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Faculty of Health and Life Sciences

 Rafael Da-Silva-Custodio

Rafael Da-Silva-Custodio

Postdoctoral Researcher

 R.C.Da-Silva-Custodio@exeter.ac.uk

 Environment and Sustainability Institute 

 

Environment and Sustainability Institute, University of Exeter, Penryn Campus, Penryn, Cornwall, TR10 9FE, UK


Overview

Qualifications

2009 MSc in Microbiology, University of Aveiro, Portugal
2008 Degree in Biology, University of Evora, Portugal

Career

2010-2012 Research Fellow, Institute for Molecular and Cell Biology, Porto, Portugal

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Research

Research projects

Project Title: “Sphingosine-1-phosphate lyases as novel therapeutic targets in intracellular bacteria”

Supervisors: Dr Alan Brown and Dr Mitali Sarkar-Tyson

Funding Body: Defence Science and Technology Laboratory (Dstl)

Publications/Presentations:

Almeida MT, Mesquita FS, Cruz R, Osório H, Custódio R, Brito C, Vingadassalom D, Martins M, Leong JM, Holden DW, Cabanes D, Sousa S. (2015) Src-dependent Tyrosine Phosphorylation of Non-muscle Myosin Heavy Chain-IIA Restricts Listeria monocytogenes Cellular Infection. J Biol Chem. 2015 Jan 29. pii: jbc.M114.591313

Martins, M., Custodio, R., Camejo, A., Almeida, M.T., Cabanes, D. and Sousa, S. (2012) Listeria monocytogenes Triggers the Cell Surface Expression of Gp96 Protein and Interacts with Its N Terminus to Support Cellular Infection. THE JOURNAL OF BIOLOGICAL CHEMISTRY, VOL. 287, NO. 51, pp. 43083–43093

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