Dr Jonathan Ball
Senior Research Fellow
J.Ball@exeter.ac.uk
Not Known
Geoffrey Pope 223
Geoffrey Pope Building, University of Exeter , Stocker Road, Exeter, EX4 4QD, UK
Overview
I joined Exeter University from AstraZeneca as part of the Zebrafish Research team in May 2014.
I have considerable experience of environmental toxicology from my Ph.D and post-doctoral research on the effects of Ethinyl oestradiol on gene expression and sexual development of the Zebrafish, and investigating the effects of environmental pollutants on a range of fish species, respectively.
For 7 years I have worked in external commercial industry using the Zebrafish as a toxicity model with 5 years based at Brixham Environmental research Laboratories working for AstraZeneca. At AstraZeneca I was the technical lead for non-mammalian alternatives for the assessment of Developmental Toxicology. Recognized as an industry expert and the industry technical lead for an international consortium of five leading pharmaceutical companies (AZ, Pfizer, BMS, Amgen and Abbott), who joined forces to standardise the Zebrafish Developmental toxicity assay.
Initiated and led the training of technical experts across the consortia. Supporting a new research collaboration to identify novel complimentary techniques using the Zebrafish model, to extend its application and to encourage wider acceptance and usage within industry. Use my knowledge and expertise to support research colleagues in the development of other novel zebrafish assays for the assessment of human safety.
Broad research specialisms:
- Zebrafish
- Developmental toxicity
- Environmental safety
- Human safety
Qualifications
1996-2000 B.Sc., Biochemistry, Cardiff University
2000-2004 Ph.D., Biology, Exeter University
Career
2004-2007: Research technician, University of Exeter
2007-2009: Research Scientist Summit Plc
2009-2014: Research Scientist Safety, Health and Environment (SHE) specialist
Brixham Environmental Laboratory, AstraZeneca
2014-Present: Research Fellow, University of Exeter
Research group links
Research
Research interests
- Developmental biology
- Zebrafish
- Drug safety
- Alternative models
Research projects
Pharmaceutical industrial partnership for the assesment for developmental toxicity
Agrochemical industrial partnership for the assesment for developmental toxicity
Confidence in Concept Platform: Promoting Innovation and collaboration: Translational Medicine in Exeter 2 (PICTME2) - MRC
European Teratology Society Zebrafish Research Project
Estimation of volume and morphological abnormalities in larval zebrafish using machine learning
Research networks
Europeant Teratology Society (Zebrafish)
Ecotoxicology and Aquatic Biology Research Group
Publications
Journal articles
Chapters
Conferences
External Engagement and Impact
Committee/panel activities
Bioscience EDI
Invited lectures
British Teratogenic Society 2013
European Teratogenic Society 2013
Journal and book series Editorships and Editorial board membership
Frontiers in Toxicology as Review Editor for the Developmental and Reproductive Toxicology section