015). The origins of a novel butterfly wing patterning gene from within a family of conserved cell cycle regulators.
Pauchet Y, Wielsch N, Wilkinson PA, Sakaluk SK, Svatoš A, ffrench-Constant RH, Hunt J, Heckel DG (2015). What's in the Gift? Towards a Molecular Dissection of Nuptial Feeding in a Cricket. PLoS One, 10(10). Abstract.  Author URL.
Ffrench-Constant RH (2015). White butterflies as solar photovoltaic concentrators. Scientific Reports, 5

2014

Proschak A, Zhou Q, Schöner T, Thanwisai A, Kresovic D, Dowling A, ffrench-Constant R, Proschak E, Bode HB (2014). Biosynthesis of the Insecticidal Xenocyloins in<i>Xenorhabdus bovienii</i>. ChemBioChem, 15(3), 369-372.
ffrench-Constant RH, Dowling AJ (2014). Chapter Seven Photorhabdus Toxins. In  (Ed) Insect Midgut and Insecticidal Proteins, 343-388.
Timmermans MJTN, Baxter SW, Clark R, Heckel DG, Vogel H, Collins S, Papanicolaou A, Fukova I, Joron M, Thompson MJ, et al (2014). Comparative genomics of the mimicry switch in<i>Papilio dardanus</i>. Proceedings of the Royal Society B: Biological Sciences, 281(1787), 20140465-20140465. Abstract.
Ffrench-constant R, Valencia A, Eyun SI, Wang H, Pauchet Y, Benson AK (2014). Correction: Molecular evolution of glycoside hydrolase genes in the western corn rootworm (Diabrotica virgifera virgifera) (PLoS ONE (2014) 9, 4 (e94052) DOI: 10.1371/journal.pone.0094052). PLoS ONE, 9(7).
Ffrench-Constant RH (2014). GENOMICS of monarchs and migration. NATURE, 514(7522), 314-315. Author URL.
Kirsch R, Gramzow L, Theißen G, Siegfried BD, ffrench-Constant RH, Heckel DG, Pauchet Y (2014). Horizontal gene transfer and functional diversification of plant cell wall degrading polygalacturonases: Key events in the evolution of herbivory in beetles. Insect Biochemistry and Molecular Biology, 52, 33-50.
ffrench-Constant RH (2014). Insecticide resistance comes of age. Genome Biology, 15(2), 106-106.
Eyun SI, Wang H, Pauchet Y, Ffrench-Constant RH, Benson AK, Valencia-Jiménez A, Moriyama EN, Siegfried BD (2014). Molecular evolution of glycoside hydrolase genes in the western corn rootworm (Diabrotica virgifera virgifera). PLoS ONE, 9(4). Abstract.
Ffrench-Constant RH (2014). Of monarchs and migration. Nature, 514(7522), 314-315.
Ffrench-Constant RH, Dowling AJ (2014). Photorhabdus Toxins. INSECT MIDGUT AND INSECTICIDAL PROTEINS, 47, 343-388. Author URL.
ffrench-Constant RH (2014). Sex, butterflies and molecular biology: when pigmentation met mimicry. Pigment Cell & Melanoma Research, 27(4), 507-508.

2013

Swevers L, Huvenne H, Menschaert G, Kontogiannatos D, Kourti A, Pauchet Y, ffrench-Constant R, Smagghe G (2013). Colorado potato beetle (Coleoptera) gut transcriptome analysis: expression of RNA interference-related genes. Insect Molecular Biology, 22(6), 668-684.
Chauhan R, Jones R, Wilkinson P, Pauchet Y, Ffrench-Constant RH (2013). Cytochrome P450-encoding genes from the Heliconius genome as candidates for cyanogenesis. Insect Molecular Biology, 22(5), 532-540. Abstract.
Chauhan R, Jones R, Wilkinson P, Pauchet Y, Ffrench-Constant RH (2013). Cytochrome P450-encoding genes from the Heliconius genome as candidates for cyanogenesis. Insect Mol Biol, 22(5), 532-540. Abstract.  Author URL.
Smee MR, Pauchet Y, Wilkinson P, Wee B, Singer MC, ffrench-Constant RH, Hodgson DJ, Mikheyev AS (2013). Microsatellites for the marsh fritillary butterfly: de novo transcriptome sequencing, and a comparison with amplified fragment length polymorphism (AFLP) markers. PLoS One, 8(1). Abstract.  Author URL.
Reimer D, Cowles KN, Proschak A, Nollmann FI, Dowling AJ, Kaiser M, Constant RF, Goodrich-Blair H, Bode HB (2013). Rhabdopeptides as insect-specific virulence factors from entomopathogenic bacteria. ChemBioChem
Somers-Yeates R, Hodgson D, McGregor PK, Spalding A, Ffrench-Constant RH (2013). Shedding light on moths: shorter wavelengths attract noctuids more than geometrids. Biol Lett, 9(4). Abstract.  Author URL.
ffrench-Constant RH (2013). The Molecular Genetics of Insecticide Resistance. Genetics, 194(4), 807-815. Abstract.
Ferreira PG, Patalano S, Chauhan R, Ffrench-Constant R, Gabaldón T, Guigó R, Sumner S (2013). Transcriptome analyses of primitively eusocial wasps reveal novel insights into the evolution of sociality and the origin of alternative phenotypes. Genome Biology, 14(2), R20-R20.
Jones RT, Poul YL, Whibley AC, Mérot C, ffrench-Constant RH, Joron M (2013). Wing Shape Variation Associated with Mimicry in Butterflies. Evolution, 67(8), 2323-2334. Abstract.

2012

Dasmahapatra KK, Walters JR, Briscoe AD, Davey JW, Whibley A, Nadeau NJ, Zimin AV, Salazar C, Ferguson LC, Martin SH, et al (2012). Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. Nature, 487(7405), 94-98. Abstract.
Dasmahapatra KK, Walters JR, Briscoe AD, Davey JW, Whibley A, Nadeau NJ, Zimin AV, Hughes DST, Ferguson LC, Martin SH, et al (2012). Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. Nature
ffrench-Constant RH (2012). Butterfly wing colours and patterning by numbers. Heredity, 108(6), 592-593.
Jones RT, Salazar PA, ffrench-Constant RH, Jiggins CD, Joron M (2012). Evolution of a mimicry supergene from a multilocus architecture. Proc Biol Sci, 279(1727), 316-325. Abstract.  Author URL.
Nadeau NJ, Whibley A, Jones RT, Davey JW, Dasmahapatra KK, Baxter SW, Quail MA, Joron M, Ffrench-Constant RH, Blaxter ML, et al (2012). Genomic islands of divergence in hybridizing Heliconius butterflies identified by large-scale targeted sequencing. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 367(1587), 343-353. Author URL.
Grundmann F, Dill V, Dowling A, Thanwisai A, Bode E, Chantratita N, ffrench-Constant R, Bode HB (2012). Identification and isolation of insecticidal oxazoles from <i>Pseudomonas</i> spp. Beilstein Journal of Organic Chemistry, 8, 749-752. Abstract.
Karatolos N, Williamson MS, Denholm I, Gorman K, ffrench-Constant RH, Bass C (2012). Over-expression of a cytochrome P450 is associated with resistance to pyriproxyfen in the greenhouse whitefly trialeurodes vaporariorum. PLoS ONE, 7(2). Abstract.
Yang G, Hernandez-Rodriguez CS, Beeton ML, Wilkinson P, Ffrench-Constant RH, Waterfield NR (2012). Pdl1 is a Putative Lipase that Enhances Photorhabdus Toxin Complex Secretion. PLOS PATHOGENS, 8(5). Author URL.
Karatolos N, Williamson MS, Denholm I, Gorman K, Ffrench-Constant R, Nauen R (2012). Resistance to spiromesifen in Trialeurodes vaporariorum is associated with a single amino acid replacement in its target enzyme acetyl-coenzyme a carboxylase. Insect Molecular Biology, 21(3), 327-334. Abstract.
Nollmann FI, Dowling A, Kaiser M, Deckmann K, Grösch S, ffrench-Constant R, Bode HB (2012). Synthesis of szentiamide, a depsipeptide from entomopathogenic <i>Xenorhabdus szentirmaii</i> with activity against <i>Plasmodium falciparum</i>. Beilstein Journal of Organic Chemistry, 8, 528-533. Abstract.
Zhou Q, Dowling A, Heide H, Wöhnert J, Brandt U, Baum J, ffrench-Constant R, Bode HB (2012). Xentrivalpeptides A–Q: Depsipeptide Diversification in <i>Xenorhabdus</i>. Journal of Natural Products, 75(10), 1717-1722.

2011

Felföldi G, Eleftherianos I, Ffrench-Constant RH, Venekei I (2011). A serine proteinase homologue, SPH-3, plays a central role in insect immunity. J Immunol, 186(8), 4828-4834. Abstract.  Author URL.
Smee M, Smyth W, Tunmore M, ffrench-Constant R, Hodgson D (2011). Butterflies on the brink: Habitat requirements for declining populations of the marsh fritillary (Euphydryas aurinia) in SW England. Journal of Insect Conservation, 15(1), 153-163. Abstract.
Smee M, Smyth W, Tunmore M, Ffrench-Constant R, Hodgson D (2011). Butterflies on the brink: habitat requirements for declining populations of the marsh fritillary (Euphydryas aurinia) in SW England. J INSECT CONSERV, 15(1-2), 153-163. Abstract.
Orth JHC, Schorch B, Boundy S, Ffrench-Constant R, Kubick S, Aktories K (2011). Cell-free synthesis and characterization of a novel cytotoxic pierisin-like protein from the cabbage butterfly Pieris rapae. Toxicon, 57(2), 199-207.
Orth JHC, Schorch B, Boundy S, Ffrench-Constant R, Kubick S, Aktories K (2011). Cell-free synthesis and characterization of a novel cytotoxic pierisin-like protein from the cabbage butterfly Pieris rapae. TOXICON, 57(2), 199-207. Author URL.
Joron M, Frezal L, Jones RT, Chamberlain NL, Lee SF, Haag CR, Whibley A, Becuwe M, Baxter SW, Ferguson L, et al (2011). Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry. NATURE, 477(7363), 203-U102. Author URL.
Proschak A, Schultz K, Herrmann J, Dowling AJ, Brachmann AO, ffrench-Constant R, Mueller R, Bode HB (2011). Cytotoxic Fatty Acid Amides from Xenorhabdus. CHEMBIOCHEM, 12(13), 2011-2015. Author URL.
Smith DT, Hosken DJ, Rostant WG, Yeo M, Griffin RM, Bretman A, Price TAR, Ffrench-Constant RH, Wedell N (2011). DDT resistance, epistasis and male fitness in flies. J Evol Biol, 24(6), 1351-1362. Abstract.  Author URL.
van Munster M, le Gleuher M, Pauchet Y, Augustin S, Courtin C, Amichot M, ffrench-Constant RH, Pauron D (2011). Molecular characterization of three genes encoding aminopeptidases N in the poplar leaf beetle Chrysomela tremulae. Insect Molecular Biology, 20(2), 267-278.
Karatolos N, Pauchet Y, Wilkinson P, Chauhan R, Denholm I, Gorman K, Nelson DR, Bass C, ffrench-Constant RH, Williamson MS, et al (2011). Pyrosequencing the transcriptome of the greenhouse whitefly, Trialeurodes vaporariorum reveals multiple transcripts encoding insecticide targets and detoxifying enzymes. BMC Genomics, 12 Abstract.
Terenius O, Papanicolaou A, Garbutt JS, Eleftherianos I, Huvenne H, Kanginakudru S, Albrechtsen M, an C, Aymeric J-L, Barthel A, et al (2011). RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. JOURNAL OF INSECT PHYSIOLOGY, 57(2), 231-245. Author URL.

2010

Peat SM, ffrench-Constant RH, Waterfield NR, Marokházi J, Fodor A, Adams BJ (2010). A robust phylogenetic framework for the bacterial genus Photorhabdus and its use in studying the evolution and maintenance of bioluminescence: a case for 16S, gyrB, and glnA. Molecular Phylogenetics and Evolution, 57(2), 728-740.
Smee M, Smyth W, Tunmore M, ffrench-Constant R, Hodgson D (2010). Butterflies on the brink: habitat requirements for declining populations of the marsh fritillary (Euphydryas aurinia) in SW England. In  (Ed) Lepidoptera Conservation in a Changing World, Springer Netherlands, 189-199.
Ferguson L, Lee SF, Chamberlain N, Nadeau N, Joron M, Baxter S, Wilkinson P, Papanicolaou A, Kumar S, Kee T-J, et al (2010). Characterization of a hotspot for mimicry: assembly of a butterfly wing transcriptome to genomic sequence at the HmYb/Sb locus. Mol Ecol, 19 Suppl 1, 240-254. Abstract.  Author URL.
Eleftherianos I, Ffrench-Constant RH, Clarke DJ, Dowling AJ, Reynolds SE (2010). Dissecting the immune response to the entomopathogen Photorhabdus. TRENDS IN MICROBIOLOGY, 18(12), 552-560. Author URL.
Pauchet Y, Wilkinson P, Chauhan R, Ffrench-Constant RH (2010). Diversity of beetle genes encoding novel plant cell wall degrading enzymes. PLoS ONE, 5(12). Abstract.
Dowling AJ, Wilkinson PA, Holden MTG, Quail MA, Bentley SD, Reger J, Waterfield NR, Titball RW, Ffrench-Constant RH (2010). Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen Burkholderia pseudomallei K96243. PLoS One, 5(12). Abstract.  Author URL.
Counterman BA, Araujo-Perez F, Hines HM, Baxter SW, Morrison CM, Lindstrom DP, Papa R, Ferguson L, Joron M, Ffrench-Constant RH, et al (2010). Genomic Hotspots for Adaptation: the Population Genetics of Mullerian Mimicry in Heliconius erato. PLOS GENETICS, 6(2). Author URL.
Counterman BA, Araujo-Perez F, Hines HM, Baxter SW, Morrison CM, Lindstrom DP, Papa R, Ferguson L, Joron M, Ffrench-Constant RH, et al (2010). Genomic hotspots for adaptation: the population genetics of Müllerian mimicry in Heliconius erato. PLoS Genet, 6(2). Abstract.  Author URL.
Baxter SW, Nadeau NJ, Maroja LS, Wilkinson P, Counterman BA, Dawson A, Beltran M, Perez-Espona S, Chamberlain N, Ferguson L, et al (2010). Genomic hotspots for adaptation: the population genetics of Müllerian mimicry in the Heliconius melpomene clade. PLoS Genet, 6(2). Abstract.  Author URL.
Jones RT, Bakker SE, Stone D, Shuttleworth SN, Boundy S, McCart C, Daborn PJ, Ffrench-Constant RH, van den Elsen JMH (2010). Homology modelling of Drosophila cytochrome P450 enzymes associated with insecticide resistance. PEST MANAGEMENT SCIENCE, 66(10), 1106-1115. Author URL.
Jones RT, Bakker SE, Stone D, Shuttleworth SN, Boundy S, McCart C, Daborn PJ, ffrench-Constant RH, van den Elsen JMH (2010). Homology modelling of Drosophila cytochrome P450 enzymes associated with insecticide resistance. Pest Manag Sci, 66(10), 1106-1115. Abstract.  Author URL.
Wilkinson P, Paszkiewicz K, Moorhouse A, Szubert JM, Beatson S, Gerrard J, Waterfield NR, Ffrench-Constant RH (2010). New plasmids and putative virulence factors from the draft genome of an Australian clinical isolate of Photorhabdus asymbiotica. FEMS Microbiol Lett, 309(2), 136-143. Abstract.  Author URL.
Jones RT, Sanchez-Contreras M, Vlisidou I, Amos MR, Yang G, Munoz-Berbel X, Upadhyay A, Potter UJ, Joyce SA, Ciche TA, et al (2010). Photorhabdus adhesion modification protein (Pam) binds extracellular polysaccharide and alters bacterial attachment. BMC MICROBIOLOGY, 10 Author URL.
Jones RT, Sanchez-Contreras M, Vlisidou I, Amos MR, Yang G, Muñoz-Berbel X, Upadhyay A, Potter UJ, Joyce SA, Ciche TA, et al (2010). Photorhabdus adhesion modification protein (Pam) binds extracellular polysaccharide and alters bacterial attachment. BMC Microbiol, 10 Abstract.  Author URL.
Eleftherianos I, Joyce S, Ffrench-Constant RH, Clarke DJ, Reynolds SE (2010). Probing the tri-trophic interaction between insects, nematodes and Photorhabdus. Parasitology, 137(11), 1695-1706. Abstract.  Author URL.
Pauchet Y, Wilkinson P, Vogel H, Nelson DR, Reynolds SE, Heckel DG, ffrench-Constant RH (2010). Pyrosequencing the Manduca sexta larval midgut transcriptome: messages for digestion, detoxification and defence. Insect Mol Biol, 19(1), 61-75. Abstract.  Author URL.
Metcalfe K, Ffrench-Constant R, Gordon I (2010). Sacred sites as hotspots for biodiversity: the Three Sisters Cave complex in coastal Kenya. ORYX, 44(1), 118-123. Abstract.
Vlisidou I, Eleftherianos I, Dorus S, Yang G, ffrench-Constant RH, Reynolds SE, Waterfield NR (2010). The KdpD/KdpE two-component system of Photorhabdus asymbiotica promotes bacterial survival within M. sexta hemocytes. J Invertebr Pathol, 105(3), 352-362. Abstract.  Author URL.

2009

Eleftherianos I, Waterfield NR, Bone P, Boundy S, ffrench-Constant RH, Reynolds SE (2009). A single locus from the entomopathogenic bacterium Photorhabdus luminescens inhibits activated Manduca sexta phenoloxidase. FEMS Microbiol Lett, 293(2), 170-176. Abstract.  Author URL.
Wilkinson P, Waterfield NR, Crossman L, Corton C, Sanchez-Contreras M, Vlisidou I, Barron A, Bignell A, Clark L, Ormond D, et al (2009). Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens. BMC Genomics, 10 Abstract.  Author URL.
Vlisidou I, Dowling AJ, Evans IR, Waterfield N, ffrench-Constant RH, Wood W (2009). Drosophila embryos as model systems for monitoring bacterial infection in real time. PLoS Pathog, 5(7). Abstract.  Author URL.
Eleftherianos I, Felföldi G, ffrench-Constant RH, Reynolds SE (2009). Induced nitric oxide synthesis in the gut of<i>Manduca sexta</i>protects against oral infection by the bacterial pathogen<i>Photorhabdus luminescens</i>. Insect Molecular Biology, 18(4), 507-516.
Papanicolaou A, Stierli R, Ffrench-Constant RH, Heckel DG (2009). Next generation transcriptomes for next generation genomes using est2assembly. BMC Bioinformatics, 10 Abstract.  Author URL.
Ahantarig A, Chantawat N, Waterfield NR, ffrench-Constant R, Kittayapong P (2009). PirAB toxin from Photorhabdus asymbiotica as a larvicide against dengue vectors. Appl Environ Microbiol, 75(13), 4627-4629. Abstract.  Author URL.
Eleftherianos I, Xu M, Yadi H, Ffrench-Constant RH, Reynolds SE (2009). Plasmatocyte-spreading peptide (PSP) plays a central role in insect cellular immune defenses against bacterial infection. J Exp Biol, 212(Pt 12), 1840-1848. Abstract.  Author URL.
Baxter S, McMillan O, Chamberlain N, ffrench-Constant R, Jiggins C (2009). Prospects for Locating Adaptive Genes in Lepidopteran Genomes. In  (Ed) Molecular Biology and Genetics of the Lepidoptera.
Pauchet Y, Wilkinson P, van Munster M, Augustin S, Pauron D, ffrench-Constant RH (2009). Pyrosequencing of the midgut transcriptome of the poplar leaf beetle Chrysomela tremulae reveals new gene families in Coleoptera. Insect Biochem Mol Biol, 39(5-6), 403-413. Abstract.  Author URL.
Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Yang G, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, et al (2009). Rapid Virulence Annotation (RVA): Identification of virulence factors using a bacterial genome library and multiple invertebrate hosts (vol 105, pg 15967, 2008). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(6), 2083-2083. Author URL.
Smith DT, Hosken DJ, Ffrench-Constant RH, Wedell N (2009). Variation in sex peptide expression in D. melanogaster. Genet Res (Camb), 91(4), 237-242. Abstract.  Author URL.

2008

Zefania S, ffrench-Constant R, Long PR, Székely T (2008). Breeding distribution and ecology of the threatened Madagascar Plover. Charadrius thoracicus. Ostrich, 79(1), 43-51.
Baxter SW, Papa R, Chamberlain N, Humphray SJ, Joron M, Morrison C, ffrench-Constant RH, McMillan WO, Jiggins CD (2008). Convergent evolution in the genetic basis of Müllerian mimicry in heliconius butterflies. Genetics, 180(3), 1567-1577. Abstract.  Author URL.
Eleftherianos I, Baldwin H, ffrench-Constant RH, Reynolds SE (2008). Developmental modulation of immunity: changes within the feeding period of the fifth larval stage in the defence reactions of Manduca sexta to infection by Photorhabdus. J Insect Physiol, 54(1), 309-318. Abstract.  Author URL.
McCart C, Ffrench-Constant RH (2008). Dissecting the insecticide-resistance- associated cytochrome P450 gene Cyp6g1.  Abstract.  Author URL.
Long PR, Zefania S, Ffrench-Constant RH, Szekely T (2008). Estimating the population size of an endangered shorebird, the Madagascar plover, using a habitat suitability model. ANIMAL CONSERVATION, 11(2), 118-127. Author URL.
Papa R, Morrison CM, Walters JR, Counterman BA, Chen R, Halder G, Ferguson L, Chamberlain N, ffrench-Constant R, Kapan DD, et al (2008). Highly conserved gene order and numerous novel repetitive elements in genomic regions linked to wing pattern variation in Heliconius butterflies. BMC Genomics, 9(1), 345-345.
van Dijk RE, Komdeur J, van der Velde M, Szentirmai I, Yang X, Ffrench-Constant R, Székely T (2008). Offspring sex ratio in the sequentially polygamous Penduline Tit Remiz pendulinus. Journal of Ornithology, 149(4), 521-527.
Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Yang G, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, et al (2008). Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts. Proc Natl Acad Sci U S A, 105(41), 15967-15972. Abstract.  Author URL.
Lindsay HA, Baines R, ffrench-Constant R, Lilley K, Jacobs HT, O'Dell KMC (2008). The Dominant Cold-Sensitive Out-Cold Mutants of Drosophila melanogaster Have Novel Missense Mutations in the Voltage-Gated Sodium Channel Gene paralytic. GENETICS, 180(2), 873-884. Author URL.
Hares MC, Hinchliffe SJ, Strong PCR, Eleftherianos I, Dowling AJ, Ffrench-Constant RH, Waterfield N (2008). The Yersinia pseudotuberculosis and Yersinia pestis toxin complex is active against cultured mammalian cells. Microbiology (Reading), 154(Pt 11), 3503-3517. Abstract.  Author URL.

2007

Iatrou K, Pierre (2007). 7<sup>th</sup>International Workshop on the Molecular Biology and Genetics of the Lepidoptera. Journal of Insect Science, 7(29), 1-5.
McCart, C. Woods, D.J. Terhzaz, S. (2007). A Drosophila systems approach to xenobiotic metabolism. Physiological Genomics, 30, 223-231.
Ffrench-Constant RH, Eleftherianos I, Reynolds SE (2007). A nematode symbiont sheds light on invertebrate immunity. Trends Parasitol, 23(11), 514-517. Abstract.  Author URL.
Sayed A, Nekl ER, Siqueira HAA, Wang H-C, Ffrench-Constant RH, Bagley M, Siegfried BD (2007). A novel cadherin-like gene from western corn rootworm, Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae), larval midgut tissue. Insect Mol Biol, 16(5), 591-600. Abstract.  Author URL.
Erickson DL, Waterfield NR, Vadyvaloo V, Long D, Fischer ER, ffrench-Constant R, Hinnebusch BJ (2007). Acute oral toxicity of Yersinia pseudotuberculosis to fleas: implications for the evolution of vector-borne transmission of plague. CELLULAR MICROBIOLOGY, 9(11), 2658-2666. Author URL.
Boundy, S. Joyce, S. Aslam, S. (2007). An antibiotic produced by an insect-pathogenic bacterium suppresses host defences through phenoloxidase inhibition. Proceedings of the National Academy of Sciences USA, 104, 2419-2424.
Bogwitz, M.R. McCart, C. Andrianopoulos, A. (2007). Cis-regulatory elements of the Accord retrotransposon result in tissue-specific expression of the Drosophila melanogaster insecticide resistance gene Cyp6g1. Genetics, 175, 1071-1077.
Chamberlain N, Baxter S, Jiggins C, Ffrench-Constant RH (2007). Dissecting butterfly wing pattern formation in Batesian and Mullerian mimicry. JOURNAL OF INSECT SCIENCE, 7 Author URL.
Lumb, C. Boey, A. Wong, W. (2007). Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression. Insect Biochemistry and Molecular Biology, 37, 512-519.
Baxter SW, Chamberlain N, Papa R, Humphray SJ, Ffrench-Constant RH, McMillan WO, Jiggins CD (2007). Identifying DNA markers close to quantitative traits in lepidopteran genomes: Using wing colour variation in Heliconius butterflies as a model. JOURNAL OF INSECT SCIENCE, 7 Author URL.
ffrench-Constant RH, Dowling A, Waterfield NR (2007). Insecticidal toxins from Photorhabdus bacteria and their potential use in agriculture. Toxicon, 49(4), 436-451. Abstract.  Author URL.
ffrench-Constant R, Dowling A, Hares MC, Yang G, Waterfield N (2007). Photorhabdus: Genomics of a Pathogen and Symbiont. In Pallen MJ, Nelson KE, Preston GM (Eds.) Bacterial Pathogenomics, Washington D.C.: ASM Press, 419-439.
Eleftherianos I, Millichap PJ, Felfoldi G, Gokcen F, Waterfield N, Clarke DJ, Ffrench-Constant RH, Reynolds SE (2007). Probing the insect immune system with the entomopathogen Photorhabdus. JOURNAL OF INSECT SCIENCE, 7 Author URL.
McCart C, ffrench‐Constant R (2007). The Costs of DDT Resistance in Drosophila and Implications for Resistance Management Strategies. In  (Ed) Pesticide Chemistry, 305-312.
Dowling AJ, Waterfield NR, Hares MC, Le Goff G, Streuli CH, ffrench-Constant RH (2007). The Mcf1 toxin induces apoptosis via the mitochondrial pathway and apoptosis is attenuated by mutation of the BH3-like domain. Cell Microbiol, 9(10), 2470-2484. Abstract.  Author URL.
Eleftherianos I, Gökçen F, Felföldi G, Millichap PJ, Trenczek TE, ffrench-Constant RH, Reynolds SE (2007). The immunoglobulin family protein Hemolin mediates cellular immune responses to bacteria in the insect Manduca sexta. Cell Microbiol, 9(5), 1137-1147. Abstract.  Author URL.
Waterfield N, Hares MC, Hinchliffe S, Wren B, ffrench-Constant R (2007). The insect Toxin complex of Yersinia. Ad Exp Med Biol, 603, 247-257.
Waterfield N, Hares M, Hinchliffe S, Wren B, ffrench-Constant R (2007). The insect toxin complex of Yersinia. Adv Exp Med Biol, 603, 247-257. Abstract.  Author URL.
Felfoldi G, Eleftherianos I, Ffrench-Constant RH, Venekei I, Reynolds SE (2007). The role of serineprotease homolgue 3 (SPH-3) in Manduca sexta shown by RNA interference. JOURNAL OF INSECT SCIENCE, 7 Author URL.
Ffrench-Constant RH (2007). Which came first: insecticides or resistance?. Trends Genet, 23(1), 1-4. Abstract.  Author URL.

2006

Ffrench-Constant RH, Chamberlain N, Joron M, Papa R (2006). A conserved supergene locus controls colour pattern diversity in Heliconus butterflies. PLoS Biology, 4(10), 1831-1840.
Ffrench-Constant R, Waterfield N (2006). An ABC guide to the bacterial toxin complexes. Adv Appl Microbiol, 58, 169-183. Author URL.
KÜPPER C, HORSBURGH GJ, DAWSON DA, FFRENCH-CONSTANT R, SZÉKELY T, BURKE T (2006). Characterization of 36 polymorphic microsatellite loci in the Kentish plover (Charadrius alexandrinus) including two sex-linked loci and their amplification in four other Charadrius species. Molecular Ecology Notes, 7(1), 35-39.
ffrench-Constant RH, Waterfield NR (2006). Ground control for insect pests. Nat Biotechnol, 24(6), 660-661. Author URL.
Waterfield N, ffrench-Constant R, Dowling A (2006). Insecticidal bacterial effectors from symbionts of insect-killing nematodes. In  (Ed) Insect Symbiosis, Volume 2, 211-224.
Jenkins ATA, Dash H-A, Boundy S, Halliwell CM, ffrench-Constant RH (2006). Methoxy-resorufin ether as an electrochemically active biological probe for cytochrome P450 O-demethylation. Bioelectrochemistry, 68(1), 67-71. Abstract.  Author URL.
Gerrard JG, Joyce SA, Clarke DJ, ffrench-Constant RH, Nimmo GR, Looke DFM, Feil EJ, Pearce L, Waterfield NR (2006). Nematode symbiont for Photorhabdus asymbiotica. Emerg Infect Dis, 12(10), 1562-1564. Abstract.  Author URL.
Yang G, Dowling AJ, Gerike U, ffrench-Constant RH, Waterfield NR (2006). Photorhabdus virulence cassettes confer injectable insecticidal activity against the wax moth. J Bacteriol, 188(6), 2254-2261. Abstract.  Author URL.
Eleftherianos I, Marokhazi J, Millichap PJ, Hodgkinson AJ, Sriboonlert A, ffrench-Constant RH, Reynolds SE (2006). Prior infection of Manduca sexta with non-pathogenic Escherichia coli elicits immunity to pathogenic Photorhabdus luminescens: roles of immune-related proteins shown by RNA interference. Insect Biochem Mol Biol, 36(6), 517-525. Abstract.  Author URL.
Eleftherianos I, Millichap PJ, ffrench-Constant RH, Reynolds SE (2006). RNAi suppression of recognition protein mediated immune responses in the tobacco hornworm Manduca sexta causes increased susceptibility to the insect pathogen Photorhabdus. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 30(12), 1099-1107. Author URL.
Eleftherianos I, Millichap PJ, ffrench-Constant RH, Reynolds SE (2006). RNAi suppression of recognition protein mediated immune responses in the tobacco hornworm Manduca sexta causes increased susceptibility to the insect pathogen Photorhabdus. Dev Comp Immunol, 30(12), 1099-1107. Abstract.  Author URL.
ffrench-Constant R, Daborn P, Feyereisen R (2006). Resistance and the jumping gene. Bioessays, 28(1), 6-8. Abstract.  Author URL.
Le Goff G, Hilliou F, Siegfried BD, Boundy S, Wajnberg E, Sofer L, Audant P, Ffrench-Constant RH, Feyereisen R (2006). Xenobiotic response in Drosophila melanogaster: Sex dependence of P450 and GST gene induction. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 36(8), 674-682. Author URL.
Le Goff G, Hilliou F, Siegfried BD, Boundy S, Wajnberg E, Sofer L, Audant P, ffrench-Constant RH, Feyereisen R (2006). Xenobiotic response in Drosophila melanogaster: sex dependence of P450 and GST gene induction. Insect Biochem Mol Biol, 36(8), 674-682. Abstract.  Author URL.

2005

ffrench-Constant RH, Waterfield N, Daborn P (2005). 5.8 Insecticidal Toxins from Photorhabdus and Xenorhabdus. In  (Ed) Comprehensive Molecular Insect Science, 239-253.
Ffrench-Constant R, Waterfield N (2005). An ABC Guide to the Bacterial Toxin Complexes. Adv Appl Microbiol, 58C, 169-183. Author URL.
Buckling A, Neilson J, Lindsay J, ffrench-Constant R, Enright M, Day N, Massey RC (2005). Clonal distribution and phase-variable expression of a major histocompatibility complex analogue protein in Staphylococcus aureus. J Bacteriol, 187(8), 2917-2919. Abstract.  Author URL.
Buckling, A. McGhee, M. ffrench-constant, R.H. (2005). DDT resistance in flies carries no cost. Current Biology, 15(15), 587-589.
McCart C, Buckling A, Ffrench-Constant RH (2005). DDT resistance in flies carries no cost. Curr Biol, 15(15), R587-R589. Author URL.
Siegfried BD, Waterfield N, ffrench-Constant RH (2005). Expressed sequence tags from Diabrotica virgifera virgifera midgut identify a coleopteran cadherin and a diversity of cathepsins. INSECT MOLECULAR BIOLOGY, 14(2), 137-143. Author URL.
Siegfried BD, Waterfield N, ffrench-Constant RH (2005). Expressed sequence tags from Diabrotica virgifera virgifera midgut identify a coleopteran cadherin and a diversity of cathepsins. Insect Mol Biol, 14(2), 137-143. Abstract.  Author URL.
Eleftherianos I, ffrench-Constant RH, Reynolds SE (2005). Modulating lepidopteran immunity to bacteria using pre-infection and RNA interference. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 141(3), S109-S109. Author URL.
Waterfield N, Hares M, Yang G, Dowling A, ffrench-Constant R (2005). Potentiation and cellular phenotypes of the insecticidal Toxin complexes of Photorhabdus bacteria. Cell Microbiol, 7(3), 373-382. Abstract.  Author URL.
Ffrench-Constant RH (2005). Something old, something transgenic, or something fungal for mosquito control?. Trends Ecol Evol, 20(11), 577-579. Abstract.  Author URL.
Jenkins ATA, Buckling A, McGhee M, ffrench-Constant RH (2005). Surface plasmon resonance shows that type IV pili are important in surface attachment by Pseudomonas aeruginosa. J R Soc Interface, 2(3), 255-259. Abstract.  Author URL.
Waterfield N, Kamita SG, Hammock BD, ffrench-Constant R (2005). The Photorhabdus Pir toxins are similar to a developmentally regulated insect protein but show no juvenile hormone esterase activity. FEMS Microbiol Lett, 245(1), 47-52. Abstract.  Author URL.
NICE CC, ANTHONY N, GELEMBIUK G, RATERMAN D, FFRENCH-CONSTANT R (2005). The history and geography of diversification within the butterfly genus Lycaeides in North America. Molecular Ecology, 14(6), 1741-1754.

2004

Daborn P, McCart C, Woods D, ffrench-Constant RH (2004). Detection of insecticide resistance-associated mutations in cat flea Rdl by TaqMan-allele specific amplification. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 79(1), 25-30. Author URL.
Au C, Dean P, Reynolds SE, ffrench-Constant RH (2004). Effect of the insect pathogenic bacterium Photorhabdus on insect phagocytes. Cell Microbiol, 6(1), 89-95. Abstract.  Author URL.
Gerrard J, Waterfield N, Vohra R, ffrench-Constant R (2004). Human infection with Photorhabdus asymbiotica: an emerging bacterial pathogen. Microbes and Infection, 6(2), 229-237.
Waterfield NR, Daborn PJ, Ffrench-Constant RH (2004). Insect pathogenicity islands in the insect pathogenic bacterium Photorhabdus.  Author URL.
Massey RC, Buckling A, Ffrench-Constant R (2004). Interference competition and parasite virulence. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 271(1541), 785-788. Author URL.
Massey RC, Buckling A, ffrench-Constant R (2004). Interference competition and parasite virulence. Proc Biol Sci, 271(1541), 785-788. Abstract.  Author URL.
Waterfield NR, Wren BW, Ffrench-Constant RH (2004). Invertebrates as a source of emerging human pathogens. Nat Rev Microbiol, 2(10), 833-841. Abstract.  Author URL.
Anthony N, Gelembiuk G, Raterman D, Nice C, Ffrench-Constant R (2004). Isolation and Characterization of Microsatellite Markers from the Endangered Karner Blue Butterfly Lycaeides Melissa Samuelis (Lepidoptera). Hereditas, 134(3), 271-273.
Jenkins ATA, Ffrench-Constant R, Buckling A, Clarke DJ, Jarvis K (2004). Study of the attachment of Pseudomonas aeruginosa on gold and modified gold surfaces using surface plasmon resonance. BIOTECHNOLOGY PROGRESS, 20(4), 1233-1236. Author URL.
Jenkins ATA, ffrench-constant R, Buckling A, Clarke DJ, Jarvis K (2004). Study of the attachment of Pseudomonas aeruginosa on gold and modified gold surfaces using surface plasmon resonance. Biotechnol Prog, 20(4), 1233-1236. Abstract.  Author URL.
Ffrench-Constant RH, Daborn PJ, Le Goff G (2004). The genetics and genomics of insecticide resistance. Trends Genet, 20(3), 163-170. Abstract.  Author URL.
Ffrench-Constant RH, Daborn PJ, Dowling AJ, Steuli CH (2004). The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells. Cellular Microbiology, 6(4), 345-353.
Dowling AJ, Daborn PJ, Waterfield NR, Wang P, Streuli CH, ffrench-Constant RH (2004). The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells. CELLULAR MICROBIOLOGY, 6(4), 345-353. Author URL.
Catania, F. Kauer, M.O. (2004). World-wide survey of an Accord insertion and its association with DDT resistance in Drosophila Melanogaster. Molecular Ecology, 13(8), 2491-2504.

2003

Ffrench-Constant R, Waterfield N, Daborn P, Joyce S, Bennett H, Au C, Dowling A, Boundy S, Reynolds S, Clarke D, et al (2003). <i>Photorhabdus</i>: towards a functional genomic analysis of a symbiont and pathogen. FEMS Microbiology Reviews, 26(5), 433-456.
Bowen DJ, Rocheleau TA, Grutzmacher CK, Meslet L, Valens M, Marble D, Dowling A, Ffrench-Constant R, Blight MA (2003). Genetic and biochemical characterization of PrtA, an RTX-like metalloprotease from Photorhabdus. Microbiology (Reading), 149(Pt 6), 1581-1591. Abstract.  Author URL.
Le Goff G, Boundy S, Daborn PJ, Yen JL, Sofer L, Lind R, Sabourault C, Madi-Ravazzi L, ffrench-Constant RH (2003). Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila. Insect Biochem Mol Biol, 33(7), 701-708. Abstract.  Author URL.
ffrench-Constant R, Waterfield N, Daborn P, Joyce S, Bennett H, Au C, Dowling A, Boundy S, Reynolds S, Clarke D, et al (2003). Photorhabdus: towards a functional genomic analysis of a symbiont and pathogen. FEMS Microbiol Rev, 26(5), 433-456. Abstract.  Author URL.
DeCamillis M, ffrench-Constant R (2003). Proboscipedia represses distal signaling in the embryonic gnathal limb fields of Tribolium castaneum. Dev Genes Evol, 213(2), 55-64. Abstract.  Author URL.
Waterfield N, Daborn P, Dowling A, Yang G, Hares MC, ffrench-Constant R (2003). The insecticidal toxin Makes Caterpillars floppy 2 (Mcf2) shows similarity to HrmA, a virulence protein from a plant pathogen. Fems Microbiol Letts, 229, 265-270.
Waterfield NR, Daborn PJ, Dowling AJ, Yang G, Hares M, ffrench-Constant RH (2003). The insecticidal toxin makes caterpillars floppy 2 (Mcf2) shows similarity to HrmA, an avirulence protein from a plant pathogen. FEMS Microbiol Lett, 229(2), 265-270. Abstract.  Author URL.
Marokhazi J, Waterfield N, LeGoff G, Feil E, Stabler R, Hinds J, Fodor A, ffrench-Constant RH (2003). Using a DNA microarray to investigate the distribution of insect virulence factors in strains of photorhabdus bacteria. J Bacteriol, 185(15), 4648-4656. Abstract.  Author URL.

2002

Ffrench-Constant RH, Bogwitz M, Daborn PJ, Yen JL (2002). A single P450 allele associated with insecticide resistance in Drosophila. Science, 297(5590), 2253-2256.
Ffrench-Constant RH, Daborn PJ, Silva CP, Waterfield N (2002). A single Photorhabdus gene, makes caterpillars floppy (mfc), allows Escherichia coli to persist within and kill insects. Proceedings of the National Academy of Sciences, 99(16), 10742-10747.
Silva CP, Waterfield NR, Daborn PJ, Dean P, Chilver T, Au CPY, Sharma S, Potter U, Reynolds SE, ffrench-Constant RH, et al (2002). Bacterial infection of a model insect: Photorhabdus luminescens and Manduca sexta. Cell Microbiol, 4(6), 329-339. Abstract.  Author URL.
Waterfield NR, Daborn PJ, ffrench-Constant RH (2002). Genomic islands in Photorhabdus. Trends Microbiol, 10(12), 541-545. Abstract.  Author URL.
Andreasen MH, Ffrench-Constant RH (2002). In situ hybridization to the Rdl locus on polytene chromosome 3L of Anopheles stephensi. Med Vet Entomol, 16(4), 452-455. Abstract.  Author URL.
Nice CC, Fordyce JA, Shapiro AM, Ffrench-Constant R (2002). Lack of evidence for reproductive isolation among ecologically specialised lycaenid butterflies. Ecological Entomology, 27(6), 702-712.
Sharma S, Waterfield N, Bowen D, Rocheleau T, Holland L, James R, ffrench-Constant R (2002). The lumicins: novel bacteriocins from Photorhabdus luminescens with similarity to the uropathogenic-specific protein (USP) from uropathogenic Escherichia coli. FEMS MICROBIOLOGY LETTERS, 214(2), 241-249. Author URL.
Sharma S, Waterfield N, Bowen D, Rocheleau T, Holland L, James R, ffrench-Constant R (2002). The lumicins: novel bacteriocins from Photorhabdus luminescens with similarity to the uropathogenic-specific protein (USP) from uropathogenic Escherichia coli. FEMS Microbiol Lett, 214(2), 241-249. Abstract.  Author URL.

2001

Daborn P, Boundy S, Yen J, Pittendrigh B, ffrench-Constant R (2001). DDT resistance in Drosophila correlates with Cyp6g1 over-expression and confers cross-resistance to the neonicotinoid imidacloprid. Mol Genet Genomics, 266(4), 556-563. Abstract.  Author URL.
Daborn PJ, Waterfield N, Blight MA, Ffrench-Constant RH (2001). Measuring virulence factor expression by the pathogenic bacterium Photorhabdus luminescens in culture and during insect infection. J Bacteriol, 183(20), 5834-5839. Abstract.  Author URL.
Waterfield N, Dowling A, Sharma S, Daborn PJ, Potter U, Ffrench-Constant RH (2001). Oral toxicity of Photorhabdus luminescens W14 toxin complexes in Escherichia coli. Appl Environ Microbiol, 67(11), 5017-5024. Abstract.  Author URL.
Waterfield NR, Bowen DJ, Fetherston JD, Perry RD, ffrench-Constant RH (2001). The tc genes of Photorhabdus: a growing family. Trends Microbiol, 9(4), 185-191. Abstract.  Author URL.

2000

Ffrench-Constant RH, Waterfield N, Burland V, Perna NT, Daborn PJ, Bowen D, Blattner FR (2000). A genomic sample sequence of the entomopathogenic bacterium Photorhabdus luminescens W14: potential implications for virulence. Appl Environ Microbiol, 66(8), 3310-3329. Abstract.  Author URL.
Koch PB, Lorenz U, Brakefield PM, ffrench-Constant RH (2000). Butterfly wing pattern mutants: developmental heterochrony and co-ordinately regulated phenotypes. Dev Genes Evol, 210(11), 536-544. Abstract.  Author URL.
(2000). Cloning, sequencing and functional expression of an acetylcholinesterase gene from the yellow fever mosquito<i>Aedes aegypti</i>. FEBS Letters, 368(3), 461-465.
Ffrench-Constant RH, Anthony N, Aronstein K, Rocheleau T, Stilwell G (2000). Cyclodiene insecticide resistance: from molecular to population genetics. Annu Rev Entomol, 45, 449-466. Abstract.  Author URL.
Koch PB, Behnecke B, Weigmann-Lenz M, Ffrench-Constant RH (2000). Insect pigmentation: activities of beta-alanyldopamine synthase in wing color patterns of wild-type and melanic mutant swallowtail butterfly Papilio glaucus.  Abstract.  Author URL.
ffrench-Constant RH, Bowen DJ (2000). Novel insecticidal toxins from nematode-symbiotic bacteria. Cell Mol Life Sci, 57(5), 828-833. Abstract.  Author URL.
Martin RL, Pittendrigh B, Liu J, Reenan R, ffrench-Constant R, Hanck DA (2000). Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin. Insect Biochemistry and Molecular Biology, 30(11), 1051-1059.
Coustau C, Chevillon C, ffrench-Constant R (2000). Resistance to xenobiotics and parasites: can we count the cost?. Trends in Ecology & Evolution, 15(9), 378-383.
Bowen D, Blackburn M, Rocheleau T, Grutzmacher C, ffrench-Constant RH (2000). Secreted proteases from Photorhabdus luminescens: separation of the extracellular proteases from the insecticidal Tc toxin complexes. Insect Biochem Mol Biol, 30(1), 69-74. Abstract.  Author URL.
Koch PB, Behnecke B, ffrench-Constant RH (2000). The molecular basis of melanism and mimicry in a swallowtail butterfly. Curr Biol, 10(10), 591-594. Abstract.  Author URL.
Crennell SJ, Tickler PM, Bowen DJ, ffrench-Constant RH (2000). The predicted structure of photopexin from Photorhabdus shows the first haemopexin-like motif in prokaryotes. FEMS Microbiol Lett, 191(1), 139-144. Abstract.  Author URL.

1999

Wang CT, Zhang HG, Rocheleau TA, ffrench-Constant RH, Jackson MB (1999). Cation permeability and cation-anion interactions in a mutant GABA-gated chloride channel from Drosophila. Biophys J, 77(2), 691-700. Abstract.  Author URL.
Bowen D, Blackburn M, Rocheleau TA, Andreev O, Golubeva E, ffrench‐Constant RH (1999). Insecticidal toxins from the bacterium Photorhabdus luminescens: gene cloning and toxin histopathology. Pest Management Science, 55(6), 666-668.
ffrench-Constant RH (1999). Insecticide resistance and nucleotide variability in the coffee berry borer.  Author URL.
Andreev D, Kreitman M, Phillips TW, Beeman RW, ffrench-Constant RH (1999). Multiple origins of cyclodiene insecticide resistance in Tribolium castaneum (Coleoptera: Tenebrionidae). J Mol Evol, 48(5), 615-624. Abstract.  Author URL.
ffrench-Constant R, Bowen D (1999). Photorhabdus toxins: novel biological insecticides. Curr Opin Microbiol, 2(3), 284-288. Abstract.  Author URL.
ffrench-Constant RH (1999). Target site mediated insecticide resistance: what questions remain?. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 29(5), 397-403. Author URL.
ffrench-Constant RH, Pittendrigh B, Vaughan A, Anthony N (1999). Why are there so few insecticide resistance-associated mutations?.  Author URL.

1998

Blackburn M, Golubeva E, Bowen D, Ffrench-Constant RH (1998). A novel insecticidal toxin from photorhabdus luminescens, toxin complex a (Tca), and its histopathological effects on the midgut of manduca sexta. Appl Environ Microbiol, 64(8), 3036-3041. Abstract.  Author URL.
Liu HT, Stilwell G, Anthony N, Rocheleau T, ffrench-Constant RH (1998). Analysis of a mosquito acetylcholinesterase gene promoter. Insect Mol Biol, 7(1), 11-17. Abstract.  Author URL.
Vaughan A, Chadee DD, French-Constant R (1998). Biochemical monitoring of organophosphorus and carbamate insecticide resistance in Aedes aegypti mosquitoes from Trinidad. Med Vet Entomol, 12(3), 318-321. Author URL.
Anthony NM, Brown JK, Feyereisen R, ffrench-Constant RH (1998). Diagnosis and characterization of insecticide-insensitive acetylcholinesterase in three populations of the sweetpotato whitefly Bemisia tabaci. PESTICIDE SCIENCE, 52(1), 39-46. Author URL.
Anthony N, Unruh T, Ganser D, ffrench-Constant R (1998). Duplication of the Rdl GABA receptor subunit gene in an insecticide-resistant aphid, Myzus persicae. Mol Gen Genet, 260(2-3), 165-175. Abstract.  Author URL.
Bowen D, Rocheleau TA, Blackburn M, Andreev O, Golubeva E, Bhartia R, ffrench-Constant RH (1998). Insecticidal toxins from the bacterium Photorhabdus luminescens. Science, 280(5372), 2129-2132. Abstract.  Author URL.
Andreev D, Breilid H, Kirkendall L, Brun LO, ffrench-Constant RH (1998). Lack of nucleotide variability in a beetle pest with extreme inbreeding. Insect Mol Biol, 7(2), 197-200. Abstract.  Author URL.
Koch PB, Keys DN, Rocheleau T, Aronstein K, Blackburn M, Carroll SB, ffrench-Constant RH (1998). Regulation of dopa decarboxylase expression during colour pattern formation in wild-type and melanic tiger swallowtail butterflies. Development, 125(12), 2303-2313. Abstract.  Author URL.
Stilwell GE, ffrench-Constant RH (1998). Transcriptional analysis of the Drosophila GABA receptor gene resistance to dieldrin. J Neurobiol, 36(4), 468-484. Abstract.  Author URL.
ffrench-Constant RH, Pittendrigh B, Vaughan A, Anthony N (1998). Why are there so few resistance-associated mutations in insecticide target genes?.  Abstract.  Author URL.

1997

Pittendrigh B, Aronstein K, Zinkovsky E, Andreev O, Campbell B, Daly J, Trowell S, Ffrench-Constant RH (1997). Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain. Insect Biochem Mol Biol, 27(6), 507-512. Abstract.  Author URL.
Brun LO, Ffrench-Constant RH, CAFE ASCIINT (1997). Insecticide resistance in the coffee berry borer: State of current knowledge.  Author URL.
Hosie AM, Aronstein K, Sattelle DB, ffrench-Constant RH (1997). Molecular biology of insect neuronal GABA receptors. Trends Neurosci, 20(12), 578-583. Abstract.  Author URL.
Severson DW, Anthony NM, Andreev O, ffrench-Constant RH (1997). Molecular mapping of insecticide resistance genes in the yellow fever mosquito (Aedes aegypti). J Hered, 88(6), 520-524. Abstract.  Author URL.
Breilid H, Brun LO, Andreev D, Ffrench-Constant RH, Kirkendall LR, CAFE ASCIINT (1997). Phylogeographic patterns of introduced populations of the coffee berry borer Hypothenemus hampei (Ferrari) (Coleoptera : Scolytidae) inferred from mitochondrial DNA sequences.  Author URL.
Pittendrigh B, Reenan R, ffrench-Constant RH, Ganetzky B (1997). Point mutations in the Drosophila sodium channel gene para associated with resistance to DDT and pyrethroid insecticides. Mol Gen Genet, 256(6), 602-610. Abstract.  Author URL.
Vaughan A, Rocheleau T, ffrench-Constant R (1997). Site-directed mutagenesis of an acetylcholinesterase gene from the yellow fever mosquito Aedes aegypti confers insecticide insensitivity. Exp Parasitol, 87(3), 237-244. Abstract.  Author URL.
Dunkov BC, Guzov VM, Mocelin G, Shotkoski F, Brun A, Amichot M, Ffrench-Constant RH, Feyereisen R (1997). The Drosophila cytochrome P450 gene Cyp6a2: structure, localization, heterologous expression, and induction by phenobarbital. DNA Cell Biol, 16(11), 1345-1356. Abstract.  Author URL.
Brotz TM, Bochenek B, Aronstein K, Ffrench-Constant RH, Borst A (1997). gamma-Aminobutyric acid receptor distribution in the mushroom bodies of a fly (Calliphora erythrocephala): a functional subdivision of Kenyon cells?. J Comp Neurol, 383(1), 42-48. Abstract.  Author URL.

1996

Dunkov BC, Rodriguez-Arnaiz R, Pittendrigh B, ffrench-Constant RH, Feyereisen R (1996). Cytochrome P450 gene clusters in. MGG Molecular & General Genetics, 251(3), 290-290.
Dunkov BC, Rodriguez-Arnaiz R, Pittendrigh B, ffrench-Constant RH, Feyereisen R (1996). Cytochrome P450 gene clusters in Drosophila melanogaster. Mol Gen Genet, 251(3), 290-297. Abstract.  Author URL.
Coustau C, Carkion Y, Nappi A, Shotkoski F, ffrench-Constant R (1996). Differential induction of antibacterial transcripts in Drosophila susceptible and resistant to parasitism by Leptopilina boulardi. Insect Mol Biol, 5(3), 167-172. Abstract.  Author URL.
Aronstein K, Auld V, Ffrench-Constant R (1996). Distribution of two GABA receptor-like subunits in the Drosophila CNS. Invert Neurosci, 2(2), 115-120. Abstract.  Author URL.
ffrench-Constant R (1996). Ecological and evolutionary aspects of insecticide resistance by John A. McKenzie Academic Press, 1996. £52.00 hbk (185 pages) ISBN 0 12 484825 7. Trends in Ecology & Evolution, 11(9), 391-392.
Shotkoski F, Morris AC, James AA, ffrench-Constant RH (1996). Functional analysis of a mosquito gamma-aminobutyric acid receptor gene promoter. Gene, 168(2), 127-133. Abstract.  Author URL.
Coustau C, Rocheleau T, Carton Y, Nappi AJ, ffrench-Constant RH (1996). Induction of a putative serine protease transcript in immune challenged Drosophila. Dev Comp Immunol, 20(4), 265-272. Abstract.  Author URL.
Hidayat P, Phillips TW, Ffrench-Constant RH (1996). Molecular and Morphological Characters Discriminate Sitophilus oryzae and S. zeamais (Coleoptera: Curculionidae) and Confirm Reproductive Isolation. Annals of the Entomological Society of America, 89(5), 645-652.
Shotkoski F, Zhang HG, Jackson MB, ffrench-Constant RH (1996). Stable expression of insect GABA receptors in insect cell lines. Promoters for efficient expression of Drosophila and mosquito Rdl GABA receptors in stably transformed mosquito cell lines. FEBS Lett, 380(3), 257-262. Abstract.  Author URL.
Pittendrigh BR, Mocelin G, Andreev O, ffrench-Constant RH (1996). The sequence of a Drosophila Cyp4e2 cytochrome P450-encoding cDNA. Gene, 179(2), 295-296. Abstract.  Author URL.

1995

Brun LO, Borsa P, Gaudichon V, Stuart JJ, Aronstein K, Coustau C, ffrench-Constant RH (1995). 'Functional' haplodiploidy. Nature, 374(6522), 506-506.
Coustau C, ffrench‐Constant R (1995). Detection of cyclodiene insecticide resistance‐associated mutations by single‐stranded conformational polymorphism analysis. Pest Management Science, 43(4), 267-271.
Brun LO, Stuart J, Gaudichon V, Aronstein K, French-Constant RH (1995). Functional haplodiploidy: a mechanism for the spread of insecticide resistance in an important international insect pest. Proceedings of the National Academy of Sciences, 92(21), 9861-9865. Abstract.
Stilwell GE, Rocheleau T, ffrench-Constant RH (1995). GABA receptor minigene rescues insecticide resistance phenotypes in Drosophila. J Mol Biol, 253(2), 223-227. Abstract.  Author URL.
Aronstein K, Ffrench-Constant R (1995). Immunocytochemistry of a novel GABA receptor subunit Rdl in Drosophila melanogaster. Invert Neurosci, 1(1), 25-31. Abstract.  Author URL.
Aronstein K, Ode P, ffrench-Constant RH (1995). PCR based monitoring of specific Drosophila (Diptera: Drosophilidae) cyclodiene resistance alleles in the presence and absence of selection. Bulletin of Entomological Research, 85(1), 5-9.
Ffrench‐Constant R, Aronstein K, Anthony N, Coustau C (1995). Polymerase chain reaction‐based monitoring techniques for the detection of insecticide resistance‐associated point mutations and their potential applications. Pest Management Science, 43(3), 195-200.
Al-Aboodi A, Ffrench-Constant RH (1995). RAPD PCR confirms absence of genetic variation between insecticide resistant variants of the green peach aphid, Myzus persicae (Homoptera: Aphididae). Great Lakes entomologist., 28(2), 127-133.
Zhang HG, Lee HJ, Rocheleau T, ffrench-Constant RH, Jackson MB (1995). Subunit composition determines picrotoxin and bicuculline sensitivity of Drosophila gamma-aminobutyric acid receptors. Mol Pharmacol, 48(5), 835-840. Abstract.  Author URL.
FFRENCH‐CONSTANT RH (1995). The Zap Trap. The Sciences, 35(2), 31-35.

1994

Andreev D, Rocheleau T, Phillips TW, Beeman RW, ffrench‐Constant RH (1994). A PCR diagnostic for cyclodiene insecticide resistance in the red flour beetle Tribolium castaneum. Pest Management Science, 41(4), 345-349.
ffrench-Constant RH, Steichen JC, Brun LO (1994). A molecular diagnostic for endosulfan insecticide resistance in the coffee berry borer Hypothenemus hampei (Coleoptera: Scolytidae). Bulletin of Entomological Research, 84(1), 11-15.
Zhang HG, ffrench-Constant RH, Jackson MB (1994). A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms. J Physiol, 479 ( Pt 1), 65-75. Abstract.  Author URL.
Shotkoski F, Lee HJ, Zhang HG, Jackson MB, ffrench-Constant RH (1994). Functional expression of insecticide-resistant GABA receptors from the mosquito Aedes aegypti. Insect Mol Biol, 3(4), 283-287. Abstract.  Author URL.
Ffrench-Constant RH, Steichen JC, Shotkoski F (1994). Polymerase chain reaction diagnostic for cyclodiene insecticide resistance in the mosquito Aedes aegypti. Med Vet Entomol, 8(1), 99-100. Author URL.
Ffrench-Constant RH (1994). The molecular and population genetics of cyclodiene insecticide resistance. Insect Biochem Mol Biol, 24(4), 335-345. Abstract.  Author URL.

1993

Ffrench-Constant RH, Rocheleau TA, Steichen JC, Chalmers AE (1993). A point mutation in a Drosophila GABA receptor confers insecticide resistance. Nature, 363(6428), 449-451. Abstract.  Author URL.
ffrench-Constant RH, Steichen JC, Rocheleau TA, Aronstein K, Roush RT (1993). A single-amino acid substitution in a gamma-aminobutyric acid subtype a receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations. Proc Natl Acad Sci U S A, 90(5), 1957-1961. Abstract.  Author URL.
Thompson M, Shotkoski F, ffrench-Constant R (1993). Cloning and sequencing of the cyclodiene insecticide resistance gene from the yellow fever mosquito Aedes aegypti. Conservation of the gene and resistance associated mutation with Drosophila. FEBS Lett, 325(3), 187-190. Abstract.  Author URL.
ffrench-Constant RH (1993). Cloning of a putative GABAA receptor from cyclodiene-resistant Drosophila: a case study in the use of insecticide-resistant mutants to isolate neuroreceptors. In  (Ed) Comparative Molecular Neurobiology, 210-223.
ffrench-Constant RH (1993). Cloning of a putative GABAA receptor from cyclodiene-resistant Drosophila: a case study in the use of insecticide-resistant mutants to isolate neuroreceptors. EXS, 63, 210-223. Abstract.  Author URL.
Ffrench-Constant RH (1993). Cloning of the Drosophila cyclodiene insecticide resistance gene: a novel GABAA receptor subtype?. Comp Biochem Physiol C Comp Pharmacol Toxicol, 104(1), 9-12. Abstract.  Author URL.
Thompson M, Steichen JC, ffrench-Constant RH (1993). Conservation of cyclodiene insecticide resistance-associated mutations in insects. Insect Mol Biol, 2(3), 149-154. Abstract.  Author URL.
ffrench-Constant RH, Roush RT, Cariño FA (1993). Drosophila as a Tool for Investigating the Molecular Genetics of Insecticide Resistance. In  (Ed) Molecular Approaches to Fundamental and Applied Entomology, 1-37.
ffrench-Constant RH, Rocheleau TA (1993). Drosophila gamma-aminobutyric acid receptor gene Rdl shows extensive alternative splicing. J Neurochem, 60(6), 2323-2326. Abstract.  Author URL.
Lee HJ, Rocheleau T, Zhang HG, Jackson MB, ffrench-Constant RH (1993). Expression of a Drosophila GABA receptor in a baculovirus insect cell system. Functional expression of insecticide susceptible and resistant GABA receptors from the cyclodiene resistance gene Rdl. FEBS Lett, 335(3), 315-318. Abstract.  Author URL.

1992

Ffrench-Constant RH, Roush RT (1992). Cloning of a locus associated with cyclodiene resistance in Drosophila: a model system in a model insect. ACS symposium series. American Chemical Society(505), 90-98. Abstract.
Ffrench-Constant RH, Roush RT (1992). Cloning of an Invertebrate GABA Receptor from the Cyclodiene Resistance Locus in Drosophila. In  (Ed) Neurotox ’91, 285-292.
ffrench-Constant RH, Rocheleau T (1992). Drosophila cyclodiene resistance gene shows conserved genomic organization with vertebrate gamma-aminobutyric acidA receptors. J Neurochem, 59(4), 1562-1565. Abstract.  Author URL.
Bloomquist JR, Roush RT, ffrench-Constant RH (1992). Reduced neuronal sensitivity to dieldrin and picrotoxinin in a cyclodiene-resistant strain of Drosophila melanogaster (Meigen). Arch Insect Biochem Physiol, 19(1), 17-25. Abstract.  Author URL.
ffrench-Constant RH, Aronstein K, Roush RT (1992). Use of a P-element mediated germline transformant to study the effect of gene dosage in cyclodiene insecticide-resistant Drosophila melanogaster (Meigen). Pesticide Biochemistry and Physiology, 43(1), 78-84.

1991

Bloomquist JR, Ffrench‐Constant RH, Roush RT (1991). Excitation of central neurons by dieldrin and picrotoxinin in susceptible and resistant Drosophila melanogaster (meigen). Pest Management Science, 32(4), 463-469.
Ffrench-Constant RH, Roush RT (1991). Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.). Genet Res, 57(1), 17-21. Abstract.  Author URL.
Ffrench-Constant RH, Mortlock DP, Shaffer CD, MacIntyre RJ, Roush RT (1991). Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate gamma-aminobutyric acid subtype a receptor locus. Proc Natl Acad Sci U S A, 88(16), 7209-7213. Abstract.  Author URL.

1990

Ffrench-Constant RH, Roush RT, Mortlock D, Dively GP (1990). Isolation of dieldrin resistance from field populations of Drosophila melanogaster (Diptera: Drosophilidae). J Econ Entomol, 83(5), 1733-1737. Abstract.  Author URL.
ffrench-Constant RH, Roush RT, MacIntyre RJ (1990). Isolation, Characterization and Progress in Cloning of Cyclodiene Insecticide Resistance in Drosophila melanogaster. In  (Ed) Molecular Insect Science, 41-48.
ffrench-Constant RH, Roush RT (1990). Resistance Detection and Documentation: the Relative Roles of Pesticidal and Biochemical Assays. In  (Ed) Pesticide Resistance in Arthropods, 4-38.
Lines JD, ffRench-Constant RH, Kasim SH (1990). Testing Anopheles albimanus for genetic linkage of insecticide resistance genes by combining insecticide bioassay and biochemical methods. Med Vet Entomol, 4(4), 445-450. Abstract.  Author URL.

1989

Field LM, Devonshire AL, Ffrench-Constant RH, Forde BG (1989). Changes in DNA methylation are associated with loss of insecticide resistance in the peach‐potato aphid Myzus persicae (Sulz.). FEBS Letters, 243(2), 323-327.
Moores GD, Ffrench‐Constant RH, Devonshire AL (1989). Immunoassay for detecting insecticide resistance in aphids. Pest Management Science, 26(3), 324-326.
Ffrench-Constant RH, Bonning BC (1989). Rapid microtitre plate test distinguishes insecticide resistant acetylcholinesterase genotypes in the mosquitoes Anopheles albimanus, An. nigerrimus and Culex pipiens. Med Vet Entomol, 3(1), 9-16. Abstract.  Author URL.
Harrington R, Bartlet E, Riley DK, ffrench-Constant RH, Clark SJ (1989). Resurgence of insecticide-resistant Myzus persicae on potatoes treated repeatedly with cypermethrin and mineral oil. Crop Protection, 8(5), 340-348.
Field LM, Devonshire AL, ffrench-Constant RH, Forde BG (1989). The combined use of immunoassay and a DNA diagnostic technique to identify insecticide-resistant genotypes in the peach-potato aphid, Myzus persicae (Sulz.). Pesticide Biochemistry and Physiology, 34(2), 174-178.

1988

Ffrench-Constant RH, Clark SJ, Devonshire AL (1988). Effect of decline of insecticide residues on selection for insecticide resistance in Myzus persicae (Sulzer) (Hemiptera: Aphididae). Bulletin of Entomological Research, 78(1), 19-29.
ffrench-Constant RH, Harrington R, Devonshire AL (1988). Effect of repeated applications of insecticides to potatoes on numbers of Myzus persicae (Sulzer) (Hemiptera: Aphididae) and on the frequencies of insecticide-resistant variants. Crop Protection, 7(1), 55-61.
French-Constant RH, Byrne FJ, Stribley MF, Devonshire AL (1988). Rapid identification of the recently recognised Myzus antirrhinii (Macchiati) (Hemiptera: Aphididae) by polyacrylamide gel electrophoresis. Entomologist., 107(1), 20-23.
Ffrench-Constant RH, Devonshire AL, White RP (1988). Spontaneous loss and reselection of resistance in extremely resistant Myzus persicae (Sulzer). Pesticide Biochemistry and Physiology, 30(1), 1-10.

1987

ffrench-Constant RH, Devonshire AL (1987). A multiple homogenizer for rapid sample preparation in immunoassays and electrophoresis. Biochem Genet, 25(7-8), 493-499. Abstract.  Author URL.
Ffrench-Constant RH, Devonshire AL, Clark SJ (1987). Differential rate of selection for resistance by carbamate, organophosphorus and combined pyrethroid and organophosphorus insecticides in Myzus persicae (sulzer) (Hemiptera: Aphididae). Bulletin of Entomological Research, 77(2), 227-238.

1986

Devonshire AL, Moores GD, Ffrench-Constant RH (1986). Detection of insecticide resistance by immunological estimation of carboxylesterase activity in Myzus persicae (Sulzer) and cross reaction of the antiserum with Phorodon humuli (Schrank) (Hemiptera: Aphididae). Bulletin of Entomological Research, 76(1), 97-107.
Ffrench-Constant RH, Devonshire AL (1986). Effect of different insecticides on the selection and control of highly resistant Myzus persicae.
Ffrench-Constant RH, Devonshire AL (1986). The effect of aphid immigration on the rate of selection of insecticide resistance in Myzus persicae by different classes of insecticides. Aspects of applied biology(13), 115-125.

richard_ffrench-constant Details from cache as at 2022-08-07 16:08:16

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External Engagement and Impact

Awards/Honorary fellowships

2001 Royal Society Merit Award, University of Bath


Committee/panel activities

Dorothy Hodgkin Fellowship Panel (Royal Society)


Editorial responsibilities

2007-Present Invertebrate Neuroscience

1997-Present Pesticide Biochemistry and Physiology

1995-Present Pest Management Science

Research expeditions:

Photorhabdus collection in the Amazon, Brazil (2000);

Photorhabdus and Xenorhabdus collection in Vietnam (as part of FP7 grant GAMEXP)(2010);

Photorhabdus and Xenorhabdus collection in Thailand (as part of FP7 grant GAMEXP)(2011)


Invited lectures

8th European Congress of Entomology, Izmir, Turkey (2006);

International Congress of Pesticide Chemistry, Kobe, Japan (2006);

Society for Invertebrate Pathology, Quebec City, Canada (2007);

11th European Meeting of the IOBC/WPRS Working group, Ales, France (2007);

American Chemical Society meeting, Chicago, USA (2007);

Society for Invertebrate Pathology, University of Warwick, UK (2008);

International Congress of Entomology, Durban, South Africa (2008);

International P450 Meeting, Nice, France (2008);

International meeting of Toxinology, Recife, Brazil (2009);

Metabolism meets virulence, Munich, Germany (2009);

ETOX International Toxinology meeting, Obernai France (2009);

International Meeting on Pathogen Genomics, Pasteur, France (2010);

Mahidol Tropical Medicine Unit, Bangkok, Thailand (2011);

International Nematology Meeting, Corvallis, USA (2011)

Teaching

Undergraduate

  • BIO1411 Genetics
  • Dorset Fieldcourse
  • South Africa Fieldcourse

I also supervise student research projects about the relationships between moths and anthropogenic lights, and chough foraging on grasslands.

Modules

2021/22


Supervision / Group

Postdoctoral researchers

Postgraduate researchers

  • Nikos Karatolos
  • Robin Somers-Yeates

Alumni

  • Nicola Chamberlain (PhD)
  • Ritika Chauhan
  • Melanie Smee
  • Damien Smith

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